scholarly journals Optimizing the Performance of Breast Cancer Classification by Employing the Same Domain Transfer Learning from Hybrid Deep Convolutional Neural Network Model

Electronics ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 445 ◽  
Author(s):  
Laith Alzubaidi ◽  
Omran Al-Shamma ◽  
Mohammed A. Fadhel ◽  
Laith Farhan ◽  
Jinglan Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Deep Learning ◽  
Transfer Learning ◽  
Cancer Diagnosis ◽  
Classification Accuracy ◽  
Cancer Classification ◽  
Learning Models ◽  
Proposed Model ◽  
Domain Transfer ◽  
Domain Transfer Learning

Breast cancer is a significant factor in female mortality. An early cancer diagnosis leads to a reduction in the breast cancer death rate. With the help of a computer-aided diagnosis system, the efficiency increased, and the cost was reduced for the cancer diagnosis. Traditional breast cancer classification techniques are based on handcrafted features techniques, and their performance relies upon the chosen features. They also are very sensitive to different sizes and complex shapes. However, histopathological breast cancer images are very complex in shape. Currently, deep learning models have become an alternative solution for diagnosis, and have overcome the drawbacks of classical classification techniques. Although deep learning has performed well in various tasks of computer vision and pattern recognition, it still has some challenges. One of the main challenges is the lack of training data. To address this challenge and optimize the performance, we have utilized a transfer learning technique which is where the deep learning models train on a task, and then fine-tune the models for another task. We have employed transfer learning in two ways: Training our proposed model first on the same domain dataset, then on the target dataset, and training our model on a different domain dataset, then on the target dataset. We have empirically proven that the same domain transfer learning optimized the performance. Our hybrid model of parallel convolutional layers and residual links is utilized to classify hematoxylin–eosin-stained breast biopsy images into four classes: invasive carcinoma, in-situ carcinoma, benign tumor and normal tissue. To reduce the effect of overfitting, we have augmented the images with different image processing techniques. The proposed model achieved state-of-the-art performance, and it outperformed the latest methods by achieving a patch-wise classification accuracy of 90.5%, and an image-wise classification accuracy of 97.4% on the validation set. Moreover, we have achieved an image-wise classification accuracy of 96.1% on the test set of the microscopy ICIAR-2018 dataset.

scholarly journals Transfer Learning with Convolutional Neural Networks for Diabetic Retinopathy Image Classification. A Review

2020 ◽  
Vol 10 (6) ◽  
pp. 2021 ◽  
Author(s):  
Ibrahem Kandel ◽  
Mauro Castelli
Keyword(s):  
Diabetic Retinopathy ◽  
Deep Learning ◽  
Transfer Learning ◽  
Main Idea ◽  
Diabetic Patients ◽  
Domain Transfer ◽  
Domain Transfer Learning ◽  
Enormous Number ◽  
Deep Learning Model

Diabetic retinopathy (DR) is a dangerous eye condition that affects diabetic patients. Without early detection, it can affect the retina and may eventually cause permanent blindness. The early diagnosis of DR is crucial for its treatment. However, the diagnosis of DR is a very difficult process that requires an experienced ophthalmologist. A breakthrough in the field of artificial intelligence called deep learning can help in giving the ophthalmologist a second opinion regarding the classification of the DR by using an autonomous classifier. To accurately train a deep learning model to classify DR, an enormous number of images is required, and this is an important limitation in the DR domain. Transfer learning is a technique that can help in overcoming the scarcity of images. The main idea that is exploited by transfer learning is that a deep learning architecture, previously trained on non-medical images, can be fine-tuned to suit the DR dataset. This paper reviews research papers that focus on DR classification by using transfer learning to present the best existing methods to address this problem. This review can help future researchers to find out existing transfer learning methods to address the DR classification task and to show their differences in terms of performance.

scholarly journals A Deep Convolutional Neural Network Architecture for Cancer Diagnosis using Histopathological Images

2021 ◽  
Vol 10 (12) ◽  
pp. 7-12
Author(s):  
Karthika Gidijala ◽  
◽  
Mansa Devi Pappu ◽  
Manasa Vavilapalli ◽  
Mahesh Kothuru ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neural Network ◽  
Neural Networks ◽  
Decision Making ◽  
Deep Learning ◽  
Cancer Diagnosis ◽  
Network Architecture ◽  
Neural Network Architecture ◽  
Proposed Model ◽  
Histopathological Images

