scholarly journals A Potassium Based Fluorine Containing Bioactive Glass for Use as a Desensitizing Toothpaste

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4327
Author(s):  
Melissa Tiskaya ◽  
David Gillam ◽  
Saroash Shahid ◽  
Robert Hill
Keyword(s):  
Artificial Saliva ◽  
Potassium Oxide ◽  
Ion Release ◽  
Bioactive Glasses ◽  
Dentinal Tubules ◽  
Dentine Hypersensitivity ◽  
Small Peak ◽  
Sodium Glass ◽  
31P Mas Nmr ◽  
Diffraction Patterns

Potassium releasing bioactive glasses (BAGs) may offer improved relief for dentine hypersensitivity compared to conventional sodium containing BAGs by releasing K+ ions for nerve desensitization and occluding dentinal tubules to prevent fluid flow within dentinal tubules. Potassium oxide was substituted for sodium oxide on a molar basis in a fluoride containing BAG used in toothpastes for treating dentine hypersensitivity. The BAG powders were then immersed in an artificial saliva at pH 7 and tris buffer and the pH rise and ion release behavior were characterized by ICP-OES and ISE. The potassium and sodium containing BAGs were characterized by XRD, DSC, FTIR and NMR. Both BAGs presented amorphous diffraction patterns and the glass transition temperature of the potassium glass was higher than that of the sodium glass. The 31P MAS-NMR spectra indicated a peak at 2.7 ppm corresponding to apatite and a small peak at −103 ppm indicated crystallization to fluorapatite. Both BAGs dissolved and formed apatite at similar rates, although the dissolution of the potassium glass was slightly slower and it released less fluoride as a result of partial nanocrystallization to fluorapatite upon quenching. The potassium release from the potassium ions could potentially result in nerve deactivation when used in toothpastes.

scholarly journals Novel Highly Degradable Chloride Containing Bioactive Glasses

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Xiaojing Chen ◽  
Natalia Karpukhina ◽  
Delia S. Brauer ◽  
Robert G. Hill
Keyword(s):  
Chemical Analysis ◽  
Chloride Content ◽  
Tris Buffer ◽  
Silicate Glasses ◽  
Ion Release ◽  
Bioactive Glasses ◽  
Glass Density ◽  
31P Mas Nmr ◽  
First Time

AbstractAddition of CaF2 to a silicate bioactive glass favours formation of fluorapatite, which is less soluble in acidic environment than hydroxyapatite. However, excess CaF2 in the glass is problematic, owing to the formation of crystalline calcium fluoride rather than fluorapatite on immersion. In this paper we investigate chloride as an alternative to fluoride in bioactive silicate glasses and in particular their bioactivity for the first time. Meltderived bioactive glasses based on SiO2-P2O5-CaO-CaCl2 with varying CaCl2 contents were synthesised and characterised by DSC. Chemical analysis of the chloride content was performed by using an ion selective electrode. Glass density was determined using Helium Pycnometry. The glass bioactivity was investigated in Tris buffer. Ion release measurements were carried out by using ICP-OES. The chemical analysis results indicated that the majority of the chloride is retained in the Q2 type silicate glasses during synthesis. Tg and glass density reduced with increasing CaCl2 content. Apatite-like phase formation was confirmed by FITR, XRD and 31P MAS-NMR. The results of the in vitro studies demonstrated that the chloride containing bioactive glasses are highly degradable and form apatite-like phase within three hours in Tris buffer and, therefore, are certainly suitable for use in remineralising toothpastes. The dissolution rate of the glass was found to increase with CaCl2 content. Faster dissolving bioactive glasses may be attractive for more resorbable bone grafts and scaffolds.

scholarly journals In vitro hydroxyapatite formation of a TTCP and DCPA based dentine desensitiser

2020 ◽  
Author(s):  
Tomas Duminis ◽  
Saroash Shahid ◽  
Robert Hill ◽  
David Gillam ◽  
Alessia D’Onofrio
Keyword(s):  
Artificial Saliva ◽  
Sem Analysis ◽  
Tris Buffer ◽  
Resonance Spectroscopy ◽  
Magic Angle ◽  
Apatite Formation ◽  
Dentinal Tubules ◽  
Dentine Hypersensitivity ◽  
Effective Option

AbstractThe objective of this study was to characterise apatite formation ability of a tetra calcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA) based desensitising product, Teethmate™ (TM). Methods: Cylindrical samples of TM were produced and immersed in TRIS buffer and artificial saliva (AS) for selected time periods. This was followed by characterisation of the phases formed using 31P Magic Angle - Nuclear Magnetic Resonance Spectroscopy, X-ray powder diffraction and Fourier-transform infrared spectroscopy. Dentine discs treated with the material were analysed by scanning electron microscopy (SEM) to evaluate crystal shape and tubules occlusion. Results: SEM analysis showed the formation of plate-like crystals occluding the dentinal tubules. Solid-state characterisation analyses showed that TM cement samples immersed in TRIS-buffer (pH: 7.3) formed hydroxyapatite phases within approximately six hours of immersion. HA formation was less rapid for the samples stored in AS (pH: 6.5). Conclusions: This study shows that a TTCP-DCPA based desensitising product (TM) converts to HA in vitro and provides an effective option for the treatment of dentine hypersensitivity.

