Palygorskite-Based Organic–Inorganic Hybrid Nanocomposite for Enhanced Antibacterial Activities

A synergistic antibacterial strategy is effective in enhancing the antibacterial efficacy of a single antibacterial material. Plant essential oils (PEOs) are safe antibacterial agents. However, some of their characteristics such as intense aroma, volatility, and poor thermal stability limit their antibacterial activity and applications. In this paper, five kinds of PEOs were incorporated onto ZnO/palygorskite (ZnO/PAL) nanoparticles by a simple adsorption process to form organic–inorganic nanocomposites (PEOs/ZnO/PAL) with excellent antibacterial properties. TEM and SEM analyses demonstrated that ZnO nanoparticles uniformly anchored onto the surface of rod-like PAL, and that the structure of ZnO/PAL maintained after the incorporation of ZnO nanoparticles and PEOs. It was found that carvacrol/ZnO/palygorskite (CAR/ZnO/PAL) exhibited higher antibacterial activities than other PEOs/ZnO/PAL nanocomposites, with minimum inhibitory concentration (MIC) values of 0.5 mg/mL and 1.5 mg/mL against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively. Moreover, the antibacterial efficiency of CAR/ZnO/PAL nanocomposites was superior to that of ZnO/PAL and pure CAR, demonstrating the synergistic effect that occurs in the combined system. PAL serving as a carrier for the combination of organic PEOs and ZnO nanoparticles is an effective strategy for enhanced, clay-based, organic–inorganic hybrid antibacterial nanocomposites.

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Antibacterial Properties of CdO Nano-Cubes Synthesized via Microwave Method

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.829.294 ◽

2013 ◽

Vol 829 ◽

pp. 294-298 ◽

Cited By ~ 3

Author(s):

Mehrdad Rashidzadeh

Keyword(s):

Structural Information ◽

Cadmium Oxide ◽

Antibacterial Properties ◽

Antibacterial Activities ◽

Raw Material ◽

X Ray Diffraction ◽

Gram Negative ◽

E Coli ◽

Oxidation Reduction ◽

Cdo Nanoparticles

High purity Cadmium (Cd) metal was used as raw material and placed in a microwave susceptor. an evaporation/oxidation process occurs under exposure to microwave in less than 2 minutes. Then, Evaporated cadmium reacted with oxygen and cadmium oxide was collected on the inner surface of a glassy container that was placed a few centimeters above the susceptor. Morphological and structural information of As-synthesized CdO nanopowder, were investigated via SEM and X-ray diffraction (XRD) spectroscopy. The antibacterial activities of different concentration of the CdO nanoparticles were tested by treating Escherichia coli (Gram negative) cultures with CdO nanoparticles. The Study indicates that cadmium oxide nanoparticles show effective antibacterial activity toward the gram-negative bacterium E. coli. Electrochemical properties of as-synthesized powder were investigated via linear and two vertex cyclic voltammetery in the presence of ethanol, a pair of Oxidation/reduction peaks were achieved.

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Electrospun Nanofibrous Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) With Antibacterial Activity

10.31487/j.jbem.2019.01.02 ◽

2019 ◽

pp. 1-7

Author(s):

Samir Abbad Andaloussi ◽

Davy Louis Versace ◽

Estelle Renard ◽

Etienne Dessauw ◽

Valerie Langlois

Keyword(s):

Antiradical Activity ◽

Layered Materials ◽

Antibacterial Activities ◽

E Coli ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion ◽

Electron Microscopy Analysis ◽

Microscopy Analysis ◽

Antibacterial Material ◽

Scanning Electron

Elaboration of electrospun nanofibrous poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV)-based mats was implemented through two routes to obtain antibacterial material containing carvacrol, a phenolic compound extracted from essential oils. The first strategy relied on a direct blend of PHBHV and carvacrol/-cyclodextrin inclusion complexes, PHBHV (carvCD-IC), while the second approach implied the elaboration of multilayered scaffold via the introduction of poly(β-CD-epichlorohydrin), PolyCD. The PolyCD/carv-based mat was electrospun between two hydrophobic PHBHV mats. Scanning Electron Microscopy analysis of mats showed uniform and beadless fibers. The three layered materials [PHBHV-(PolyCD/carv)-PHBHV] is sufficient to ensure optimal antiradical activity (RSA of 88.6%) and exhibit interesting antibacterial activities against E. coli and S. aureus.

