scholarly journals Reconfigurable Dual Peptide Tethered Polymer System Offers a Synergistic Solution for Next Generation Dental Adhesives

2021 ◽  
Vol 22 (12) ◽  
pp. 6552
Author(s):  
Esra Yuca ◽  
Sheng-Xue Xie ◽  
Linyong Song ◽  
Kyle Boone ◽  
Nilan Kamathewatta ◽  
...  
Keyword(s):  
Dental Materials ◽  
Polymer System ◽  
Adhesive System ◽  
Degradation Process ◽  
Peptide Sequence ◽  
Next Generation ◽  
Dental Adhesives ◽  
Tooth Structure ◽  
Low Viscosity ◽  
Restorative Dental Materials

Resin-based composite materials have been widely used in restorative dental materials due to their aesthetic, mechanical, and physical properties. However, they still encounter clinical shortcomings mainly due to recurrent decay that develops at the composite-tooth interface. The low-viscosity adhesive that bonds the composite to the tooth is intended to seal this interface, but the adhesive seal is inherently defective and readily damaged by acids, enzymes, and oral fluids. Bacteria infiltrate the resulting gaps at the composite-tooth interface and bacterial by-products demineralize the tooth and erode the adhesive. These activities lead to wider and deeper gaps that provide an ideal environment for bacteria to proliferate. This complex degradation process mediated by several biological and environmental factors damages the tooth, destroys the adhesive seal, and ultimately, leads to failure of the composite restoration. This paper describes a co-tethered dual peptide-polymer system to address composite-tooth interface vulnerability. The adhesive system incorporates an antimicrobial peptide to inhibit bacterial attack and a hydroxyapatite-binding peptide to promote remineralization of damaged tooth structure. A designer spacer sequence was incorporated into each peptide sequence to not only provide a conjugation site for methacrylate (MA) monomer but also to retain active peptide conformations and enhance the display of the peptides in the material. The resulting MA-antimicrobial peptides and MA-remineralization peptides were copolymerized into dental adhesives formulations. The results on the adhesive system composed of co-tethered peptides demonstrated both strong metabolic inhibition of S. mutans and localized calcium phosphate remineralization. Overall, the result offers a reconfigurable and tunable peptide-polymer hybrid system as next-generation adhesives to address composite-tooth interface vulnerability.

scholarly journals Clinical Protocol for Esthetic Restoration using a Self-etching Adhesive

2013 ◽  
Vol 4 (3) ◽  
pp. 202-207
Author(s):  
Mateus Rodrigues Tonetto ◽  
Alvaro Henrique Borges ◽  
Matheus Coelho Bandeca ◽  
Fausto Frizzera Borges ◽  
Lucas Fontanari ◽  
...  
Keyword(s):  
Dental Materials ◽  
Adhesive System ◽  
Clinical Protocols ◽  
Central Incisor ◽  
Adhesive Systems ◽  
Clinical Protocol ◽  
Present Case Report ◽  
Tooth Structure ◽  
Anterior Teeth ◽  
Postoperative Sensitivity

ABSTRACT The advent of new adhesive systems is making techniques and clinical protocols to become faster and simpler, however it does not reduce the importance of knowledge of the properties, characteristics and interaction of dental materials with the tooth structure. Among the adhesives that have recently emerged, highlight the self-etching systems, especially the two-step selfetching, in which the acid primer is available in a separate bottle from the adhesive. These adhesives have shown good results for bond strength, microleakage and postoperative sensitivity, being an option for direct adhesive restorations in anterior teeth. This way, the present case report describes the step-by-step making of a class IV restoration in an upper right central incisor using atwo-step adhesive system, obtaining satisfactory results. How to cite this article Tonetto MR, Borges FF, Fontanari L, Borges AH, Bandeca MC, de Andrade MF. Clinical Protocol for Esthetic Restoration using a Self-etching Adhesive. World J Dent 2013;4(3):202-207.

scholarly journals Effects of ionizing radiation on surface properties of current restorative dental materials

