scholarly journals The Association between Serum Magnesium Levels and Depression in an Adult Primary Care Population

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1475 ◽  
Author(s):  
Emily K. Tarleton ◽  
Amanda G. Kennedy ◽  
Gail L. Rose ◽  
Abigail Crocker ◽  
Benjamin Littenberg

Depression is common, places a large burden on the patient, their family and community, and is often difficult to treat. Magnesium supplementation is associated with improved depressive symptoms, but because the mechanism is unknown, it is unclear whether serum magnesium levels act as a biological predictor of the treatment outcome. Therefore, we sought to describe the relationship between serum magnesium and the Patient Health Questionnaire (PHQ, a measure of depression) scores. A cross-sectional analysis of medical records from 3604 adults (mean age 62 years; 42% men) seen in primary care clinics between 2015 and 2018, with at least one completed PHQ were included. The relationship between serum magnesium and depression using univariate analyses showed a significant effect when measured by the PHQ-2 (−0.19 points/mg/dL; 95% CI −0.31, −0.07; P = 0.001) and the PHQ-9 (−0.93 points/mg/dL; 95% CI −1.81, −0.06; P = 0.037). This relationship was strengthened after adjusting for covariates (age, gender, race, time between serum magnesium and PHQ tests, and presence of diabetes and chronic kidney disease) (PHQ-2: −0.25 points/mg/dL; 95% CI −3.33, −0.09; P < 0.001 and PHQ-9: −1.09 95% CI −1.96 −0.21; P = 0.015). For adults seen in primary care, lower serum magnesium levels are associated with depressive symptoms, supporting the use of supplemental magnesium as therapy. Serum magnesium may help identify the biological mechanism of depressive symptoms and identify patients likely to respond to magnesium supplementation.

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1821-1821
Author(s):  
Benjamin Littenberg ◽  
Thomas Ahern ◽  
Emily Tarleton

Abstract Objectives We sought to describe the relationship between serum magnesium, inflammation, and chronic pain in adult primary care patient. Methods We sought to describe this relationship utilizing a cross-sectional analysis of medical records from 5639 adults (mean age 59 years; 42% men) seen in The University of Vermont Medical Center primary care clinics between 2015 and 2018. Patients with at least one serum magnesium level, C-reactive protein (CRP, a measure of inflammation) level, and chronic pain score (self-reported visual analogue scale) were included. Results Univariate analysis confirmed the relationship between serum magnesium and chronic pain (−0.31 points/mg/dL; 95% CI −0.47, −0.14; P &lt; 0.001). However, when serum magnesium and CRP were both included in the model, the relationship with pain is unclear (N = 1345; CI −0.003, 0.002; P = 0.69). Conclusions For adults seen in primary care, lower serum magnesium levels are associated with chronic pain. This inverse relationship is not explained by random noise, including age and gender. The complex relationship between serum magnesium, CRP, and pain is complex requires further exploration. Funding Sources None.


2017 ◽  
Vol 5 (4) ◽  
pp. 441 ◽  
Author(s):  
Joy L Lee ◽  
Sydney M. Dy ◽  
Steven J. Kravet ◽  
Bimal H. Ashar ◽  
Todd Nesson ◽  
...  

Background: The way patients and providers communicate with one another outside of the clinic is changing. However, little is known about primary care provider perspectives and experiences of these changes and whether these provider behaviors correlate with patient satisfaction. This study examines provider patterns of communication with patients outside of the clinic setting via cellphone, email and text messaging and the relationship between communication behaviors and patient satisfaction. Method: Cross-sectional analysis of the association between patient satisfaction scores and a 16-question community survey of 149 Mid-Atlantic primary care providers in community practice was conducted in the year prior to clinic implementation of a new electronic health record system with secure patient-messaging capabilities.Results: Providers who gave patients their email addresses were more likely to communicate with their patients electronically than those who did not. Providers who made their email addresses available to patients also had significantly higher overall satisfaction scores than those who did not, although there were no statistically significant differences in individual satisfaction domains. The use of these cellphone, email and text-messaging were also not found to be associated with patient satisfaction domains.    Conclusions: Provider provision of their email addresses may be an indicator of a stronger relationship with certain patients. This study elucidates the relationship between provider communication behaviors and patient satisfaction. A better understanding of the role of the patient-provider relationship and its role in patient satisfaction may help practices and providers improve their patients’ experience of primary care.  


