scholarly journals Electrospun Polyvinyl Alcohol Loaded with Phytotherapeutic Agents for Wound Healing Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3336
Author(s):  
Diana Serbezeanu ◽  
Alexandra Bargan ◽  
Mihaela Homocianu ◽  
Magdalena Aflori ◽  
Cristina Mihaela Rîmbu ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Polyvinyl Alcohol ◽  
Vinyl Alcohol ◽  
Moisture Sorption ◽  
Salvia Officinalis ◽  
Poly Vinyl Alcohol ◽  
Total Phenolic ◽  
Thymus Vulgaris ◽  
Electrospinning Technique ◽  
Phenolic Contents

In this paper, hydroalcoholic solutions of Thymus vulgaris, Salvia officinalis folium, and Hyperici herba were used in combination with poly (vinyl alcohol) with the aim of developing novel poly (vinyl alcohol)-based nanofiber mats loaded with phytotherapeutic agents via the electrospinning technique. The chemical structure and morphology of the polymeric nanofibers were investigated using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The addition of Thymus vulgaris, Salvia officinalis folium, and Hyperici herba extracts to the pure polyvinyl alcohol fibers led to changes in the morphology of the fibers and a reduction in the fibers’ diameter, from 0.1798 µm in the case of pure polyvinyl alcohol to 0.1672, 0.1425, and 0.1369 µm in the case of polyvinyl alcohol loaded with Thymus vulgaris, Salvia officinalis folium, and Hyperici herba, respectively. The adapted Folin–Ciocalteu (FC) method, which was used to determine the total phenolic contents, revealed that the samples of PVA–Hyperici herba and PVA–Thymus vulgaris had the highest phenol contents, at 13.25 μgGAE/mL and 12.66 μgGAE/mL, respectively. Dynamic water vapor measurements were used in order to investigate the moisture sorption and desorption behavior of the developed electrospun materials. The antimicrobial behavior of these products was also evaluated. Disk diffusion assay studies with Escherichia coli, Staphylococcus aureus, and Methicillin-resistant Staphylococcus aureus were conducted on the developed nanofibers in order to quantify their phytotherapeutic potential.

scholarly journals Photoselection of Luminescent Molecules in Anisotropic Media in the Case of Two-Photon Excitation. Part II. Experimental Studies of Hoechst 33342 in Stretched Polyvinyl alcohol) Films

1996 ◽  
Vol 51 (9) ◽  
pp. 1037-1041 ◽  
Author(s):  
A. Kawski ◽  
Z. Gryczyński ◽  
I. Gryczyński ◽  
J. R. Lakowicz ◽  
G. Piszczek
Keyword(s):  
Polyvinyl Alcohol ◽  
Vinyl Alcohol ◽  
Experimental Studies ◽  
Poly Vinyl Alcohol ◽  
Hoechst 33342 ◽  
Emission Anisotropy ◽  
Two Photon ◽  
Photon Excitation ◽  
Polyvinyl Alcohol Films ◽  
Two Photon Excitation

Abstract It was found by investigating dichroism and emission anisotropy in the case of one-and two-photon excitation of Hoechst 33342 [bis-benzimide,2,5'-bi-1H-benzimidazole, 2'-(4-ethoxyphenyl)-5-5(4-methyl-1-piperazinyl)] in stretched poly(vinyl alcohol) (PVA) films, that the absorption and fluorescence transition moments lie along the long molecular axis of the molecule studied. The slight deviation of the transition moment direction in fluorescence (about 8°) from that in absorption can be due to the incomplete linearity of the Hoechst molecule.

scholarly journals Active Packaging—Poly(Vinyl Alcohol) Films Enriched with Tomato By-Products Extract

Coatings ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 141 ◽  
Author(s):  
Katalin Szabo ◽  
Bernadette-Emoke Teleky ◽  
Laura Mitrea ◽  
Lavinia-Florina Călinoiu ◽  
Gheorghe-Adrian Martău ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Total Phenolic Content ◽  
Food Packaging ◽  
Phenolic Content ◽  
Flow Behavior ◽  
Poly Vinyl Alcohol ◽  
Total Phenolic ◽  
Active Food Packaging ◽  
Film Forming ◽  
By Products

