scholarly journals Growth Benefits of Own Mother’s Milk in Preterm Infants Fed Daily Individualized Fortified Human Milk

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 772 ◽  
Author(s):  
Virginie de Halleux ◽  
Catherine Pieltain ◽  
Thibault Senterre ◽  
Frédéric Studzinski ◽  
Catheline Kessen ◽  
...  

The influence of types of human milk (HM)—raw own mother’s milk (OMM), pasteurized OMM, and donor milk (DM)—was evaluated for growth in premature infants fed exclusively HM with controlled nutritional intakes using daily individualized HM fortification (IHMF). Growth and nutritional intakes were prospectively collected in preterm infants (<32 weeks) fed IHMF and compared in infants fed predominantly (≥75%) OMM and DM. The influence of HM types (raw OMM, pasteurized OMM, and DM) on growth were also evaluated in the whole population. One-hundred and one preterm infants (birth weight 970 ± 255 g, gestational age 27.8 ± 1.9 weeks) were included. Energy (143 ± 8 vs. 141 ± 6 kcal/kg/day; p = 0.15) and protein intakes (4.17 ± 0.15 vs. 4.15 ± 0.14 g/kg/day; p = 0.51) were similar in both groups. Infants receiving predominantly OMM (n = 37), gained significantly more weight (19.8 ± 2.0 vs. 18.2 ± 2.2 g/kg/day; p = 0.002) and length (1.17 ± 0.26 vs. 0.99 ± 0.36 cm/week; p = 0.020) than those fed predominantly DM (n = 33). Stepwise multivariate analysis (n = 101) suggests that raw OMM was the major determinant of growth, contributing 22.7% of weight gain. Length gain was also related to OMM (raw + pasteurized) intakes, explaining 4.0% of length gain. In conclusion, at daily controlled similar protein and energy intakes, OMM had significant beneficial effects on weight and length versus DM in VLBW infants. This difference could be partially explained by the use of raw OMM.

2019 ◽  
Vol 109 (5) ◽  
pp. 959-966 ◽  
Author(s):  
Josefine Fengler ◽  
Matthias Heckmann ◽  
Anja Lange ◽  
Axel Kramer ◽  
Steffen Flessa

2009 ◽  
Vol 28 (6) ◽  
pp. 381-389 ◽  
Author(s):  
Barbara Wheeler

Purpose:Difficulty with breastfeeding is common, and challenges are particularly pronounced for mothers of ill or preterm infants. This study explores the breastfeeding experiences of mothers of these at-risk infants to determine their breastfeeding patterns and to better understand reasons they prematurely stop breastfeeding and/or human-milk feeding (HMF).Design:A qualitative, longitudinal, descriptive design was used.Sample:The sample consisted of 144 mothers whose preterm or ill infants were cared for in either an NICU or an intermediate care nursery in a large central Canadian city; 112 mothers completed data collection to six weeks after their infants were discharged from the hospital.Main Outcome Variable:The main outcome variable was continued breastfeeding or HMF of formerly ill or preterm infants at one and six weeks after their discharge from the hospital.Results:Of infants who were being fed mother’s milk when discharged from the hospital, 71 percent continued to receive at least some mother’s milk at six weeks after discharge. Mothers reported that their own physical and emotional problems, infant health concerns, and lack of time and support were reasons for discontinuing provision of human milk.


1998 ◽  
Vol 44 (4) ◽  
pp. 499-506 ◽  
Author(s):  
Jerry A Peterson ◽  
Margit Hamosh ◽  
Ciaran D Scallan ◽  
Roberto L Ceriani ◽  
Theresa R Henderson ◽  
...  

1997 ◽  
Vol 41 ◽  
pp. 231-231 ◽  
Author(s):  
Marcia M Dos Santos ◽  
Francisco E Martinez ◽  
Vanessa de Moura Sieber ◽  
Marisa M Mussi Pinhata ◽  
Maria LS Felin

