scholarly journals Allelic Variation in Taste Genes Is Associated with Taste and Diet Preferences and Dental Caries

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1491 ◽  
Author(s):  
Linda Eriksson ◽  
Anders Esberg ◽  
Simon Haworth ◽  
Pernilla Lif Holgerson ◽  
Ingegerd Johansson
Keyword(s):  
Food Intake ◽  
Food Preference ◽  
Glucose Transporter ◽  
Allelic Variation ◽  
Food Selection ◽  
Taste Receptor ◽  
Food Preferences ◽  
Sweet Taste ◽  
Taste Perception ◽  
Diet Preferences

Taste and diet preferences are complex and influenced by both environmental and host traits while affecting both food selection and associated health outcomes. The present study genotyped 94 single nucleotide polymorphisms (SNPs) in previously reported taste and food intake related genes and assessed associations with taste threshold (TT) and preferred intensity (PT) of sweet, sour and bitter, food preferences, habitual diet intake, and caries status in healthy young Swedish men and women (n = 127). Polymorphisms in the GNAT3, SLC2A4, TAS1R1 and TAS1R2 genes were associated with variation in TT and PT for sweet taste as well as sweet food intake. Increasing PT for sweet was associated with increasing preference and intake of sugary foods. Similarly, increasing TT for sour was associated with increasing intake of sour foods, whereas the associations between food preference/intake and TT/PT for bitter was weak in this study group. Finally, allelic variation in the GNAT3, SLC2A2, SLC2A4, TAS1R1 and TAS1R2 genes was associated with caries status, whereas TT, PT and food preferences were not. It was concluded that variations in taste receptor, glucose transporter and gustducin encoding genes are related to taste perception, food preference and intake as well as the sugar-dependent caries disease.

Taste Perception and Cerebral Activity in the Human Gustatory Cortex Induced by Glucose, Fructose, and Sucrose Solutions

2019 ◽  
Vol 44 (7) ◽  
pp. 435-447 ◽  
Author(s):  
Thomas Mouillot ◽  
Sophie Barthet ◽  
Lucie Janin ◽  
Camille Creteau ◽  
Hervé Devilliers ◽  
...  
Keyword(s):  
Taste Receptor ◽  
Sweet Taste ◽  
Molar Concentration ◽  
Cortical Activation ◽  
Taste Perception ◽  
Gustatory Cortex ◽  
Intensity Perception ◽  
Sucrose Solutions ◽  
Significant Difference ◽  
Sweetness Intensity

Abstract Glucose, fructose, and sucrose are important carbohydrates in Western diets with particular sweetness intensity and metabolisms. No study has compared their cerebral detection and their taste perception. Gustatory evoked potentials (GEPs), taste detection thresholds, intensity perception, and pleasantness were compared in response to glucose, fructose, and sucrose solutions at similar sweetness intensities and at identical molar concentrations. Twenty-three healthy subjects were randomly stimulated with 3 solutions of similar sweetness intensity (0.75 M of glucose, 0.47 M of fructose and 0.29 M of sucrose – sit. A), and with an identical molar concentration (0.29 M – sit. B). GEPs were recorded at gustatory cortex areas. Intensity perception and hedonic values of each solution were evaluated as were gustatory thresholds of the solutions. No significant difference was observed concerning the GEP characteristics of the solutions according to their sweetness intensities (sit. A) or their molar concentration (sit. B). In sit. A, the 3 solutions were perceived to have similar intensities and induced similar hedonic sensations. In sit. B, the glucose solution was perceived to be less intense and pleasant than the fructose and the sucrose solutions (P < 0.001) and the fructose solution was perceived to be less intense and pleasant than the sucrose (P < 0.001). Since GEP recordings were similar for glucose, fructose, and sucrose solutions whatever the concentrations, activation of same taste receptor induces similar cortical activation, even when the solutions were perceived differently. Sweet taste perception seems to be encoded by a complex chemical cerebral neuronal network.

scholarly journals New Insights on the Evolution of the Sweet Taste Receptor of Primates Adapted to Harsh Environments

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2359
Author(s):  
Nur Aida Md Tamrin ◽  
Ramlah Zainudin ◽  
Yuzine Esa ◽  
Halimah Alias ◽  
Mohd Noor Mat Isa ◽  
...  
Keyword(s):  
Phylogenetic Trees ◽  
Environmental Changes ◽  
Receptor Gene ◽  
Taste Receptor ◽  
Sensory Information ◽  
Sweet Taste ◽  
Taste Perception ◽  
Sweet Taste Receptor ◽  
Dietary Preferences ◽  
Starting Point

