scholarly journals Secular Trends in Lipid Profiles in Korean Adults Based on the 2005–2015 KNHANES

2019 ◽  
Vol 16 (14) ◽  
pp. 2555 ◽  
Author(s):  
Yu-Jin Kwon ◽  
Jae-Woo Lee ◽  
Hee-Taik Kang
Keyword(s):  
Age Groups ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Lipid Lowering ◽  
Men And Women ◽  
Korean Adults ◽  
Health And Nutrition ◽  
Specific Analysis ◽  
Lowering Drug ◽  
Policies And Programs

Dyslipidemia is a primary, critical risk factor for cardiovascular disease. Therefore, evaluating the trends in lipid profiles is crucial for the development of health policies and programs. We studied trends in lipid profiles in Korean adults over an 11-year period according to the use of lipid-lowering medications through age-specific analysis. A total of 73,890 participants were included in the Korean National Health and Nutrition Examination Survey III (2005)-VI (2013–2015). The proportion of participants on lipid-lowering medications has increased. This trend was apparent in age groups of over 40 years in both men and women. Lipid-lowering medications successfully reduced mean total cholesterol (TC), but there was no favorable trend in TC in participants not taking lipid-lowering medication in both men and women. Unlike men, triglyceride and non-high-density lipoprotein cholesterol (HDL) decreased in women without lipid-lowering medications. In age-specific hypercholesterolemia, the prevalence of hypercholesterolemia significantly increased in the age groups of 30–59 and 30–49 years in men and women without lipid-lowering medications, respectively. Meanwhile, mean HDL-C levels increased over the 11-year period regardless of lipid-lowering drug use in both men and women. These analyses identified an upward trend in TC and HDL-C over the 11-year period.

Abstract 17147: No Changes in Average Lipid Profiles in the United States From 2003 to 2012: The National Health and Nutrition Examination Survey 2003-2012

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Peter P Toth ◽  
Michael K Palmer ◽  
Karin M Henriksson
Keyword(s):  
High Risk ◽  
National Health ◽  
Risk Group ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Lipoprotein Cholesterol ◽  
Nutrition Examination Survey ◽  
Men And Women ◽  
Health And Nutrition ◽  
The Us

Introduction: Lipid-lowering therapies (LLT) are now regularly used in the management of dyslipidemia, but it is not known how the increased use of LLT has influenced lipid levels of the US population. We determined the average lipid profiles of the US population from 2003-2012 in the National Health and Nutrition Examination Survey (NHANES). Methods: Coronary heart disease risk using NCEP ATP III criteria was assessed in adult participants in 2-yearly NHANES surveys from 2003-2004 to 2011-2012. Fasting serum values were used to determine lipid profiles of men and women in each risk group. The proportion of participants in each risk group receiving LLT was also calculated. Results: Estimates for the US population were based on 11,256 observations in NHANES from 2003-2012. From the 2003-2004 survey to the 2011-2012 survey, a significant increase in the use of LLT was observed in the low- (6% to 11%; p<0.0001) and high-risk (41% to 52%; p=0.008) groups. A possible trend for reduction in median triglyceride (TG) levels was observed in women in the high-risk group only, from 170 mg/dL (2003-2004) to 127 mg/dL (2011-2012). However, sample sizes are small (165-248 participants), and variability is high; therefore, this may impact on the applicability of the TG results. For both men and women and in all risk categories, no obvious trend for change in mean levels of non-high-density lipoprotein cholesterol (non-HDL-C), low-density lipoprotein cholesterol (LDL-C), and HDL-C was observed (Figure). Mean HDL-C levels were higher in women than in men in all risk groups, consistently over the time period (Figure). Conclusion: Despite an increase in the use of LLT, we observed no trend for change in lipid profiles in low-, intermediate- or high-risk men and women in the US population. This may be due to the variability in response to LLT, and highlights the need for more aggressive identification and treatment of high-risk individuals, as recommended in the ACC/AHA guideline.

scholarly journals Prevalence, awareness, treatment, and control of dyslipidemia among diabetes mellitus patients and predictors of optimal dyslipidemia control: results from the Korea National Health and Nutrition Examination Survey

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Seung Jae Kim ◽  
Oh. Deog Kwon ◽  
Kyung-Soo Kim
Keyword(s):  
Diabetes Mellitus ◽  
Optimal Control ◽  
National Health ◽  
Age Groups ◽  
Density Lipoprotein ◽  
Nutrition Examination Survey ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Factors Influencing ◽  
And Control