2021 ◽  
Vol 32 (6) ◽  
Author(s):  
Débora Michelle Gonçalves de Amorim ◽  
Aretha Heitor Veríssimo ◽  
Anne Kaline Claudino Ribeiro ◽  
Rodrigo Othávio de Assunção e Souza ◽  
Isauremi Vieira de Assunção ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Surface Properties ◽  
Resin Composite ◽  
Dental Materials ◽  
Glass Ionomer Cement ◽  
Contact Angles ◽  
Glass Ionomer ◽  
Post Radiation ◽  
Restorative Dental Materials ◽  
Ionomer Cement

AbstractTo investigate the impact of radiotherapy on surface properties of restorative dental materials. A conventional resin composite—CRC (Aura Enamel), a bulk-fill resin composite—BFRC (Aura Bulk-fill), a conventional glass ionomer cement—CGIC (Riva self cure), and a resin-modified glass ionomer cement—RMGIC (Riva light cure) were tested. Forty disc-shaped samples from each material (8 mm diameter × 2 mm thickness) (n = 10) were produced according to manufacturer directions and then stored in water distilled for 24 h. Surface wettability (water contact angle), Vickers microhardness, and micromorphology through scanning electron microscopy (SEM) before and after exposition to ionizing radiation (60 Gy) were obtained. The data were statistically evaluated using the two-way ANOVA and Tukey posthoc test (p < 0.05). Baseline and post-radiation values of contact angles were statistically similar for CRC, BFRC, and RMGIC, whilst post-radiation values of contact angles were statistically lower than baseline ones for CGIC. Exposition to ionizing radiation statistically increased the microhardness of CRC, and statistically decreased the microhardness of CGIC. The surface micromorphology of all materials was changed post-radiation. Exposure to ionizing radiation negatively affected the conventional glass ionomer tested, while did not alter or improved surface properties testing of the resin composites and the resin-modified glass ionomer cement tested.

Development of a novel biocompatible polymer system for extended drug release in a next-generation drug-eluting stent

2008 ◽  
Vol 85A (4) ◽  
pp. 1064-1071 ◽  
Author(s):  
Kishore Udipi ◽  
Mingfei Chen ◽  
Peiwen Cheng ◽  
Kevin Jiang ◽  
Diane Judd ◽  
...  
Keyword(s):  
Drug Release ◽  
Polymer System ◽  
Drug Eluting Stent ◽  
Next Generation ◽  
Biocompatible Polymer ◽  
Drug Eluting

Measurement of the fluorescence of restorative dental materials using a 655-nm diode laser

2001 ◽  
Author(s):  
Fatima A. A. Zanin ◽  
Dilma H. Souza-Campos ◽  
Sissi Zanin ◽  
Aldo Brugnera, Jr. ◽  
Jesus D. Pecora ◽  
...  
Keyword(s):  
Diode Laser ◽  
Dental Materials ◽  
Restorative Dental Materials

scholarly journals Hard dental tissue minimal-invasive preparation using contemporary polymer rotating instruments and laser

2014 ◽  
Vol 142 (5-6) ◽  
pp. 365-370 ◽  
Author(s):  
Milos Beloica ◽  
Zoran Vulicevic ◽  
Zoran Mandinic ◽  
Ivana Radovic ◽  
Olivera Jovicic ◽  
...  
Keyword(s):  
New Technology ◽  
Dental Materials ◽  
Pediatric Dentistry ◽  
Minimal Invasive ◽  
Dental Tissue ◽  
Cavity Preparation ◽  
Tooth Structure ◽  
Dental Tissues ◽  
The Difference ◽  
Preparation Techniques

Goal of contemporary dentistry is to decrease the patient?s discomfort during treatment. Dentists aim to achieve maximum with the newly developed dental materials as well as with new cavity preparation techniques in the shortest time span. Since the development of the first constructed borer (drilling machine) for caries removal, the preparation techniques have considerably changed. The progress of dental materials as well as the cavity preparation techniques has led us to contemporary carbide tungsten and diamond borers that are used with obligatory water cooling. The innovation within this field represents newly developed polymer borers that can detect the difference between carious lesions and healthy tooth structure. In this way the cavity preparation may be performed without damaging dental healthy tissue. This is possible owing to their hardness which is lower than the hardness of intact dentin. Polymer borer preparation is painless with less vibration, while the increase in temperature is negligible. Lasers have been used in clinical dentistry since 1980s so it can be said that they represent a new technology. The function of lasers is based on ablation which requires water. Erbium lasers have shown the highest potential with their ability to produce effective ablation of hard dental tissues. Laser application in dentistry requires special training as well as some protective measures. Laser advantages, compared to traditional preparation techniques, involve the absence of vibration, painless preparation, possibility of preparation without anesthetic and easier patient?s adjustment to dental intervention which is of importance, especially in pediatric dentistry.

