scholarly journals Copper and Copper/Zn Ratio in a Series of Children with Chronic Diseases: A Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3578
Author(s):  
Marlene Fabiola Escobedo-Monge ◽  
Enrique Barrado ◽  
Joaquín Parodi-Román ◽  
María Antonieta Escobedo-Monge ◽  
María Carmen Torres-Hinojal ◽  
...  
Keyword(s):  
Chronic Diseases ◽  
Atomic Absorption Spectrophotometry ◽  
Cross Sectional Study ◽  
Serum Copper ◽  
Normal Serum ◽  
Zn Deficiency ◽  
Cross Sectional ◽  
Inflammatory State ◽  
Copper Zinc ◽  
The Mean

Copper is an essential micronutrient for humans. A cross-sectional and comparative study was done to assess serum Cu levels and serum copper/zinc (Cu/Zn) ratio and its association with nutritional indicators in a series of children and adolescents with chronic diseases. Anthropometric, biochemical, dietary, body composition, and bone densitometry assessments were carried out. Serum Cu and Zn were measured by atomic absorption spectrophotometry. Seventy-eight patients (55% women) participated. The mean serum Cu in the entire series and by nutritional status through body mass index (BMI) was normal. Serum Cu decreased significantly with age and was meaningfully higher in children than in adolescents. The risk of finding altered Cu levels in children and men was higher than in adolescents and women, respectively. Twenty-two per cent of patients had abnormal serum copper levels, 13 had hypercupremia, and four had hypocupremia. The Cu/Zn ratio was greater than 1.00 for 87% of the patients, which is an indicator of an inflammatory state. All patients with hypozincemia and hypocupremia had deficient Zn intake, but only 65% of the patients with hypercupremia had dietary Zn deficiency. Consequently, the Cu/Zn ratio could indicate an inflammatory state and a high risk of zinc deficiency in this specific child population.

Estimation of Trace Elements in Gingival Crevicular Fluid and Serum-Comparative Study in Healthy and Periodontitis

2017 ◽  
Vol 9 (5) ◽  
Author(s):  
Bhagavathami Meenaksh ◽  
Chitraa R. Chandran ◽  
Aravindhan Thathchari Ranganathan ◽  
Kavindapadi Venkateswaran Rama ◽  
Valarmathy Srinivasan
Keyword(s):  
Trace Elements ◽  
Inductively Coupled Plasma ◽  
Gingival Crevicular Fluid ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Serum Copper ◽  
Cross Sectional ◽  
Inductively Coupled ◽  
Significant Difference ◽  
Copper Zinc

Background: This study aims to determine and compare the levels of trace elements copper, zinc, selenium and chromium in GCF and serum of patients with periodontitis and healthy individuals. Methods: This cross sectional study includes 24 study subjects recruited from the patients reporting to the Department of Periodontics , Tagore Dental College Chennai. All the selected patients were subjected to a clinical examination done by a single examiner. The estimation of trace elements Copper, Zinc, Selenium and Chromium in GCF and serum is performed using Perkin Elmer optima 5300 Inductively Coupled Plasma Emission Spectrometer (ICPOES). Results: GCF and serum copper levels showed no significant difference in both periodontitis and healthy groups . Selenium levels tend to be the same in both groups. Serum zinc levels are more in periodontitis patients than healthy subjects (p less than 0.01). GCF chromium levels are found to be more in patients with periodontitis than healthy. Conclusions : More research is therefore needed to monitor the role of these trace elements C with an increased sample size to ascertain whether they are associated with a reduced risk of periodontitis.

scholarly journals PERBEDAAN RERATA RASIO KALSIUM MAGNESIUM DAN RERATA RASIO NATRIUM KALIUM SERUM

2019 ◽  
Vol 1 (1) ◽  
pp. 22-29
Author(s):  
Joserizal Serudji ◽  
Helga Helga ◽  
Hafni Bachtiar
Keyword(s):  
District Hospital ◽  
Atomic Absorption Spectrophotometry ◽  
Cross Sectional Study ◽  
Maternal Serum ◽  
Severe Preeclampsia ◽  
Cross Sectional ◽  
Sodium Potassium ◽  
Smooth Muscle Function ◽  
Calcium Magnesium ◽  
The Mean

