scholarly journals Biomarkers of Angiogenesis and Neuroplasticity as Promising Clinical Tools for Stroke Recovery Evaluation

2021 ◽  
Vol 22 (8) ◽  
pp. 3949
Author(s):  
Lidia Wlodarczyk ◽  
Rafal Szelenberger ◽  
Natalia Cichon ◽  
Joanna Saluk-Bijak ◽  
Michal Bijak ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Stroke Recovery ◽  
Clinical Scales ◽  
Recovery Processes ◽  
Recovery Potential ◽  
Current State ◽  
Standard Procedures ◽  
Key Issues ◽  
Clinical Tools ◽  
Selection Of

Several key issues impact the clinical practice of stroke rehabilitation including a patient’s medical history, stroke experience, the potential for recovery, and the selection of the most effective type of therapy. Until clinicians have answers to these concerns, the treatment and rehabilitation are rather intuitive, with standard procedures carried out based on subjective estimations using clinical scales. Therefore, there is a need to find biomarkers that could predict brain recovery potential in stroke patients. This review aims to present the current state-of-the-art stroke recovery biomarkers that could be used in clinical practice. The revision of biochemical biomarkers has been developed based on stroke recovery processes: angiogenesis and neuroplasticity. This paper provides an overview of the biomarkers that are considered to be ready-to-use in clinical practice and others, considered as future tools. Furthermore, this review shows the utility of biomarkers in the development of the concept of personalized medicine. Enhancing brain neuroplasticity and rehabilitation facilitation are crucial concerns not only after stroke, but in all central nervous system diseases.

Selection of high-quality sperm with thousands of parallel channels

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Mohammad Simchi ◽  
Jason Riordon ◽  
Jae Bem You ◽  
Yihe Wang ◽  
Sa Xiao ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Selectivity ◽  
High Yield ◽  
Sperm Selection ◽  
High Quality ◽  
Parallel Channels ◽  
Selection Of

A 3D-structured sperm selection device is presented that achieves both high selectivity and high yield via thousands of parallel channels. The device significantly outperforms the best clinical practice by selecting ∼100 000 of higher-quality sperm.

Second language structural priming: A critical review and directions for future research

2017 ◽  
Vol 34 (4) ◽  
pp. 539-552 ◽  
Author(s):  
Carrie N. Jackson
Keyword(s):  
Second Language ◽  
Future Research ◽  
Structural Priming ◽  
Cognitive Mechanisms ◽  
L2 Acquisition ◽  
Current State ◽  
Current Review ◽  
Open Questions ◽  
Key Issues ◽  
State Of Research

The last 15 years has seen a tremendous growth in research on structural priming among second language (L2) speakers. Structural priming is the phenomenon whereby speakers are more likely to repeat a structure they have recently heard or produced. Research on L2 structural priming speaks to key issues regarding the underlying linguistic and cognitive mechanisms that support L2 acquisition and use, and the extent to which lexical and grammatical information are shared across an L2 speaker’s languages. As the number of researchers investigating L2 priming and its implications for L2 learning continues to grow, it is important to assess the current state of research in this area and establish directions for continued inquiry. The goal of the current review is to provide an overview of recent research on within-language L2 structural priming, with an eye towards the open questions that remain.

Postgraduate Academic Desires: Senior Doctor of Pharmacy Students

1988 ◽  
Vol 22 (5) ◽  
pp. 422-424 ◽  
Author(s):  
Robert M. McNulty ◽  
Jay M. Mirtallo
Keyword(s):  
Clinical Practice ◽  
Work Experience ◽  
Postgraduate Training ◽  
General Medicine ◽  
Postgraduate Education ◽  
Senior Doctor ◽  
Bachelor Of Science ◽  
Or Practice ◽  
Doctor Of Pharmacy ◽  
Selection Of

Senior Doctor of Pharmacy (Pharm.D.) students were surveyed by questionnaire to glean information about academic training, and residency, fellowship, or practice positions sought after graduation. There were 227 (27 percent of total surveys) responses. Of those responding, 71 percent were Bachelor of Science graduates, 29 percent were Pharm.D. primary degree students, and 18 percent completed a residency either before or during Pharm.D. training. Fifty percent had an average of three years of clinical services work experience prior to their Pharm.D. education. There was strong interest in postgraduate education by respondents: 41 percent for residencies and 26 percent for fellowships. Of resident candidates, 18 percent and 49 percent, respectively, considered research essential and important to the program. Areas of greatest interest in residencies were general medicine, infectious disease, and pharmacokinetics. Important to the selection of a fellowship was the research proposal and concurrent clinical practice. Pharm.D. students are interested in postgraduate training as residents (60 percent), fellows (38 percent), or both (2 percent). Desired activities are research and clinical practice independent of residency or fellowship interest.