2013 ◽  
Vol 7 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Veronica A. de Miranda ◽  
Rubens A. Cruz Filho ◽  
Talita Sposito de Oliveira ◽  
Samuel D. Moscavitch ◽  
Hye C. Kang ◽  
...  

2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
Luiz Miguel Santiago ◽  
Maria Castro

Abstract Background The relationship between Cardiovascular Risk (CVR) and the socio-economic family classification (SEC) by the Graffar Index in the Portuguese General and Family Medicine setting is still unknown being an impoirtant Health determinant. SEC interferes with disease perception altering possible health out-comes. Use of specific tools can improve patient’s guidance. So the knowledge of the frequency of estimation of CVR and SEC to understand how they were distributed and related in the Primary Care population of Central Portugal, according to sex, age and place of residence was made using Primary Care generated data. Methods Cross-sectional observational study based on informatics data in anonymity of the population attending all the National Health Service Primary Care Health Units in Central Portugal in December 31, 2019, aged [40–65] years with descriptive and non-parametric analysis at P &lt; 0.05. Results In a Universe of 707 806 CVR was calculated for 27.9%, SEC for 2.5% and both simultaneously for 1.2%. CVR distribution was different by gender (P &lt; 0.001), High/very high risk more prevalent in males. By age group, High/Very high CVR was more prevalent in those over 60 years of age (P &lt; 0.001) and if residing in the southern and more in-land locations presenting a higher risk (P &lt; 0.001). High/very high CVR was more frequent in SEC lower classes (P = 0.047). Conclusions Cardiovascular risk and socioeconomic status were simultaneously registered in 1.2% of the population. Highest Cardiovascular Risk is more frequent in lower SEC classes, males, older and residing in the southern region. Docotr's awareness on these themes mst be increased.


2017 ◽  
Vol 118 (9) ◽  
pp. 737-742 ◽  
Author(s):  
Bin Yu ◽  
Junwei Shao ◽  
Fei Yu ◽  
Qing Zhang ◽  
Li Liu ◽  
...  

AbstractPrevious studies have demonstrated adverse mental health effects of Pb exposure. The purpose of this study is to investigate the relationship between consumption of preserved egg (PE), a high-Pb-containing food and depressive symptoms among adults in China. A sample of 25 213 adults (mean age 41·4 (sd 11·8) years; males, 53·9 %) in Tianjin, China, was studied in a cross-sectional analysis. Dietary intake including PE was assessed using a valid self-administered FFQ. Depressive symptoms were assessed using the Self-Rating Depression Scale (SDS). The association was estimated by OR using logistic regression models adjusted for multiple confounders. The prevalence of elevated depressive symptoms was 6·6 % (SDS≥50). Compared with the least frequent PE consumption (<once/week), multivariable adjusted OR for elevated depressive symptoms were 1·52 (95 % CI 1·28, 1·81), 2·24 (95 % CI 1·76, 2·81) and 3·31 (95 % CI 2·52, 4·30) for consumption of once, 2–3 times and ≥4 times/week, respectively (Pfor trend<0·0001), indicating a clear dose–response relationship. The results suggested that higher consumption of PE was strongly associated with depressive symptoms among adults in China. These findings underscore the need to consider dietary Pb exposure as a risk factor for psychological distress.


1992 ◽  
Vol 22 (1) ◽  
pp. 159-172 ◽  
Author(s):  
R. Fuhrer ◽  
T. C. Antonucci ◽  
M. Gagnon ◽  
J.-F. Dartigues ◽  
P. Barberger-Gateau ◽  
...  

SYNOPSISAs part of a 5-year, prospective, epidemiological survey of normal and pathological ageing, this cross-sectional analysis examines the relationship between depressive symptomatology (CES-D) and cognitive functioning (MMS) in a community sample of 2792 non-institutionalized persons (age ≥ 65) living in Southwest France. Of the sample, 13·4%, report depressive symptoms above the cut-off. A significant association was found between CES-D and MMS scores, but after adjusting for age, living arrangements, and especially functional limitations, the relationship remained strong only for women.


2018 ◽  
Vol 36 (3) ◽  
pp. 323-328 ◽  
Author(s):  
Ansa Talvikki Rantanen ◽  
Jyrki Jaakko Antero Korkeila ◽  
Eliisa Susanna Löyttyniemi ◽  
Ulla Kirsti Maria Saxén ◽  
Päivi Elina Korhonen

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