Active films were prepared from poly(vinyl alcohol) (PVA) blended with itaconic acid (Ia), and with chitosan (Ch), enriched with tomato processing by-products extract (TBE) in order to develop new bioactive formulations for food packaging. The effects of two biopolymers (Ch, Ia) and of the incorporated TBE—containing phenolic compounds and carotenoids—were studied regarding the physical and antimicrobial properties of films; in addition, their influence on the total phenolic content, viscosity, and flow behavior on the film-forming solutions was investigated. The results showed increased physical properties (diameter, thickness, density, weight) of the films containing the TBE versus their control. TBE and Ch conferred significant antimicrobial effects to PVA films toward all the tested microorganisms, whereas the best inhibition was registered against S. aureus and P. aeruginosa, with a minimum inhibitory concentration of <0.078 mg DW/mL. The Ia-PVA films also exhibited some antibacterial activity against P. aeruginosa (2.5 mg DW/mL). The total phenolic content of the film-forming solutions presented the highest values for the TBE and Ch-added PVA samples (0.208 mg gallic acid/100 mL film-forming solution). These results suggest that the PVA + Ch film containing TBE can be used for the development of intelligent and active food packaging materials.

Modeling of moisture sorption isotherms of poly(vinyl alcohol)/starch films

2003 ◽  
Vol 89 (14) ◽  
pp. 3874-3881 ◽  
Author(s):  
Baldev Raj ◽  
A. Eugene Raj ◽  
P. Madan ◽  
Siddaramaiah
Keyword(s):  
Vinyl Alcohol ◽  
Sorption Isotherms ◽  
Moisture Sorption ◽  
Poly Vinyl Alcohol ◽  
Moisture Sorption Isotherms ◽  
Starch Films

Substituent Effects on the Luminescence of 2-Substituted 3-Methylquinoxalines in Poly (Vinyl Alcohol) Films*

1991 ◽  
Vol 46 (4) ◽  
pp. 304-306 ◽  
Author(s):  
Z. Gryczyński ◽  
A. Kawski
Keyword(s):  
Polyvinyl Alcohol ◽  
Temperature Dependence ◽  
Vinyl Alcohol ◽  
Substituent Effects ◽  
Quantum Yields ◽  
Poly Vinyl Alcohol ◽  
Band Position ◽  
Fluorescence And Phosphorescence ◽  
Polyvinyl Alcohol Films

Abstract The effect of 2-substitutions (NH2 . O, CH3O, CI. Br) in 3-methylquinoxalines on the fluorescence and phosphorescence band position and intensity at 293 K, and the temperature dependence of their fluorescence and phosphorescence quantum yields were investigated in polyvinyl alcohol) films

Evaluation of Antioxidant Activity and Total Phenols Content in Selected Spices

2017 ◽  
Vol 68 (7) ◽  
pp. 1429-1434 ◽  
Author(s):  
Gabriela Stanciu ◽  
Nicoleta Cristache ◽  
Simona Lupsor ◽  
Simona Dobrinas
Keyword(s):  
Phenolic Content ◽  
Antioxidant Activities ◽  
Ocimum Basilicum ◽  
Extraction Time ◽  
Mentha Piperita ◽  
Total Phenolic ◽  
Thymus Vulgaris ◽  
Total Phenols ◽  
Phenolic Contents ◽  
Polyphenolic Content

The total phenols contents and antioxidant activities of alcoholic extractive solutions of Ocimum basilicum (basil), Thymus vulgaris (thyme), Mentha piperita (mint), Rosmarinus officinalis (rosemary), Sativa officinalis (sage), Artemisia dracunculus (tarragon) and Coriandrum sativum (coriander) were examined using Folin-Ciocalteu method and ACL method, respectively. Extractive alcoholic solutions of above mentioned seven spices were analyzed during a period of five months in order to determine the optimal extraction time when the polyphenolic content was at maximum. The highest total phenolic contents were registered for rosemary (608.37 mg GAE/100 g d.w.), sage (530.66 mg GAE/100g d.w.) and mint (511.87 mg GAE/100g d.w.) In general the optimal extraction time of the total phenolic content was reached after 3 months of maceration, except thyme, tarragon (after two months) and coriander (after one month). The antioxidant capacity ranged between 1410.1 nmols Trolox/g d.w. for rosemary and 4.2560 nmols Trolox/g d.w. for tarragon.

scholarly journals Phenolic Compounds and In Vitro Antibacterial and Antioxidant Activities of Three Tropic Fruits: Persimmon, Guava, and Sweetsop

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Li Fu ◽  
WenQing Lu ◽  
XiaoMin Zhou
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Antioxidant Activities ◽  
Multidrug Resistant ◽  
Total Phenolic ◽  
Food Preservatives ◽  
Phenolic Contents

