scholarly journals Health Risk Assessment and Source Apportionment of Mercury, Lead, Cadmium, Selenium, and Manganese in Japanese Women: An Adjunct Study to the Japan Environment and Children’s Study

Author(s):  
Chaochen Ma ◽  
Miyuki Iwai-Shimada ◽  
Nozomi Tatsuta ◽  
Kunihiko Nakai ◽  
Tomohiko Isobe ◽  
...  

Toxic element pollution is a serious global health concern that has been attracting considerable research. In this study, we elucidated the major routes of exposure to three toxic elements (mercury, cadmium, and lead) and two essential elements (manganese and selenium) through diet, soil, house dust, and indoor air and assessed the potential health risks from these elements on women from the coastal area of Miyagi prefecture, Japan. Twenty-four-hour duplicate diet, house dust, soil, and indoor air samples were collected from 37 participants. Cd, Pb, Mn, and Se concentrations were measured using inductively coupled plasma mass spectrometry, and Hg concentrations using cold vapor atomic absorption spectrometry. We found that soil and house dust were the primary reservoirs of these elements. Diet contributed most strongly to the daily intake of these elements, with mean values of 0.72, 0.25, 0.054, 47, and 0.94 μg/kg/day for Hg, Cd, Pb, Mn, and Se, respectively. The mean hazard quotient of Hg was 1.53, indicating a high potential health risk from Hg exposure in daily lives. The intakes of other elements were below the tolerable limits. Future studies with a larger sample size are warranted to confirm our findings.

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
O. C. Ekhator ◽  
N. A. Udowelle ◽  
S. Igbiri ◽  
R. N. Asomugha ◽  
Z. N. Igweze ◽  
...  

Objective. Street-vended foods offer numerous advantages to food security; nevertheless, the safety of street food should be considered. This study has investigated the level of potential toxic metal (Pb, Cd, Hg, Sb, Mn, and Al) contamination among street-vended foods in Benin City and Umunede. Methods. Twenty street food samples were purchased from vendors at bus stops. Metals were analyzed with atomic absorption spectrophotometry. The methods developed by the US EPA were employed to evaluate the potential health risk of toxic metals. Results. The concentrations of the toxic metals in mg/kg were in the range of Pb (0.014–1.37), Cd (0.00–0.00017), Hg (0.00–0.00014), Sb (0.00–0.021), Mn (0.00–0.012), and Al (0.00–0.22). All the toxic metals except Pb were below permissible limit set by WHO, EU, and USEPA. The daily intake, hazard quotient, and hazard index of all toxic metals except for Pb in some street foods were below the tolerable daily intake and threshold value of 1, indicating an insignificant health risk. Total cancer risk was within the priority risk level of 1.0E-04 but higher than the acceptable risk level of 1E-06. Conclusion. Consumption of some of these street foods is of public health concern.


Author(s):  
Afshin Ebrahimi ◽  
Elaheh Karimpoor ◽  
Zahra Godazandehha ◽  
Zahra Heidari ◽  
Maryam Zarean ◽  
...  

Introduction: Exposure to mercury (Hg) by consumption of fish is a recent health concern. So, it is important to evaluate the health risks related to canned fish consumption. The purpose of this study was to investigate the potential health risk based on Hg concentration in people who consumed canned fish with a probabilistic approach in Isfahan City, the central province in Iran. Materials and Methods: In this study, 20 popular brands of canned fish prepared in Iran and other countries were selected and analyzed for Hg concentration with atomic absorption spectrometer. The results were compared with the European Communities and JECFA guidelines. Then, a probabilistic method with Monte-Carlo simulation was used to assessment the Provisional Tolerable Daily Intake (PTDI) and the Hazard Quotient (HQ) for consumers in Isfahan City. Results: The average Hg concentrations in samples were 0.251 ± 0.204 and 0.189 ± 0.152 µg/g in canned fish of Iran and other countries, respectively. The Hg level was found below the guideline limit for European Communities and JECFA. The estimated PTDI was 0.037 µg person/day and HQ was 0.074. Conclusion: The results indicated that canned fish available in the markets of Iran did not have a health risk for adults. Moreover, canned fish consumption has a possible influence on the risk estimate and its risk should be assessed  for vulnerable groups.


