scholarly journals Effects of NaCl and CaCl2 Salinization on Morpho-Anatomical and Physiological Traits of Potted Callistemon citrinus Plants

Forests ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1666
Author(s):  
Veronica De Micco ◽  
Carmen Arena ◽  
Chiara Amitrano ◽  
Youssef Rouphael ◽  
Stefania De Pascale ◽  
...  
Keyword(s):  
Structural Damage ◽  
Leaf Gas Exchange ◽  
Fluorescence Emission ◽  
Photosynthetic Performance ◽  
Saline Stress ◽  
Close Relationship ◽  
Osmotic Solution ◽  
Physiological Acclimation ◽  
Anatomical Parameters

The aim of this work was to assess the possible coordination mechanisms between leaf functional anatomical traits and physiological acclimation of potted Callistemon citrinus plants when subjected to two saline iso-osmotic solutions using NaCl or CaCl2. Digital image analysis was applied to quantify anatomical parameters with a specific focus on the occurrence of signs of structural damage as well as on alterations, such as the occurrence of shrunk tissues and accumulation of phenolic compounds. Morpho-anatomical analyses were accompanied by measurements of leaf gas exchange and chlorophyll fluorescence emission. Results showed that C. citrinus plants, when irrigated with the CaCl2 solution, induced a leaf morpho-anatomical structure which did not allow the maintenance of high photosynthetic performance under such conditions, compared to both controls and plants treated with the iso-osmotic solution of NaCl. Data collected seem to suggest a close relationship between anatomical traits and eco-physiological strategies in maintaining the photosynthetic efficiency under saline stress conditions and highlight the fundamental role of leaf anatomy in imposing the limits of plant physiology.

scholarly journals Hormonal and Hydroxycinnamic Acids Profiles in Banana Leaves in Response to Various Periods of Water Stress

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Jalel Mahouachi ◽  
María F. López-Climent ◽  
Aurelio Gómez-Cadenas
Keyword(s):  
Water Stress ◽  
Leaf Gas Exchange ◽  
Stomatal Closure ◽  
Photosynthetic Performance ◽  
Hydroxycinnamic Acids ◽  
Cinnamic Acids ◽  
Gas Exchange Parameters ◽  
Banana Leaves ◽  
Indole 3 Acetic Acid

The pattern of change in the endogenous levels of several plant hormones and hydroxycinnamic acids in addition to growth and photosynthetic performance was investigated in banana plants (Musa acuminatacv. “Grand Nain”) subjected to various cycles of drought. Water stress was imposed by withholding irrigation for six periods with subsequent rehydration. Data showed an increase in abscisic acid (ABA) and indole-3-acetic acid (IAA) levels, a transient increase in salicylic acid (SA) concentration, and no changes in jasmonic acid (JA) after each period of drought. Moreover, the levels of ferulic (FA) and cinnamic acids (CA) were increased, and plant growth and leaf gas exchange parameters were decreased by drought conditions. Overall, data suggest an involvement of hormones and hydroxycinnamic acids in plant avoidance of tissue dehydration. The increase in IAA concentration might alleviate the senescence of survival leaves and maintained cell elongation, and the accumulation of FA and CA could play a key role as a mechanism of photoprotection through leaf folding, contributing to the effect of ABA on inducing stomatal closure. Data also suggest that the role of SA similarly to JA might be limited to a transient and rapid increase at the onset of the first period of stress.

Lineages

2018 ◽  
Author(s):  
Ruth Gamble
Keyword(s):  
Thirteenth Century ◽  
Buddhist Tradition ◽  
Close Relationship

Chapter 2 examines lineages in Tibetan society and the Buddhist tradition and explains how they influenced the development of Tibet’s reincarnation lineages. It begins by explaining the role of family lineages in thirteenth-century Tibet, describing how lineages helped form identities, created links between people, and served as a mechanism for inheritance. It then examines the three main forms of Buddhist lineages—monastic, Mahāyāna, and Tantric—and shows how these lineages were often intermingled with Tibetan family lineages and inheritance practices. The chapter ends by outlining how lineages associated with manifestation, particularly lineages associated with Avalokiteśvara, underpinned claims by Tibetans to be the manifestation of this bodhisattva and other celestial beings. This chapter also explains how the Karmapas’ reincarnation lineage, traditions, and institutions were presented not as a break from other lineages but as an extension of them, and it highlights the close relationship between lineages and specific places.