In our previous study, we have found that persimmon, guava, and sweetsop owned considerably high antioxidant activity and contained high total phenolic contents as well. In order to further supply information on the antibacterial and antioxidant activity of these three tropic fruits, they were extracted by 80% methanol. We then examined the extractions about their phenolic compounds and also studied the extractions and phenolic contents about their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against twelve targeted pathogens including 8 standard strains (Staphylococcus aureus,Bacillus cereus,Staphylococcus epidermidis,Monilia albican,Escherichia coli,Salmonella typhimurium,Shigella flexneri, andPseudomonas aeruginosa) and 4 multidrug-resistant strains (methicillin-resistant Staphylococcus aureus, ESBLs-producingEscherichia coli, carbapenems-resistantPseudomonas aeruginosa, and multidrug-resistantAcinetobacter baumannii), which are common and comprehensive in clinic. We also employed two ways, that is, FRAP and TEAC, to evaluate their antioxidant activities, using ultraviolet and visible spectrophotometer. Our study indicated that the three tropical fruits possessed obvious antioxidant and antibacterial activity, which supported the possibility of developing the fruits into new natural resource food and functional food as well as new natural antimicrobial agent and food preservatives. Moreover, phenolic compounds detected in the fruits could be used as a potential natural antibacterial agent and antioxidant.

Dehydration Sensing of a Polyvinyl Alcohol Film via Plasmonic Nanoparticles

MRS Advances ◽  
2019 ◽  
Vol 4 (5-6) ◽  
pp. 299-304
Author(s):  
Milana O. Lisunova
Keyword(s):  
Refractive Index ◽  
Polyvinyl Alcohol ◽  
Real Time ◽  
Rate Constant ◽  
Vinyl Alcohol ◽  
Plasmonic Nanoparticles ◽  
Poly Vinyl Alcohol ◽  
Dehydration Rate ◽  
Polyvinyl Alcohol Film

ABSTRACTIn situ, real-time monitoring of a dehydration of poly(vinyl alcohol) (PVA) film is researched. The technique based on the incorporation plasmonic nanocages (NCs) between the two identical layers of PVA, (PVA)/NCs/(PVA) film, and its sensitivity to the variation of the refractive index of the surrounding PVA film via desorption water. The dehydration time increases from 180 (s) to 1800 (s) as the content of the PVA in the films increases twice, from (PVA)/NCs/(PVA) to (PVA)2/NCs/(PVA)2. Such effect could be explained by different rate of the molecules desorption from the PVA based films. Specifically, the dehydration rate is of 0.22 (vol% per s) and 0.026 (vol% per s) for (PVA)/NCs/(PVA) and (PVA)2/NCs/(PVA)2 films, respectively. The dehydration rate constant reduces from -50×10-4 (s-1) to -4.3 ×10-4 (s-1) as the content of PVA increases from (PVA)/NCs/(PVA) to (PVA)2/NCs/(PVA)2 films, respectively.

scholarly journals Electrospun Chitosan/Poly (Vinyl Alcohol)/Graphene Oxide Nanofibrous Membrane with Ciprofloxacin Antibiotic Drug for Potential WoundDressing Application

2019 ◽  
Vol 20 (18) ◽  
pp. 4395 ◽  
Author(s):  
Yang ◽  
Zhang ◽  
Zhang
Keyword(s):  
Graphene Oxide ◽  
Drug Release ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Burst Release ◽  
Drug Release Profile ◽  
Electrospinning Technique ◽  
Antibiotic Drugs ◽  
Antibiotic Drug ◽  
Nanofibrous Membranes

In this paper, nanofibrous membranes based on chitosan (CS), poly (vinyl alcohol) (PVA) and graphene oxide (GO) composites, loaded with antibiotic drugs, such as Ciprofloxacin (Cip) and Ciprofloxacin hydrochloride (CipHcl) were prepared via the electrospinning technique. The uniform and defect-free CS/PVA nanofibers were obtained and GO nanosheets, shaping spindle and spherical, were partially embedded into nanofibers. Besides, the antibiotic drugs were effectively loaded into the nanofibers and part of which were absorbed into GO nanosheets. Intriguingly, the release of the drug absorbed in GO nanosheets regulated the drug release profile trend, avoiding the “burst” release of drug at the release initial stage, and the addition of GO slightly improved the drug release ratio. Nanofibrous membranes showed the significantly enhanced antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis after the addition of antibiotic drug. Moreover, the drug-loaded nanofibrous membranes exhibited excellent cytocompatibility with Melanoma cells, indicative to the great potential potential for applications in wound dressing.

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