scholarly journals Mass Spectrometric Identification of Antimicrobial Peptides from Medicinal Seeds

Molecules ◽  
2021 ◽  
Vol 26 (23) ◽  
pp. 7304
Author(s):  
Tessa B. Moyer ◽  
Amanda M. Brechbill ◽  
Leslie M. Hicks
Keyword(s):  
Medicinal Plants ◽  
Antimicrobial Peptides ◽  
Disulfide Bonds ◽  
Trifolium Pratense ◽  
Red Clover ◽  
In Silico Analysis ◽  
Lipid Transfer ◽  
Bioactive Natural Products ◽  
Antibacterial Screening ◽  
Traditional Medicinal Plants

Traditional medicinal plants contain a variety of bioactive natural products including cysteine-rich (Cys-rich) antimicrobial peptides (AMPs). Cys-rich AMPs are often crosslinked by multiple disulfide bonds which increase their resistance to chemical and enzymatic degradation. However, this class of molecules is relatively underexplored. Herein, in silico analysis predicted 80–100 Cys-rich AMPs per species from three edible traditional medicinal plants: Linum usitatissimum (flax), Trifolium pratense (red clover), and Sesamum indicum (sesame). Bottom-up proteomic analysis of seed peptide extracts revealed direct evidence for the translation of 3–10 Cys-rich AMPs per species, including lipid transfer proteins, defensins, α-hairpinins, and snakins. Negative activity revealed by antibacterial screening highlights the importance of employing a multi-pronged approach for AMP discovery. Further, this study demonstrates that flax, red clover, and sesame are promising sources for further AMP discovery and characterization.

Ethnobiological survey of Maasai traditional medicinal plants

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
E Makule ◽  
J Heilmann ◽  
B Kraus
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicinal Plants

Extraction and Phytochemicals Determination of Traditional Medicinal Plants for Anti-microbial Susceptibility Test

2020 ◽  
Vol 2020 ◽  
Author(s):  
Firew Admasu
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Traditional Medicine ◽  
Crude Extract ◽  
Susceptibility Test ◽  
Plant Sample ◽  
Traditional Medicinal Plants ◽  
Traditional Health Care ◽  
Susceptibility Tests

Abstract: The study were conducted at Dilla University, College of Natural Sciences, Biological Sciences laboratories. Background: Ethiopia is a country with many ethnic groups, cultures and beliefs which in turn have contributed to the high diversity of traditional health care knowledge and practices of traditional medicine from local growth plants, animals and minerals for various physical and mental disorders of human and livestock population that passed from generation to generation for centuries. Medicinal plants contributors to pharmaceutical, agricultural and food industries in the world. The use of medicinal plants in the industrialized societies has been traced to extraction and development of several drugs used in order to heel some diseases having inhibiting effect against pathogenic microorganism. Objective: The main objective of this study was Extraction and Phytochemicals determination of traditional medicinal plants for anti microbial susceptibility test. Methodology: The extraction and identification of some phytochemicals crude compound which used for antimicrobial susceptibility test from plant sample such as Ocimum lamiifolium (OL), Croton maerosth (Cm) and Ruta chalepesis (RC) were conducted. Plant samples are collected, powdered using mortal and pistil and extracted using ethanol and some susceptibility tests were performed to identify some phytochemicals compound. Result: The main result of Antimicrobial activity test showed that the crude extract of OL has the highest zone of inhibition. The highest yield of crude extract (38.21%) was obtained from Croton maerosth (CM) which followed by Ruta chalepesis (RC) (32.43%). However, the lowest yield (28.37%) was obtained from Oscpmum lamifolium (OL). Conclusion: Traditional Medicine is used by many people to managing numerous conditions; it’s accessible and effective on antimicrobial activity. Therefore, it plays a significant role by reducing life-threatening ailments of people and other animals.

NAMING OF BASOTHO MEDICINAL PLANTS: SEMANTIC CONNECTION TO THEIR REMEDIES

2015 ◽  
Vol 25 (1) ◽  
Author(s):  
R Possa ◽  
P Khotso
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Indigenous Knowledge ◽  
Future Generation ◽  
Speech Community ◽  
Traditional Medicines ◽  
Traditional Medicinal Plants ◽  
The Future ◽  
Economic Sphere ◽  
Medical Plants

The indigenous knowledge of the Basotho makes it simple for this speech community to name their traditional medicinal plants in such a way that they are meaningful; this could also be viewed as an empowerment technique, especially in the economic sphere. Their medicinal plants names seem to be idiomatic and to express certain philosophies of the Basotho society. Creativity is observable in this kind of naming, and many names allude to the kind of remedy that is associated with the medicinal plant. It is therefore the interest of this paper to consider the names of medical plants among the Basotho whose names allude to the remedy they provide. The names of Sesotho medicinal plants and the reasoning of the Basotho in general behind the name and the use of each medicinal plant will be discussed in this article. This paper will further preserve and promote the use of Basotho traditional medicines for the future generation.

