scholarly journals Commercial Bone Grafts Claimed as an Alternative to Autografts: Current Trends for Clinical Applications in Orthopaedics

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3290
Author(s):  
Marco Govoni ◽  
Leonardo Vivarelli ◽  
Alessandro Mazzotta ◽  
Cesare Stagni ◽  
Alessandra Maso ◽  
...  
Keyword(s):  
Web Of Science ◽  
Bone Grafts ◽  
Clinical Applications ◽  
Bibliographic Databases ◽  
Market Demand ◽  
Regulatory Issues ◽  
Negative Results ◽  
Current Trends ◽  
Analyse Data ◽  
Cellular Bone

In the last twenty years, due to an increasing medical and market demand for orthopaedic implants, several grafting options have been developed. However, when alternative bone augmentation materials mimicking autografts are searched on the market, commercially available products may be grouped into three main categories: cellular bone matrices, growth factor enhanced bone grafts, and peptide enhanced xeno-hybrid bone grafts. Firstly, to obtain data for this review, the search engines Google and Bing were employed to acquire information from reports or website portfolios of important competitors in the global bone graft market. Secondly, bibliographic databases such as Medline/PubMed, Web of Science, and Scopus were also employed to analyse data from preclinical/clinical studies performed to evaluate the safety and efficacy of each product released on the market. Here, we discuss several products in terms of osteogenic/osteoinductive/osteoconductive properties, safety, efficacy, and side effects, as well as regulatory issues and costs. Although both positive and negative results were reported in clinical applications for each class of products, to date, peptide enhanced xeno-hybrid bone grafts may represent the best choice in terms of risk/benefit ratio. Nevertheless, more prospective and controlled studies are needed before approval for routine clinical use.

Efficacy of the detection of the early symptoms of Cancer cell, Prevention and the diagnosis procedure

2020 ◽  
Vol 16 ◽  
Author(s):  
Md Mahfujul Islam ◽  
Md Al Amin Molla
Keyword(s):  
Cancer Cells ◽  
Reference Lists ◽  
Web Of Science ◽  
Screening Program ◽  
Bibliographic Databases ◽  
Controlled Trials ◽  
Conference Paper ◽  
Cancer Awareness ◽  
Short Term ◽  
Randomized Controlled

: The aim to examine the signs for the potency of interventions to raise cancer awareness along with promote early demonstration in most cancers to share with future and policy investigation. Several peer-reviewed journals as well as books, conference paper and authentic website (like as NCBI, PubMed, CRI, CRU, Google Scholar, MEDLINE, Web of Science, etc.) Also, we looked for bibliographic databases and reference lists Such as randomized controlled trials of interventions brought to Individuals and commanded or uncontrolled reports of interventions brought to communities. The results found the signs that interventions reach to people subconsciously increase the cancer awareness from the short term and inadequate signs they advertise premature demonstration. This analysis helps to find appropriate info about categorizing the early indicators of many kinds of cancer cells on addition to appropriate guidelines to conquer cancer in low-Mid center income areas. Whereas contained the structured screening program, which helps detect cancer early and having a heightened chance of therapeutic and treatment content, taking essential measures to elevate the consciousness of the detectable symptoms.

scholarly journals Systematic Review of Alexithymia in the Population of Hemodialysis Patients

2021 ◽  
Vol 10 (13) ◽  
pp. 2862
Author(s):  
Đorđe Pojatić ◽  
Ivana Tolj ◽  
Davorin Pezerović ◽  
Dunja Degmečić
Keyword(s):  
Mental Health ◽  
Literature Review ◽  
Web Of Science ◽  
Major Effect ◽  
Hemodialysis Patients ◽  
Bibliographic Databases ◽  
Inclusion Criteria ◽  
The Matrix ◽  
Negative Effect ◽  
Bodily Sensations