scholarly journals Pengaruh Penambahan Hidroksiapatit dari Cangkang Telur Ayam Terhadap Kekerasan Permukaan GIC

2016 ◽  
Vol 5 (2) ◽  
pp. 8
Author(s):  
Putri Ajri Mawadara ◽  
Martha Mozartha ◽  
Trisnawaty K
Keyword(s):  
Dental Materials ◽  
Surface Hardness ◽  
T Test ◽  
Control Group ◽  
System A ◽  
Significant Difference ◽  
Calcium Source ◽  
Chicken Eggshell ◽  
Restorative Dental Materials ◽  
Experimental Group

Hydroxyapatite (HA) is a bioceramic with excellentbiocompatible properties, and composition and crystal structure similar to apatite in the human dental structure and skeletal system. A number of researchers have attempted to evaluate the effect of the addition of HA powders to increasemechanical properties of restorative dental materials. In this study, HA was synthesized using chicken eggshell as calcium source for synthesizing HA by using precipitation technique. The aim of this study was to determine the effect of incorporation of eggshell-derived HA on the surface  hardness GIC (Fuji IX GP). Specimens were divided into two groups: group GIC without incorporation of HA as control group (n = 16) and group GIC with incorporation of 5% HA as experimental group (n = 16). Total of specimens were 32 cylinders 5mm diameter and 2mm height. Surface hardness GIC was measured with vickers microhardness tester. Data wasanalyzed by unpaired T-test. The mean of surface hardness for GIC control group was 51.37 ± 1,63VHN and the experimental group was 56.60 ± 1,22HVN. The results T-test showed a significant difference between groups (p<0.05). It can be concluded thatincorporation of eggshell-derivedHA could increasesurface hardness of GIC.

Assessing Restorative Dental Materials: 1. Test Methods and Assessment of Results

Dental Update ◽  
2002 ◽  
Vol 29 (4) ◽  
pp. 188-194 ◽  
Author(s):  
F.J.T. Burke ◽  
A.C.C. Shortall ◽  
E.C. Combe ◽  
T.C. Aitchison
Keyword(s):  
Dental Materials ◽  
Test Methods ◽  
Restorative Dental Materials

scholarly journals Biological restorations as a treatment option for primary molars with extensive coronal destruction: report of two cases

2007 ◽  
Vol 18 (3) ◽  
pp. 248-252 ◽  
Author(s):  
Karina Sanches ◽  
Fabrício Kitazono de Carvalho ◽  
Paulo Nelson-Filho ◽  
Sada Assed ◽  
Francisco Wanderley Garcia de Paula e Silva ◽  
...  
Keyword(s):  
Glass Ionomer Cement ◽  
Adhesive System ◽  
Tooth Surface ◽  
Primary Molars ◽  
Glass Ionomer ◽  
Technical Aspects ◽  
Tooth Structure ◽  
Occlusal Adjustment ◽  
Carious Lesions ◽  
Ionomer Cement

This article reports the cases of two young children aged 4 and 5 years, in whom biological restorations using tooth fragments were placed in primary molars with severely damaged crowns due to extensive carious lesions. After radiographic and clinical evaluation, tooth fragments obtained from extracted teeth in stock were autoclaved, adjusted to the prepared cavity and bonded to the remaining tooth structure with either adhesive system (Case 1) or dual-cure resin-based cement (Case 2) over a calcium hydroxide layer and a glass ionomer cement base. Occlusal adjustment was performed and topical sodium fluoride was applied to tooth surface. Periodical clinical and radiographic controls were carried out and the restored teeth were followed up for 4 and 3 years, respectively, until exfoliation. In these two reports, the technical aspects are described and the benefits and disadvantages of biological restorations as an alternative treatment for rehabilitation of severely destroyed primary molars are discussed.

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