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Synthesis of quinoline attached-furan-2(3H)-ones having anti-inflammatory and antibacterial properties with reduced gastro-intestinal toxicity and lipid peroxidation

Journal of the Serbian Chemical Society ◽

10.2298/jsc110131142a ◽

2011 ◽

Vol 76 (12) ◽

pp. 1617-1626 ◽

Cited By ~ 6

Author(s):

Mohammad Alam ◽

Priya Sarkar ◽

Asif Husain ◽

Akranth Marella ◽

M.S. Zaman ◽

...

Keyword(s):

Lipid Peroxidation ◽

Phosphorus Oxychloride ◽

Antibacterial Properties ◽

Antibacterial Activities ◽

Dimethyl Formamide ◽

Significant Activity ◽

Acylation Reaction ◽

Reaction Conditions ◽

E Coli ◽

Anti Inflammatory

A series of 3-[2-chloroquinolin-3-yl)methylene]-5-aryl-furan-2(3H)-ones {3(a-p)} were synthesized. The required 3-(substitutedbenzoyl) propionic acids {2(a-d)} were prepared under Friedal Craft acylation reaction conditions. The substituted 2-chloroquinoline-3-carbaldehydes {1(a-d)} were synthesized by reaction of substitutedphenylethanone-oxime with phosphorus oxychloride in presence of dimethyl formamide using the Vilsmeir Haack reaction method. These compounds were screened for their anti-inflammatory and antibacterial activities along with their ulcerogenic and lipid peroxidation potentials. The compounds that showed significant anti-inflammatory activity were further screened for their analgesic activity. The compounds were less toxic in terms of ulcerogenicity as compared to a standard, which was also supported by lipid peroxidation studies. The antibacterial activities were performed against Staphylococcus aureus and Escherichia coli. Compounds 3f, 3n and 3o showed significant activity against both S. aureus and E. coli having an MIC value of 6.25?g mL-1.

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Enhanced Photocatalytic Antibacterial Properties of TiO2 Nanospheres with Rutile/Anatase Heterophase Junctions and the Archival Paper Protection Application

Nanomaterials ◽

10.3390/nano11102585 ◽

2021 ◽

Vol 11 (10) ◽

pp. 2585

Author(s):

Yingying Qin ◽

Xinyu Wang ◽

Pengyuan Qiu ◽

Jian Tian

Keyword(s):

Antibacterial Properties ◽

Antibacterial Activities ◽

Bet Surface Area ◽

High Yield ◽

Potential Candidate ◽

Radical Oxygen Species ◽

E Coli ◽

Simulated Solar Light ◽

Antibacterial Performance ◽

Chemical Annealing

TiO2 has been generally studied for photocatalytic sterilization, but its antibacterial activities are limited. Herein, TiO2 nanospheres with rutile/anatase heterophase junctions are prepared by a wet chemical/annealing method. The large BET surface area and pore size are beneficial for the absorption of bacteria. The rutile/anatase heterojunctions narrow the bandgap, which enhances light absorption. The rutile/anatase heterojunctions also efficiently promote the photogenerated carriers’ separation, finally producing a high yield of radical oxygen species, such as •O2– and •OH, to sterilize bacteria. As a consequence, the obtained TiO2 nanospheres with rutile/anatase heterojunctions present an improved antibacterial performance against E. coli (98%) within 3 h of simulated solar light irradiation, exceeding that of TiO2 nanospheres without annealing (amorphous) and TiO2 nanospheres annealing at 350 and 550 °C (pure anatase). Furthermore, we design a photocatalytic antibacterial spray to protect the file paper. Our study reveals that the TiO2 nanospheres with rutile/anatase heterojunctions are a potential candidate for maintaining the durability of paper in the process of archival protection.