scholarly journals In vitro hydroxyapatite formation of a TTCP and DCPA based dentine desensitiser

2020 ◽  
Author(s):  
Tomas Duminis ◽  
Saroash Shahid ◽  
Robert Hill ◽  
David Gillam ◽  
Alessia D’Onofrio
Keyword(s):  
Artificial Saliva ◽  
Sem Analysis ◽  
Tris Buffer ◽  
Resonance Spectroscopy ◽  
Magic Angle ◽  
Apatite Formation ◽  
Dentinal Tubules ◽  
Dentine Hypersensitivity ◽  
Effective Option

AbstractThe objective of this study was to characterise apatite formation ability of a tetra calcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA) based desensitising product, TeethmateTM (TM). Methods: Cylindrical samples of TM were produced and immersed in TRIS buffer and artificial saliva (AS) for selected time periods. This was followed by characterisation of the phases formed using 31P Magic Angle - Nuclear Magnetic Resonance Spectroscopy, X-ray powder diffraction and Fourier-transform infrared spectroscopy. Dentine discs treated with the material were analysed by scanning electron microscopy (SEM) to evaluate crystal shape and tubules occlusion. Results: SEM analysis showed the formation of plate-like crystals occluding the dentinal tubules. Solid-state characterisation analyses showed that TM cement samples immersed in TRIS-buffer (pH: 7.3) formed hydroxyapatite phases within approximately six hours of immersion. HA formation was less rapid for the samples stored in AS (pH: 6.5). Conclusions: This study shows that a TTCP-DCPA based desensitising product (TM) converts to HA in vitro and provides an effective option for the treatment of dentine hypersensitivity.

scholarly journals A Comparative Electrochemical and Morphological Investigation on the Behavior of NiCr and CoCr Dental Alloys at Various Temperatures

Metals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 256
Author(s):  
Florentina Golgovici ◽  
Mariana Prodana ◽  
Florentina Gina Ionascu ◽  
Ioana Demetrescu
Keyword(s):  
Low Temperatures ◽  
Artificial Saliva ◽  
Electrochemical Stability ◽  
Morphological Investigation ◽  
Dental Alloys ◽  
Ion Release ◽  
Icp Ms ◽  
Different Temperatures ◽  
Good Concordance ◽  
Increasing Temperature

The purpose of our study is to compare the behavior of two reprocessed dental alloys (NiCr and CoCr) at different temperatures considering the idea that food and drinks in the oral cavity create various compositions at different pH levels; the novelty is the investigation of temperature effect on corrosion parameters and ion release of dental alloys. Electrochemical stability was studied together with morphology, elemental composition and ions release determination. The results obtained are in good concordance: electrochemistry studies reveal that the corrosion rate is increasing by increasing the temperature. From SEM coupled with EDS, the oxide film formed on the surface of the alloys is stable at low temperatures and a trend to break after 310K. ICP-MS results evidence that in accordance with increasing temperature, the quantities of ions released from the alloys immersed in artificial saliva also increase, though they still remain small, less than 20 ppm.

scholarly journals THE EFFECT OF LACTIC ACID AND ARTIFICIAL SALIVA SOLUTION IMMERSION TO THE RELEASE OF CALCIUM IONS ON BIOACTIVE RESIN

2021 ◽  
Vol 6 (2) ◽  
pp. 190
Author(s):  
Dewi Puspitasari ◽  
Nurah Tajjalia ◽  
Diana Wibowo ◽  
Agung Satria Wardhana
Keyword(s):  
Lactic Acid ◽  
Acid Solution ◽  
Calcium Ions ◽  
Calcium Ion ◽  
Artificial Saliva ◽  
Distilled Water ◽  
Acid Condition ◽  
Ion Release ◽  
Lactic Acid Solution ◽  
Solution Increase

