scholarly journals Facial Fabrication of Large-Scale SERS-Active Substrate Based on Self-Assembled Monolayer of Silver Nanoparticles on CTAB-Modified Silicon for Analytical Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3250
Author(s):  
Juanjuan Guo ◽  
Yang Xu ◽  
Caili Fu ◽  
Longhua Guo
Keyword(s):  
Single Molecule ◽  
Large Scale ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Self Assembled Monolayer ◽  
Single Molecule Level ◽  
Analytical Technique ◽  
Relative Standard ◽  
Surface Enhanced Raman

Surface-enhanced Raman spectroscopy (SERS) has been proven to be a promising analytical technique with sensitivity at the single-molecule level. However, one of the key problems preventing its real-world application lies in the great challenges that are encountered in the preparation of large-scale, reproducible, and highly sensitive SERS-active substrates. In this work, a new strategy is developed to fabricate an Ag collide SERS substrate by using cetyltrimethylammonium bromide (CTAB) as a connection agent. The developed SERS substrate can be developed on a large scale and is highly efficient, and it has high-density “hot spots” that enhance the yield enormously. We employed 4-methylbenzenethiol(4-MBT) as the SERS probe due to the strong Ag–S linkage. The SERS enhancement factor (EF) was calculated to be ~2.6 × 106. The efficacy of the proposed substrate is demonstrated for the detection of malachite green (MG) as an example. The limit of detection (LOD) for the MG assay is brought down to 1.0 × 10−11 M, and the relative standard deviation (RSD) for the intensity of the main Raman vibration modes (1620, 1038 cm−1) is less than 20%.

scholarly journals Cascaded microsphere-coupled surface-enhanced Raman spectroscopy (CMS-SERS) for ultrasensitive trace-detection

Nanophotonics ◽  
2022 ◽  
Vol 0 (0) ◽  
Author(s):  
Yanlin Mi ◽  
Yinzhou Yan ◽  
Mengyuan Wang ◽  
Lixue Yang ◽  
Jing He ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Trace Detection ◽  
Excitation Light ◽  
Analytical Technique ◽  
Nano Structures ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Abstract Surface-enhanced Raman spectroscopy (SERS) has been widely investigated and employed as a powerful optical analytical technique providing fingerprint vibrational information of molecules with high sensitivity and resolution. In addition to metallic nanostructure, dielectric micro-/nano-structures with extraordinary optical manipulation properties have demonstrated capability in enhanced Raman scattering with ultralow energy losses. Here we report a facile cascaded structure composed of a large microsphere (LMS) and a small microsphere array with Ag nanoparticles as a novel hybrid SERS substrate, for the first time. The cascaded microsphere-coupled SERS substrate provides a platform to increase the molecular concentration, boost the intensity of localized excitation light, and direct the far-field emission, for giant Raman enhancement. It demonstrates the maximum enhancement factor of Raman intensity greater than 108 for the limit of detection down to 10−11 M of 4-nitrothiphenol molecules in aqueous solution. The present work inspires a novel strategy to fabricate cascaded dielectric/metallic micro-/nano-structures superior to traditional SERS substrates towards practical applications in cost-effective and ultrahigh-sensitive trace-detection.

scholarly journals Heterostructured CuO@ZnO@Ag biomimetic setaria as wettability-switchable difunctional SERS substrate for trace pesticide and DNA detections

Nanophotonics ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Chuanshen Han ◽  
Yisheng Wei ◽  
Fengcai Lei ◽  
Shulong Zhao ◽  
Yumeng Wang ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Raman Scattering ◽  
Single Molecule ◽  
Time Domain ◽  
Deoxyribonucleic Acid ◽  
Limit Of Detection ◽  
Sers Substrate ◽  
Single Molecule Level ◽  
Relative Standard ◽  
Finite Different Time Domain

Abstract Wettability modification is an effective way in tailoring hotspots in surface Raman scattering (SERS) nowadays. However, due to the theoretical contradiction between hydrophobic and hydrophilic strategies, opposite views are usually put forward in building SERS structures. To realize the integration of hydrophobicity and hydrophilia in the same substrate, a wettability-switchable SERS architecture composed of heterostructured CuO@ZnO@Ag biomimetic nano Setaria (NS) has been designed and prepared in this paper. Experimentally, the structure shows impressive SERS performance under both hydrophobic and hydrophilic states. The limit of detection approaches even to single-molecule level and the lowest relative standard deviation is only ca 9.8%. Finite-different time-domain simulations and experimental analyses were systemically made to unearth the mechanism deep behind. Besides, owing to fine quantifiability, the CuO@ZnO@Ag NS shows promising potential in the detection of trace pesticide and deoxyribonucleic acid. This work provides a new idea for integrating the strategies of ‘concentration’ and ‘decentralization’, endowing SERS structure with wider application, and is also meaningful for other surface sciences.