Taste perception is an essential function that provides valuable dietary and sensory information, which is crucial for the survival of animals. Studies into the evolution of the sweet taste receptor gene (TAS1R2) are scarce, especially for Bornean endemic primates such as Nasalis larvatus (proboscis monkey), Pongo pygmaeus (Bornean orangutan), and Hylobates muelleri (Muller’s Bornean gibbon). Primates are the perfect taxa to study as they are diverse dietary feeders, comprising specialist folivores, frugivores, gummivores, herbivores, and omnivores. We constructed phylogenetic trees of the TAS1R2 gene for 20 species of anthropoid primates using four different methods (neighbor-joining, maximum parsimony, maximum-likelihood, and Bayesian) and also established the time divergence of the phylogeny. The phylogeny successfully separated the primates into their taxonomic groups as well as by their dietary preferences. Of note, the reviewed time of divergence estimation for the primate speciation pattern in this study was more recent than the previously published estimates. It is believed that this difference may be due to environmental changes, such as food scarcity and climate change, during the late Miocene epoch, which forced primates to change their dietary preferences. These findings provide a starting point for further investigation.

Sweet taste receptor gene TAS1R3 polymorphisms related to food preferences, biochemical parameters and body composition

Nutrition ◽  
2018 ◽  
Vol 50 ◽  
pp. e4
Author(s):  
S. Perna ◽  
M. Nichetti ◽  
F. Moncaglieri ◽  
I. Avanzato ◽  
D. Spadaccini ◽  
...  
Keyword(s):  
Body Composition ◽  
Biochemical Parameters ◽  
Receptor Gene ◽  
Taste Receptor ◽  
Food Preferences ◽  
Sweet Taste ◽  
Sweet Taste Receptor

scholarly journals Taste Perception in School Children: Is There an Association with Dental Caries?

2020 ◽  
Vol 24 (2) ◽  
pp. 102-106
Author(s):  
Edibe Egil ◽  
Ali Menteş
Keyword(s):  
Oral Health ◽  
Dental Caries ◽  
School Children ◽  
Health Knowledge ◽  
Food Selection ◽  
Sweet Taste ◽  
Taste Perception ◽  
Caries Experience ◽  
Occlusal Caries ◽  
Approximal Caries

SummaryBackground/Aim: Individuals make food choices based on a number of physiological, nutritional, environmental and socioeconomic factors but sensory qualities of food namely the taste has priority as the determinant in food selection. The purpose of the study is to evaluate sweet, salty, sour and bitter taste perceptions of school children and compare them in term of caries experience.Material and Methods: Two hundred children aged from 6-13 were included in the study. The dental examinations of children were performed using DMF(T), DMF(S), df(t) and df(s) indices. Questionnaires were presented to parents to record the socioeconomic and educational levels, oral health knowledge, child’s general health, oral health habits and fluoride exposure. Children rinsed sucrose (12g/L; 24g/L), sodium chloride (2g/L; 4g/L), citric acid (0,6g/L; 1,20g/L) and caffeine (0,27g/L; 0,54g/L) solutions randomly and the taste perception was recorded. Relationship between the taste perception and caries experience were evaluated.Results: A significant correlation was found between 2 g/L of NaCl and age (p= 0,007, r= 0,178). When occlusal or approximal caries of the children aged from 6 to 9 were discriminated, the Spearman’s test found a weak positive correlation between occlusal caries and higher sweet taste (24 g/L sucrose) (r= 0,232; p= 0,021) and a weak negative correlation between approximal caries and higher salty taste (4 g/L NaCl) (r= –0,225; p= 0,025).Conclusions: Age should be considered in the assessment of taste perception of children. Additionally, there is a weak relationship between taste perceptions and dental caries. These data suggest that further studies need to focus on the effect of taste preferences on dental caries.

scholarly journals Exploring Associations between Interindividual Differences in Taste Perception, Oral Microbiota Composition, and Reported Food Intake

Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1167 ◽  
Author(s):  
Camilla Cattaneo ◽  
Patrizia Riso ◽  
Monica Laureati ◽  
Giorgio Gargari ◽  
Ella Pagliarini
Keyword(s):  
Food Intake ◽  
Eating Habits ◽  
Saturated Fat ◽  
Sweet Taste ◽  
Oral Microbiome ◽  
Taste Perception ◽  
Oral Microbiota ◽  
Microbiota Composition

