scholarly journals The Functional Properties of Mg–Zn–X Biodegradable Magnesium Alloys

Materials ◽  
2020 ◽  
Vol 13 (3) ◽  
pp. 544 ◽  
Author(s):  
Dmitry Merson ◽  
Alexander Brilevsky ◽  
Pavel Myagkikh ◽  
Alexandra Tarkova ◽  
Alexei Prokhorikhin ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Magnesium Alloys ◽  
Functional Properties ◽  
Biomedical Applications ◽  
Mechanical Performance ◽  
Chemical Compositions ◽  
Premature Failure ◽  
Inflammatory Reactions ◽  
Biodegradable Magnesium

The implantation of metallic devices in orthopaedic surgical procedures and coronary angioplasty is associated with the risk of various adverse events: (i) mechanical (premature failure), (ii) chemo-mechanical (corrosion and corrosion-fatigue degradation) and (iii) biomedical (chronic local inflammatory reactions, tissue necrosis, etc.). In this regard, the development of biodegradable implants/stents, which provide the necessary mechanical support for the healing period of the bone or the vessel wall and then are completely resorbed, has bright prospects. Magnesium alloys are the most suitable candidates for that purpose due to their superior mechanical performance, bioresorbability and biocompatibility. This article presents the results of the comparative research on several wrought biodegradable alloys, assessing their potential for biomedical applications. The Mg–Zn–X alloys with different chemical compositions and microstructures were produced using severe plastic deformation techniques. Functional properties pivotal for biomedical applications—mechanical strength, in vitro corrosion resistance and cytotoxic activity—were included in the focus of the study. Excellent mechanical performance and low cytotoxic effects are documented for all alloys with a notable exception for one of two Mg–Zn–Zr alloys. The in vitro corrosion resistance is, however, below expectations due to critical impurities, and this property has yet to be drastically improved through the cleaner materials fabrication processing before they can be considered for biomedical applications.

scholarly journals Differential apoptotic response of MC3T3-E1 pre-osteoblasts to biodegradable magnesium alloys in an in vitro direct culture model

2017 ◽  
Vol 28 (10) ◽  
Author(s):  
Ehsan Bonyadi Rad ◽  
Sepideh Mostofi ◽  
Matthias Katschnig ◽  
Patrik Schmutz ◽  
Magdalena Pawelkiewicz ◽  
...  
Keyword(s):  
Magnesium Alloys ◽  
Apoptotic Response ◽  
Culture Model ◽  
Biodegradable Magnesium

Effect of extrusion treatment on mechanical, thermal conductivity and corrosion resistance of magnesium alloys

2019 ◽  
Vol 9 (5) ◽  
pp. 405-412
Author(s):  
Bo Zhang ◽  
Huichao Jia ◽  
Quanyong Lian ◽  
Lianyu Jiang ◽  
Guangxin Wu
Keyword(s):  
Mechanical Properties ◽  
Thermal Conductivity ◽  
Corrosion Resistance ◽  
Thermal Properties ◽  
Magnesium Alloys ◽  
Driving Force ◽  
Mechanical Performance ◽  
Cast Alloy ◽  
Extrusion Temperature ◽  
Zr Alloys

The effect of extrusion treatment on the mechanical, thermal and corrosion resistance of Mg–La–Zn–Zr alloys were presented. It is suggested that the amount of recrystallized grains played a major role in both mechanical properties and thermal properties. It should be noted the as-cast alloy shows the best thermal conductivity reached the value about 137.507 W/(m · K), however, the mechanical performance of magnesium alloys does not reach the expected results. The thermal properties of extruded alloys have slightly decreased and then increased with the increase of extrusion temperature. Then the tensile properties of Mg–La–Zn–Zr were significantly improved after extrusion treatment. Furthermore, with the increase of extrusion temperature, the elongation-to-fracture increased substantially. After extrusion treatment, the corrosion driving force of the alloy decreases, which reduces the corrosion tendency of the magnesium alloy. The alloy presented in this paper is expected to be applied in industry.

