scholarly journals Predicting Regional Outbreaks of Hepatitis A Using 3D LSTM and Open Data in Korea

Electronics ◽  
2021 ◽  
Vol 10 (21) ◽  
pp. 2668
Author(s):  
Kwangok Lee ◽  
Munkyu Lee ◽  
Inseop Na

In 2020 and 2021, humanity lived in fear due to the COVID-19 pandemic. However, with the development of artificial intelligence technology, mankind is attempting to tackle many challenges from currently unpredictable epidemics. Korean society has been exposed to various infectious diseases since the Korean War in 1950, and to overcome them, the six most serious cases in National Notifiable Infectious Diseases (NNIDs) category I were defined. Although most infectious diseases have been overcome, viral hepatitis A has been on the rise in Korean society since 2010. Therefore, in this paper, the prediction of viral hepatitis A, which is rapidly spreading in Korean society, was predicted by region using the deep learning technique and a publicly available dataset. For this study, we gathered information from five organizations based on the open data policy: Korea Centers for Disease Control and Prevention (KCDC), National Institute of Environmental Research (NIER), Korea Meteorological Agency (KMA), Public Open Data Portal, and Korea Environment Corporation (KECO). Patient information, water environment information, weather information, population information, and air pollution information were acquired and correlations were identified. Next, an epidemic outbreak prediction was performed using data preprocessing and 3D LSTM. The experimental results were compared with various machine learning methods through RMSE. In this paper, we attempted to predict regional epidemic outbreaks of hepatitis A by linking the open data environment with deep learning. It is expected that the experimental process and results will be used to present the importance and usefulness of establishing an open data environment.

1997 ◽  
Vol 78 (1) ◽  
pp. 50-50
Author(s):  
L. S. Kalyagina ◽  
E. A. Manakova ◽  
D. A. Krause

The aim of this work was to study the peculiarities of course and outcomes of viral hepatitis A (VHA) in children with acute dysentery Flexner's disease. The results of the study are based on clinical and laboratory examination data of Nizhny Novgorod Children's Hepatitis Center at Infectious Diseases Hospital No. 23 in 1989. 18 children at the age from 3 to 14 years old, who had and had recovered from VGA and acute dysentery Flexner's disease. Mild jaundice form of the disease was found in 2/3 of the children, and moderate - in 1/3 of the children. More than 2/3 of patients were boys of school age.


2020 ◽  
Vol 22 (4) ◽  
pp. 100-106
Author(s):  
N. P. Khirina ◽  
V. M. Dobrynin ◽  
A. V. Stepanov ◽  
N. N. Stepanov ◽  
S. V. Popov ◽  
...  

Experimental study of specific activity and harmlessness of simultaneous application of five vaccines (abdominal, Zonne dysentery, viral hepatitis A, meningococcal and live yellow fever vaccine) in complex immunoprophylaxis of dangerous infectious diseases was carried out. It has been found that the simultaneous administration of these vaccines is safe and has high immunogenicity and protective efficacy for each infection not inferior to, and in some cases superior to, vaccines administered separately. In particular, the immunogenicity of vaccines against typhoid fever and viral hepatitis A administered jointly was four times higher than with their separate administration, which may indicate the presence of a certain adjuvant effect on the part of other vaccines, as well as the absence of antagonism in their joint use. It was revealed that complex vaccinations do not negatively affect the functional state of cells involved in the initial stage of immunogenesis. The absence of a negative effect of complex vaccinations on the components of nonspecific resistance of the body was almost completely confirmed in the conditions of infection of immunized animals with influenza virus, that is, in modeling heterologous infection. In addition, immunization with a complex of vaccines does not lead to allergic animals, which is confirmed by the absence of any manifestations of allergic reactions or anaphylactic activity.


