scholarly journals “The Problem Is that We Hear a Bit of Everything…”: A Qualitative Systematic Review of Factors Associated with Alcohol Use, Reduction, and Abstinence in Pregnancy

2021 ◽  
Vol 18 (7) ◽  
pp. 3445
Author(s):  
Vivian Lyall ◽  
Lindsay Wolfson ◽  
Natasha Reid ◽  
Nancy Poole ◽  
Karen M. Moritz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alcohol Use ◽  
Individual Choice ◽  
Health And Wellness ◽  
Qualitative Systematic Review ◽  
Prenatal Alcohol Use ◽  
Systemic Factors ◽  
The Individual ◽  
The Impact ◽  
In Pregnancy

Understanding the factors that contribute to women’s alcohol use in pregnancy is critical to supporting women’s health and wellness and preventing Fetal Alcohol Spectrum Disorder. A systematic review of qualitative studies involving pregnant and recently postpartum women was undertaken to understand the barriers and facilitators that influence alcohol use in pregnancy (PROSPERO: CRD42018098831). Twenty-seven (n = 27) articles were identified through EMBASE, CINAHL, PsycINFO, PubMed and Web of Science. The included articles were thematically analyzed using NVivo12. The analysis was informed by Canada’s Action Framework for Building an Inclusive Health System to articulate the ways in which stigma and related barriers are enacted at the individual, interpersonal, institutional and population levels. Five themes impacting women’s alcohol use, abstention and reduction were identified: (1) social relationships and norms; (2) stigma; (3) trauma and other stressors; (4) alcohol information and messaging; and (5) access to trusted equitable care and essential resources. The impact of structural and systemic factors on prenatal alcohol use was largely absent in the included studies, instead focusing on individual choice. This silence risks perpetuating stigma and highlights the criticality of addressing intersecting structural and systemic factors in supporting maternal and fetal health.

scholarly journals Excess weight and dyslipidemia and their complications during pregnancy: a systematic review

2016 ◽  
Vol 16 (2) ◽  
pp. 93-101 ◽  
Author(s):  
Iramar Baptistella do Nascimento ◽  
Willian Barbosa Sales ◽  
Raquel Fleig ◽  
Grazielle Dutra da Silva ◽  
Jean Carl Silva
Keyword(s):  
Systematic Review ◽  
Key Words ◽  
Excess Weight ◽  
Cochrane Library ◽  
Obstetric Outcomes ◽  
Lipid Disorders ◽  
Key Words Lipids ◽  
The Cochrane Library ◽  
The Impact ◽  
In Pregnancy

Abstract Objectives: to identify bibliographically disorders related to excess weight, dyslipidemia and their complication during pregnancy and in the fetus and newborn. Methods: a systematic review including observational and interventional studies and reviews, based on MEDLINE, LILACS, Embase and the Cochrane Library between 2000 and 2015. The key-words "lipids, pregnancy, obesity and newborn" were used to establish a selective stage for inclusion/exclusion of titles, repeated studies, key-words, abstracts, methodological incompatibility and correlation with objectives. Results: 58 studies were selected, of which 36 (62%) addressed prevention and the risk in pregnancy of excess weight and lipid disorders and 19 (32.7%) suggestions and/or consequences for the fetus and newborn. Conclusions: excess weight and lipidemic disorders in pregnancy are causes for concern in scientific studies, posing risks both for the mother and the newborn. Higher prevalence of caesarian and pre-eclampsia were the two most noteworthy complications for gestational outcomes. In short, the impact on care of maternal habits and excess weight during pregnancy is highly significant, owing to the different degrees of complication in obstetric outcomes and their influence on the clinical characteristics of the newborn.

scholarly journals Phenoconversion of Cytochrome P450 Metabolism: A Systematic Review

2020 ◽  
Vol 9 (9) ◽  
pp. 2890 ◽  
Author(s):  
Sylvia D. Klomp ◽  
Martijn L. Manson ◽  
Henk-Jan Guchelaar ◽  
Jesse J. Swen
Keyword(s):  
Systematic Review ◽  
Cytochrome P450 ◽  
Study Data ◽  
Inclusion Criteria ◽  
Extrinsic Factors ◽  
Related Factors ◽  
Genotype Group ◽  
The Individual ◽  
Cancer And Inflammation ◽  
The Impact

