scholarly journals Large-Scale Fabrication of Nanostructure on Bio-Metallic Substrate for Surface Enhanced Raman and Fluorescence Scattering

Nanomaterials ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 916 ◽  
Author(s):  
Lu ◽  
Zhang ◽  
Jiao ◽  
Guan
Keyword(s):  
Large Scale ◽  
Hierarchical Structures ◽  
Metallic Substrate ◽  
Nano Particles ◽  
Fluorescence Signal ◽  
Dual Mode ◽  
Surface Enhanced Fluorescence ◽  
Relative Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

The integration of surface-enhanced Raman scattering (SERS) and surface-enhanced fluorescence (SEF) has attracted increasing interest and is highly probable to improve the sensitivity and reproducibility of spectroscopic investigations in biomedical fields. In this work, dual-mode SERS and SEF hierarchical structures have been developed on a single bio-metallic substrate. The hierarchical structure was composed of micro-grooves, nano-particles, and nano-ripples. The crystal violet was selected as reporter molecule and both the intensity of Raman and fluorescence signals were enhanced because of the dual-mode SERS−SEF phenomena with enhancement factors (EFs) of 7.85 × 105 and 14.32, respectively. The Raman and fluorescence signals also exhibited good uniformity with the relative standard deviation value of 2.46% and 5.15%, respectively. Moreover, the substrate exhibited high sensitivity with the limits of detection (LOD) as low as 1 × 10−11 mol/L using Raman spectroscopy and 1 × 10−10 mol/L by fluorescence spectroscopy. The combined effect of surface plasmon resonance and “hot spots” induced by the hierarchical laser induced periodical surface structures (LIPSS) was mainly contributed to the enhancement of Raman and fluorescence signal. We propose that the integration of SERS and SEF in a single bio-metallic substrate is promising to improve the sensitivity and reproducibility of detection in biomedical investigations.

Chemical preparation and applications of silver dendrites

2014 ◽  
Vol 68 (10) ◽  
Author(s):  
Li Fu ◽  
Tasnuva Tamanna ◽  
Wen-Jing Hu ◽  
Aimin Yu
Keyword(s):  
Hierarchical Structures ◽  
Surface Enhanced Raman Spectroscopy ◽  
Future Research ◽  
Surface Enhanced Fluorescence ◽  
Preparation Methods ◽  
Practical Applications ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Methods Of Synthesis ◽  
Silver Dendrites

AbstractSilver dendrites have received immense attention because of their fascinating hierarchical structures and unique properties. Depending on the methods of synthesis, Ag dendrites can be implemented in numerous fields. This review summarizes a variety of Ag dendrites preparation techniques. The involved growth mechanisms are investigated in order to control the formation progress more effectively. With regard to the applications, this article mainly focuses on surface enhanced Raman spectroscopy, catalysis, superhydrophobic surface and surface enhanced fluorescence by using Ag dendrites. The remaining issues of the preparation methods, which impede the practical applications of Ag dendrites, are pointed out to enlighten their future research.

A large-scale superhydrophobic surface-enhanced Raman scattering (SERS) platform fabricated via capillary force lithography and assembly of Ag nanocubes for ultratrace molecular sensing

2014 ◽  
Vol 16 (48) ◽  
pp. 26983-26990 ◽  
Author(s):  
Joel Ming Rui Tan ◽  
Justina Jiexin Ruan ◽  
Hiang Kwee Lee ◽  
In Yee Phang ◽  
Xing Yi Ling
Keyword(s):  
Detection Limit ◽  
High Throughput ◽  
Superhydrophobic Surface ◽  
Large Scale ◽  
Molecular Sensing ◽  
M 10 ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Capillary Force Lithography

A high-throughput fabrication of a stable and uniform superhydrophobic SERS platform is demonstrated. It is able to detect trace molecules at ultra-low detection limit of 10−17 M (10 aM) using just 4 μL of analyte solutions.

scholarly journals Large-Scale Fabrication of Ultrasensitive and Uniform Surface-Enhanced Raman Scattering Substrates for the Trace Detection of Pesticides

