scholarly journals A Review of A Priori Defined Oxidative Balance Scores Relative to Their Components and Impact on Health Outcomes

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 774 ◽  
Author(s):  
Ángela Hernández-Ruiz ◽  
Belén García-Villanova ◽  
Eduardo Guerra-Hernández ◽  
Pilar Amiano ◽  
Miguel Ruiz-Canela ◽  
...  
Keyword(s):  
Health Outcomes ◽  
A Priori ◽  
Epidemiological Studies ◽  
Dietary Factors ◽  
Colorectal Adenomas ◽  
Adverse Health Outcomes ◽  
Oxidative Balance ◽  
Oxidation Reduction ◽  
Great Heterogeneity ◽  
Definition Of

Oxidative Balance Scores (OBSs) are tools that have emerged to evaluate the global balance of individuals’ oxidation—reduction status. The aim was to compare OBSs available in the literature regarding their characteristics and associations with chronic diseases in epidemiological studies. Studies that developed OBSs were searched in PubMed until August 2018. A total of 21 OBSs were identified. These OBSs presented different scoring schemes and different types of anti- and pro-oxidant components, including dietary factors (dietary intake and/or nutrient biomarkers), lifestyle factors, and medications. Most OBSs were based on over 10 components, and some included only dietary factors. Few considered weighted components in the score. Only three OBSs were validated as potential surrogates of oxidative balance through inflammation and OS-related biomarkers. Notably, all the OBSs were associated—to a varying degree—with a reduced risk of cardiovascular diseases, chronic kidney disease, colorectal adenomas, and different cancer types (colorectal and breast cancer), as well as with all-cause and cancer-related mortality. For other outcomes, e.g., prostate cancer, contradictory results were reported. In summary, there is a great heterogeneity in the definition of OBSs. Most studies are concordant in supporting that excessive OS reflected by a lower OBS has deleterious effects on health. Unified criteria for defining the proper OBSs, valuable to gauge OS-related aspects of the diet and lifestyle that may lead to adverse health outcomes, are needed.

scholarly journals Conceptual and methodological aspects of relations between discrimination and health in epidemiological studies

2012 ◽  
Vol 28 (1) ◽  
pp. 177-183 ◽  
Author(s):  
João Luiz Bastos ◽  
Eduardo Faerstein
Keyword(s):  
Mental Disorders ◽  
Health Outcomes ◽  
Psychosocial Stress ◽  
Epidemiological Studies ◽  
Adverse Health Outcomes ◽  
Epidemiological Surveys ◽  
New Instrument ◽  
Different Types ◽  
Definition Of ◽  
Methodological Aspects

This article addresses conceptual and methodological aspects of the relations between discrimination and health from an epidemiological perspective. Definitions of discrimination and related constructs are reviewed, and the main theories underlying their association with health are presented. Scales developed to assess discrimination are discussed, in conjunction with a new instrument, devised to operationalize the concept in Brazilian epidemiological surveys. As a relatively unpredictable and uncontrollable source of psychosocial stress, discrimination has been consistently associated with adverse health outcomes and behaviors, particularly mental disorders, smoking, and alcohol use. However, progress in the area depends partly on dealing with aspects related to the assessment of the phenomenon, such as the definition of a construct map and simultaneous measurement of different types of discrimination. Research involving these aspects will enhance our understanding of discrimination and its health consequences, thus increasing our ability to reduce its social occurrence.

scholarly journals Patterns of food consumption among vegetarians and non-vegetarians

2014 ◽  
Vol 112 (10) ◽  
pp. 1644-1653 ◽  
Author(s):  
Michael J. Orlich ◽  
Karen Jaceldo-Siegl ◽  
Joan Sabaté ◽  
Jing Fan ◽  
Pramil N. Singh ◽  
...  
Keyword(s):  
Health Outcomes ◽  
Food Consumption ◽  
Dietary Patterns ◽  
A Priori ◽  
Food Group ◽  
Epidemiological Studies ◽  
Consumption Patterns ◽  
Health Study ◽  
Food Groups ◽  
Vegetarian Diets

Vegetarian dietary patterns have been reported to be associated with a number of favourable health outcomes in epidemiological studies, including the Adventist Health Study 2 (AHS-2). Such dietary patterns may vary and need further characterisation regarding foods consumed. The aims of the present study were to characterise and compare the food consumption patterns of several vegetarian and non-vegetarian diets. Dietary intake was measured using an FFQ among more than 89 000 members of the AHS-2 cohort. Vegetarian dietary patterns were defined a priori, based on the absence of certain animal foods in the diet. Foods were categorised into fifty-eight minor food groups comprising seventeen major food groups. The adjusted mean consumption of each food group for the vegetarian dietary patterns was compared with that for the non-vegetarian dietary pattern. Mean consumption was found to differ significantly across the dietary patterns for all food groups. Increased consumption of many plant foods including fruits, vegetables, avocados, non-fried potatoes, whole grains, legumes, soya foods, nuts and seeds was observed among vegetarians. Conversely, reduced consumption of meats, dairy products, eggs, refined grains, added fats, sweets, snack foods and non-water beverages was observed among vegetarians. Thus, although vegetarian dietary patterns in the AHS-2 have been defined based on the absence of animal foods in the diet, they differ greatly with respect to the consumption of many other food groups. These differences in food consumption patterns may be important in helping to explain the association of vegetarian diets with several important health outcomes.