Phenoconversion is the mismatch between the individual’s genotype-based prediction of drug metabolism and the true capacity to metabolize drugs due to nongenetic factors. While the concept of phenoconversion has been described in narrative reviews, no systematic review is available. A systematic review was conducted to investigate factors contributing to phenoconversion and the impact on cytochrome P450 metabolism. Twenty-seven studies met the inclusion criteria and were incorporated in this review, of which 14 demonstrate phenoconversion for a specific genotype group. Phenoconversion into a lower metabolizer phenotype was reported for concomitant use of CYP450-inhibiting drugs, increasing age, cancer, and inflammation. Phenoconversion into a higher metabolizer phenotype was reported for concomitant use of CYP450 inducers and smoking. Moreover, alcohol, pregnancy, and vitamin D exposure are factors where study data suggested phenoconversion. The studies reported genotype–phenotype discrepancies, but the impact of phenoconversion on the effectiveness and toxicity in the clinical setting remains unclear. In conclusion, phenoconversion is caused by both extrinsic factors and patient- and disease-related factors. The mechanism(s) behind and the extent to which CYP450 metabolism is affected remain unexplored. If studied more comprehensively, accounting for phenoconversion may help to improve our ability to predict the individual CYP450 metabolism and personalize drug treatment.

The impact of vitamin D in pregnancy on extraskeletal health in children: a systematic review

2012 ◽  
Vol 91 (12) ◽  
pp. 1368-1380 ◽  
Author(s):  
HENRIK T. CHRISTESEN ◽  
CLAES ELVANDER ◽  
RONALD F. LAMONT ◽  
JAN S. JØRGENSEN
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
The Impact ◽  
In Pregnancy

Area-level relative deprivation and alcohol use in Denmark: Is there a relationship?

2018 ◽  
Vol 47 (4) ◽  
pp. 428-438 ◽  
Author(s):  
Kim Bloomfield ◽  
Gabriele Berg-Beckhoff ◽  
Abdu Kedir Seid ◽  
Christiane Stock
Keyword(s):  
Alcohol Use ◽  
Relative Deprivation ◽  
Health Behaviours ◽  
Area Deprivation ◽  
Individual Level ◽  
Level Data ◽  
Housing Component ◽  
Disorder Identification ◽  
The Individual ◽  
The Impact

Aims: Greater area-level relative deprivation has been related to poorer health behaviours, but studies specifically on alcohol use and abuse have been equivocal. The main purpose of the present study was to investigate how area-level relative deprivation in Denmark relates to alcohol use and misuse in the country. Methods: As individual-level data, we used the national alcohol and drug survey of 2011 ( n= 5133). Data were procured from Statistics Denmark to construct an index of relative deprivation at the parish level ( n=2119). The deprivation index has two components, which were divided into quintiles. Multilevel linear and logistic regressions analysed the influence of area deprivation on mean alcohol use and hazardous drinking, as measured by the Alcohol Use Disorder Identification Test. Results: Men who lived in parishes designated as ‘very deprived’ on the socioeconomic component were more likely to consume less alcohol; women who lived in parishes designated as ‘deprived’ on the housing component were less likely to drink hazardously. But at the individual level, education was positively related to mean alcohol consumption, and higher individual income was positively related to mean consumption for women. Higher-educated men were more likely to drink hazardously. Conclusions: Area-level measures of relative deprivation were not strongly related to alcohol use, yet in the same models individual-level socioeconomic variables had a more noticeable influence. This suggests that in a stronger welfare state, the impact of area-level relative deprivation may not be as great. Further work is needed to develop more sensitive measures of relative deprivation.