Nanomaterials ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. 520 ◽  
Author(s):  
Jia Zhu ◽  
Guanzhou Lin ◽  
Meizhang Wu ◽  
Zhuojie Chen ◽  
Peimin Lu ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Large Scale ◽  
Capillary Flow ◽  
Surface Enhanced Raman Scattering ◽  
Ag Nps ◽  
Uniform Size ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Technology transfer from laboratory into practical application needs to meet the demands of economic viability and operational simplicity. This paper reports a simple and convenient strategy to fabricate large-scale and ultrasensitive surface-enhanced Raman scattering (SERS) substrates. In this strategy, no toxic chemicals or sophisticated instruments are required to fabricate the SERS substrates. On one hand, Ag nanoparticles (NPs) with relatively uniform size were synthesized using the modified Tollens method, which employs an ultra-low concentration of Ag+ and excessive amounts of glucose as a reducing agent. On the other hand, when a drop of the colloidal Ag NPs dries on a horizontal solid surface, the droplet becomes ropy, turns into a layered structure under gravity, and hardens. During evaporation, capillary flow was burdened by viscidity resistance from the ropy glucose solution. Thus, the coffee-ring effect is eliminated, leading to a uniform deposition of Ag NPs. With this method, flat Ag NPs-based SERS active films were formed in array-well plates defined by hole-shaped polydimethylsiloxane (PDMS) structures bonded on glass substrates, which were made for convenient detection. The strong SERS activity of these substrates allowed us to reach detection limits down to 10−14 M of Rhodamine 6 G and 10−10 M of thiram (pesticide).

scholarly journals Duplex Surface Enhanced Raman Scattering-Based Lateral Flow Immunosensor for the Low-Level Detection of Antibiotic Residues in Milk

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5249
Author(s):  
Ruiqi Fan ◽  
Shusheng Tang ◽  
Sunlin Luo ◽  
Hu Liu ◽  
Wanjun Zhang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Simultaneous Detection ◽  
Surface Enhanced Raman Scattering ◽  
Lateral Flow ◽  
Antibiotic Residues ◽  
Relative Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Analytical Approaches

A duplex surface enhanced Raman scattering (SERS)-based lateral flow immunosensor was established for the simultaneous detection of two common antibiotic residues including tetracycline and penicillin in milk. The newly synthesized Au@Ag nanoparticles were labeled with different Raman molecules including 5,5-dithiobis-2-nitrobenzoic acid (DTNB) or 4-mercaptobenzoic acid (MBA), followed by the conjugation of anti-tetracycline monoclonal antibody or anti-penicillin receptor, forming two kinds of SERS nanoprobes. The two nanoprobes can recognize tetracycline-BSA and ampicillin-BSA, respectively, which facilitates the simultaneous detection of the two types of antibiotics on a single test line. After optimization, detection limits of tetracycline and penicillin as low as 0.015 ng/mL and 0.010 ng/mL, respectively, were achieved. These values were far below those of most of other documented bio-analytical approaches. Moreover, the spiking test demonstrates an excellent assay accuracy with recoveries of 88.8% to 111.3%, and satisfactory assay precision with relative standard deviation below 16%. Consequently, the results demonstrate that the SERS-based lateral flow immunosensor developed in this study has the advantages of excellent assay sensitivity and remarkable multiplexing capability, thus it will have great application potential in food safety monitoring.

scholarly journals Silver-Nanoparticle-Decorated Gold Nanorod Arrays via Bioinspired Polydopamine Coating as Surface-Enhanced Raman Spectroscopy (SERS) Platforms

Coatings ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 198 ◽  
Author(s):  
Mehmet Yilmaz
Keyword(s):  
Raman Spectroscopy ◽  
Deposition Time ◽  
Surface Enhanced Raman Spectroscopy ◽  
Gold Nanorod ◽  
Nanorod Arrays ◽  
Plasmonic Material ◽  
Relative Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Controlled Deposition

The controlled deposition of nanoparticles onto 3-D nanostructured films is still facing challenges due to the uncontrolled aggregation of colloidal nanoparticles. In the context of this study, a simple yet effective approach is demonstrated to decorate the silver nanoparticles (AgNP) onto the 3-D and anisotropic gold nanorod arrays (GNAs) through a bioinspired polydopamine (PDOP) coating to fabricate surface-enhanced Raman spectroscopy (SERS) platforms. Since the Raman reporter molecules (methylene blue, MB, 10 µM) were not adsorbed directly on the surface of the plasmonic material, a remarkable decrease in SERS signals was detected for the PDOP-coated GNAs (GNA@PDOP) platforms. However, after uniform and well-controlled AgNP decoration on the GNA@PDOP (GNA@PDOP@AgNP), huge enhancement was observed in SERS signals from the resultant platform due to the synergistic action which originated from the interaction of GNAs and AgNPs. I also detected that PDOP deposition time (i.e., PDOP film thickness) is the dominant parameter that determines the SERS activity of the final system and 30 min of PDOP deposition time (i.e., 3 nm of PDOP thickness) is the optimum value to obtain the highest SERS signal. To test the reproducibility of GNA@PDOP@AgNP platforms, relative standard deviation (RSD) values for the characteristic peaks of MB were found to be less than 0.17, demonstrating the acceptable reproducibility all over the proposed platform. This report suggests that GNA@PDOP@AgNP system may be used as a robust platform for practical SERS applications.

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