The role of taste perception, its relationship with oral microbiota composition, and their putative link with eating habits and food intake were the focus of the present study. A sample of 59 reportedly healthy adults (27 male, 32 female; age: 23.3 ± 2.6 years) were recruited for the study and taste thresholds for basic tastes, food intake, and oral microbiota composition were evaluated. Differences in taste perception were associated with different habitual food consumption (i.e., frequency) and actual intake. Subjects who were orally hyposensitive to salty taste reported consuming more bakery and salty baked products, saturated-fat-rich products, and soft drinks than hypersensitive subjects. Subjects hyposensitive to sweet taste reported consuming more frequently sweets and desserts than the hypersensitive group. Moreover, subjects hypersensitive to bitter taste showed higher total energy and carbohydrate intakes compared to those who perceived the solution as less bitter. Some bacterial taxa on tongue dorsum were associated with gustatory functions and with vegetable-rich (e.g., Prevotella) or protein/fat-rich diets (e.g., Clostridia). Future studies will be pivotal to confirm the hypothesis and the potential exploitation of oral microbiome as biomarker of long-term consumption of healthy or unhealthy diets.

Effect of amino acid imbalance on food intake and preference

1962 ◽  
Vol 202 (1) ◽  
pp. 165-170 ◽  
Author(s):  
Juan C. Sanahuja ◽  
Alfred E. Harper
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Food Preference ◽  
Food Selection ◽  
Amino Acid Mixture ◽  
Acid Mixture ◽  
Balanced Diet ◽  
Amino Acid Imbalance ◽  
Ad Libitum ◽  
Protein Free Diet

Effects of an amino acid imbalance, caused by adding 3.8% of an amino acid mixture lacking histidine to a diet containing 6% of beef fibrin, on the food intake and food preference of protein-depleted rats are described. After being depleted, animals fed the balanced or imbalanced diets ate equal amounts for 3 days, then both growth rate and food intake of those fed the imbalanced diet dropped. When protein-depleted rats were fed the balanced or imbalanced diet together with a protein-free diet, neither group ate the protein-free diet during the first 3 days. Thereafter, animals fed the imbalanced diet began to eat the protein-free diet in preference to the imbalanced diet, even though the latter would support growth and the former would not. Animals fed ad libitum the balanced diet or the imbalanced diet plus histidine did not eat the protein-free diet at all. These observations indicate that both food intake and food selection are influenced by the amino acid pattern of the diet.

scholarly journals Sweet and Umami Taste Perception Differs with Habitual Exercise in Males

Nutrients ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 155 ◽  
Author(s):  
Emma Feeney ◽  
Laura Leacy ◽  
Mark O’Kelly ◽  
Niamh Leacy ◽  
Abbie Phelan ◽  
...  
Keyword(s):  
Food Intake ◽  
Eating Behaviour ◽  
Sweet Taste ◽  
Taste Perception ◽  
Taste Intensity ◽  
High Concentration ◽  
Umami Taste ◽  
Perceived Intensity ◽  
Low Concentrations ◽  
Habitual Exercise

Taste is influenced by several factors. However, whether habitual exercise level is associated with differences in taste perception has received little investigation. The aim of this study was to determine if habitual exercise is associated with differences in taste perception in men. Active (n = 16) and inactive (n = 14) males, between ages 18–55, underwent two days of sensory testing, using prototypical taste stimuli of high and low concentrations for sweet, salt, bitter, sour, umami, and carbohydrate (maltodextrin). Mean perceived intensity and hedonic ratings were recorded. Eating behaviour was assessed by the three factor eating questionnaire and food intake by EPIC food frequency questionnaire (FFQ). There were moderate to large differences between the two groups in perceived intensity for sweet taste at the high concentration and umami taste at both high and low concentrations, with active males recording a higher perceived intensity (p < 0.05 for all). The active group also recorded a greater dislike for umami low and carbohydrate low concentration (p < 0.01). Salt, bitter and sour perception did not significantly differ between the two groups. FFQ analysis showed no difference in % energy from macronutrients between the groups. Eating behaviour traits correlated with sweet taste intensity and umami taste liking, independent of activity status. Results indicated that sweet and umami taste perception differ in active compared to inactive males. Habitual exercise level should be considered in taste perception research and in product development. Whether differences in taste perception could be one factor influencing food intake and thus energy balance with habitual exercise warrants further investigation.

scholarly journals Genetic variation in taste perception: does it have a role in healthy eating?

