scholarly journals Analysis of the Association between Fat Mass Distribution and Bone Mass in Chinese Male Adolescents at Different Stages of Puberty

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2163
Author(s):  
Kai-Li Deng ◽  
Hui Li ◽  
Wan-Yu Yang ◽  
Jin-Li Hou ◽  
Yang Xu ◽  
...  
Keyword(s):  
Bone Mass ◽  
Fat Mass ◽  
Broadband Ultrasound Attenuation ◽  
Fat Distribution ◽  
Stiffness Index ◽  
Male Adolescents ◽  
Bone Parameters ◽  
Prepubertal Boys ◽  
Pubertal Boys ◽  
Chinese Male

Background: Bone mineral acquisition during adolescence is crucial for maximizing peak bone mass. Fat mass (FM) and bone mass are closely related. This study investigated the association of FM distribution with bone mass in Chinese male adolescents. Method: A total of 693 male adolescents aged 10–18 years were recruited from a secondary school in Jiangmen, China. Their bone mass and body composition were measured by quantitative ultrasound and bioelectrical impedance analysis, respectively. The associations of the measures of fat distribution with bone parameters, i.e., broadband ultrasound attenuation, speed of sound (SOS), and stiffness index (SI), were analyzed using multiple linear regression. Age, height, body mass index, stage of puberty, physical activity, sedentary behavior, dietary energy intake, and dietary calcium and vitamin D intake were adjusted in the model. Further subgroup analyses of prepubertal and pubertal participants were conducted. Results: The measures of fat distribution showed negative associations with SOS and SI in total subjects (p < 0.010). In prepubertal boys, the measures of fat distribution were only associated with SOS (β = −0.377 to −0.393, p < 0.050). In pubertal boys, the measures of fat distribution had associations with all bone parameters (β = −0.205 to −0.584, p < 0.050). The strongest association was between trunk FM and SOS (β = −0.584, p < 0.001). Conclusion: This study supported that the measures of fat distribution were negatively associated with bone parameters in Chinese male adolescents. Trunk FM had the strongest association with bone parameter. These associations appear to be stronger in pubertal boys than in prepubertal boys.

Superiority of skinfold measurements and waist over waist-to-hip ratio for determination of body fat distribution in a population-based cohort of Caucasian Dutch adults

2007 ◽  
Vol 156 (6) ◽  
pp. 655-661 ◽  
Author(s):  
Iris J G Ketel ◽  
Mariken N M Volman ◽  
Jacob C Seidell ◽  
Coen D A Stehouwer ◽  
Jos W Twisk ◽  
...  
Keyword(s):  
Body Fat ◽  
Fat Mass ◽  
Fat Distribution ◽  
Skinfold Thickness ◽  
Population Based ◽  
Anthropometric Measurement ◽  
Hip Circumference ◽  
Waist To Hip Ratio ◽  
Skinfold Measurements

Objective: To determine which anthropometric measurement is the most reliable alternative for fat distribution as measured by dual-energy X-ray absorptiometry (DXA). Design: Population-based survey carried out in Amsterdam, The Netherlands. Subjects and methods: A total of 376 individuals (200 women) with a mean age of 36.5 years and mean body mass index (BMI) of 24.0 (±3.1) kg/m2 underwent various anthropometric and DXA measurements of central (CFM) and peripheral fat mass (PFM). Furthermore, for the assessment of apple-shaped body composition, CFM-to-PFM ratio was calculated. Anthropometric measurements were waist and hip circumference, waist-to-hip ratio (WHR), BMI, waist/length and the skinfold thickness of biceps, triceps, suprailiacal (SI), subscapular (SS) and upper leg. We determined whether equations of combined anthropometrics were even more reliable for the assessment of fat mass. Results: In both women and men, reliable alternatives for CFM are central skinfolds and waist (Pearson’s correlation (r) ≥ 0.8). Peripheral skinfolds are the best predictors of PFM (r ≥ 0.8). In contrast, WHR correlated only marginally with any of the DXA measurements. Equations based on several anthropometric variables correlate with CFM even better (R2 ≥ 0.8). CFM-to-PFM ratio has the highest correlation with the ratio (SS+SI)/BMI in women (r = 0.66) and waist/length in men (r = 0.71). Equations are reasonable alternatives of CFM-to-PFM ratio (R2 ≥ 0.5). Conclusion: Waist and skinfolds are reliable alternatives for the measurement of body fat mass in a cohort of Caucasian adults. WHR is not appropriate for the measurement of fat distribution.