Abstract Background This study aimed to investigate the prevalence, awareness, treatment, and control rates of dyslipidemia and identify the predictors of optimal control (low-density lipoprotein cholesterol < 100 mg/dL) among patients with diabetes mellitus (DM). Methods A cross-sectional study was conducted using the representative Korea National Health and Nutrition Examination Survey (2014–2018). Overall, 4311 patients with DM, aged ≥19 years, and without cardiovascular diseases were selected, and the prevalence, awareness, treatment, and control rates of dyslipidemia were calculated. Univariate and multivariate logistic regression analyses were conducted to evaluate the factors influencing the optimal control of dyslipidemia. Results Dyslipidemia was prevalent in 83.3% of patients with DM, but the awareness and treatment rates were 36.5 and 26.9%, respectively. The control rate among all patients with dyslipidemia was 18.8%, whereas it was 61.1% among those being treated. Prevalence and awareness rates were also significantly higher in women than in men. Dyslipidemia was most prevalent in those aged 19–39 years, but the rates of awareness, treatment, and control among all patients with dyslipidemia in this age group were significantly lower than those in other age groups. The predictors of optimal control were age ≥ 40 years [range 40–49 years: adjusted odds ratio (aOR) 3.73, 95% confidence interval (CI) 1.43–9.72; 50–59 years: aOR 6.25, 95% CI 2.50–15.65; 60–69 years: aOR 6.96, 95% CI 2.77–17.44; 70–79 years: aOR 9.21, 95% CI 3.58–23.74; and ≥ 80 years: aOR 4.43, 95% CI 1.60–12.27]; urban living (aOR 1.44, 95% CI 1.15–1.80); higher body mass index (aOR 1.27, 95% CI 1.13–1.42); lower glycated hemoglobin levels (aOR 0.71, 95% CI 0.67–0.76); hypertension (aOR 1.53, 95% CI 1.22–1.92); poorer self-rated health status (aOR 0.72, 95% CI 0.62–0.84); and receiving regular health check-ups (aOR 1.58, 95% CI 1.25–2.00). Conclusions Most patients with DM were diagnosed with dyslipidemia, but many were unaware of or untreated for their condition. Therefore, their control rate was suboptimal. Thus, by understanding factors influencing optimal control of dyslipidemia, physicians should make more effort to encourage patients to undergo treatment and thus, adequately control their dyslipidemia.

scholarly journals Cardiovascular risk according to plasma apolipoprotein and lipid profiles in a Canadian First Nation

2010 ◽  
Vol 31 (1) ◽  
pp. 33-38 ◽  
Author(s):  
ND Riediger ◽  
SG Bruce ◽  
TK Young
Keyword(s):  
Cardiovascular Risk ◽  
First Nations ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Age Groups ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Apolipoprotein A1 ◽  
First Nation ◽  
Future Research

Introduction Despite high diabetes rates among Canadian First Nations people, little is known about their cardiovascular disease risk. Our aim was to describe the apolipoprotein profile with respect to cardiovascular risk in a Canadian First Nation community. Methods In 2003, a representative sample of adult members of a Manitoba First Nation (N = 483) participated in a screening study for diabetes and diabetes complications. We assessed their cardiovascular risk factors. Results Sixty percent of women were at increased cardiovascular risk because of low apolipoprotein A1 (apoA1) levels, compared with 35% of men. The proportion of women with low apoA1 levels decreased with age, but the proportion with low high-density lipoprotein levels remained stable across age groups. Both apoB and apoA1 were significantly associated with obesity when age, sex, diastolic blood pressure, homocysteine, diabetes, and insulin resistance were controlled for. Conclusion Apolipoprotein and lipid profiles in this First Nation population suggest high cardiovascular risk. Future research should characterize the lipoprotein particle size in this population.

scholarly journals Gender Dictates the Relationship between Serum Lipids and Leukocyte Counts in the National Health and Nutrition Examination Survey 1999–2004

2019 ◽  
Vol 8 (3) ◽  
pp. 365 ◽  
Author(s):  
Catherine Andersen ◽  
Terrence Vance
Keyword(s):  
Total Cholesterol ◽  
National Health ◽  
Blood Lymphocyte ◽  
Serum Lipids ◽  
Lipid Lowering ◽  
Nutrition Examination Survey ◽  
Men And Women ◽  
Health And Nutrition ◽  
Leukocyte Counts ◽  
The Relationship