2010 ◽  
Vol 70 (1) ◽  
pp. 135-143 ◽  
Author(s):  
E. Feeney ◽  
S. O'Brien ◽  
A. Scannell ◽  
A. Markey ◽  
E. R. Gibney
Keyword(s):  
Healthy Eating ◽  
Taste Receptor ◽  
Food Preferences ◽  
Holistic Approach ◽  
Taste Perception ◽  
Salty Taste ◽  
Brassica Vegetables ◽  
Differential Perception ◽  
Genetic And Environmental Factors ◽  
And Gender

Taste is often cited as the factor of greatest significance in food choice, and has been described as the body's ‘nutritional gatekeeper’. Variation in taste receptor genes can give rise to differential perception of sweet, umami and bitter tastes, whereas less is known about the genetics of sour and salty taste. Over twenty-five bitter taste receptor genes exist, of which TAS2R38 is one of the most studied. This gene is broadly tuned to the perception of the bitter-tasting thiourea compounds, which are found in brassica vegetables and other foods with purported health benefits, such as green tea and soya. Variations in this gene contribute to three thiourea taster groups of people: supertasters, medium tasters and nontasters. Differences in taster status have been linked to body weight, alcoholism, preferences for sugar and fat levels in food and fruit and vegetable preferences. However, genetic predispositions to food preferences may be outweighed by environmental influences, and few studies have examined both. The Tastebuddies study aimed at taking a holistic approach, examining both genetic and environmental factors in children and adults. Taster status, age and gender were the most significant influences in food preferences, whereas genotype was less important. Taster perception was associated with BMI in women; nontasters had a higher mean BMI than medium tasters or supertasters. Nutrient intakes were influenced by both phenotype and genotype for the whole group, and in women, the AVI variation of the TAS2R38 gene was associated with a nutrient intake pattern indicative of healthy eating.

scholarly journals Association between Salivary Leptin Levels and Taste Perception in Children

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Lénia Rodrigues ◽  
Rosa Espanca ◽  
Ana Rodrigues Costa ◽  
Célia Miguel Antunes ◽  
Clarinda Pomar ◽  
...  
Keyword(s):  
Bitter Taste ◽  
Taste Receptor ◽  
Sweet Taste ◽  
Normal Weight ◽  
Taste Perception ◽  
Taste Sensitivity ◽  
Threshold Detection ◽  
Leptin Receptors ◽  
Whole Saliva

The satiety inducing hormone leptin acts not only at central nervous system but also at peripheral level. Leptin receptors are found in several sense related organs, including the mouth. A role of leptin in sweet taste response has been suggested but, until now, studies have been based on in vitro experiments, or in assessing the levels of the hormone in circulation. The present study investigated whether the levels of leptin in saliva are related to taste perception in children and whether Body Mass Index (BMI) affects such relationship. Sweet and bitter taste sensitivity was assessed for 121 children aged 9-10 years and unstimulated whole saliva was collected for leptin quantification, using ELISA technique. Children females with lower sweet taste sensitivity presented higher salivary leptin levels, but this is only in the normal weight ones. For bitter taste, association between salivary leptin and caffeine threshold detection was observed only in preobese boys, with higher levels of salivary hormone in low sensitive individuals. This study is the first presenting evidences of a relationship between salivary leptin levels and taste perception, which is sex and BMI dependent. The mode of action of salivary leptin at taste receptor level should be elucidated in future studies.

scholarly journals Food Preferences in Dogs: Effect of Dietary Composition and Intrinsic Variables on Diet Selection

Animals ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 219 ◽  
Author(s):  
Raúl A. Alegría-Morán ◽  
Sergio A. Guzmán-Pino ◽  
Juan Ignacio Egaña ◽  
Carem Muñoz ◽  
Jaime Figueroa
Keyword(s):  
Dry Matter ◽  
Food Preference ◽  
Negative Impact ◽  
Food Selection ◽  
Food Preferences ◽  
Principal Component ◽  
Food Choices ◽  
Food Cues ◽  
Hot Season ◽  
Fourth Component

A ten-year food preference database (2007–2017) was used to relate food selection in dogs to the nutritional components of diets by doing a principal component analysis (PCA) and a linear regression between components obtained and dogs’ preferences. Intake and preference of preferred diets were analyzed by dogs’ sex, breed, age, body weight, and the season of the year (hot or cold). The fourth component after PCA presented a relation with food preferences (OR = −2.699, p = 0.026), showing negative correlations with crude fiber (rho = −0.196; P = 0.038) and dry matter (rho = −0.184; p = 0.049). Weight (OR = −1.35; p < 0.001), breed, both Boxer (OR = 10.62; p = 0.003) and Labrador Retriever (OR = 26.30; p < 0.001), and season (hot season) (OR = −5.27; p < 0.001) all influenced animals’ intake. Boxers presented a lower food preference compared to the other breeds (OR = −44.3; p < 0.001), while animals’ weight influenced preferences only in Boxers (OR = 2.02; p < 0.001). Finally, age and sex did not affect dogs’ preference or intake of preferred diets. Thus dry matter and fiber content have a negative impact on dogs’ food choices. Dogs’ weight, breed, and season affected food intake, but only breed affected dogs’ preferences, which is probably explained by adaptive changes in the detection, metabolization, and learning of nutritive food cues.

Sign in / Sign up

Export Citation Format

Share Document