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Comparative Study of Physicochemical and Antibacterial Properties of ZnO Nanoparticles Prepared by Laser Ablation of Zn Target in Water and Air

10.20944/preprints201812.0125.v1 ◽

2018 ◽

Cited By ~ 1

Author(s):

Ekaterina A. Gavrilenko ◽

Daria A. Goncharova ◽

Ivan N. Lapin ◽

Anna L. Nemoikina ◽

Valery A. Svetlichnyi ◽

...

Keyword(s):

Lactic Acid ◽

Zno Nanoparticles ◽

Biomedical Applications ◽

Antibacterial Properties ◽

Pulsed Laser ◽

Wound Dressings ◽

E Coli ◽

Nanosecond Pulsed Laser ◽

Bactericidal Properties ◽

Biodegradable Poly

Here, we report on ZnO nanoparticles (NPs) generated by nanosecond pulsed laser (Nd:YAG, 1064 nm) through ablation of metallic Zn target in water and air and their comparative analysis as potential nanomaterials for biomedical applications. The prepared nanomaterials were carefully characterized in terms of their structure, composition, morphology and defects. It was found that in addition to the main wurtzite ZnO phase, which is conventionally prepared and reported by others, the sample laser-generated in air also contained some amount of monoclinic zinc hydroxynitrate. Both nanomaterials were then used to modify model wound dressings based on biodegradable poly-L-lactic acid. The as-prepared model dressings were tested as biomedical materials with bactericidal properties towards S. aureus and E. coli strains. The advantages of the NPs prepared in air over their counterparts generated in water found in this work are discussed.   

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Antibacterial Activity of Endophytic Fungi from Sembukan (Paederia foetida L.) Leaves

Science & Technology Indonesia ◽

10.26554/sti.2021.6.3.189-195 ◽

2021 ◽

Vol 6 (3) ◽

pp. 189-195

Author(s):

Hary Widjajanti ◽

Christina Vivid Handayani ◽

Elisa Nurnawati

Keyword(s):

Antibacterial Activity ◽

Secondary Metabolites ◽

Endophytic Fungi ◽

Antimicrobial Agents ◽

Antibacterial Properties ◽

Antibacterial Activities ◽

In Vitro Tests ◽

E Coli ◽

Paederia Foetida

The antibiotic resistance of phatogenic bacteria has become a serious health problem and has encouraged the search for novel and effective antimicrobial metabolites. Meanwhile, endophytic fungi have great potential as a natural source for antimicrobial agents. The endophytic fungi that live in plant tissue produces secondary metabolites which potentially act as an antibacterial compound. The isolation of fungi for antibacterial sources reduces the large amount of plant as a source of antibacterial agents. Hence, this study aims to obtain endophytic fungi isolates from Paederia foetida L. that are capable of producing secondary metabolites as antibacterial, carry out in vitro tests to verify the antibacterial properties of secondary metabolites of the Paederia foetida L. endophytic fungi, and identify the potential of Paederia foetida L. endophytic fungi in producing antibacterial compounds. The antibacterial activity was tested against Escherichia coli ATCC8739 and Staphylococcus aureus ATCC6538 while seven isolates of endophytic fungi that potentially produced antibacterial were obtained from Sembukan (P. foetida L.). The results showed that antibacterial activities of SL1, SL4 and SL6 secondary metabolites against S. aureus ATCC6538 and E. coli ATCC8739 were moderate to strong activities. Furthermore, the Minimum Inhibition Concentration (MIC) of secondary metabolites extract of SL1 against S. aureus ATCC6538 value was 250 ????g/mL while the values of MIC extract of SL4 against S. aureus ATCC6538 and E. coli ATCC8739 were 125 ????g/mL and 250 ????g/mL respectively and MIC extract of SL6 against E. coli ATCC8739 value was 125 ????g/mL. The secondary metabolites extract of SL1 isolate were alkaloid and tannin, SL4 were phenolic and alkaloid while SL6 isolate were alkaloid and terpenoid. Hence, endophytic fungi SL1 isolate was identified as Fusarium sp., SL4 as Dematophora sp., and SL6 isolate as Acremonium sp.