Author(s):  
A. I. Yaradua ◽  
A. J. Alhassan ◽  
A. Nasir ◽  
K. I. Matazu ◽  
A. Usman ◽  
...  

This study was conducted to determine the heavy metals concentration in Hibiscus leaves cultivated in Katsina State Nigeria. The objectives were mainly to detect the presence of heavy metals in the cultivated Hibiscus leaves in the study area, compare the concentration of heavy metals in samples in relation to the permissible limits specified by WHO/FAO/USEPA Standards. Samples of cultivated Hibiscus leaves were collected in the year 2017 from the selected area.  Analysis for the concentration of these heavy metals; Cr, Cd, Fe, Ni, Mn, Pb and Zn was conducted by the use of AAS (by Atomic Absorption Spectrophotometry) method. The health risks to the local inhabitants from the consumption of the samples were evaluated based on the Target Hazard Quotient (THQ). The possibility of cancer risks for the adult and children population through intake of carcinogenic heavy metals in the samples was estimated using the Incremental Lifetime Cancer Risk (ILCR). Results from this study shows that with the exception of Pb with mean concentration of (0.508-0.978), the mean concentration (mg/kg) range values of Cr (0.135-0.261), Cd (0.042-0.051), Fe (0.684-0.978) and Zn (1.048-1.208) in the samples were generally lower than the USEPA, WHO/FAO maximum permissive limits. The results have indicated that the estimated daily intake (EDI) of the heavy metals were lower than the tolerable daily intake limit set by the USEPA in both samples and the health risk index (HRI) for all the heavy metals were <1. The target hazard quotient (THQ) for the samples for both the adult and children population was in the decreasing order of Zn>Pb>Fe>Cr>Cd. ILCR for Cd is below the threshold risk limit (>10−5) and ILCR for Pb reached the moderate risk limit (>10−3) in all the studied samples in adults, While in children ILCR for both Pb and Cd in samples from Dabai, Daura, Funtua, Matazu and Zango for all samples have reached the moderate risk limit (>10−3), while the ILCR for Pb in samples from Birchi, Dutsinma, Kafur, Katsina and Malunfashi were beyond the moderate risk level (>10−2). The sampling area trend of risk for developing cancer as a result of consuming the studied samples showed: Funtua > Daura > Dutsinma > Katsina > Malunfashi > Matazu > Zango > Ingawa > Kafur > Dabai > Birchi for both adult and children, cumulative cancer risk (∑ILCR) of all the studied Hibiscus samples have reached the moderate risk limit (>10−3) in adult. While in children with the exception of the sample from Birchi, Dabai and Kafur which are within the moderate cancer risk (>10−3) limit, all other samples were beyond the moderate cancer risk (>10−2) limit. The study suggests that consumption of the studied samples in Katsina state is of public health concern as they may contribute to the population cancer burden. 


Author(s):  
O. A Omotoso

This study was carried out to establish health impacts of some trace elements (Al, As, Ba, Cr, Cu, Fe, Mn, Ni, Pb and Zn) in Asa-river, using Inductively Coupled Plasma-Mass Spectrometer technique for the chemical analysis. Laboratory results show that Al, Fe and Mn average concentrations are higher than prescribed limits unlike others. The Contamination Indexes reveal that the elements are heavily loaded in the water. The exposure dose in both adults and children ranges from 0.021 in As to 181 in Fe (in adults) and from 0.068 in As to 576 in Fe (in children). The average Hazard Quotient (HQ) values for adults and children are generally lower than one except Mn that has average value greater than one in both age groups. However, for children, individual HQ in Fe in some of the locations are >1. The Hazard Index (HI)for adults and children ranged from low to high. The average values of Chronic Daily Intake (CDI) are generally <1. However, in children, values for Fe in some locations are >1. The average Carcinogenic Risk (CR) of Cr and Pb computed for adults and children indicated that the values are greater than the risk limit of 10-6 and 10-4. This could result in potential health risk to the consumers. The sources of these trace elements are largely from various anthropogenic activities and slightly from weathering of rocks in the study area. It is recommended that adequate and well monitored precautions need to be taken to safeguard the health of the consumers especially the children with low immunity.


