scholarly journals Transcriptomics Integrated with Metabolomics Reveals the Effect of Cluster Thinning on Monoterpene Biosynthesis in ‘Muscat Hamburg’ Grape

Foods ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2718
Author(s):  
Xiaofeng Yue ◽  
Yanlun Ju ◽  
Yulin Fang ◽  
Zhenwen Zhang
Keyword(s):  
Network Analysis ◽  
Molecular Basis ◽  
Developmental Stages ◽  
Targeted Metabolomics ◽  
Grape Quality ◽  
Cluster Thinning ◽  
Gene Correlation ◽  
Monoterpene Biosynthesis ◽  
Monoterpene Metabolism ◽  
The Relationship

Monoterpenes are crucial to floral and fruit aromas in grapes and wines. Cluster thinning is a common practice for improving grape quality. Using Vitis vinifera cv. Muscat Hamburg, the effects of three cluster-thinning regimes on the biosynthesis and accumulation of monoterpenes from véraison to harvest were investigated at the transcriptomics and targeted metabolomics levels. It was observed that more intense thinning produced higher concentrations of total monoterpenes, particularly in their bound forms. The numbers of differentially expressed genes among the three treatments were 193, 200, and 238 at the three developmental stages. In total, 10 modules were identified from a weighted gene correlation network analysis, and one module including 492 unigenes was associated with monoterpene metabolism. These findings provide new insights into the molecular basis of the relationship between cluster thinning and monoterpene biosynthesis in Muscat Hamburg grape. Cluster thinning could be carefully considered for its application in production.

scholarly journals Review article: Jesus’ resurrection in Joseph’s garden

2010 ◽  
Vol 66 (1) ◽  
Author(s):  
Estelle Dannhauser
Keyword(s):  
Developmental Stages ◽  
Faith Community ◽  
Review Article ◽  
Historical Jesus ◽  
Life And Death ◽  
The Relationship ◽  
Community Church

The article is a lengthy review of the book Jesus’ resurrection in Joseph’s garden by P.J.W. (Flip) Schutte. The book represents a quest to trace the relationship between Jesus’ resurrection, myth and canon. Schutte finds the origin of events underlying the biblical canon in proclamation. His focus in the book is the proclamation of the death and resurrection of Christ, which, in its developmental stages, hinged on the life and death of the historical Jesus. Proclamation developed into a mythical narrative that became the foundational myth for the Christ cult, validating its existence and rituals. With the growth and institutionalisation of the faith community (church), came an increased production of literature, causing the power-wielding orthodoxy to identify a body of literature containing the ‘truth’ and ‘correct teaching’, thus establishing the authoritative canon. In, through, behind and beyond Jesus of Nazareth, Schutte has perceived a canon behind the canon: a God of love. In Jesus, the man of myth with historical roots who has become to us the observable face of God, Schutte confesses the kerygma to open up before him. The proclamation therefore extends an invitation to join in a mythological experience and an encounter with God whose love is preached in the metaphor called Easter.

scholarly journals A Network Analysis of the Relationship among Reading, Spelling and Maths Skills

2021 ◽  
Vol 11 (5) ◽  
pp. 656
Author(s):  
Pierluigi Zoccolotti ◽  
Paola Angelelli ◽  
Chiara Valeria Marinelli ◽  
Daniele Luigi Romano
Keyword(s):  
Network Analysis ◽  
Clinical Analysis ◽  
Skill Learning ◽  
Fifth Grade ◽  
Learning Skills ◽  
Level Model ◽  
Multi Level ◽  
Unselected Group ◽  
The Relationship

Background. Skill learning (e.g., reading, spelling and maths) has been predominantly treated separately in the neuropsychological literature. However, skills (as well as their corresponding deficits), tend to partially overlap. We recently proposed a multi-level model of learning skills (based on the distinction among competence, performance, and acquisition) as a framework to provide a unitary account of these learning skills. In the present study, we examined the performance of an unselected group of third- to fifth-grade children on standard reading, spelling, and maths tasks, and tested the relationships among these skills with a network analysis, i.e., a method particularly suited to analysing relations among different domains. Methods. We administered a battery of reading, spelling, and maths tests to 185 third-, fourth-, and fifth-grade children (103 M, 82 F). Results. The network analysis indicated that the different measures of the same ability (i.e., reading, spelling, and maths) formed separate clusters, in keeping with the idea that they are based on different competences. However, these clusters were also related to each other, so that three nodes were more central in connecting them. In keeping with the multi-level model of learning skills, two of these tests (arithmetic facts subtest and spelling words with ambiguous transcription) relied heavily on the ability to recall specific instances, a factor hypothesised to underlie the co-variation among learning skills. Conclusions. The network analysis indicated both elements of association and of partial independence among learning skills. Interestingly, the study was based on standard clinical instruments, indicating that the multi-level model of learning skills might provide a framework for the clinical analysis of these learning skills.