Increased fat mass may be protective of bone mass in young male cancer survivors

Bone ◽  
2010 ◽  
Vol 47 ◽  
pp. S189-S190
Author(s):  
J.S. Walsh ◽  
R. Eastell ◽  
R.E. Coleman ◽  
J.A. Snowden ◽  
S.M. Shalet ◽  
...  
Keyword(s):  
Bone Mass ◽  
Cancer Survivors ◽  
Fat Mass ◽  
Young Male

scholarly journals Testosterone therapy decreases subcutaneous fat and adiponectin in aging men

2012 ◽  
Vol 166 (3) ◽  
pp. 469-476 ◽  
Author(s):  
L Frederiksen ◽  
K Højlund ◽  
D M Hougaard ◽  
T H Mosbech ◽  
R Larsen ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fat Mass ◽  
Subcutaneous Fat ◽  
Fat Distribution ◽  
Controlled Study ◽  
Testosterone Therapy ◽  
Testosterone Levels ◽  
Bioavailable Testosterone ◽  
Aging Men ◽  
Total Fat

ObjectiveTestosterone therapy increases lean body mass and decreases total fat mass in aging men with low normal testosterone levels. The major challenge is, however, to determine whether the metabolic consequences of testosterone therapy are overall positive. We have previously reported that 6-month testosterone therapy did not improve insulin sensitivity. We investigated the effect of testosterone therapy on regional body fat distribution and on the levels of the insulin-sensitizing adipokine, adiponectin, in aging men with low normal bioavailable testosterone levels.DesignA randomized, double-blinded, placebo-controlled study on 6-month testosterone treatment (gel) in 38 men, aged 60–78 years, with bioavailable testosterone <7.3 nmol/l, and a waist circumference >94 cm.MethodsCentral fat mass (CFM) and lower extremity fat mass (LEFM) were measured by dual X-ray absorptiometry. Subcutaneous abdominal adipose tissue (SAT), visceral adipose tissue (VAT), and thigh subcutaneous fat area (TFA) were measured by magnetic resonance imaging. Adiponectin levels were measured using an in-house immunofluorometric assay. Coefficients (b) represent the placebo-controlled mean effect of intervention.ResultsLEFM was decreased (b=−0.47 kg, P=0.07) while CFM did not change significantly (b=−0.66 kg, P=0.10) during testosterone therapy. SAT (b=−3.0%, P=0.018) and TFA (b=−3.0%, P<0.001) decreased, while VAT (b=1.0%, P=0.54) remained unchanged. Adiponectin levels decreased during testosterone therapy (b=−1.3 mg/l, P=0.001).ConclusionTestosterone therapy decreased subcutaneous fat on the abdomen and lower extremities, but visceral fat was unchanged. Moreover, adiponectin levels were significantly decreased during testosterone therapy.

scholarly journals Acute fat loss does not affect bone mass

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marie K. Lagerquist ◽  
Karin L. Gustafsson ◽  
Petra Henning ◽  
Helen Farman ◽  
Jianyao Wu ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Bone Mass ◽  
Fat Mass ◽  
Tissue Loss ◽  
Obese Mice ◽  
Long Term Effects ◽  
High Bone Mass ◽  
Age Related ◽  
Total Fat ◽  
Old Mice