scholarly journals Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments

2020 ◽  
Vol 11 (18) ◽  
pp. 4563-4577 ◽  
Author(s):  
Ana Isabel Pérez-Jiménez ◽  
Danya Lyu ◽  
Zhixuan Lu ◽  
Guokun Liu ◽  
Bin Ren
Keyword(s):  
Raman Spectroscopy ◽  
Single Molecule ◽  
Surface Enhanced Raman Spectroscopy ◽  
Direct Identification ◽  
Molecular Fingerprints ◽  
Single Molecule Level ◽  
Trade Offs ◽  
Target Analytes ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopy technique with sensitivity down to the single molecule level that provides fine molecular fingerprints, allowing for direct identification of target analytes.

scholarly journals Preparation of Hydrophobic Film by Electrospinning for Rapid SERS Detection of Trace Triazophos

Sensors ◽  
2020 ◽  
Vol 20 (15) ◽  
pp. 4120
Author(s):  
Fei Shao ◽  
Jiaying Cao ◽  
Ye Ying ◽  
Ying Liu ◽  
Dan Wang ◽  
...  
Keyword(s):  
Hot Spots ◽  
Large Scale ◽  
Limit Of Detection ◽  
Small Region ◽  
Sers Substrate ◽  
Ag Nps ◽  
Electrospinning Technique ◽  
Heterocyclic Molecules ◽  
Surface Enhanced Raman ◽  
Sers Detection

For real application, it is an urgent demand to fabricate stable and flexible surface-enhanced Raman scattering (SERS) substrates with high enhancement factors in a large-scale and facile way. Herein, by using the electrospinning technique, a hydrophobic and flexible poly(styrene-co-butadiene) (SB) fibrous membrane is obtained, which is beneficial for modification of silver nanoparticles (Ag NPs) colloid in a small region and then formation of more “hot spots” by drying; the final SERS substrate is designated as Ag/SB. Hydrophobic Ag/SB can efficiently capture heterocyclic molecules into the vicinity of hot spots of Ag NPs. Such Ag/SB films are used to quantitatively detect trace triazophos residue on fruit peels or in the juice, and the limit of detection (LOD) of 2.5 × 10−8 M is achieved. Ag/SB films possess a capability to resist heat. As a case, 6-mercaptopurine (6MP) that just barely dissolves in 90 °C water is picked for conducting Ag/SB-film-based experiments.

scholarly journals Gold Nanoparticles with Different Particle Sizes for the Quantitative Determination of Chlorpyrifos Residues in Soil by SERS

2019 ◽  
Vol 20 (11) ◽  
pp. 2817 ◽  
Author(s):  
Yong He ◽  
Shupei Xiao ◽  
Tao Dong ◽  
Pengcheng Nie
Keyword(s):  
Gold Nanoparticles ◽  
Limit Of Detection ◽  
Soil Surface ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Least Squares Regression ◽  
Simple Method ◽  
Good Linear ◽  
Relative Standard

Chlorpyrifos (CPF) is widely used in the prevention and control of crop pests and diseases in agriculture. However, the irrational utilization of pesticides not only causes environmental pollution but also threatens human health. Compared with the conventional techniques for the determination of pesticides in soil, surface-enhanced Raman spectroscopy (SERS) has shown great potential in ultrasensitive and chemical analysis. Therefore, this paper reported a simple method for synthesizing gold nanoparticles (AuNPs) with different sizes used as a SERS substrate for the determination of CPF residues in soil for the first time. The results showed that there was a good linear correlation between the SERS characteristic peak intensity of CPF and particle size of the AuNPs with an R2 of 0.9973. Moreover, the prepared AuNPs performed great ultrasensitivity, reproducibility and chemical stability, and the limit of detection (LOD) of the CPF was found to be as low as 10 μg/L. Furthermore, the concentrations ranging from 0.01 to 10 mg/L were easily observed by SERS with the prepared AuNPs and the SERS intensity showed a good linear relationship with an R2 of 0.985. The determination coefficient (Rp2) reached 0.977 for CPF prediction using the partial least squares regression (PLSR) model and the LOD of CPF residues in soil was found to be as low as 0.025 mg/kg. The relative standard deviation (RSD) was less than 3.69% and the recovery ranged from 97.5 to 103.3%. In summary, this simple method for AuNPs fabrication with ultrasensitivity and reproducibility confirms that the SERS is highly promising for the determination of soil pesticide residues.