The high incidence of preeclampsia and eclampsia causes the importance of early detection especially eclampsia which is the main cause of maternal morbidity and mortality and bad perinatal outcome. The etiology was unknown, but is related to changes in electrolyte status. Electrolytes such as calcium (Ca2+), Magnesium (Mg2+), sodium (Na+) and potassium (K+) play an important role in pre-eclampsia and eclampsia because they contribute significantly in vascular smooth muscle function. This study was done to analyze the differences in mean levels of calcium magnesium ratio and sodium potassium ratio of maternal serum in severe preeclampsia and eclampsia. We performed an observasional comparative with cross sectional study on 16 women with severe preeclampsia and 16 women with eclampsia who met the inclusion criteria and there were no exclusion criteria. The samples were recruited in Dr. M Djamil general hospital Padang, Solok District Hospital, and Pariaman District Hospital from May 2015 to January 2016. The levels of calcium serum were examined by atomic absorption spectrophotometry (AAS), magnesium levels were examined by enzymatic metode, sodium and potassium levels were examined by ion selection electrode (ISE). The differences in mean levels of calcium magnesium ratio and sodium potassium ratio between the two groups was analyzed by using independent t test. The mean levels of calcium magnesium ratio in severe preeclampsia was significantly higher than eclampsia. The mean levels of sodium potassium ratio in severe preeclampsia was significantly lower than eclampsia.Keywords: Calcium magnesium ratio, sodium potassium ratio, severe preeclampsia, eclampsia

Assessment of Serum Copper State after Gastrectomy with Roux-en-Y Reconstruction for Gastric Cancer

2015 ◽  
Vol 32 (4) ◽  
pp. 301-305 ◽  
Author(s):  
Masatoshi Nakagawa ◽  
Kazuyuki Kojima ◽  
Mikito Inokuchi ◽  
Keiji Kato ◽  
Hirofumi Sugita ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cross Sectional Study ◽  
Physical Symptoms ◽  
Serum Copper ◽  
Curative Gastrectomy ◽  
Cross Sectional ◽  
Significant Difference ◽  
Male Patients ◽  
The Mean ◽  
Copper State

Background: Some recent reports have noted that copper deficiency can occur in obese patients who have undergone bariatric surgery, such as Roux-en-Y (RY) gastric bypass or biliopancreatic diversion, or in patients who receive enteral nutrition through a jejunostomy. No reports appear to have assessed the serum copper state of patients following gastrectomy with RY reconstruction for gastric cancer. Methods: A cross-sectional study was conducted from June 2013 to December 2014. Serum copper levels (SCLs) in 242 out-clinic patients who underwent curative gastrectomy were obtained. Patients were classified into an RY group (n = 208) and a non-RY group (n = 34). Results: Hypocupremia was identified in 3 patients in the RY group (1.4%), and 2 patients in the non-RY group (5.9%; p = 0.146), but none experienced any symptoms caused by hypocupremia. No significant difference in the mean SCL was seen between the RY group (105.8 ± 21.2 µg/dl) and non-RY group (107.9 ± 22.7 µg/dl; p = 0.499). In the RY group, the mean SCL was significantly lower in younger patients, patients with follow-up period <3 years, and male patients. Conclusion: Some patients developed hypocupremia after gastrectomy with RY reconstruction, but the number is acceptably low, and physical symptoms were unusual.

scholarly journals Profile of lifestyle of older elderly persons

2016 ◽  
Vol 19 (5) ◽  
pp. 819-826 ◽  
Author(s):  
Marilza Amaral Henrique de Souza ◽  
Elias Ferreira Porto ◽  
Eduardo Luiz de Souza ◽  
Kathleen Ingrid da Silva
Keyword(s):  
Chronic Diseases ◽  
Older Persons ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Elderly Persons ◽  
Cross Sectional ◽  
Lifestyle Questionnaire ◽  
Former Smokers ◽  
The Mean ◽  
Nutrition Component