scholarly journals Network Analysis of the Interaction between Different Religious and Philosophical Movements in Early Judaism

Philosophies ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 2
Author(s):  
Igor R. Tantlevskij ◽  
Ekaterina V. Gromova ◽  
Dmitry Gromov
Keyword(s):  
Social Networks ◽  
Network Analysis ◽  
Second Temple ◽  
Political Movements ◽  
Early Judaism ◽  
Social Balance ◽  
The Relationship

This paper presents an attempt to systematically describe and interpret the evolution of different religious and political movements in Judaea during the period of the Second Temple using the methods of the theory of social networks. We extensively analyzed the relationship between the main Jewish sects: Pharisees, Sadducees, Essenes (Qumranites), and later also Zealots. It is shown that the evolution of the relations between these sects agreed with the theory of social balance and their relations evolved toward more socially balanced structures.

Exploring the Relationship Between Social Interaction, Cognitive Processing and Learning Achievements in a MOOC Discussion Forum

2021 ◽  
pp. 073563312110273
Author(s):  
Zhi Liu ◽  
Ning Zhang ◽  
Xian Peng ◽  
Sannyuya Liu ◽  
Zongkai Yang ◽  
...  
Keyword(s):  
Social Network ◽  
Social Interaction ◽  
Network Analysis ◽  
Cognitive Processing ◽  
Learning Analytics ◽  
Discussion Forum ◽  
Community Type ◽  
Eigenvector Centrality ◽  
Community Types ◽  
The Relationship

In the field of learning analytics, mining the regularities of social interaction and cognitive processing have drawn increasing attention. Nevertheless, in MOOCs, there is a lack of investigations on the combination of social and cognitive behavioral patterns. To fill in this gap, this study aimed to uncover the relationship between social interaction, cognitive processing, and learning achievements in a MOOC discussion forum. Specifically, we collected the 3925 participants’ forum data throughout 16 weeks. Social network analysis and epistemic network analysis were jointly adopted to investigate differences in social interaction, cognitive processing between two achievement groups, and the differences in cognitive processing networks between two types of communities. Finally, moderation analysis was employed to examine the moderating effect of community types between cognitive processing and learning achievements. Results indicated that: (1) the high- and low-achieving groups presented significant differences in terms of degree, betweenness, and eigenvector centrality; (2) the stronger cognitive connections were found within the high-achieving group and the instructor-led community; (3) the cognitive processing indicators including insight, discrepancy, and tentative were significantly negative predictors of learning achievements, whereas inhibition and exclusive were significantly positive predictors; (4) the community type moderated the relationship between cognitive processing and learning achievements.

Metabolism-driven post-translational modifications of H3K9 in early bovine embryos

Reproduction ◽  
2021 ◽  
Vol 162 (3) ◽  
pp. 181-191
Author(s):  
Jessica Ispada ◽  
Aldcejam Martins da Fonseca Junior ◽  
Otávio Luiz Ramos Santos ◽  
Camila Bruna de Lima ◽  
Erika Cristina dos Santos ◽  
...  
Keyword(s):  
Metabolic Pathways ◽  
Developmental Stages ◽  
De Novo ◽  
Blastocyst Stage ◽  
Developmental Model ◽  
Bovine Embryos ◽  
Acetyl Coa ◽  
Post Translational Modifications ◽  
The Relationship ◽  
Different Levels