AbstractObesity has previously been thought to protect bone since high body weight and body mass index are associated with high bone mass. However, some more recent studies suggest that increased adiposity negatively impacts bone mass. Here, we aimed to test whether acute loss of adipose tissue, via adipocyte apoptosis, alters bone mass in age-related obese mice. Adipocyte apoptosis was induced in obese male FAT-ATTAC mice through AP20187 dimerizer-mediated activation of caspase 8 selectively in adipocytes. In a short-term experiment, dimerizer was administered to 5.5 month-old mice that were terminated 2 weeks later. At termination, the total fat mass weighed 58% less in dimerizer-treated mice compared with vehicle-treated controls, but bone mass did not differ. To allow for the detection of long-term effects, we used 9-month-old mice that were terminated six weeks after dimerizer administration. In this experiment, the total fat mass weighed less (− 68%) in the dimerizer-treated mice than in the controls, yet neither bone mass nor biomechanical properties differed between groups. Our findings show that adipose tissue loss, despite the reduced mechanical loading, does not affect bone in age-related obese mice. Future studies are needed to test whether adipose tissue loss is beneficial during more severe obesity.

scholarly journals Liver Fat Content and Body Fat Distribution in Youths with Excess Adiposity

2018 ◽  
Vol 7 (12) ◽  
pp. 528 ◽  
Author(s):  
Robinson Ramírez-Vélez ◽  
Mikel Izquierdo ◽  
Jorge Correa-Bautista ◽  
María Correa-Rodríguez ◽  
Jacqueline Schmidt-RioValle ◽  
...  
Keyword(s):  
Body Fat ◽  
Fat Mass ◽  
Fat Distribution ◽  
Fat Content ◽  
Body Fat Distribution ◽  
Healthy Diet ◽  
Liver Fat ◽  
Liver Fat Content ◽  
Excess Adiposity ◽  
Distribution Parameters

This study had two main objectives: To examine the association between body fat distribution and non-alcoholic fatty liver disease (NAFLD) and liver fat content, and to determine whether the relationship between NAFLD and regional body fat distribution, with respect to liver fat content in youths with excess adiposity, is independent of cardiorespiratory fitness (CRF) and a healthy diet. Liver fat content (controlled attenuation parameter (CAP)), body fat distribution (body mass index (BMI) z-score, waist circumference, waist-to-height ratio, fat mass/height, body fat percentage, total fat mass, android-to-gynoid fat mass ratio, visceral adipose tissue (VAT), and lean mass index, determined by dual-energy X-ray absorptiometry (DXA)), CRF (20-m shuttle-run test), and healthy diet (adherence to the Mediterranean diet by KIDMED questionnaire) were measured in 126 adolescents (66% girls) aged between 11 and 17 years. Participants were assigned to two groups according to the presence or absence of hepatic steatosis (CAP values ≥225 dB/m or <225 dB/m of liver fat, respectively). Considering the similar total fat values for the two groups (>30% by DXA), youths with NAFLD had higher fat distribution parameters than those without NAFLD, regardless of sex, age, puberty stage, lean mass index, CRF, and healthy diet (p < 0.01). In the non-NAFLD group, the association between hepatic fat and fat distribution parameters presented a similar pattern, although the association was statistically insignificant after adjusting for a potential confounding variable (ps > 0.05), except for the case of VAT. Body fat distribution parameters were higher in youths with NAFLD compared to those without NAFLD. Additionally, body fat distribution showed a significant association with liver fat content as assessed by CAP in youths with NAFLD independent of CRF and adherence to the Mediterranean diet, supporting the notion that upper body fat distribution might play a pivotal role in the development of NAFLD in adolescents. These results may have implications for the clinical management of youths with excess adiposity given the high prevalence of NAFLD in children and young adults.

scholarly journals Association between self-reported walking speed and calcaneal stiffness index in postmenopausal Japanese women