A systematic review of the impact of malaria prevention in pregnancy on low birth weight and maternal anemia

2013 ◽  
Vol 121 (2) ◽  
pp. 103-109 ◽  
Author(s):  
Elizabeth M. McClure ◽  
Robert L. Goldenberg ◽  
Arlene E. Dent ◽  
Steven R. Meshnick
Keyword(s):  
Systematic Review ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Malaria Prevention ◽  
Maternal Anemia ◽  
The Impact ◽  
In Pregnancy

scholarly journals Binge drinking in young people: protocol for a systematic review of neuropsychological, neurophysiological and neuroimaging studies

BMJ Open ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. e023629 ◽  
Author(s):  
Briana Lees ◽  
Louise Mewton ◽  
Lexine Stapinski ◽  
Lindsay M Squeglia ◽  
Caroline Rae ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alcohol Use ◽  
Young People ◽  
Binge Drinking ◽  
Systematic Reviews ◽  
Meta Analysis ◽  
Primary Data ◽  
Eligibility Criteria ◽  
Cross Sectional ◽  
The Impact

IntroductionBinge drinking is the most common pattern of alcohol use among young people in Western countries. Adolescence and young adulthood is a vulnerable developmental period and binge drinking during this time has a higher potential for neurotoxicity and interference with ongoing neural and cognitive development. The purpose of this systematic review will be to assess and integrate evidence of the impact of binge drinking on cognition, brain structure and function in youth aged 10–24 years. Cross-sectional studies will synthesise the aberrations associated with binge drinking, while longitudinal studies will distinguish the cognitive and neural antecedents from the cognitive and neural effects that are a consequence of binge drinking.Methods and analysisA total of five peer-reviewed databases (PubMed, EMBASE, Medline, PsychINFO, ProQuest) will be systematically searched and the search period will include all studies published prior to 1 April 2018. The search terms will be a combination of MeSH keywords that are based on previous relevant reviews. Study selection will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and study quality will be assessed using The Grades of Recommendation, Assessment, Development and Evaluation approach. All studies will be screened against eligibility criteria designed to synthesise studies that examined a young binge drinking sample and used neuropsychological, neurophysiological or neuroimaging assessment techniques. Studies will be excluded if participants were significantly involved in other substances or if they had been clinically diagnosed with an alcohol use disorder, or any psychiatric, neurological or pharmacological condition. If available data permits, a meta-analysis will be conducted.Ethics and disseminationFormal ethics approval is not required as primary data will not be collected. The results will be disseminated through a peer-reviewed publication, conference presentations and social media.Trial registration numberInternational Prospective Register for Systematic Reviews (PROSPERO) number: CRD42018086856.

scholarly journals Discussing Personalized Prognosis in Amyotrophic Lateral Sclerosis: Development of a Communication Guide

2020 ◽  
Author(s):  
Remko M. van Eenennaam ◽  
Willeke J. Kruithof ◽  
Michael A. van Es ◽  
Esther T. Kruitwagen-van Reenen ◽  
Henk-Jan Westeneng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Amyotrophic Lateral Sclerosis ◽  
Information Needs ◽  
Time Range ◽  
Advisory Panel ◽  
Survival Prediction ◽  
Individual Needs ◽  
The Individual ◽  
The Impact ◽  
Lateral Sclerosis

Abstract Background: Personalized ENCALS survival prediction model reliably estimates the personalized prognosis of patients with amyotrophic lateral sclerosis. Concerns were raised on discussing personalized prognosis without causing anxiety and destroying hope. Tailoring communication to patient readiness and patient needs mediates the impact of prognostic disclosure. We developed a communication guide to support physicians in discussing personalized prognosis tailored to individual needs and preferences of people with ALS and their families.Methods: A multidisciplinary working group of neurologists, rehabilitation physicians, and healthcare researchers A) identified relevant topics for guidance, B) conducted a systematic review on needs of patients regarding prognostic discussion in life-limiting disease, C) drafted recommendations based on evidence and expert opinion, and refined and finalized these recommendations in consensus rounds, based on feedback of an expert advisory panel (patients, family member, ethicist and spiritual counsellor).Results: A) Topics identified for guidance were 1) filling in the ENCALS survival model, and interpreting outcomes and uncertainty, and 2) tailoring discussion to individual needs and preferences of patients (information needs, role and needs of family, severe cognitive impairment or frontotemporal dementia, and non-western patients). B) 17 studies were included in the systematic review. C) Consensus procedures on drafted recommendations focused on selection of outcomes, uncertainty about estimated survival, culturally sensitive communication, and lack of decisional capacity.Recommendations for discussing the prognosis include the following: discuss prognosis based on the prognostic groups and their median survival, or, if more precise information is desired, on the interquartile range of the survival probability. Investigate needs and preferences of the patients and their families for prognostic disclosure, regardless of cultural background. If the patient does not want to know their prognosis, with patient permission discuss the prognosis with their family. If the patient is judged to lack decisional capacity, ask the family if they want to discuss the prognosis. Tailor prognostic disclosure step by step, discuss it in terms of time range, and emphasize uncertainty of individual survival time.Conclusion: This communication guide supports physicians in tailoring discussion of personalized prognosis to the individual needs and preferences of people with ALS and their families.