Metabolic and molecular profiles were reported as different for bovine embryos with distinct kinetics during the first cleavages. In this study, we used this same developmental model (fast vs slow) to determine if the relationship between metabolism and developmental kinetics affects the levels of acetylation or tri-methylation at histone H3 lysine 9 (H3K9ac and H3K9me3, respectively). Fast and slow developing embryos presented different levels of H3K9ac and H3K9me3 from the earliest stages of development (40 and 96 hpi) and up to the blastocyst stage. For H3K9me3, both groups of embryos presented a wave of demethylation and de novo methylation, although it was more pronounced in fast than slow embryos, resulting in blastocysts with higher levels of this mark. The H3K9ac reprogramming profile was distinct between kinetics groups. While slow embryos presented a wave of deacetylation, followed by an increase in this mark at the blastocyst stage, fast embryos reduced this mark throughout all the developmental stages studied. H3K9me3 differences corresponded to writer and eraser transcript levels, while H3K9ac patterns were explained by metabolism-related gene expression. To verify if metabolic differences could alter levels of H3K9ac, embryos were cultured with sodium-iodoacetate (IA) or dichloroacetate (DCA) to disrupt the glycolytic pathway or increase acetyl-CoA production, respectively. IA reduced H3K9ac while DCA increased H3K9ac in blastocysts. Concluding, H3K9me3 and H3K9ac patterns differ between embryos with different kinetics, the second one explained by metabolic pathways involved in acetyl-CoA production. So far, this is the first study demonstrating a relationship between metabolic differences and histone post-translational modifications in bovine embryos.

Rhythmic changes in the serotonin content of the brain and eyestalk of crayfish during development

1999 ◽  
Vol 202 (20) ◽  
pp. 2823-2830 ◽  
Author(s):  
O. Castanon-Cervantes ◽  
B. Battelle ◽  
M.L. Fanjul-Moles
Keyword(s):  
Developmental Stages ◽  
Procambarus Clarkii ◽  
Cerebral Ganglion ◽  
Reversed Phase ◽  
Circadian Variations ◽  
Constant Illumination ◽  
Serotonin Content ◽  
Dim Light ◽  
The Relationship ◽  
The Brain

The present study investigated developmental circadian changes in the content of 5-hydroxytryptamine (5-HT) in two structures proposed to contain pacemakers in crayfish Procambarus clarkii: the cerebral ganglion and the eyestalks. Crayfish (N=260) from three developmental stages were divided into two groups: (1) animals subjected to 12 h:12 h light:dark cycles for 10 days and (2) animals treated as described above, then exposed to 72 h of continuous dim light. Crayfish from both groups were killed at different times of day, and the cerebral ganglion and the eyestalks of each were assayed for 5-HT by reversed-phase HPLC with electrochemical detection. In all stages of development, 5-HT content (expressed as (μ)g g(−)(1)wet mass tissue) showed circadian variations in both structures analyzed; rhythms continued to free-run under constant illumination, and total 5-HT content was higher in the brain (0.581+/−0.36 (μ)g g(−)(1); mean +/− s.e.m.) than in the eyestalks (0.299+/−0.15 (μ)g g(−)(1)). As development advances, the percentage of the rhythm that shows periods of 24 h diminishes, while the percentage of the rhythm that shows periods of 9 to 12 h increases. This seems to indicate that pulsatile variations in 5-HT content are superimposed in a circadian component. The relationship between the 5-HT rhythm and electroretinogram and motor activity rhythms during development is discussed.

scholarly journals Biochemical and agronomical responses of grapevines to alteration of source-sink ratio by cluster thinning and shoot trimming

Bragantia ◽  
2010 ◽  
Vol 69 (1) ◽  
pp. 17-25 ◽  
Author(s):  
Renata Vieira da Mota ◽  
Claudia Rita de Souza ◽  
Camila Pinheiro Carvalho Silva ◽  
Gustavo de Faria Freitas ◽  
Tânia Misuzu Shiga ◽  
...  
Keyword(s):  
Sugar Metabolism ◽  
Minas Gerais ◽  
Cabernet Sauvignon ◽  
Color Intensity ◽  
Fruit Removal ◽  
Grape Quality ◽  
Minas Gerais State ◽  
Cluster Thinning ◽  
Source Sink ◽  
Berry Set

The control of leaf to fruit ratio by the practice of entire clusters removal from the vine upon berry set has been used in traditional vineyards in order to regulate yield and to improve chemical composition of the berries. Although this practice has been settled in temperate zones, little is known about grapevines behavior in tropical growing areas. The aim of this work was to evaluate the biochemical and agronomical responses of two Vitis vinifera cultivars (Merlot and Cabernet Sauvignon) grown in Caldas, Minas Gerais, Brazil, a new winegrape region. Grapevines were submitted to cluster thinning (0%, 50% and 75% of cluster removal) and trimming treatments (trimmed and untrimmed) imposed at pea size stage. The source-sink alteration by fruit removal and shoot trimming had impact on yield, leaf sugar metabolism and grape composition. Although there was an improvement in color intensity of the berries with reduction of fruit load, the cluster thinning practice should be avoided in vineyards grown in the south of Minas Gerais State without impairment of wine grape quality. On the other hand, shoot trimming practice should be recommended only for Merlot in order to improve sugar grapes from vines with no cluster removal.