scholarly journals Liquid Surface-Enhanced Raman Spectroscopy (SERS) Sensor-Based Au-Ag Colloidal Nanoparticles for Easy and Rapid Detection of Deltamethrin Pesticide in Brewed Tea

Crystals ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 24
Author(s):  
Affi Nur Hidayah ◽  
Djoko Triyono ◽  
Yuliati Herbani ◽  
Rosari Saleh
Keyword(s):  
Raman Spectroscopy ◽  
Liquid Surface ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Ease Of Use ◽  
Raman Signal ◽  
Colloidal Nanoparticles ◽  
Sers Substrate ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Deltamethrin pesticides can cause inflammation, nephrotoxicity and hepatotoxicity as well as affect the activity of antioxidant enzymes in tissues. As a result of this concern, there is a rising focus on the development of fast and reliable pesticide residue testing to minimise potential risks to humans. The goal of this study is to use Au-Ag colloid nanoparticles as liquid surface-enhanced Raman spectroscopy (SERS) to improve the Raman signal in the detection of deltamethrin pesticide in a brewed tea. The liquid SERS system is fascinating to study due to its ease of use and its unlikeliness to cause several phenomena, such as photo-bleaching, combustion, sublimation and even photo-catalysis, which can interfere with the Raman signal, as shown in the SERS substrate. Our liquid SERS system is simpler than previous liquid SERS systems that have been reported. We performed the detection of pesticide analyte directly on brewed tea, without diluting it with ethanol or centrifuging it. Femtosecond laser-induced photo-reduction was employed to synthesise the liquid SERS of Au, Au-Ag, and Ag colloidal nanoparticles. The SERS was utilised to detect deltamethrin pesticide in brewed tea. The result showed that liquid SERS-based Ag NPs significantly enhance the Raman signal of pesticides compared with liquid SERS-based Au NPs and Au-Ag Nanoalloys. The maximum residue limits (MRLs) in tea in Indonesia are set at 10 ppm. Therefore, this method was also utilised to detect and improve, to 0.01 ppm, the deltamethrin pesticide Limit of Detection (LOD).

scholarly journals Comparative Performance of Citrate, Borohydride, Hydroxylamine and β-Cyclodextrin Silver Sols for Detecting Ibuprofen and Caffeine Pollutants by Means of Surface-Enhanced Raman Spectroscopy

Nanomaterials ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2339
Author(s):  
Michele Lemos de Souza ◽  
Juan Carlos Otero ◽  
Isabel López-Tocón
Keyword(s):  
Raman Spectroscopy ◽  
Emerging Contaminants ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Molar Ratio ◽  
Sers Substrate ◽  
Comparative Performance ◽  
Sers Signal ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

The detection of emerging contaminants in the aquatic environment, such as ibuprofen and caffeine, was studied by means of surface-enhanced Raman spectroscopy (SERS) using Ag nanoparticles (AgNPs) synthesized with β-cyclodextrin (βCD) as a reducing agent. The effect on the SERS signal of different molar ratios of Ag+/βCD in the synthesis route and the aging process of AgNPs were investigated by using trans-cinnamic as a test molecule. The SERS effectiveness of these β-cyclodextrin colloids (Ag@βCD) was also checked and compared with that of other silver sols usually employed in SERS synthesized by using other reducing agents such as citrate, borohydride and hydroxylamine. All the synthesized SERS substrates were characterized by different techniques. The experimental results indicate that Ag@βCD with the more diluted Ag+/βCD molar ratio showed the best SERS signal, enabling detection at trace concentrations of 0.5 µM in the case of trans-cinnamic acid. The Ag@βCD sols also showed the best sensitivity for detecting ibuprofen and caffeine, reaching the lowest limit of detection (0.1 mM). The proposed synthetic route for Ag@βCD sols provides an improved SERS substrate for detecting organic pollutants with better performance than other standard silver sols.

scholarly journals Biomimetic synthesis of Ag-coated glasswing butterfly arrays as ultra-sensitive SERS substrates for efficient trace detection of pesticides

2019 ◽  
Vol 10 ◽  
pp. 578-588 ◽  
Author(s):  
Guochao Shi ◽  
Mingli Wang ◽  
Yanying Zhu ◽  
Yuhong Wang ◽  
Xiaoya Yan ◽  
...  
Keyword(s):  
High Performance ◽  
Limit Of Detection ◽  
Biomimetic Synthesis ◽  
Substantial Contribution ◽  
Sers Substrate ◽  
Trace Detection ◽  
Entire Area ◽  
Long Term Stability ◽  
Relative Standard ◽  
Surface Enhanced Raman