Author(s):  
Obasi UCHE Orji ◽  
Udu Ama Ibiam ◽  
Nonso Joshua Awoke ◽  
Otuomasirichi Divine Obasi ◽  
Anayo Joseph Uraku ◽  
...  

Mining is one of the major sources of heavy metals in most developing countries and this has become a major health concern to the populace due to the possibility of food contamination with these heavy metals. We investigated the levels of titanium (Ti), manganese (Mn), nickel (Ni), copper (Cu), zinc (Zn), lead (Pb), rubidium (Rb), strontium (Sr), selenium (Se), niobium (Nb) and vanadium (V) in 64 soil and  320 samples of regularly consumed staple food crops and vegetables (cassava tubers, white yam, groundnut seed, fluted pumpkin leaf and Z. zanthoxyloides from farms around Enyigba mining sites in Ebonyi State and the possible health risks due to consumption of these staple foods. Energy dispersive X-ray fluorescence (EDXRF) was used in determination of the metals in the samples respectively. The mean levels of the metals except Mn, Pb and Zn were below the threshold limits for agricultural soils. Our data also showed that food crops cultivated around this sites bio-accumulated toxic levels of these metals above the recommended legal limits set by WHO, NAFDAC and CODEX especially Pb, Zn, Cu, Ni, Se, and Rb. This perhaps may have potential health implication on the local dwellers. The estimated daily intakes (EDI) of the toxic metals through the consumption of the crop samples were below the maximum tolerable daily intake (MTDI) except lead and nickel by eating of groundnut, cassava and yam. Furthermore, the target hazard quotient (THQ), computed based on EDI of the heavy metals were above unity for the metals due to cassava, yam and groundnut consumption, suggesting significant health risk. Raised amounts of heavy metal in cassava and groundnut samples as revealed by their metal extraction coefficient computed in this study hint that they may be used as bio-indicators of ecological, health hazards and phytoremediators of Mn, Zn, Cu, and Pb.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Defang Zeng ◽  
Saijun Zhou ◽  
Bozhi Ren ◽  
Tengshu Chen

Heavy metal pollution in soils caused by mining and smelting has attracted worldwide attention for its potential health risks to residents. This paper studies the concentrations and accumulations of Sb and As in both soils and vegetables and the human health risks of Sb and As in vegetables from Xikuangshan (XKS) Sb mine, Hunan, China. Results showed that the soils were severely polluted by Sb and As; Sb and As have significant positive correlation. Sb and As concentrations in vegetables were quite different:Coriandrum sativumL. was the highest in Sb,Allium fistulosumL. was the highest in As, andBrassica pekinensisL. was the lowest in both Sb and As;Daucus carotaL. andCoriandrum sativumL. showed advantage in accumulating Sb and As;Coriandrum sativumL. had higher capacity of redistributing Sb and As within the plant. Health risk assessment results showed that the hazard quotient (HQ) values of Sb and As in vegetables were in the ranges of 1.61–3.33 and 0.09–0.39, respectively; the chronic daily intake (CDI) and hazard quotient (HQ) values of Sb were over the safe limit recommended by FAO and WHO, indicating that long-term consumption of vegetables from the surrounding soils of XKS mine may bring health risks to residents.