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Comparative Study of Physicochemical and Antibacterial Properties of ZnO Nanoparticles Prepared by Laser Ablation of Zn Target in Water and Air

Materials ◽

10.3390/ma12010186 ◽

2019 ◽

Vol 12 (1) ◽

pp. 186 ◽

Cited By ~ 23

Author(s):

Ekaterina A. Gavrilenko ◽

Daria A. Goncharova ◽

Ivan N. Lapin ◽

Anna L. Nemoykina ◽

Valery A. Svetlichnyi ◽

...

Keyword(s):

Lactic Acid ◽

Zno Nanoparticles ◽

Biomedical Applications ◽

Antibacterial Properties ◽

Pulsed Laser ◽

Wound Dressings ◽

E Coli ◽

Nanosecond Pulsed Laser ◽

Bactericidal Properties ◽

Biodegradable Poly

Here, we report on ZnO nanoparticles (NPs) generated by nanosecond pulsed laser (Nd:YAG, 1064 nm) through ablation of metallic Zn target in water and air and their comparative analysis as potential nanomaterials for biomedical applications. The prepared nanomaterials were carefully characterized in terms of their structure, composition, morphology and defects. It was found that in addition to the main wurtzite ZnO phase, which is conventionally prepared and reported by others, the sample laser generated in air also contained some amount of monoclinic zinc hydroxynitrate. Both nanomaterials were then used to modify model wound dressings based on biodegradable poly l-lactic acid. The as-prepared model dressings were tested as biomedical materials with bactericidal properties towards S. aureus and E. coli strains. The advantages of the NPs prepared in air over their counterparts generated in water found in this work are discussed.

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SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL EVALUATION OF SOME NOVEL BENZIMIDAZOLE DERIVATIVES BEARING HYDRAZONE MOIETY

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10s4.21328 ◽

2017 ◽

Vol 10 (16) ◽

pp. 1

Author(s):

Jayanta Sarma ◽

Gurvinder Singh ◽

Mukta Gupta ◽

Reena Gupta ◽

Bhupinder Kapoor

Keyword(s):

Antibacterial Properties ◽

Antimicrobial Properties ◽

Aromatic Aldehydes ◽

Antibacterial Activities ◽

Antimicrobial Activities ◽

Benzimidazole Derivatives ◽

E Coli ◽

Antimicrobial Evaluation ◽

Antibacterial Potential

Objective: The synthesis of novel benzimidazole-hydrazone derivatives has been carried out based on the previous findings that both these pharmacophores possess potent antimicrobial activities. The antibacterial properties of synthesized derivatives were screened against both Gram-positive and Gram-negative bacteria.Methods: O-phenylenediamine on condensation with substituted aromatic acids in polyphosphoric acid gave benzimidazole nucleus which on reaction with ethyl chloroacetate and hydrazine hydrate in two different steps resulted in the formation of substituted acetohydrazides. The targeted compounds 6a-l were synthesized by reaction of substituted acetohydrazides with aromatic aldehydes and screened for their antibacterial potential by cup-plate method.Results: The synthesized benzimidazole-hydrazones exhibited moderate to strong antibacterial activities against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. The compounds 6a-6f were found to be most effective against S. aureus, E. coli, and P. aeruginosa. Among all the synthesized compounds, the zone of inhibition of 6f in highest concentration, i.e., 100 μg/ml were found to be >31 mm against all the stains of bacteria.Conclusion: The antibacterial results revealed that the synthetized derivatives have significant antimicrobial properties and further structure activity relationship studies may develop more potent and less toxic molecules.