Dyslipidemias and leukocytosis are associated with cardiovascular disease and immune disorders. Mechanistic studies have shown lipoprotein metabolism to play a significant role in the regulation of atherosclerosis development and leukocyte activation, whereas lipid-lowering treatments have been shown to exert beneficial anti-inflammatory and immunomodulatory effects in clinical trials. However, the relationship between clinical markers of lipid metabolism and leukocyte counts has not been extensively evaluated at the population level. We aimed to determine whether clinical blood lipid measures are associated with leukocyte counts in the general U.S. population represented in the National Health and Nutrition Examination Survey (NHANES) 1999–2004, and whether differences exist between men and women (n = 5647). We observed a strong positive linear trend between serum triglycerides vs. blood lymphocyte and basophil counts in both men and women, whereas a positive trend between monocytes vs. triglycerides and lymphocytes vs. total cholesterol and LDL-cholesterol (LDL-C) was only detected in women. Conversely, HDL-C was inversely associated with a greater number of leukocyte subsets in men, whereas inverse trends between HDL-C vs. lymphocytes were observed in both men and women. In multiple regression models, a 10% increase in total cholesterol, LDL-C, and triglycerides was associated with a predicted 1.6%, 0.6%, and 1.4% increase in blood lymphocyte counts in women, respectively, whereas no relationship was observed in men. In both men and women, a 10% increase in triglycerides was additionally associated with higher lymphocyte, neutrophil, and basophil counts, whereas 10% increases in HDL-cholesterol were associated with significantly lower lymphocyte, neutrophil, eosinophil, and basophil counts in men, in addition to lower lymphocyte and monocyte counts in women. These findings suggest that clinical lipid markers may be used to predict blood leukocyte distributions, and that a gender-specific relationship exists between distinct classes of serum lipids and immune cell subsets.

scholarly journals Trends in Fermented Food Consumption and Sodium Intake from Fermented Foods for Korean Adults Using the Korea National Health and Nutrition Examination Survey (KNHANES) (P18-025-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Sangyoung Kim ◽  
Jeanne Freeland-Graves ◽  
Hyun Ja Kim
Keyword(s):  
Food Consumption ◽  
National Health ◽  
Sodium Intake ◽  
Fermented Food ◽  
Fermented Foods ◽  
Nutrition Examination Survey ◽  
Men And Women ◽  
Korean Adults ◽  
Health And Nutrition ◽  
Over Time

Abstract Objectives To examine the trends in the consumption of fermented foods and sodium intake over time, using data from the Korean National Health and Nutrition Examination Survey (KNHANES). Methods This research study is a secondary analysis using KNHANES data from 1998 to 2016 which is a cross-sectional survey. The target population was Korean adults, ages ≥19 years and the total number was 76,199, with 32,324 men and 43,875 women. Assessment of fermented food consumption and sodium intake was conducted via analysis of 24-hour dietary recall data. Multivariate linear regressions and logistic regressions were performed to calculate the P for trends by applying strata, cluster, and sampling weights by SAS PROC SURVEY. Age was standardized for all analyses in order to calculate P for trends for education, income, fermented food consumption, and sodium intake. Results A significant decline in fermented food consumption was observed in both men and women (P < 0.0001). Among fermented foods, kimchi consumption was greatly reduced while pickled vegetables consumption showed a marked increase. Similarly, sodium intake from fermented foods significantly declined over time in both men and women (P < 0.0001). Conclusions The consumption of fermented foods and sodium intake from fermented foods by Korean adults significantly decreased over time from 1998 to 2016. Funding Sources N/A.

Secondary prevention care and effect: Total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction – The Tromsø Study 1994–2016

2018 ◽  
Vol 17 (6) ◽  
pp. 563-570 ◽  
Author(s):  
Laila A Hopstock ◽  
Anne Elise Eggen ◽  
Maja-Lisa Løchen ◽  
Ellisiv B Mathiesen ◽  
Inger Njølstad ◽  
...  
Keyword(s):  
Ldl Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipid Lowering ◽  
Low Density ◽  
Lipid Levels ◽  
Treatment Target ◽  
Cholesterol Levels ◽  
Lipid Lowering Drug ◽  
Lowering Drug