Processing the Future

2018 ◽  
Author(s):  
Martin Giraudeau
Keyword(s):  
Venture Capital ◽  
Diagnostic Techniques ◽  
Business Administration ◽  
Knowledge Practices ◽  
Project Appraisal ◽  
Development Corporation ◽  
Close Relationship ◽  
Administrative Procedures ◽  
American Research

This chapter is an analysis of the project appraisal procedures in place at American Research and Development Corporation (ARD) between 1946 and 1973, under the management of Georges F. Doriot. It shows the importance of knowledge technologies and administrative procedures in the way the venture capital company dealt with uncertain futures. The origins of these knowledge practices are traced back to Georges F. Doriot’s own views on business and more generally to the pragmatist movement in business administration of which he was a member. The conduct of project appraisal at ARD is then observed directly, and this reveals its reliance on a rich set of knowledge and diagnostic techniques as well as administrative procedures. These observations allow for a specification of the nature and role of imagination in the entrepreneurship and venture capital practices examined here—in particular, its close relationship with organized knowledge.

scholarly journals POS0677 THE ROLE OF MUSCULOSKELETAL ULTRASOUND IN PREDICTING THE RESPONSE TO JAK INHIBITORS: RESULTS FROM A LARGE MONOCENTRIC COHORT

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 583-583
Author(s):  
C. Garufi ◽  
F. Ceccarelli ◽  
F. R. Spinelli ◽  
S. Mancuso ◽  
C. Pirone ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Structural Damage ◽  
Power Doppler ◽  
Response To Treatment ◽  
Jak Inhibitors ◽  
Inflammatory Score ◽  
Inflammatory Status

Background:In the management of chronic arthritis, such as Rheumatoid Arthritis (RA), Ultrasound (US) assessment can provide relevant information about the joint inflammatory status in the diagnostic phase and even more in the monitoring of disease activity and structural damage1,2.Objectives:In this longitudinal study, we aimed to assesse the role of US in predicting the efficacy of JAK-inhibitors (JAKi) in RA patients.Methods:We enrolled RA patients starting baricitinib or tofacitinib. All patients were evaluated at baseline and after 4, 12, 24, 48 weeks. Disease activity was calculated by DAS28CRP. US examination in 22 joints (I–V MCPs and PIPs, wrists) aimed at evaluating inflammatory features (synovial effusion and hypertrophy, power Doppler-PD), through a semi-quantitative scale (0-3). The total US (0-198) and PD (0-66) scores were calculated. We scanned bilateral flexor (I–V fingers of hands) and extensor compartments (1-6) tendons: tenosynovitis was scored as absent/present (0/1), resulting in a total score (0-22).Results:We studied 102 patients (M/F 15/87; median age 59.2 years, IQR 17.75; median disease duration 144 months, IQR 126), 61 treated with baricitinib and 41 with tofacitinib. At baseline, the median total US score was 18 (IQR 19) and the median PD score 2 (4). We observed a significant reduction in both total and PD US scores at all time-points (p<0.0001) (Figure 1). At baseline, 75.4% of patients showed tenosynovitis involving at least one tendon, with a median score of 2 (IQR 3.5) significantly decreasing after 24 weeks (p=0.02). Multivariate analysis, adjusted for baseline DAS28CRP and other concomitant treatments (including glucocorticoids and methotrexate treatment), confirmed the independent association between baseline US (PD and tenosynovitis) scores and the reduction of disease activity at follow-up evaluations.Conclusion:The present study confirmed the early efficacy of JAKi in RA patients by using US evaluation. Furthermore, power doppler and tenosynovitis scores could play a predictive role in response to treatment.References:[1]MUELLER RB, HASLER C, POPP F, et al. Effectiveness, Tolerability, and Safety of Tofacitinib in Rheumatoid Arthritis: A Retrospective Analysis of Real-World Data from the St. Gallen and Aarau Cohorts. J Clin Med. 2019;8(10):1548.[2]COLEBATCH AN, EDWARDS CJ, ØSTERGAARD M, et al. EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis. Ann Rheum Dis. 2013;72(6):804-14.Figure 1.Ultrasound inflammatory score (a) and Ultrasound Power Doppler (PD) score (b) at baseline and follow-up.Table 1.Baseline characteristics of 414 RA patients.WEEKS04122448US inflammatory score18 (19)11 (15.5)9.5 (11.7)7.5 (8)6 (11)US PD score2 (4)0 (2)0 (1)0 (1)0 (0.7)Disclosure of Interests:Cristina Garufi: None declared, Fulvia Ceccarelli: None declared, Francesca Romana Spinelli Speakers bureau: Abbvie, Eli Lilly, Consultant of: Gilead/Galapagos, Eli Lilly, Grant/research support from: Pfizer, Silvia Mancuso: None declared, Carmelo Pirone: None declared, Fabrizio Conti Speakers bureau: Abbvie, Eli Lilly, Sanofi, Pfizer, Consultant of: Gilead/Galapagos

scholarly journals Dietary Modulation of Bacteriophages as an Additional Player in Inflammation and Cancer