Many different models of Convolution Neural Networks exist in the Deep Learning studies. The application and prudence of the algorithms is known only when they are implemented with strong datasets. The histopathological images of breast cancer are considered as to have much number of haphazard structures and textures. Dealing with such images is a challenging issue in deep learning. Working on wet labs and in coherence to the results many research have blogged with novel annotations in the research. In this paper, we are presenting a model that can work efficiently on the raw images with different resolutions and alleviating with the problems of the presence of the structures and textures. The proposed model achieves considerably good results useful for decision making in cancer diagnosis.

scholarly journals Predicting Breast Cancer Gene Expression Signature by Applying Deep Convolutional Neural Networks From Unannotated Pathological Images

2021 ◽  
Vol 11 ◽  
Author(s):  
Nam Nhut Phan ◽  
Chi-Cheng Huang ◽  
Ling-Ming Tseng ◽  
Eric Y. Chuang
Keyword(s):  
Breast Cancer ◽  
Deep Learning ◽  
Transfer Learning ◽  
Gene Expression Signature ◽  
Learning Approaches ◽  
Breast Cancer Patients ◽  
Learning Models ◽  
Intrinsic Subtypes ◽  
Deep Convolutional Neural Networks ◽  
Cancer Subtypes

We proposed a highly versatile two-step transfer learning pipeline for predicting the gene signature defining the intrinsic breast cancer subtypes using unannotated pathological images. Deciphering breast cancer molecular subtypes by deep learning approaches could provide a convenient and efficient method for the diagnosis of breast cancer patients. It could reduce costs associated with transcriptional profiling and subtyping discrepancy between IHC assays and mRNA expression. Four pretrained models such as VGG16, ResNet50, ResNet101, and Xception were trained with our in-house pathological images from breast cancer patient with recurrent status in the first transfer learning step and TCGA-BRCA dataset for the second transfer learning step. Furthermore, we also trained ResNet101 model with weight from ImageNet for comparison to the aforementioned models. The two-step deep learning models showed promising classification results of the four breast cancer intrinsic subtypes with accuracy ranging from 0.68 (ResNet50) to 0.78 (ResNet101) in both validation and testing sets. Additionally, the overall accuracy of slide-wise prediction showed even higher average accuracy of 0.913 with ResNet101 model. The micro- and macro-average area under the curve (AUC) for these models ranged from 0.88 (ResNet50) to 0.94 (ResNet101), whereas ResNet101_imgnet weighted with ImageNet archived an AUC of 0.92. We also show the deep learning model prediction performance is significantly improved relatively to the common Genefu tool for breast cancer classification. Our study demonstrated the capability of deep learning models to classify breast cancer intrinsic subtypes without the region of interest annotation, which will facilitate the clinical applicability of the proposed models.

scholarly journals Vulnerability in Deep Transfer Learning Models to Adversarial Fast Gradient Sign Attack for COVID-19 Prediction from Chest Radiography Images

2021 ◽  
Vol 11 (9) ◽  
pp. 4233
Author(s):  
Biprodip Pal ◽  
Debashis Gupta ◽  
Md. Rashed-Al-Mahfuz ◽  
Salem A. Alyami ◽  
Mohammad Ali Moni
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
Chest Radiography ◽  
High Sensitivity ◽  
Ct Images ◽  
Classification Performance ◽  
Learning Models ◽  
X Ray ◽  
Image Capturing ◽  
Fast Gradient