2011 ◽  
Vol 1 (1) ◽  
pp. 31-35
Author(s):  
Zarema Obradović ◽  
Arzija Pašalić ◽  
Amar Žilić

Introduction: Gastrointestinal infectious diseases are a group of frequent diseases in developing countries as a result of industrialization in food production and often consuming of the food in public places. In Bosnia and Herzegovina and in Canton Sarajevo these diseases are frequent. The aim of this work is to investigate epidemiological characteristics of the most often gastrointestinal infectious diseases in Canton Sarajevo (Enterocolitis acuta, Toxiinfectio alimentaris, Salmonellosis, Amoebiasis) compared with Viral Hepatitis A and to estimate the need for the implementation of vaccination against this disease.Methods: We used individual reports as well as monthly and annual bulletins about the movement of infectious diseases which are obligatory for reporting from the Epidemiology department of the Institute for public health in Canton Sarajevo. This work is a retrospective study, for the period 2005-2009. Descriptive- analytical method was used. In statistical processing we used mean, structure index and trend index.Results: The research showed that gastrointestinal infectious diseases are registered in a huge number in all the observed years. The most often was Enterocolitis acuta, and the rarest was Viral Hepatitis A. The diseases were mostly sporadic. Distinct seasonality and coherence with warm months in the year is expressed in Enterocolitis acuta and Intoxicatio alimentaris, while the other diseases are registered during the whole year.Conclusions: Incidence of gastrointestinal infectious diseases in Canton Sarajevo is high and we need to work intensively to improve sanitary conditions as the most eficient preventive measures. There is no justification for implementing of the vaccine against Viral hepatitis A.


2018 ◽  
Vol 69 (3) ◽  
pp. 747-751 ◽  
Author(s):  
Daniela Gabriela Badita ◽  
Iulia Ioana Stanescu ◽  
Andra Balcangiu Stroescu ◽  
Dan Piperea Sianu ◽  
Daniela Miricescu ◽  
...  

Viral hepatitis represents a major health problem worldwide. Approximately 1.4 million people are infected with hepatitis A virus every year, although given that most of the cases evolve asymptomatically the real number could be even higher. At the same time, hepatitis B virus affects up to 30% of the world population and represents one of the main causes of cirrhosis and hepatocellular carcinoma. Thus, it is very important to understand the physiopathology of viral hepatitis A and B not only for the diagnosis, but also for the therapeutic protocol. The present research aimed to determine if HAV and HBV can alter serum and salivary levels of total protein and of 2 important electrolytes: calcium and potassium.


2020 ◽  
pp. 79-82
Author(s):  
Nataliia Volodymyrivna Shepylieva ◽  
Alla Oleksandrivna Shvaichenko

A global problem for humanity is the wide spread of HCV carriers worldwide. To address this, the WHO has developed a global strategy for the health sector to eliminate viral hepatitis and has set the following goals: to reduce the number of new cases of chronic hepatitis B and C by 90 % by 2030 as well as to reduce the quantity of death from these infections by 65 %. It is emphasized that the development of infectious or somatic disease on the background of chronic viral hepatitis requires a more careful approach and thorough medical correction, as their course and prognosis can be significantly aggravated. The case of viral hepatitis A, which occurred on a background of previously undiagnosed HCV infection and resulted in a death, has been described. Thus, previously undiagnosed HCV infection exacerbated the course of a self−eliminating disease, such as hepatitis A, and resulted in a death. Therefore, expanding the screening for viral hepatitis will allow identifying infected individuals and conducting antiviral therapy and preventive measures, which will reduce the incidence and mortality rates. Key words: viral hepatitis A, viral hepatitis C, chronic HCV−infection, diagnosis, treatment, outcome.


PLoS ONE ◽  
2009 ◽  
Vol 4 (12) ◽  
pp. e8467 ◽  
Author(s):  
Jian Lu ◽  
Yongdong Zhou ◽  
Xiaojing Lin ◽  
Yongzhen Jiang ◽  
Ruiguang Tian ◽  
...  

2018 ◽  
Vol 68 (1) ◽  
pp. 167-184 ◽  
Author(s):  
Stanley M. Lemon ◽  
Jördis J. Ott ◽  
Pierre Van Damme ◽  
Daniel Shouval

2008 ◽  
Vol 13 (40) ◽  
Author(s):  
K Fabianova ◽  
J Cástková ◽  
C Beneš ◽  
J Kyncl ◽  
B Kriz

The public health protection authorities in the Czech Republic report a rise in cases of viral hepatitis A (HAV) since the end of May 2008. In total, as many as 602 HAV cases have been reported in 2008 until the end of calendar week 39 (28 September).


2015 ◽  
Vol 24 (5) ◽  
pp. 829-836 ◽  
Author(s):  
Maciej Bura ◽  
Michał Michalak ◽  
Michał Chojnicki ◽  
Arleta Kowala-Piaskowska ◽  
Iwona Mozer-Lisewska

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