Cancers ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2036
Author(s):  
Luigi Marongiu ◽  
Markus Burkard ◽  
Sascha Venturelli ◽  
Heike Allgayer
Keyword(s):  
Structural Damage ◽  
Folk Medicine ◽  
Gastrointestinal Diseases ◽  
Potential Contribution ◽  
Anticancer Properties ◽  
Specific Phage ◽  
Microbial Network ◽  
Inflammatory Bowel ◽  
Species Specific

Natural compounds such as essential oils and tea have been used successfully in naturopathy and folk medicine for hundreds of years. Current research is unveiling the molecular role of their antibacterial, anti-inflammatory, and anticancer properties. Nevertheless, the effect of these compounds on bacteriophages is still poorly understood. The application of bacteriophages against bacteria has gained a particular interest in recent years due to, e.g., the constant rise of antimicrobial resistance to antibiotics, or an increasing awareness of different types of microbiota and their potential contribution to gastrointestinal diseases, including inflammatory and malignant conditions. Thus, a better knowledge of how dietary products can affect bacteriophages and, in turn, the whole gut microbiome can help maintain healthy homeostasis, reducing the risk of developing diseases such as diverse types of gastroenteritis, inflammatory bowel disease, or even cancer. The present review summarizes the effect of dietary compounds on the physiology of bacteriophages. In a majority of works, the substance class of polyphenols showed a particular activity against bacteriophages, and the primary mechanism of action involved structural damage of the capsid, inhibiting bacteriophage activity and infectivity. Some further dietary compounds such as caffeine, salt or oregano have been shown to induce or suppress prophages, whereas others, such as the natural sweeter stevia, promoted species-specific phage responses. A better understanding of how dietary compounds could selectively, and specifically, modulate the activity of individual phages opens the possibility to reorganize the microbial network as an additional strategy to support in the combat, or in prevention, of gastrointestinal diseases, including inflammation and cancer.

scholarly journals Protective role of foliar-applied nitric oxide in Triticum aestivum under saline stress

2013 ◽  
Vol 37 ◽  
pp. 1155-1165 ◽  
Author(s):  
Farhana KAUSAR ◽  
Muhammad SHAHBAZ ◽  
Muhammad ASHRAF
Keyword(s):  
Nitric Oxide ◽  
Triticum Aestivum ◽  
Protective Role ◽  
Saline Stress

How Can Economic Interests Influence Support for Free Trade?

2012 ◽  
Vol 66 (2) ◽  
pp. 311-328 ◽  
Author(s):  
Benjamin O. Fordham ◽  
Katja B. Kleinberg
Keyword(s):  
Trade Policy ◽  
Free Trade ◽  
Well Being ◽  
Economic Interests ◽  
Policy Attitudes ◽  
Self Interest ◽  
Close Relationship ◽  
Direction Of Causation ◽  
Complete Account

AbstractRecent research on the sources of individual attitudes toward trade policy comes to very different conclusions about the role of economic self-interest. The skeptical view suggests that long-standing symbolic predispositions and sociotropic perceptions shape trade policy opinions more than one's own material well-being. We believe this conclusion is premature for two reasons. First, the practice of using one attitude to predict another raises questions about direction of causation that cannot be answered with the data at hand. This problem is most obvious when questions about the expected impact of trade are used to predict opinions about trade policy. Second, the understanding of self-interest employed in most studies of trade policy attitudes is unrealistically narrow. In reality, the close relationship between individual economic interests and the interests of the groups in which individuals are embedded creates indirect pathways through which one's position in the economy can shape individual trade policy preferences. We use the data employed by Mansfield and Mutz to support our argument that a more complete account of trade attitude formation is needed and that in such an account economic interests may yet play an important role.1

STUDIES ON THE MECHANISM OF DECIDUALIZATION. V.