Association between HTLV-1 infection and adverse health outcomes: a systematic review and meta-analysis of epidemiological studies

2020 ◽  
Vol 20 (1) ◽  
pp. 133-143 ◽  
Author(s):  
Gill Schierhout ◽  
Skye McGregor ◽  
Antoine Gessain ◽  
Lloyd Einsiedel ◽  
Marianne Martinello ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Outcomes ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Adverse Health ◽  
Adverse Health Outcomes

Diet-dependent acid load and the risk of colorectal cancer and adenoma: a case–control study

2020 ◽  
pp. 1-8
Author(s):  
Saeede Jafari Nasab ◽  
Pegah Rafiee ◽  
Alireza Bahrami ◽  
Nasim Rezaeimanesh ◽  
Bahram Rashidkhani ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Case Control Study ◽  
Epidemiological Studies ◽  
Case Control ◽  
Dietary Factors ◽  
Colorectal Adenomas ◽  
Newly Diagnosed ◽  
Acid Base Balance ◽  
Acid Load ◽  
Control Study

Abstract Objectives: Colorectal cancer (CRC) is the third and second most prevalent cancer in men and women, respectively. Various epidemiological studies indicated that dietary factors are implicated in the aetiology of CRC and its precursor, colorectal adenomas (CRA). Recently, much attention has been given to the role of acid–base balance in the development of chronic diseases including cancers. Therefore, the aim of the current study is to examine the association of diet-dependent acid load and the risk of CRC and CRA. Design: In this case–control study, potential renal acid load (PRAL) was computed based on dietary intake of participants assessed via a validated FFQ. Negative PRAL values indicated a base-forming potential, while positive values of PRAL implied acid-forming potential of diet. Logistic regression was used to derive OR and 95 % CI after adjusting for confounders. Setting: Tehran, Iran. Participants: A total of 499 participants aged 30–70 years were included in the study (240 hospital controls, 129 newly diagnosed CRC and 130 newly diagnosed CRA). The current study was conducted between December 2016 and September 2018. Results: After adjusting for potential confounders, a higher PRAL was associated with increased odds of CRC and CRA. The highest v. the lowest tertile of PRAL for CRC and CRA was OR 4·82 (95 % CI 2·51–9·25) and OR 2·47 (95 % CI 1·38–4·42), respectively. Conclusions: The findings of the current study suggested that higher diet-dependent acid load is associated with higher risk of CRC and CRA.

The New Geriatric Syndromes

2019 ◽  
Vol 15 (1) ◽  
pp. 33-36
Author(s):  
Animesh Gupta ◽  
Soumya K. Inamadar ◽  
Ashish Goel
Keyword(s):  
Health Outcomes ◽  
Sleep Disorders ◽  
Elderly Population ◽  
Oropharyngeal Dysphagia ◽  
The Elderly ◽  
Present Review ◽  
Social Deficits ◽  
Geriatric Syndromes ◽  
Adverse Health Outcomes ◽  
Clinical Conditions

Geriatric syndromes consist of common clinical conditions affecting the elderly population. They lead to multiple, interacting medical and social deficits that increase the risk of adverse health outcomes, including dependence, institutionalization and also death. Research over the last few decades, in this area of medicine, has led to evolution of newer syndromes that pose a greater challenge to the physician. The present review aims to provide a synopsis of some of the newer syndromes like frailty, osteosarcopenia, sleep disorders and oropharyngeal dysphagia that have emerged in geriatric literature in recent times.

scholarly journals The effects of assisted reproduction technologies on metabolic health and disease

2020 ◽  
Author(s):  
Maria Florencia Heber ◽  
Grażyna Ewa Ptak
Keyword(s):  
Metabolic Syndrome ◽  
Health Outcomes ◽  
Metabolic Diseases ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Postnatal Life ◽  
Metabolic Alterations ◽  
Adverse Health ◽  
Adverse Health Outcomes ◽  
The Individual

Abstract Background The increasing prevalence of metabolic diseases places a substantial burden on human health throughout the world. It is believed that predisposition to metabolic disease starts early in life, a period of great susceptibility to epigenetic reprogramming due to environmental insults. Assisted reproductive technologies (ART), i.e., treatments for infertility, may affect embryo development, resulting in multiple adverse health outcomes in postnatal life. The most frequently observed alteration in ART pregnancies is impaired placental nutrient transfer. Moreover, consequent intrauterine growth restriction and low birth weight followed by catch-up growth can all predict future obesity, insulin resistance, and chronic metabolic diseases. Scope of the review In this review, we have focused on evidence of adverse metabolic alterations associated with ART, which can contribute to the development of chronic adult-onset diseases, such as metabolic syndrome, type 2 diabetes, and cardiovascular disease. Due to high phenotypic plasticity, ART pregnancies can produce both offspring with adverse health outcomes, as well as healthy individuals. We further discuss the sex-specific and age-dependent metabolic alterations reflected in ART offspring, and how the degree of interference of a given ART procedure (from mild to more severe manipulation of the egg) affects the occurrence and degree of offspring alterations. Major conclusions Over the last few years, studies have reported signs of cardiometabolic alterations in ART offspring that are detectable at a young age but that do not appear to constitute a high risk of disease and morbidity per se. These abnormal phenotypes could be early indicators of the development of chronic diseases, including metabolic syndrome, in adulthood. The early detection of metabolic alterations could contribute to preventing the onset of disease in adulthood. Such early interventions may counteract the risk factors and improve the long-term health of the individual.

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