Alexithymia is a construct defined as the inability to differentiate between emotional experiences and bodily sensations. According to existing knowledge, alexithymia may have a major effect on the process of treatment and the outcome of the hemodialysis disease. The objective of this literature review was to determine the significance that alexithymia has for compliance and variables of clinical and mental health in the population of hemodialysis patients. For the above purpose, bibliographic databases “MEDLINE” and “Web of Science” were searched. The matrix method was used in analysis of articles. Searching both databases resulted in 248 articles. After applying exclusion and inclusion criteria, we included results of 13 articles in the literature review. The results of the search are findings regarding the prevalence and correlation of alexithymia with variables of clinical and mental health in hemodialysis patients. Alexithymia is significantly more common in the population of hemodialysis patients, and it has a negative effect on their mental and somatic health. Alexithymia levels in hemodialysis patients are more pronounced in cases where there is a greater number of comorbidities. Alexithymia is the predictor of high mortality rate in the population of hemodialysis patients, independent of other comorbidities.

scholarly journals Impact of Educational Technology on Teacher Stress and Anxiety: A Literature Review

2021 ◽  
Vol 18 (2) ◽  
pp. 548
Author(s):  
José-María Fernández-Batanero ◽  
Pedro Román-Graván ◽  
Miguel-María Reyes-Rebollo ◽  
Marta Montenegro-Rueda
Keyword(s):  
Systematic Review ◽  
Educational Technology ◽  
Teaching And Learning ◽  
Teaching Practice ◽  
Web Of Science ◽  
Teacher Stress ◽  
Bibliographic Databases ◽  
Technology In The Classroom ◽  
Stress Symptoms ◽  
Meta Analyses

Educational technology has become an increasingly important element for improving the teaching and learning process of students. To achieve these goals, it is essential that teachers have the skills they need to be able to introduce technology into their teaching practice. However, this is often overwhelming and stressful for many of them. The aim of this review was to find out how research on teacher stress and anxiety associated with the use of educational technology was proceeding. A systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines through the following bibliographic databases: PubMed, Web of Science, and Scopus. Sixteen articles were found from the review. The main findings show that teachers present high levels of anxiety or stress due to their use of educational technology in the classroom. Among the conclusions, the need for research on different strategies to prevent the emergence of these anxiety and stress symptoms in teachers stands out.

scholarly journals The value of lncRNAs as prognostic biomarkers on clinical outcomes in osteosarcoma: a meta-analysis

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wenchao Zhang ◽  
Xiaolei Ren ◽  
Lin Qi ◽  
Chenghao Zhang ◽  
Chao Tu ◽  
...  
Keyword(s):  
Web Of Science ◽  
Meta Analysis ◽  
Positive Outcome ◽  
Clinical Applications ◽  
Clinicopathological Features ◽  
Cochrane Library ◽  
Human Osteosarcoma ◽  
Non Coding Rna ◽  
The Cochrane Library ◽  
Long Non Coding Rna

Abstract Background In recent years, emerging studies have demonstrated critical functions and potential clinical applications of long non-coding RNA (lncRNA) in osteosarcoma. To further validate the prognostic value of multiple lncRNAs, we have conducted this updated meta-analysis. Methods Literature retrieval was conducted by searching PubMed, Web of Science and the Cochrane Library (last update by October 2, 2019). A meta-analysis was performed to explore association between lncRNAs expression and overall survival (OS) of osteosarcoma patients. Relationships between lncRNAs expression and other clinicopathological features were also analyzed respectively. Results Overall, 4351 patients from 62 studies were included in this meta-analysis and 25 lncRNAs were identified. Pooled analyses showed that high expression of 14 lncRNAs connoted worse OS, while two lncRNAs were associated with positive outcome. Further, analysis toward osteosarcoma clinicopathologic features demonstrated that overexpression of TUG1 and XIST indicated poor clinical parameters of patients. Conclusions This meta-analysis has elucidated the prognostic potential of 16 lncRNAs in human osteosarcoma. Evidently, desperate expression and functional targets of these lncRNAs offer new approaches for prognosis and therapy of osteosarcoma.