The COVID-19 pandemic requires the rapid isolation of infected patients. Thus, high-sensitivity radiology images could be a key technique to diagnose patients besides the polymerase chain reaction approach. Deep learning algorithms are proposed in several studies to detect COVID-19 symptoms due to the success in chest radiography image classification, cost efficiency, lack of expert radiologists, and the need for faster processing in the pandemic area. Most of the promising algorithms proposed in different studies are based on pre-trained deep learning models. Such open-source models and lack of variation in the radiology image-capturing environment make the diagnosis system vulnerable to adversarial attacks such as fast gradient sign method (FGSM) attack. This study therefore explored the potential vulnerability of pre-trained convolutional neural network algorithms to the FGSM attack in terms of two frequently used models, VGG16 and Inception-v3. Firstly, we developed two transfer learning models for X-ray and CT image-based COVID-19 classification and analyzed the performance extensively in terms of accuracy, precision, recall, and AUC. Secondly, our study illustrates that misclassification can occur with a very minor perturbation magnitude, such as 0.009 and 0.003 for the FGSM attack in these models for X-ray and CT images, respectively, without any effect on the visual perceptibility of the perturbation. In addition, we demonstrated that successful FGSM attack can decrease the classification performance to 16.67% and 55.56% for X-ray images, as well as 36% and 40% in the case of CT images for VGG16 and Inception-v3, respectively, without any human-recognizable perturbation effects in the adversarial images. Finally, we analyzed that correct class probability of any test image which is supposed to be 1, can drop for both considered models and with increased perturbation; it can drop to 0.24 and 0.17 for the VGG16 model in cases of X-ray and CT images, respectively. Thus, despite the need for data sharing and automated diagnosis, practical deployment of such program requires more robustness.

scholarly journals An Investigation into the Application of Deep Learning in the Detection and Mitigation of DDOS Attack on SDN Controllers

Technologies ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 14
Author(s):  
James Dzisi Gadze ◽  
Akua Acheampomaa Bamfo-Asante ◽  
Justice Owusu Agyemang ◽  
Henry Nunoo-Mensah ◽  
Kwasi Adu-Boahen Opare
Keyword(s):  
Deep Learning ◽  
Network Architecture ◽  
Learning Algorithm ◽  
Single Point ◽  
Denial Of Service ◽  
Specific Work ◽  
Learning Models ◽  
Ddos Attack ◽  
Deep Learning Algorithm ◽  
Proposed Model

Software-Defined Networking (SDN) is a new paradigm that revolutionizes the idea of a software-driven network through the separation of control and data planes. It addresses the problems of traditional network architecture. Nevertheless, this brilliant architecture is exposed to several security threats, e.g., the distributed denial of service (DDoS) attack, which is hard to contain in such software-based networks. The concept of a centralized controller in SDN makes it a single point of attack as well as a single point of failure. In this paper, deep learning-based models, long-short term memory (LSTM) and convolutional neural network (CNN), are investigated. It illustrates their possibility and efficiency in being used in detecting and mitigating DDoS attack. The paper focuses on TCP, UDP, and ICMP flood attacks that target the controller. The performance of the models was evaluated based on the accuracy, recall, and true negative rate. We compared the performance of the deep learning models with classical machine learning models. We further provide details on the time taken to detect and mitigate the attack. Our results show that RNN LSTM is a viable deep learning algorithm that can be applied in the detection and mitigation of DDoS in the SDN controller. Our proposed model produced an accuracy of 89.63%, which outperformed linear-based models such as SVM (86.85%) and Naive Bayes (82.61%). Although KNN, which is a linear-based model, outperformed our proposed model (achieving an accuracy of 99.4%), our proposed model provides a good trade-off between precision and recall, which makes it suitable for DDoS classification. In addition, it was realized that the split ratio of the training and testing datasets can give different results in the performance of a deep learning algorithm used in a specific work. The model achieved the best performance when a split of 70/30 was used in comparison to 80/20 and 60/40 split ratios.

scholarly journals Study on Human Activity Recognition Using Semi-Supervised Active Transfer Learning

Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2760
Author(s):  
Seungmin Oh ◽  
Akm Ashiquzzaman ◽  
Dongsu Lee ◽  
Yeonggwang Kim ◽  
Jinsul Kim
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
Activity Recognition ◽  
Human Activity ◽  
Random Sampling ◽  
Data Gathering ◽  
Human Activity Recognition ◽  
Learning Models ◽  
Active Transfer ◽  
Existing Data

In recent years, various studies have begun to use deep learning models to conduct research in the field of human activity recognition (HAR). However, there has been a severe lag in the absolute development of such models since training deep learning models require a lot of labeled data. In fields such as HAR, it is difficult to collect data and there are high costs and efforts involved in manual labeling. The existing methods rely heavily on manual data collection and proper labeling of the data, which is done by human administrators. This often results in the data gathering process often being slow and prone to human-biased labeling. To address these problems, we proposed a new solution for the existing data gathering methods by reducing the labeling tasks conducted on new data based by using the data learned through the semi-supervised active transfer learning method. This method achieved 95.9% performance while also reducing labeling compared to the random sampling or active transfer learning methods.

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