scholarly journals The Normative Underpinnings of Population-Level Alcohol Use: An Individual-Level Simulation Model

2020 ◽  
Vol 47 (2) ◽  
pp. 224-234
Author(s):  
Charlotte Probst ◽  
Tuong Manh Vu ◽  
Joshua M. Epstein ◽  
Alexandra E. Nielsen ◽  
Charlotte Buckley ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Social Norms ◽  
Drinking Behavior ◽  
Population Level ◽  
Drinking Patterns ◽  
Individual Level ◽  
Behavioral Rules ◽  
Level Model ◽  
The Individual ◽  
The Impact

Background. By defining what is “normal,” appropriate, expected, and unacceptable, social norms shape human behavior. However, the individual-level mechanisms through which social norms impact population-level trends in health-relevant behaviors are not well understood. Aims. To test the ability of social norms mechanisms to predict changes in population-level drinking patterns. Method. An individual-level model was developed to simulate dynamic normative mechanisms and behavioral rules underlying drinking behavior over time. The model encompassed descriptive and injunctive drinking norms and their impact on frequency and quantity of alcohol use. A microsynthesis initialized in 1979 was used as a demographically representative synthetic U.S. population. Three experiments were performed in order to test the modelled normative mechanisms. Results. Overall, the experiments showed limited influence of normative interventions on population-level alcohol use. An increase in the desire to drink led to the most meaningful changes in the population’s drinking behavior. The findings of the experiments underline the importance of autonomy, that is, the degree to which an individual is susceptible to normative influence. Conclusion. The model was able to predict theoretically plausible changes in drinking patterns at the population level through the impact of social mechanisms. Future applications of the model could be used to plan norms interventions pertaining to alcohol use as well as other health behaviors.

Cultural distance and cross-border diffusion of innovation: a literature review

2020 ◽  
Vol 33 (2) ◽  
pp. 241-260
Author(s):  
Huimin Zhang ◽  
Mu Tian ◽  
Tsang Kai Hung
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
Diffusion Of Innovation ◽  
International Business ◽  
Cultural Distance ◽  
New Products ◽  
Content Type ◽  
Cross Border ◽  
The Individual ◽  
The Impact

PurposeThe objective of this study is to advance the understanding of the connection between cultural distance and the cross-border diffusion of innovations by conducting a systematic review and analysis of previous literature.Design/methodology/approachThis study involved a literature review. A total of 35 articles published in ABS journals were identified from key management, international business and marketing journals. The articles were analyzed by the methodologies and findings presented.FindingsThe literature review shows that the adoption and diffusion of innovation and new products are bound to be deeply influenced by cultural distance. Specifically, national cultures influence the willingness of consumers to buy new products at both the individual and organizational levels; organizational culture plays a key role in the process of launching new products and diffusing innovations to the market. However, existing studies and their findings are fragmented and inconsistent. Controversial views remain regarding the impact of national cultural dimensions on the diffusion of innovation at the individual and organizational levels.Originality/valueThis is the first systematic review of the literature specifically focusing on the impact of cultural distance on the cross-border diffusion of innovation. In identifying the research gaps and limitations of extant studies, the authors point to avenues for future research to develop a more integrated research agenda for marketing, management and international business research.

scholarly journals A Systematic Review of the Impact of Exposure to Internet-Based Alcohol-Related Content on Young People's Alcohol Use Behaviours

2016 ◽  
Vol 51 (6) ◽  
pp. 763-771 ◽  
Author(s):  
Himanshu Gupta ◽  
Simone Pettigrew ◽  
Tina Lam ◽  
Robert J Tait
Keyword(s):  
Systematic Review ◽  
Alcohol Use ◽  
The Impact
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