Avascular Osteonecrosis of the Talus: Current Treatment Strategies

2021 ◽  
pp. 107110072110510
Author(s):  
Hanci Zhang ◽  
Amanda N. Fletcher ◽  
Daniel J. Scott ◽  
James Nunley
Keyword(s):  
Risk Factors ◽  
Clinical Diagnosis ◽  
Treatment Strategies ◽  
Core Decompression ◽  
Bone Grafts ◽  
Current Treatment ◽  
Optimal Treatment ◽  
Patient Specific ◽  
Avascular Osteonecrosis ◽  
Current Trends

Avascular osteonecrosis (AVN) of the talus (AVNT) is a painful and challenging clinical diagnosis. AVNT has multiple known risk factors and etiologies and presents at different stages in severity. Given these unique factors, the optimal treatment solution has yet to be determined. Both joint-preserving and joint-sacrificing procedures are available, including core decompression and arthrodeses. Recently, new salvage and replacement techniques have been described including vascularized pedicle bone grafts and total talus replacement using patient-specific prosthesis; however, evidence remains limited. This review examines the current trends AVNT treatment and the emerging data behind these novel techniques.

scholarly journals Resources and Capabilities from Their Very Outset: a Bibliometric Comparison Between Scopus and the Web of Science

2018 ◽  
Vol 10 (4) ◽  
pp. 1
Author(s):  
Mileidy Alvarez-Melgarejo ◽  
Martha L. Torres-Barreto
Keyword(s):  
Web Of Science ◽  
Bibliographic Databases ◽  
Scientific Publications ◽  
Bibliometric Method ◽  
Search Results ◽  
Resources And Capabilities ◽  
New Research ◽  
The Relationship ◽  
The Web

The bibliometric method has proven to be a powerful tool for the analysis of scientific publications, in such a way that allows rating the quality of the knowledge generating process, as well as its impact on firm´s environment. This article presents a comparison between two powerful bibliographic databases in terms of their coverage and the usefulness of their content. The comparison starts with a subject associated to the relationship between resources and capabilities. The outcomes show that the search results differ between both databases. The Web Of Science (WOS), has a greater coverage than SCOPUS has.  It also has a greater impact in terms of most cited authors and publications. The search results in the WOS yield articles from 2001, while Scopus yields articles from 1976, however, some of the latter are inconsistent with the topic being searched. The analysis points to a lack of studies regarding resources as foundations of firm´s capabilities; as a result, new research on this field is suggested.

scholarly journals A new database of the references on international clinical practice guidelines: a facility for the evaluation of clinical research

2019 ◽  
Vol 122 (2) ◽  
pp. 1221-1235 ◽  
Author(s):  
Magnus Eriksson ◽  
Annika Billhult ◽  
Tommy Billhult ◽  
Elena Pallari ◽  
Grant Lewison
Keyword(s):  
Clinical Practice ◽  
Clinical Research ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Web Of Science ◽  
Research Impact ◽  
Clinical Impact ◽  
Bibliographic Databases ◽  
Research Publications ◽  
Research Level

AbstractAlthough there are now several bibliographic databases of research publications, such as Google Scholar, Pubmed, Scopus, and the Web of Science (WoS), and some also include counts of citations, there is at present no similarly comprehensive database of the rapidly growing number of clinical practice guidelines (CPGs), with their references, which sometimes number in the hundreds. CPGs have been shown to be useful for the evaluation of clinical (as opposed to basic) biomedical research, which often suffers from relatively low counts of citations in the serial literature. The objectives were to introduce a new citation database, clinical impact®, and demonstrate how it can be used to evaluate research impact of clinical research publications by exploring the characteristics of CPG citations of two sets of papers, as well as show temporal variation of clinical impact® and the WoS. The paper includes the methodology used to retain the data and also the rationale adopted to achieve data quality. The analysis showed that although CPGs tend preferentially to cite papers from their own country, this is not always the case. It also showed that cited papers tend to have a more clinical research level than uncited papers. An analysis of diachronous citations in both clinical impact® and the WoS showed that although the WoS citations showed a decreasing trend after a peak at 2–3 years after publication, this was less clear for CPG citations and a longer timescale would be needed to evaluate their impact on these documents.

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