1963 ◽  
Vol 43 (3) ◽  
pp. 462-468 ◽  
Author(s):  
M. C. Shelesnyak ◽  
Liliane Tic
Keyword(s):  
Nucleic Acids ◽  
Metabolic Activity ◽  
Vaginal Smear ◽  
Uterine Weight ◽  
Close Relationship

ABSTRACT The uteri of pseudopregnant rats show a peak of metabolic activity on the 4th and 5th day of leucocytic smear. After the administration of 20 mg of pyrathiazine Cl on the 4th day of pseudopregnancy (L4) in order to induce decidualization of the progestational endometrium, the metabolic activity of the uterus becomes intensified. The amount of synthesis, estimated by determinations of uterine weight, and amount of protein and nucleic acids, was considered as being related to an oestrogen surge occurring on the 3rd day. The present work was undertaken to confirm the relation between the oestrogen surge and the metabolic activity found in the uterus thereafter by using an antioestrogenic substance: ethanoxytriphetol (MER-25). The experiments were performed in pseudopregnant as well as in decidualizing animals. MER-25 was injected on the 3rd day of leucocytic vaginal smear of pseudopregnancy. Analyses of the uterine components 24, 48, 72, 96 h after the injection of the antioestrogen showed a definite inhibition of the synthetic processes in the uterus of the otherwise untreated pseudopregnant rat as well as in decidualizing uterus. The results, confirm the role of oestrogen surge in the processes of decidualization and the close relationship between the oestrogen surge, increase of metabolism and decidualization.

Gender, Memory, and Identity in the Roman World

2019 ◽  
Keyword(s):  
Roman Empire ◽  
Late Antiquity ◽  
Roman History ◽  
Public And Private ◽  
Imperial Rome ◽  
The Past ◽  
Roman World ◽  
Material Sources ◽  
Close Relationship

This volume approaches three key concepts in Roman history — gender, memory and identity — and demonstrates the significance of their interaction in all social levels and during all periods of Imperial Rome. When societies, as well as individuals, form their identities, remembrance and references to the past play a significant role. The aim of Gender, Memory, and Identity in the Roman World is to cast light on the constructing and the maintaining of both public and private identities in the Roman Empire through memory, and to highlight, in particular, the role of gender in that process. While approaching this subject, the contributors to this volume scrutinise both the literature and material sources, pointing out how widespread the close relationship between gender, memory and identity was. A major aim of Gender, Memory, and Identity in the Roman World as a whole is to point out the significance of the interaction between these three concepts in both the upper and lower levels of Roman society, and how it remained an important question through the period from Augustus right into Late Antiquity.

scholarly journals P01.01 The role of exosome miRNA between tumor cells and microglias during the progression of medulloblastoma

2019 ◽  
Vol 21 (Supplement_3) ◽  
pp. iii24-iii24
Author(s):  
Q Chang ◽  
L Zhu ◽  
N Li
Keyword(s):  
Tumor Cells ◽  
Critical Role ◽  
Expression Level ◽  
Migration And Invasion ◽  
Specific Marker ◽  
Migration Ability ◽  
Daoy Cell ◽  
Bv2 Cells ◽  
Close Relationship

Abstract BACKGROUND Medulloblastoma (MB) is the most common malignant paediatric brain tumor. Recent studies show that M2 cells were relative more abundant in Shh subtype of MBs compared with other three subtypes. It’s known that M2 cells have close relationship with many tumors’ progression. But if they play any role in the progression of Shh subtype of MB is not yet clear. Many studies demonstrate that exosomes carring miRNAs have close relationship with tumor invasion. The aim of present study is to clarify the role of exosome miRNA between tumor cells and microglias during the progression of Shh subtype of medulloblastoma. MATERIAL AND METHODS Immunofluerescence staining using iNOS and Arg1, which is M1 and M2 specific marker, respectively, was performed in four subtypes of MBs. After coculture of exosomes extracted from Shh subtype of MB cell (DAOY) with microglia cell (BV2), Q-PCR and ELISA assay were done to evaluate the polarization status of the microglia. Transwell and scratch assay were then performed to detect the migration ability of DAOY cell after treatment of exosomes from polirized M2 cells. MiRNA sequencing by Ion Proton technology was then done to analyze the miRNAs expression level between Shh subtype and other subtype of MBs. Transformation assay was used to overexpress and inhibit the expression of these miRNAs respectively to further clarify the role of exosome miRNA in the polarization of BV2 cells. RESULTS M2 cells were observed more abundant than other three subtypes of tumors, supporting that M2 cells play some role in this subtype of MBs. Exosomes of DAOY cells can induce the polarization of M2 cells. The polarized M2 cells can improved the migration and invasion ability of DAOY cell. Dozens of miRNAs were identified with different expression level between Shh subtype of MBs and other subtype of MB cells. Among them, 4 miRNAs were reported to be related with polariztion of M2 in many other lesions. Three of the 4 miRNAs can induce the polarization of M2 in present study. CONCLUSION Our study demonstrated exosome miRNA play a critical role between tumor cells and microglias during the progression of Shh subtype of medulloblastoma.

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