Questions Collaborative Dexamethasone Trial

PEDIATRICS ◽  
1992 ◽  
Vol 89 (6) ◽  
pp. 1266-1266
Author(s):  
ROSAMOND JONES ◽  
ADRIAN GRANT ◽  
Keyword(s):  
Clinical Practice ◽  
Random Sample ◽  
Human Beings ◽  
Eligibility Criteria ◽  
Clinical Uncertainty ◽  
Trial Entry ◽  
Selection Of

In Reply.— We are glad to respond to Dr MacMahon's letter about the generalizability of the results of our trial. Basing trial entry on `clinical uncertainty' is actually one of the strengths of this trial.1 No trial can ever include a random sample of all human beings who meet the eligibility criteria; there is always selection of subjects (whatever the entry criteria). Inevitably, therefore, at some point there has to be a leap of faith from the evidence to clinical practice.2

Actual Issues оf Bilingual Hungarian-Bulgarian Lexicography

2021 ◽  
Vol 48 (2) ◽  
pp. 119-129
Author(s):  
Lilyana Lesnichkova ◽  
Keyword(s):  
Foreign Language ◽  
Academic English ◽  
Current State ◽  
The Creation ◽  
Theoretical Foundations ◽  
Selection Of

The article focuses on the presentation of the Hungarian-Bulgarian valence dictionary, which is currently in preparation, against the background of an extremely actual task – the creation of an academic English-Bulgarian dictionary, adequately reflecting the current state of vocabulary in both languages. The author substantiates the need for such a dictionary, given the lack of general and specialized Hungarian-Bulgarian dictionaries, based on the theoretical foundations and principles of modern lexicography. Outlined are the main features of the dictionary, the specificities and approaches in the work of its compilation. The selection of material and the methods of its presentation are in accordance with the practical needs of learners of Hungarian as a foreign language.

scholarly journals Probabilistic-deterministic approach of controlling the functionality of a technical system in normal and emergency operation modes

2018 ◽  
Vol 226 ◽  
pp. 04008
Author(s):  
Vladimir M. Zababurin ◽  
Marina A. Egorova ◽  
Yuliya A. Polyakova
Keyword(s):  
Open Systems ◽  
System Development ◽  
Emergency Situation ◽  
Emergency Operation ◽  
Technical System ◽  
Emergency Situations ◽  
Recovery Processes ◽  
Current State ◽  
Self Organized Criticality ◽  
Technical Systems

The main disadvantages of the existing methods of managing the current state of technical systems are revealed. A non-standard approach is proposed for managing the functionality of the system in emergency situations. The character of the dynamics of the recovery processes of the technical system is determined as its state approaches the emergency one on the basis of the recommendations of the theory of self-organized criticality (SOC). The physical criteria for assessing the current state of the technical system are revealed. The rationale for using the physical indicator of the functional destabilization of the system is given. The signs of the pre-emergency state of the technical system are considered. A grapho-analytical model for the development of an emergency situation has been developed. The fact of the inevitable increase in the entropy of the system upon its transition to an emergency state is established. Structuring of the system development process in an emergency situation is carried out in three stages. The methodology for estimating the pre-emergency state of complex open systems is presented. The advantages of the proposed approach to managing the state of technical systems in comparison with traditional ones are established.

scholarly journals Women in oncology pharmacy leadership: A white paper

2019 ◽  
Vol 26 (1) ◽  
pp. 175-186
Author(s):  
Alexandra Shillingburg ◽  
Laura B Michaud ◽  
Rowena Schwartz ◽  
Jaime Anderson ◽  
David W Henry ◽  
...  
Keyword(s):  
Leadership Development ◽  
White Paper ◽  
Gender Disparity ◽  
Professional Organizations ◽  
Leadership Roles ◽  
Leadership Positions ◽  
Call To Action ◽  
Current State ◽  
Key Issues ◽  
Development Committee

Gender disparity exists in leadership roles within healthcare. While the majority of the healthcare workforce is comprised of women, significantly fewer women occupy leadership positions, particularly at executive and board levels. As the field of oncology pharmacy continues to rapidly expand and evolve, an assessment of the current state of women in oncology pharmacy leadership roles is vital to the growth and development of the profession. In the fall of 2017, the Hematology/Oncology Pharmacy Association (HOPA) hosted a summit to explore leadership issues facing women in oncology pharmacy which have the potential to affect our membership and our profession. This meeting included invited participants from across the fields of oncology and pharmacy and was part of HOPA’s strategic leadership initiative developed through the work of the HOPA Leadership Development Committee in 2016. This promotes a primary goal of HOPA, which is to support oncology pharmacists as they assume leadership roles within their practices and within healthcare to assure oncology pharmacy is integrated into cancer care. The purpose of this white paper is to (1) summarize key issues that were identified through a membership survey; (2) review ongoing efforts to address the needs of female oncology pharmacists in leadership development; (3) serve as a call to action for individuals and professional organizations to assist with and disseminate these efforts and highlight available resources, and (4) to provide practical steps to meet the needs of individuals, training programs, and institutions/employers.

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