Background: Secondary prevention guidelines after myocardial infarction (MI) are gender neutral, but underutilisation of treatment in women has been reported. Design: We investigated the change in total and low-density lipoprotein (LDL) cholesterol levels and lipid-lowering drug (LLD) use after first-ever MI in a population-based study. Methods: We followed 10,005 participants (54% women) attending the Tromsø Study 1994–1995 and 8483 participants (55% women) attending the Tromsø Study 2007–2008 for first-ever MI up to their participation in 2007–2008 and 2015–2016, respectively. We used linear and logistic regression models to investigate sex differences in change in lipid levels. Results: A total of 395 (MI cohort I) and 132 participants (MI cohort II) had a first-ever MI during 1994–2008 and 2007–2013, respectively. Mean change in total cholesterol was −2.34 mmol/L (SD 1.15) in MI cohort I, and in LDL cholesterol was −1.63 mmol/L (SD 1.12) in MI cohort II. Men had a larger decrease in lipid levels compared to women: the linear regression coefficient for change was −0.33 (95% confidence interval [CI] −0.51 to −0.14) for total cholesterol and −0.21 (95% CI −0.37 to −0.04) for LDL cholesterol, adjusted for baseline lipid value, age and cohort. Men had 73% higher odds (95% CI 1.15−2.61) of treatment target achievement compared to women, adjusted for baseline lipid value, age and cohort. LLD use was reported in 85% of women and 92% of men in MI cohort I, and 80% in women and 89% in men in MI cohort II. Conclusions: Compared to men, women had significantly less decrease in lipid levels after MI, and a smaller proportion of women achieved the treatment target.

scholarly journals Vegetable intake in Korea: data from the Korean National Health and Nutrition Examination Survey 1998, 2001 and 2005

2010 ◽  
Vol 103 (10) ◽  
pp. 1499-1506 ◽  
Author(s):  
Jung-Sug Lee ◽  
Jeongseon Kim
Keyword(s):  
National Health ◽  
Vegetable Intake ◽  
Vegetable Consumption ◽  
Age Groups ◽  
Population Based ◽  
Age Group ◽  
Nutrition Examination Survey ◽  
Men And Women ◽  
Consumption Ratio ◽  
Health And Nutrition

The purpose of the present study was to analyse vegetable intake by the Korean population based on different meal formats. Twenty-four-hour dietary recall data from the Korean National Health and Nutrition Examination Survey were used to assess daily vegetable intake and consumption ratio of vegetables for different meal types/dining locations. Analysis was stratified by sex and age group. Daily vegetable intake increased from 293·5 g in 1998 to 305·7 g in 2001 and to 335·9 g in 2005. Findings were similar in men and women, as well as in each age group. Analyses for each meal type revealed that vegetable intake during breakfast did not substantially change, but vegetable intake increased during lunch and dinner. While vegetable consumption ratio during breakfast decreased, it increased during lunch and snack time. Men and women showed similar change in the analysis for meal types and dining locations. There were some differences between the age groups in daily vegetable intake depending on the meal type. Another notable observation was the increasing change of vegetable intake during lunch and during meals eaten at cafeterias and restaurants in all the age groups. Analysis of vegetable consumption ratio showed an increased consumption in cafeterias, restaurants, and other places and decreased vegetable intake at home for those aged 16–64 years with time. Since this change may be related to improvements in socioeconomic status, it will be necessary to further investigate difference in vegetable intake based on socioeconomic levels within the population.

scholarly journals Effect of Cholecystectomy on Serum Lipids and Blood Glucose (Hospital Based Observational Prospective Study)

2021 ◽  
Vol 6 (1) ◽  
pp. 8-13
Author(s):  
Om Karki ◽  
Bishow Deep Timilsina
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Lipid Profile ◽  
Glucose Level ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Atherogenic Index ◽  
Lipid Lowering ◽  
Lowering Drug

Introduction: Association between cholelithiasis and dyslipidemia has been shown in many studies. Recent studies have shown improvement in lipid profile following cholecystectomy. This study aimed to determine the changes in lipid profile and blood glucose level after cholecystectomy.Methods: Seventy-three patients of cholelithiasis were studied prospectively. Total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), atherogenic index (AI) and fasting blood sugar (FBS) levels were estimated pre-operatively. Further, the same parameters were studied after cholecystectomy after one week and one-month intervals. None of the patients received any lipid-lowering drug or dietary restriction. Results were analysed and compared.Results: Of the 73 patients with cholelithiasis, 66% were female and 34% male. The mean age of patients was 40.53± 13.16 years. 56% of patients with cholelithiasis had a deranged lipid profile. TC was significantly decreased at one week (p=0.002) and one month (p=0.00) interval after cholecystectomy while TG levels also decreased significantly at one month postoperative (p=0.001). There were no significant differences in LDL-c however improvement was seen on HDL-c. Blood glucose level also increased significantly (p=0.028) after one month of cholecystectomy.Conclusion: Cholelithiasis is associated with an abnormal lipid profile. Cholecystectomy leads to a significant decrease in some of the parameters of lipid profile and the atherogenic index. The presence of gall stones thus should be perceived in the context of metabolic syndrome, which may be investigated and treated.

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