Background: Bioactive resin can release calcium ions when contact with solution media, even in acid condition. In the oral cavity, pH may change into acid condition due to the metabolic results of Streptococcus mutans. The bacteria metabolize carbohydrates into organic acids, one of which is lactic acid. Purpose: Analyze the effect of lactic acid solution and artificial saliva on the number of the release of calcium ions of bioactive resin. Methods: Forty-two specimens (diameter 15 mm x thickness 1 mm; n= 7/group fabricated with Activa™ Bioactive Restorative (Pulpdent). The specimens that meet the criteria were divided into 6 groups. The specimen was immersed for 1 and 7 days in the incubator at 37oC. The number of calcium ion release is measured using titration method. Results: Two Way Anova test and Post Hoc Bonferonni test showed there were significant differences among all group for lactic acid 1 day (4.040 ± 0.360) µg, artificial saliva 1 day (0.640 ± 0.338) µg, distilled water 1 day (1.040 ± 0.504) µg, lactic acid 7 days (5.400 ± 0.312), artificial saliva 7 days (1.640 ± 0.215) µg, distilled water 7 days (3.520± 0.356 µg). Conclusion: There was an influence of lactic acid and artificial saliva on the number of calcium ion releases of bioactive resin. Immersion of bioactive resin in the lactic acid solution increase the calcium ion releases and artificial saliva decrease the calcium ion release compared to distilled water. Keywords: artificial saliva, bioactive resin, calcium ion release, lactic acid

scholarly journals “COMPARATIVE EVALUATION OF EFFECT ON DENTINAL TUBULE OCCLUSION BY THREE DIFFERENT DESENSITIZING DENTIFICES: A SEM STUDY”

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Aman Mallick ◽  
Gaurav Malhotra ◽  
Pradeep Shukla ◽  
Prerna Kataria ◽  
C. S Joshi
Keyword(s):  
Strontium Chloride ◽  
Dentinal Tubule ◽  
Dentinal Tubules ◽  
Dentine Hypersensitivity ◽  
Study Results ◽  
Sem Study ◽  
Group 3 ◽  
Group 2 ◽  
Tubule Occlusion

Introduction: Dentine hypersensitivity (DH) occurs on exposed dentine and is dependent on the patency of dentinal tubules. This study compared the effectiveness of toothpaste containing Strontium Chloride, Novamine, Pro-Arginine in occluding dentine tubules along with comparision of those. Materials and Method: 45 freshly extracted teeth were randomly divided (15 each) into 3 groups: Group 1 15 Teeth treated with toothpaste containing Strontium Chloride. Group 2 15 Teeth treated with toothpaste containing Novamine Group 3 15 Teeth treated with toothpaste containing Pro-Arginine. Each specimen was brushed with the dentifrice slurries and examined under SCM. Result: The mean of occluded dentinal tubules on the dentin surface after brushing with three dentifrices were significant among them Pro-arginine group showed maximum occlusion. Conclusion: The present in vitro SEM study results revealed that:  All the experimental agents– Strontium chloride, novamin, Pro- Argenine were effective in occluding dentinal tubules & the percentage (%) of occluded tubules was found to be highest for Pro- Argenine as compared to the other groups. Keywords: SCM, DH

scholarly journals New Bactericide Orthodonthic Archwire: NiTi with Silver Nanoparticles

Metals ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 702
Author(s):  
F. Javier Gil ◽  
Eduardo Espinar-Escalona ◽  
Nuria Clusellas ◽  
Javier Fernandez-Bozal ◽  
Montserrat Artes-Ribas ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Martensitic Transformation ◽  
Inductively Coupled Plasma ◽  
Artificial Saliva ◽  
Bacterial Strains ◽  
Ion Release ◽  
Critical Temperatures ◽  
Nickel Ion ◽  
Bacteria Culture ◽  
Nanoparticles Of Silver

A potential new bactericide treatment for NiTi orthodontic archwires based in the electrodeposition of silver nanoparticles on the surface was studied. Twenty-five archwires were treated by electrodeposition, obtaining nanoparticles of silver embedded on the archwire surface. These were evaluated in order to investigate the possible changes on the superelastic characteristics (critical temperatures and stresses), the nickel ion release, and the bacteria culture behavior. The chemical composition was analyzed by Energy Dispersive X-Ray Spectroscopy-microanalysis; the singular temperatures of the martensitic transformation were obtained by a flow calorimeter. Induced martensitic transformation stresses were obtained by mechanical testing apparatus. Nickel ion release was analyzed by inductively coupled plasma-mass spectrometry (ICP-MS) equipment using artificial saliva solution at 37 °C. Bacterial tests were studied with the most used oral bacterial strains: Streptococcus sanguinis and Lactobacillus salivarius. NiTi samples were immersed in bacterial suspensions for 2 h at 37 °C. Adhered bacteria were separated and seeded on agar plates: Tood-Hewitt (TH) and Man-Rogosa-Sharpe (MRS) for S. sanguinis and for L.salivarius, respectively. These were then incubated at 37 °C for 1 day and the colonies were analyzed. The results showed that the transformation temperatures and the critical stresses have not statistically significant differences. Likewise, nickel ion release at different immersion times in saliva at 37 °C does not present changes between the original and treated with silver nanoparticles archwires. Bacteria culture results showed that the reduction of the bacteria due to the presence to the nanoparticles of silver is higher than 90%. Consequently, the new treatment with nanoparticles of silver could be a good candidate as bactericidic orthodontic archwire.