Growth, in vitro biodegradation and cytocompatibility properties of nano-hydroxyapatite coatings on biodegradable magnesium alloys

2016 ◽  
Vol 672 ◽  
pp. 366-373 ◽  
Author(s):  
Huawei Yang ◽  
Kada Xia ◽  
Taolei Wang ◽  
Junchao Niu ◽  
Yiming Song ◽  
...  
Keyword(s):  
Magnesium Alloys ◽  
Hydroxyapatite Coatings ◽  
Biodegradable Magnesium

Biodegradable Magnesium Implant: In Vivo and In Vitro Convergence

2014 ◽  
Author(s):  
Yeoheung Yun ◽  
Yongseok Jang ◽  
Juan Wang ◽  
Zhongyun Dong ◽  
Vesselin Shanov ◽  
...  
Keyword(s):  
Magnesium Alloys ◽  
Product Formation ◽  
In Vitro Test ◽  
Biodegradable Implant ◽  
Plasma Electrolyte ◽  
Vitro Test ◽  
Plasma Electrolyte Oxidation ◽  
Biodegradable Magnesium

In recent years, magnesium alloys have emerged as possible biodegradable implant material. A fundamental understanding of the nature of magnesium corrosion and the ability to control this process in vivo is critical to advancing the case for clinical use of magnesium based biomaterials. The biodegradation of magnesium is fundamentally linked to studies of its corrosion, which is dependent on the interfacing dynamics between the material and its environment. Thus, it is required to confirm what variable differentiate the corrosion behavior between in vitro and in vivo before optimizing and standardizing of in vitro test. This study was conducted to understand the biodegradation behavior of commercial AZ31 and Mg-Zn-Ca alloys with plasma electrolyte oxidation (PEO) under various biological environments using in vivo and in vitro testing methods mimicking in vivo physiological environment. This study is focused on the effect of Zn element concentration and PEO coating for magnesium alloys, and the correlation between the in vivo and in vitro in terms of corrosion rate, types of corrosion and corrosion product formation.

scholarly journals Tunable Microstructure and Morphology of the Self-Assembly Hydroxyapatite Coatings on ZK60 Magnesium Alloy Substrates Using Hydrothermal Methods

Coatings ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 8
Author(s):  
Taolei Wang ◽  
Chao Lin ◽  
Dan Batalu ◽  
Jingzhou Hu ◽  
Wei Lu
Keyword(s):  
Corrosion Resistance ◽  
Magnesium Alloys ◽  
Self Assembly ◽  
Ph Value ◽  
Precursor Solution ◽  
Electrochemical Tests ◽  
Ha Coating ◽  
Hydroxyapatite Coatings ◽  
And Performance ◽  
Biodegradable Magnesium

Hydroxyapatite coatings have been widely used to improve the corrosion resistance of biodegradable magnesium alloys. In this paper, in order to manufacture the ideal hydroxyapatite (HA) coating on the ZK60 magnesium substrate by hydrothermal method, formation mechanism of enhanced hydroxyapatite (HA) coatings, influence of pH values of the precursor solution on the HA morphology, corrosion resistance and cytotoxicity of HA coatings have been investigated. Results show that the growth pattern of the HA is influenced by the local pH value. HA has a preferential c-axis and higher crystallinity in the alkaline environment developing a nanorod-like structure, while in acid and neutral environments it has a preferential growth along the a(b)-plane with a lower crystallinity, developing a nanosheet-like structure. The different morphology and microstructure lead to different degradation behavior and performance of HA coatings. Immersion and electrochemical tests show that the neutral environment promote formation of HA coatings with high corrosion resistance. The cell culture experiments confirm that the enhanced corrosion resistance assure the biocompatibility of the substrate-coating system. In general, the HA coating prepared in neutral environment shows great potential in surface modification of magnesium alloys.

Fabrication of Bioactive HA/Ti Composite Coating by Laser Cladding

2007 ◽  
Vol 330-332 ◽  
pp. 569-572 ◽  
Author(s):  
Sen Yang ◽  
Hau Chung Man
Keyword(s):  
Composite Coating ◽  
Laser Cladding ◽  
Biomedical Applications ◽  
Bone Growth ◽  
Niti Alloy ◽  
Experimental Result ◽  
Chemical Compositions ◽  
X Ray ◽  
Metallurgical Bonding

To accelerate the bone growth around a metallic implant and to achieve the mechanical characteristics needed for biomedical applications, a HA/Ti composite coating was produced on NiTi alloy substrate by laser cladding. The chemical compositions, microstructures and surface morphology of the cladded layer were analyzed using energy dispersive X-ray spectroscopy (EDX), scanning electron microscopy (SEM), and X-ray diffractometry (XRD). The experimental results showed that an excellent metallurgical bonding between the coating and the substrate was obtained. Owing to decomposition of HA under irradiation of high power laser, the microstructures in bioceramics coating were mainly composed of CaO, CaTiO3, Ti4P3, and HA phases. In vitro experimental result showed that HA/Ti composite coating made the bioactivity of NiTi alloy improve remarkably, which would promote the bone growth and could restrain Ni ion releasing from NiTi alloy.

Sign in / Sign up

Export Citation Format

Share Document