2021 ◽  
Vol 5 (1SP) ◽  
pp. 14
Author(s):  
Ariani Dewi Widodo

ABSTRACTBackground: Gut microbiota, a complex ecosystem consisting of abundant microorganisms, plays a role in preterm infants’ immunity, growth, and development. Dysbiosis or disruption of the gut microbiota can precipitate various diseases, such as allergy or autoimmune disorders in premature infants. Purpose: This study aimed to review gut microbiota in preterm infants and its role in supporting the infants’ immunity, growth, and development. Discussion: Bifidobactericeae is the predominant microbiota in GI tract of preterm infants. However, various factors can influence this gut microbiota e.g., genetics, lifestyle of the mothers (smoking, diet, use of antibiotic, obesity), birth mode, type of feeding, and environmental factors. Gut dysbiosis can result in impaired immune system which predisposes the preterm infants to infections, even fatal adverse event. Furthermore, the growth and development might be affected as well as lead to various neurodevelopmental and psychiatric disorders. Human milk is a prebiotic source which can stimulate the growth of Baifidobactericeae and Bacteroidetes. If the human milk is inadequate or unavailable, the recommended interventions for gut dysbiosis in premature infants are probiotics, prebiotics, or both supplementations (synbiotics). The administration of prebiotics and probiotics associates with lower morbidity and death rates in preterm infants, as well as shorter duration of hospital stay and duration to achieve full enteral feeding. Conclusions: Immunity as well as growth and development of preterm infants are affected greatly by gut microbiota The less diverse microbiota in preterm infants’ gut predispose them to various health problems. Hence, this problem should be managed properly, one of which is prebiotic and probiotic supplementation Keywords: Gastrointestinal Microbiome, Premature, Immunity, Growth, Development


2021 ◽  
Vol 11 (9) ◽  
pp. 473
Author(s):  
Tuğçe Tok Kurt ◽  
Çağlar Gökırmaklı ◽  
Zeynep B Guzel-Seydim

Background: Human milk contains the nutrients necessary for the growth and development of babies as it contains essential bioactive components to support the immune system. Galactooligosaccharides which are important indigestible prebiotics, help multiply the growth of beneficial microorganisms selectively and inhibit the growth of the pathogenic organism. The nutrition of the mother is essential since it affects the composition of mother’s milk. Kefir affects the digestive system, lactose intolerance immune system, anti-microbial effects, probiotic and prebiotic features. However, there is no report on how kefir consumption may have effects on composition of mother’s milk. In this aspect, this study aimed to determine the effects of kefir consumption on the carbohydrate profiles of the mother’s milk. Methods: This study started immediately after birth, mothers were fed with 500 ml/day of kefir made from kefir grains for 30 days in the KF group. Mothers who are in the control group (KI) continued their regular diet. Mother’s milk was collected on the 10th, 20th, and 30th day and stored at 4ºC. Carbohydrate profile including GOS was determined using the liquid chromatographic method with the HI-PLEX column.Results: The mean lactose concentrations of mother’s milk who consumed kefir were 4,68; 4,72; 5,89 g/100ml on days 10th, 20th, and 30th, respectively. Glucose concentrations were 0,29; 0,08; 0,21 g/100ml on 10th, 20th, 30th days, respectively. For the mother’s milk samples in the control group, the averages of lactose concentration were 5,42; 5,73; 5,51 g/100ml on days 10th, 20th, and 30th. GOS peaks were specified depending on the rich content of prebiotics. Conclusion: Consumption of authentic kefir may have effect on carbohydrate profile, including GOS of mother’s milk. Keywords: Human milk, kefir, prebiotic, galactooligosaccharides  


2021 ◽  
pp. 265-272
Author(s):  
Michael Obladen

This chapter describes historic steps in feeding techniques and knowledge about the nutritional needs of premature infants. Devices to overcome weak sucking and swallowing were developed from 1851 to 1920: tube feeding by gavage, medicine droppers and pipettes, feeding bottles with air inlet, and beaked spoons for nasal feeding. Indwelling nasogastric tubes were in use from 1951. For alleged safety concerns, postnatal feeding was postponed until a week of starvation was reached in the 1950s and studies showed an association with neurological handicaps. The premature infant’s elevated need for energy, protein, and minerals has been known since 1919. However, nutritional practice lagged behind theoretical knowledge. Concentrated formula was developed in the 1940s, parenteral supplementation in the 1960s, and human milk fortifiers in the 1970s. In the 1990s, necrotizing enterocolitis was found to be more frequent in infants fed formula than in those fed human milk. Recently, probiotics were shown to reduce the risk of necrotizing enterocolitis. Compared to other aspects of neonatal medicine, there is little evidence on how to feed preterm infants.


Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1882
Author(s):  
Paola Roggero ◽  
Nadia Liotto ◽  
Orsola Amato ◽  
Fabio Mosca

Improvements in quality of care have led to a significant reduction in mortality and morbidity in preterm infants, especially very-low-birth-weight (VLBW) infants [...]


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