scholarly journals Metal ion release from silver soldering and laser welding caused by different types of mouthwash

2014 ◽  
Vol 85 (4) ◽  
pp. 665-672 ◽  
Author(s):  
Ayse Tuygun Erdogan ◽  
Didem Nalbantgil ◽  
Feyza Ulkur ◽  
Fikrettin Sahin
Keyword(s):  
Laser Welding ◽  
Metal Ions ◽  
Sodium Fluoride ◽  
Inductively Coupled Plasma ◽  
Metal Ion ◽  
Artificial Saliva ◽  
Ion Release ◽  
Sem Images ◽  
Metal Ion Release ◽  
Group Comparisons

ABSTRACT Objective:  To compare metal ion release from samples welded with silver soldering and laser welding when immersed into mouthwashes with different ingredients. Materials and Methods:  A total of 72 samples were prepared: 36 laser welded and 36 silver soldered. Four samples were chosen from each subgroup to study the morphologic changes on their surfaces via scanning electron microscopy (SEM). Each group was further divided into four groups where the samples were submerged into mouthwash containing sodium fluoride (NaF), mouthwash containing sodium fluoride + alcohol (NaF + alcohol), mouthwash containing chlorhexidine (CHX), or artificial saliva (AS) for 24 hours and removed thereafter. Subsequently, the metal ion release from the samples was measured with inductively coupled plasma mass spectrometry (ICP-MS). The metal ion release among the solutions and the welding methods were compared. The Kruskal-Wallis and analysis of variance (ANOVA) tests were used for the group comparisons, and post hoc Dunn multiple comparison test was utilized for the two group comparisons. Results:  The level of metal ion release from samples of silver soldering was higher than from samples of laser welding. Furthermore, greater amounts of nickel, chrome, and iron were released from silver soldering. With regard to the mouthwash solutions, the lowest amounts of metal ions were released in CHX, and the highest amounts of metal ions were released in NaF + alcohol. SEM images were in accord with these findings. Conclusions:  The laser welding should be preferred over silver soldering. CHX can be recommended for patients who have welded appliances for orthodontic reasons.

Ion Release and Galvanic Corrosion of Different Orthodontic Brackets and Wires in Artificial Saliva

2017 ◽  
Vol 18 (3) ◽  
pp. 222-227 ◽  
Author(s):  
Soodeh Tahmasbi ◽  
Tahereh Sheikh ◽  
Yasamin B Hemmati
Keyword(s):  
Galvanic Corrosion ◽  
Artificial Saliva ◽  
Potential Difference ◽  
Orthodontic Brackets ◽  
Saturated Calomel Reference Electrode ◽  
Ion Release ◽  
Microscopic Evaluation ◽  
Two Samples ◽  
Significant Difference ◽  
The Mean

ABSTRACT Introduction To investigate the galvanic corrosion of brackets manufactured by four different companies coupled with stainless steel (SS) or nickel–titanium (NiTi) wires in an artificial saliva solution. Materials and methods A total of 24 mandibular central incisor Roth brackets of four different manufacturers (American Orthodontics, Dentaurum, Shinye, ORJ) were used in this experimental study. These brackets were immersed in artificial saliva along with SS or NiTi orthodontic wires (0.016”, round) for 28 days. The electric potential difference of each bracket/ wire coupled with a saturated calomel reference electrode was measured via a voltmeter and recorded constantly. Corrosion rate (CR) was calculated, and release of ions was measured with an atomic absorption spectrometer. Stereomicroscope was used to evaluate all samples. Then, samples with corrosion were further assessed by scanning electron microscope and energydispersive X-ray spectroscopy. Two-way analysis of variance was used to analyze data. Results Among ions evaluated, release of nickel ions from Shinye brackets was significantly higher than that of other brackets. The mean potential difference was significantly lower in specimens containing a couple of Shinye brackets and SS wire compared with other specimens. No significant difference was observed in the mean CR of various groups (p>0.05). Microscopic evaluation showed corrosion in two samples only: Shinye bracket coupled with SS wire and American Orthodontics bracket coupled with NiTi wire. Conclusion Shinye brackets coupled with SS wire showed more susceptibility to galvanic corrosion. There were no significant differences among specimens in terms of the CR or released ions except the release of Ni ions, which was higher in Shinye brackets. How to cite this article Tahmasbi S, Sheikh T, Hemmati YB. Ion Release and Galvanic Corrosion of Different Orthodontic Brackets and Wires in Artificial Saliva. J Contemp Dent Pract 2017;18(3):222-227.

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