Author(s):  
Ayobami Omozemoje Aigberua ◽  
Sylvester Chibueze Izah ◽  
Glory Richard

Introduction: An instance of fish deaths in marine waters surrounding some communities in Bonny and Andoni Local Government Areas in Rivers State was reported in March-April 2020. This study investigated trace metals hazard in muscle of Tilapia (Sarotherodon melanotheron) and Silver Catfish (Chrysichthys nigrodigitatus) from Okulu River, Rivers State, Nigeria. Materials and Methods: Tissues of 24 samples of Sarotherodon melanotheron and Chrysichthys nigrodigitatus obtained from the river were analyzed using atomic adsorption spectrophotometer, and the health risk was estimated based on estimated daily intake (EDI), target hazard quotient (THQ), and total target hazard quotient (TTHQ). Results: The concentration (mg/kg) of iron, zinc, manganese, copper, cadmium, lead, and chromium in both species ranged 4.00 – 197.30, 9.20 – 35.30, 0.20 – 5.00, 0.00 – 73.10, 0.00 – 1.30, 0.00 – 54.70, and 0.00 – 0.50, respectively. The EDI of trace metals resulting from the consumption of both fish species was higher than the permissible tolerance intake (PTI) mg/day/60kg body weight. The THQ and TTHQ were < 1, indicating that the consumption of this food fish portends no known health concern. However, the carcinogenic risks exceeded the threshold level of 10-6 - 10-4, thus, reflecting carcinogenic tendency. Based on the results obtained, it must be ensured that the effluents discharged into open water bodies meet the recommended limits. Conclusion: There is a need to create awareness among consumers of food fish in the study area. There should be periodic monitoring of trace metals in surface waters and its food fish population to forestall potential health impact on humans.


2020 ◽  
Vol 15 (3) ◽  
pp. 56-63
Author(s):  
L.U Usman ◽  
R. Yerima

Ingestion of vegetables containing heavy metal is one of the main ways in which these elements enter the human body. Once entered, heavy metals are deposited in bone and fat tissues, overlapping noble minerals. Slowly released into the body, heavy metals can cause an array of diseases. This study aimed to assess the heavy metals residues in some vegetables and potential health risk among consumers within Katsina Metropolis. Six different vegetable samples comprising of cucumber (Cucumis sativus), cabbage (Brassica oleracea), lettuce (Lactuca sativa), spinach (Spinacia oleracea), red pepper (Piper nigrum) and tomato (Lycopersicum esculentus) were randomly collected from two main irrigation farmland located in Katsina Metropolis (Kofar sauri and Kofar marusa). Their level of toxic metals namely (Copper, Zinc, Cadmium, Chromium and Lead) were assessed using standard materials and methods. Results obtained were used to estimate the health risk of these heavy metals via consumption of the vegetable samples. The results from the study showed that the mean heavy metal concentration ranged between 1.10±0.00 mg/kg to 4.45±0.16 mg/kg, 1.78±0.07 mg/kg to 4.9±0.11 mg/kg, 0.02±0.00 mg/kg to 1.28±0.02 mg/kg, 1.51±0.02 mg/kg to 4.34±0.02 mg/kg and 1.05±0.01 mg/kg to 2.86±0.02 mg/kg for Cu, Zn, Cd, Cr, and Pb respectively. The concentration of Cu and Zn were found to be below permissible limit while Cd, Cr and Pb concentration exceeded the permissible limit recommended by WHO/FAO. Health risks associated with the intake of these metals were evaluated in terms of estimated daily intake (EDI), hazard quotient (HQ) and hazard index (HI). EDI value of Cu and Zn were found to be below the maximum tolerable daily intake (MTDI). The HQ of all the metals were >1, suggesting health hazards risk for the population. Moreover, HQ of Cd and Pb were greatly higher through consumption of cucumber, cabbage, lettuce and red pepper indicating significant health risks. HI was found to be higher >1 (3.32 mg/kg and 3.91 mg/kg) in adult and children respectively for consumption of spinach; however, it was much higher >1 (10.49 mg/kg and 12.4 mg/kg) in adult and children respectively for consumption of cabbage, suggesting more adverse health effects from cabbage consumption than spinach. The findings of this study shows the health risks associated with the consumption of heavy metals through the intake of some the selected vegetables within Katsina Metropolis, therefore, there is need for biomonitoring of these heavy metals in the vegetable because these are some of the main sources of food for humans in many parts of the world. Keywords: Heavy metal, Estimated Daily Intake, Hazard Quotient, Hazard Index, Consumption


2013 ◽  
Vol 3 (1) ◽  
pp. 6 ◽  
Author(s):  
Bhupander Kumar ◽  
Virendra Kumar Verma ◽  
Ashis Kumar Naskar ◽  
Paromita Chakraborty ◽  
Sanjay Kumar ◽  
...  