scholarly journals Can You Identify These Celebrities? A Network Analysis on Differences between Word and Face Recognition

Mathematics ◽  
2020 ◽  
Vol 8 (5) ◽  
pp. 699 ◽  
Author(s):  
Carmen Moret-Tatay ◽  
Inmaculada Baixauli-Fortea ◽  
M. Dolores Grau Sevilla ◽  
Tatiana Quarti Irigaray
Keyword(s):  
Face Recognition ◽  
Network Analysis ◽  
Word Processing ◽  
Processing System ◽  
Place Of Origin ◽  
Masked Repetition ◽  
The Relationship ◽  
Repetition Priming Effect ◽  
Vast Range

Face recognition is located in the fusiform gyrus, which is also related to other tasks such word recognition. Although these two processes have several similarities, there are remarkable differences that include a vast range of approaches, which results from different groups of participants. This research aims to examine how the word-processing system processes faces at different moments and vice versa. Two experiments were carried out. Experiment 1 allowed us to examine the classical discrimination task, while Experiment 2 allowed us to examine very early moments of discrimination. In the first experiment, 20 Spanish University students volunteered to participate. Secondly, a sample of 60 participants from different nationalities volunteered to take part in Experiment 2. Furthermore, the role of sex and place of origin were considered in Experiment 1. No differences between men and women were found in Experiment 1, nor between conditions. However, Experiment 2 depicted shorter latencies for faces than word names, as well as a higher masked repetition priming effect for word identities and word names preceded by faces. Emerging methodologies in the field might help us to better understand the relationship among these two processes. For this reason, a network analysis approach was carried out, depicting sub-communities of nodes related to face or word name recognition, which were replicated across different groups of participants. Bootstrap inferences are proposed to account for variability in estimating the probabilities in the current samples. This supports that both processes are related to early moments of recognition, and rather than being independent, they might be bilaterally distributed with some expert specializations or preferences.

scholarly journals Seasonal maturation of Glypthelmins vitellinophilum (Trematoda: Digenea) in Lysapsus limellus (Anura: Pseudidae) from an Argentinian subtropical permanent pond

2006 ◽  
Vol 66 (1a) ◽  
pp. 85-93 ◽  
Author(s):  
M. I. Hamann
Keyword(s):  
Body Length ◽  
Developmental Stages ◽  
Small Body ◽  
Stage Iv ◽  
The Body ◽  
Climatic Fluctuations ◽  
Parasite Stage ◽  
Permanent Pond ◽  
Body Sizes ◽  
The Relationship

From December 1995 to November 2000, the seasonal maturation of Glypthelmins vitellinophilum Dobbin, 1958, in its definitive host, the frog Lysapsus limellus Cope, 1862, was studied in a subtropical permanent pond in northeastern Argentina. The objectives of this study were: 1) to determine the infrapopulation dynamics of the parasite, analyzing the seasonal maturation cycle throughout the years; and 2) to examine the relationship between the intensity of trematode infection in different developmental stages (recruitment, growth and maturation) and the host's body length. Of a total of 1,400 frogs examined over 60 months (5 years), 38% were found to be infected with G. vitellinophilum, and the intensity of infection was 1-15 trematodes per frog. Specimens of G. vitellinophilum were present in L. limellus throughout the years, but did not show a pronounced seasonal maturation cycle. Possible reasons for these findings are discussed with reference to climatic fluctuations and biotic factors. The infective period of the parasite (stage I) occurred in summer, autumn and spring, coinciding with the time each frog cohort appeared. These infections were found principally in small body sizes (classes 1 and 2) of L. limellus. Juvenile and nongravid specimens of worms (stage II and III) were found in frogs of different body sizes throughout the period of investigation. Gravid specimens of the parasite (stage IV) were generally recorded in autumn, winter and spring, mainly in the bodies of larger frogs. The body length of Trematodes in stages I and IV was significantly and positively correlated with that of the frogs.

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