2020 ◽  
Author(s):  
Yoshihito Tomita ◽  
Kazuhiko Arima ◽  
Satoshi Mizukami ◽  
Ritsu Tsujimoto ◽  
Shin-ya Kawashiri ◽  
...  
Keyword(s):  
Bone Mass ◽  
Grip Strength ◽  
Postmenopausal Women ◽  
Walking Speed ◽  
Linear Regression Analysis ◽  
Japanese Women ◽  
Community Dwelling ◽  
Stiffness Index ◽  
Public Health Issue ◽  
Increased Risk

Abstract Background; Osteoporosis and related fractures, a worldwide public health issue of growing concern, is characterized by compromised bone strength and an increased risk of fracture. Here we show an association between self-reported walking speed and bone mass among community-dwelling postmenopausal Japanese women aged 50 years and older.Design; Cross-sectional study.Setting and Participants; The survey population included 1008 postmenopausal women 50–92 years of age residing in rural communities.Methods; Self-reported walking speed was ascertained by asking the participants: “Is your walking speed faster than others of the same age and sex?” to which participants responded “yes (faster)” or “no (moderate/slower).” Calcaneal stiffness index was measured.Results; Women with a faster self-reported walking speed were younger and had a lower BMI, higher stiffness index, and higher grip strength than women with a slower walking speed. Multiple linear regression analysis adjusted for age, BMI, grip strength, comorbidity, current smoking, and alcohol drinking status showed a significant association between faster self-reported walking speed and higher calcaneal stiffness index (p < 0.001).Conclusions; Our findings suggest that questionnaires of walking speed may be useful for predicting bone mass and that a fast self-reported walking may benefit bone health in postmenopausal women.

scholarly journals Calcaneal Bone Quality and Physique in Elite Hungarian Male Athletes.

2020 ◽  
pp. 1-12
Keyword(s):  
Bone Quality ◽  
Weight Bearing ◽  
Broadband Ultrasound Attenuation ◽  
Male Athletes ◽  
Recreational Sport ◽  
Bone Status ◽  
Bone Parameters ◽  
Sport Activities ◽  
Calcaneal Quantitative Ultrasound ◽  
Type Of Exercise

Abstract Regular physical activity has favourable influence on the bone status. The purpose of this study was to analyze the relationships between the bone quality index (BQI) in the calcaneus and anthropometric variables in male elite athletes. Participants were Hungarian elite male athletes: kayak-canoe (KC, n=43); triathlon (T, n=16); track & field (TF, n=46); water-polo (WP, n=19). Their physique was characterised by Heath-Carter somatotype. Calcaneal Quantitative Ultrasound (QUS) parameters were registered by Sonost3000 densitometer. Differences in bone quality between the groups and correlation patterns between QUS and physique were analysed (p<0.05). There were significant differences in QUS parameters. T and TF had significantly higher SOS (speed of sound, m/s) values than WP. KC had lower SOS values than T athletes (TF: 1519.3±16.0; T: 1512.9±20.8; KC: 1505.6±12.4; W: 1495.1±10.8. BUA (broadband ultrasound attenuation, dB/MHz) was the largestest in TF but this only differed significantly from WP (TF: 106.5±14.8; T: 98.9±11.5; KC: 98.7±16.5; WP: 92.2±8.8). BQI (αSOS+βBUA) was higher in TF (92.0±16.7) than in KC (79.2±13.1), WP (69.3±10.0); it was higher in T (84.8±19.6) than WP. Muscle percentage correlated positively, while absolute bone measurements correlated inversely with bone parameters. Higher QUS values were associated with lower endomorphy and mesomorphy, while more linear physiques correlated with better bone parameters. Physique and type of exercise training appear to be associated with bone status. Both weight-bearing and non-weight bearing exercise improve calcaneus bone parameters such as BQI to different extents. It might be preferable to combine some weight-bearing exercise during the sessions, and it is also highly recommended after a competitive period and during recreational sport activities.

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