People are encouraged to consume more fresh vegetables due to the high nutritional value and fibre contents in vegetables. At the same time, due to pesticidal residue in vegetables, vegetable consumption is considered as an important route of pesticides uptake by human beings. Pesticides, particularly organochlorines such as Aldrin, heptachlor and isomers of dichlorodiphe - nyltrichloroethane (DDT) and hexachlorocyclohexane (HCH) are a major concern because of their persistence, bioaccumulation, toxicity, and long-range environmental transport ability. Hence information on such toxic contaminants in vegetables is very essential, due to human health concern. In order to assess the potential health risks associated with vegetable consumption due to pesticidal residues of DDT and HCH, sixty four samples of commonly available vegetables were collected from a local market in West Bengal, India and analysed for DDT and HCH. In this study, estimated average daily intake of HCHs and DDTs through vegetables was ranged between 5.0x10<sup>&ndash;8</sup>&ndash;9.1x10<sup>&ndash;6</sup> mg kg<sup>&ndash;1</sup> day<sup>&ndash;1</sup> with an average value of 2.0x10<sup>&ndash;6</sup> mg kg<sup>&ndash;1</sup> day<sup>&ndash;1</sup>. Human health risk was assessed in terms of incremental lifetime cancer risk and health hazard index was between 1.7x10<sup>&ndash;8</sup>&ndash;8.8x10<sup>&ndash;6</sup> and 1.5x10<sup>&ndash;7</sup>&ndash; 1.7x10<sup>&ndash;2</sup>, respectively. Generated results were compared with maximum residual levels and reference values, were within acceptable limits and suggested no health risk to the human populations. Therefore, an extensive study on vegetables with the inclusion of other persistent organic pollutants and toxic metals should be carried out to know the overall scenario of contamination of vegetables.


2019 ◽  
Vol 17 (1) ◽  
pp. 1050-1060
Author(s):  
Chidinma C. Ezeofor ◽  
Janefrances N. Ihedioha ◽  
Oguejiofo T.Ujam ◽  
Nwachukwu R. Ekere ◽  
Charles O. Nwuche

AbstractThe potential toxic elements (Cu, Zn, Pb, Ni, Fe, Cr, Cd, Mn and Hg) were accumulated from rice grains and soil from an Ugbawka farm, Enugu State, Nigeria, which were determined to evaluate the potential health risk to rice consumers. The mean levels of metals found in soil (mg/kg) were as follows: Ni (0.57±0.24), Pb (2.44±0.17), Zn (3.35±2.05), Cu (0.71±0.33), Mn (37.72±10.97), Fe (13 856.6±31.43), Cr (2.51±0.98), Cd (0.51±1.36), and Hg (0.02±0.38); however metals found in rice grains (mg/ kg) were: Ni (0.81±0.72), Pb (0.94±0.70), Zn (8.22±2.97), Cu (0.59±0.42), Mn (13.30±4.56), Fe (13.28±0.73), Cr (15.00±10.00), Cd (0.36±0.07), and Hg (0.002±0.23). A small percentage (2.5%) of the soil samples were above the Chinese Maximum Allowable Concentration for cadmium in soil while cadmium and lead levels in the rice grains were above WHO permissible limit. Pearson’s correlations showed significant correlations amongst some metal pairs in soil and grains showing similarity in origin. The estimated daily intake of Pb was higher than the safety levels given by JECFA. Hazard Quotient for Pb and Total Hazard Index of all the metals were above one. This indicates possible potential health risk and adverse effect resulting from consumption of rice from Ugbawka farm.


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