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An ultrasonic technology for production of antibacterial nanomaterials and their coating on textiles

Beilstein Journal of Nanotechnology ◽

10.3762/bjnano.5.62 ◽

2014 ◽

Vol 5 ◽

pp. 532-536 ◽

Cited By ~ 9

Author(s):

Anna V Abramova ◽

Vladimir O Abramov ◽

Aharon Gedanken ◽

Ilana Perelshtein ◽

Vadim M Bayazitov

Keyword(s):

Zno Nanoparticles ◽

Antibacterial Properties ◽

Ultrasonic Waves ◽

Simultaneous Application ◽

Power Ultrasound ◽

E Coli ◽

High Power Ultrasound ◽

Ultrasonic Technology ◽

Electrical Discharge In Water ◽

Very High

A method for the production of antibacterial ZnO nanoparticles has been developed. The technique combines passing an electric current with simultaneous application of ultrasonic waves. By using high-power ultrasound a cavitation zone is created between two zinc electrodes. This leads to the possibility to create a spatial electrical discharge in water. Creation of such discharge leads to the depletion of the electrodes and the formation of ZnO nanoparticles, which demonstrate antibacterial properties. At the end of this reaction the suspension of ZnO nanoparticles is transported to a specially developed ultrasonic reactor, in which the nanoparticles are deposited on the textile. The nanoparticles are embedded into the fibres by the cavitation jets, which are formed by asymmetrically collapsing bubbles in the presence of a solid surface and are directed towards the surface of textile at very high velocities. Fabrics coated with ZnO nanoparticles by using the developed method showed good antibacterial activity against E. coli.

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Antibacterial Activities of Biosynthesized ZnO Nanoparticles Using Leaf and Fruit Extracts of Neolamarckia cadamba

Journal of Nanoscience and Nanotechnology ◽

10.1166/jnn.2021.19538 ◽

2021 ◽

Vol 21 (12) ◽

pp. 6168-6182

Author(s):

Saee Gharpure ◽

Rachana Yadwade ◽

Shuana Mehmood ◽

Balaprasad Ankamwar

Keyword(s):

Antibacterial Activity ◽

Zno Nanoparticles ◽

Leaf Extract ◽

Antibacterial Properties ◽

Fruit Extract ◽

E Coli ◽

Fruit Extracts ◽

Before And After ◽

Micro Organisms ◽

Antibacterial Potential

Zinc oxide nanoparticles have been biosynthesized with the help of Neolamarckia cadamba leaf and fruit extracts. ZnO nanoparticles were tested for antibacterial activity before and after calcination against Gram positive (Staphylococcus aureus, Bacillus subtilis) as well as Gram negative micro-organisms (Escherichia coli, Pseudomonas aeruginosa) within the concentration range 0.625–10 mg/mL with the help of well diffusion technique. Higher antibacterial potential has been observed in ZnO nanoparticles synthesized using leaf extract in comparison with those synthesized using fruit extract. Increased antibacterial activity was observed before calcination as compared to after calcination. ZnO synthesized using leaf extract were observed to show significant antibacterial potential against E. coli, S. aureus along with P. aeruginosa before calcination as well as against E. coli after calcination. Similarly, ZnO nanoparticles synthesized using fruit extract exhibited antibacterial activity against E. coli and P. aeruginosa before calcination and against E. coli after calcination. Both the ZnO nanoparticles before and after calcination did not show any antibacterial activity against B. subtilis. Thus, ZnO nanoparticles can serve a dual purpose by its application as an antibacterial agent against susceptible micro-organisms as well as biocompatible carrier system for drug delivery applications in case of non-antibacterial properties by virtue of its inertness as well as easy disposal.

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