In this work, we report a biomimetic synthesis route of 3D Ag nanofilm/glasswing butterfly wing hybrids (Ag-G.b.) by magnetron sputtering technology. The 3D surface-enhanced Raman scattering (SERS) substrate is fabricated from an original chitin-based nanostructure, which serves as a bio-scaffold for Ag nanofilms to be coated on. The novel crisscrossing plate-like nanostructures of 3D Ag-G.b. nanohybrids with thick Ag nanofilms provide a substantial contribution to SERS enhancement. Measuring the SERS performance with crystal violet (CV), the Ag-G.b. nanohybrids with the sputtering time of 20 min (Ag-G.b.-20) shows the highest enhancement performance with an enhancement factor (EF) of up to 2.96 × 107. The limit of detection (LOD) for CV was as low as 10−11 M, demonstrating the ultrahigh sensitivity of the Ag-G.b.-20 substrate. In addition, the Ag-G.b.-20 substrate has an outstanding reproducibility across the entire area with the maximum value of relative standard deviation (RSD) of less than 10.78%. The nanohybrids also exhibit a long-term stability regarding Raman enhancement, as suggested by a duration stability test over a period of 60 days. Importantly, the high-performance Ag-G.b.-20 substrate is further applied as an ultra-sensitive SERS platform for the trace detection of acephate, showing its great potential application in biochemical sensing and food security.

scholarly journals Flexible and Reusable Ag Coated TiO2 Nanotube Arrays for Highly Sensitive SERS Detection of Formaldehyde

Molecules ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 1199 ◽  
Author(s):  
Tong Zhu ◽  
Hang Wang ◽  
Libin Zang ◽  
Sila Jin ◽  
Shuang Guo ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Catalytic Performance ◽  
Tio2 Nanotube ◽  
Detection Sensitivity ◽  
Sers Substrate ◽  
Environmental Media ◽  
Sensing Platform ◽  
Surface Enhanced Raman ◽  
Sers Detection

Quantitative analysis of formaldehyde (HCHO, FA), especially at low levels, in various environmental media is of great importance for assessing related environmental and human health risks. A highly efficient and convenient FA detection method based on surface-enhanced Raman spectroscopy (SERS) technology has been developed. This SERS-based method employs a reusable and soft silver-coated TiO2 nanotube array (TNA) material, such as an SERS substrate, which can be used as both a sensing platform and a degradation platform. The Ag-coated TNA exhibits superior detection sensitivity with high reproducibility and stability compared with other SERS substrates. The detection of FA is achieved using the well-known redox reaction of FA with 4-amino-3-hydrazino-5-mercapto-1,2,4-triazole (AHMT) at room temperature. The limit of detection (LOD) for FA is 1.21 × 10−7 M. In addition, the stable catalytic performance of the array allows the degradation and cleaning of the AHMT-FA products adsorbed on the array surface under ultraviolet irradiation, making this material recyclable. This SERS platform displays a real-time monitoring platform that combines the detection and degradation of FA.

scholarly journals Ultra-rapid and highly efficient enrichment of organic pollutants via magnetic mesoporous nanosponge for ultrasensitive nanosensors

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Lingling Zhang ◽  
Yu Guo ◽  
Rui Hao ◽  
Yafei Shi ◽  
Hongjun You ◽  
...  
Keyword(s):  
Organic Pollutants ◽  
Single Molecule ◽  
Cross Sections ◽  
Limit Of Detection ◽  
Detection Sensitivity ◽  
Practical Applications ◽  
Single Molecule Level ◽  
Surface Enhanced Raman ◽  
Low Sensitivity ◽  
Enrichment Strategy

AbstractCurrently, owing to the single-molecule-level sensitivity and highly informative spectroscopic characteristics, surface-enhanced Raman scattering (SERS) is regarded as the most direct and effective detection technique. However, SERS still faces several challenges in its practical applications, such as the complex matrix interferences, and low sensitivity to the molecules of intrinsic small cross-sections or weak affinity to the surface of metals. Here, we show an enrichment-typed sensing strategy with both excellent selectivity and ultrahigh detection sensitivity based on a powerful porous composite material, called mesoporous nanosponge. The nanosponge consists of porous β-cyclodextrin polymers immobilized with magnetic NPs, demonstrating remarkable capability of effective and fast removal of organic micropollutants, e.g., ~90% removal efficiency within ~1 min, and an enrichment factor up to ~103. By means of this current enrichment strategy, the limit of detection for typical organic pollutants can be significantly improved by 2~3 orders of magnitude. Consequently, the current enrichment strategy is proved to be applicable in a variety of fields for portable and fast detection, such as Raman and fluorescent sensing.

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