Pemanfaatan Tumbuhan Obat Tradisional oleh Etnis Sangihe di Kepulauan Sangihe Bagian Selatan, Sulawesi Utara (The Usage of Traditional Medicinal Plants by Sangihe Ethnic in the Southern Sangihe Islands, North Sulawesi)

2018 ◽  
Vol 8 (2) ◽  
pp. 45
Author(s):  
Chrisye Yustitia Pelokang ◽  
Roni Koneri ◽  
Deidy Katili
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Plant Species ◽  
Structured Interviews ◽  
Active Components ◽  
Plant Materials ◽  
Medical Practitioners ◽  
North Sulawesi ◽  
Traditional Medicinal Plants ◽  
Plant Families

Abstrak Tumbuhan obat merupakan tumbuhan yang menghasilkan satu atau lebih komponen aktif yang dipercaya oleh penduduk berkhasiat obat sehingga dimanfaatkan dalam pengobatan tradisional. Penelitian ini bertujuan untuk mengidentifikasi dan mengkaji spesies tumbuhan yang digunakan sebagai obat tradisional oleh Etnis Sangihe di Kepulauan Sangihe bagian Selatan, Sulawesi Utara. Pengambilan data dilakukan melalui wawancara terstruktur  yang diajukan kepada pengobat tradisional. Hasil penelitian menunjukkan adanya 38 spesies dari 25 famili tumbuhan yang dimanfaatkan sebagai tumbuhan obat oleh Etnis Sangihe bagian Selatan. Herba merupakan habitus tumbuhan yang banyak dimanfaatkan untuk bahan pengobatan. Bagian tumbuhan yang paling banyak digunakan sebagai obat yaitu daun. Cara pengolahan yang paling banyak digunakan adalah direbus. Jenis penyakit yang dapat diobati dengan tumbuhan obat sebanyak 22 jenis penyakit. Kata kunci: tumbuhan obat, obat tradisional, habitus, Kepulauan Sangihe Bagian Selatan Abstract             Medicinal plants are plants that produce one or more active components that are believed by local people as medicinal plants for traditional medicine practices. This study aimed to identify and to assess the plant species that used as traditional medicine by the Sangihe Ethnic in the Southern Sangihe Islands, North Sulawesi. Data collection was conducted by structured interviews to the indigenous medical practitioners. The results showed that 38 plant species from 25 plant families were used as medicinal plants by the Southern Sangihe Ethnic people. Herbs were plant habitus that were widely used for medicinal ingredients. The leaves were widely used as medicinal plant materials. Boiling was the most processing method for preparing medicinal herbs. There were 22 types of diseases that could be treated using medicinal plants. Keywords: medicinal plants, traditional medicine, habitus, Southern Sangihe Islands

Comparisons of Floral Response of Seed Lots of Dollard Red Clover, Trifolium pratense L. 1

Crop Science ◽  
1965 ◽  
Vol 5 (5) ◽  
pp. 425-428 ◽  
Author(s):  
R. J. Bula ◽  
R. G. May ◽  
C. S. Garrison ◽  
C. M. Rincker ◽  
J. G. Dean
Keyword(s):  
Trifolium Pratense ◽  
Red Clover ◽  
Trifolium Pratense L

New Drug Discovery from Medicinal Plants and Phytoconstituents for Depressive Disorders

2019 ◽  
Vol 18 (2) ◽  
pp. 92-102 ◽  
Author(s):  
Fatma Tuğçe Gürağaç Dereli ◽  
Mert Ilhan ◽  
Esra Küpeli Akkol
Keyword(s):  
Medicinal Plants ◽  
Depressive Disorders ◽  
Living Standards ◽  
Side Effect Profile ◽  
Active Components ◽  
Synthetic Drugs ◽  
Traditional Medicinal Plants ◽  
Antidepressant Effects ◽  
Life Threatening ◽  
Culinary Herbs

Background & Objective: Depression, a risk factor for several serious diseases, is a highly prevalent and life-threatening psychiatric disorder. It can affect the individual’s position in life and reduce the living standards. The research on the use of medicinal plants in treating this disease has increased enormously because of the possible low rehabilitation rate and side effects of available synthetic drugs, such as sexual dysfunction, nausea, fatigue, insomnia, hypersomnia, and weight gain.Conclusion:Therefore, this review aimed to draw attention to the antidepressant effects of culinary herbs and traditional medicinal plants and their active components, thereby promoting their use in the development of more potent antidepressants with improved side effect profile.

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