Abstract Introduction: Lifestyle has been widely studied in recent years, especially in the context of longevity and aging well. Objective: The aim of this study was to analyze the lifestyle profile of older elderly persons and the relationship between lifestyle and chronic diseases. Method: A cross-sectional study evaluating 132 older persons aged over 74.6 years, who were resident of the Capão Redondo district of São Paulo, was carried out. The study was conducted in 23 institutions such as churches, community centers, parks, nursing homes and residences. All participants completed two questionnaires, with the first based on lifestyle and the second on socio-economic classification, and also answered some questions about the presence and control of non-communicable chronic diseases (NCDs). Result: the mean age was 78.8(±4.5) years and the respondents had a mean BMI of 25.5(±5.5). Most were women from social classes C and D. A total of 46 were former smokers, seven were smokers, and 82 had NCDs, with heart diseases the most prevalent. The mean lifestyle questionnaire score was 30.2(±3.5). There was no statistical difference in scores between those with NCDs and those that did not suffer from such diseases. The physical activity component had the lowest score, followed by the nutrition component. The prevalence of NCDs was significantly higher for smokers and former smokers than for those who had never smoked. Conclusion: The majority of older persons demonstrated an excellent lifestyle with healthy habits. Even those with a diagnosed NCD had a good lifestyle. Cardiovascular diseases were the most prevalent in this population. The risk of NCD was greater for smokers and former smokers than for those who had never smoked.

Estimation of Serum Copper and Zinc Levels among Tuberculosis Patients in Khartoum State

2020 ◽  
pp. 1-5
Author(s):  
Abdalla Eltoum Ali
Keyword(s):  
Absorption Spectrometry ◽  
Cross Sectional Study ◽  
Serum Copper ◽  
Control Group ◽  
P Value ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Copper And Zinc ◽  
The Mean ◽  
Zinc Levels

Background: Trace elements play an important role in tuberculosis infection because their deficiencies can be associated with impaired immunity. The aim to assessment the serum copper and zinc levels among the tuberculosis patients in Khartoum state Material: This is cross sectional study was conducted in Aboanja hospital in Khartoum state during the period from November 2016_January 2017.Citrated samples were collected from 100 study group , 50 tuberculosis patients , and 50 apparently healthy Individuals, Serum level of Zinc and Copper was measured by atomic absorption spectrometry. Result: The result is the mean level of Zinc in tuberculosis patients were significant decreased when compared with control group (P. value= <0.001) and also the mean level of Copper in tuberculosis patients significant increase when compared with group ( P. value = <0.001). Conclusion: This study showed significant decrease in level of Zinc and increase in level of Copper once compared with control group among tuberculosis patients. Keywords: Copper, Impaired immunity, Trace element, Tuberculosis, Zinc

scholarly journals Serum Zinc, Copper and Calcium Levels In Female Rheumatoid Arthritic Patients

2012 ◽  
Vol 7 (1) ◽  
pp. 18-22
Author(s):  
Arifa Alam Jelly ◽  
Shelina Begum ◽  
Sultana Ferdousi
Keyword(s):  
Rheumatoid Arthritis ◽  
Colorimetric Method ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Serum Copper ◽  
Copper Level ◽  
Cross Sectional ◽  
Healthy Female ◽  
Copper Zinc ◽  
Medical University

Background: Rheumatoid Arthritis is a chronic multi-system autoimmune inflammatory disease,  characterized by inflammatory synovitis involving symmetrical peripheral joints. Serum copper, zinc  and calcium levels are altered in Rheumatoid Arthritis.Objective: To observe serum zinc, copper and  calcium levels in patients with Rheumatoid Arthritis (RA).Methods: This cross sectional study was  conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University  (BSMMU), Shahbag, Dhaka from January to December 2010. For this, 60 female patients with  Rheumatoid arthritis aged 30-50 years were included in the study group. The patients were selected  from outpatient Department of Rheumatology wing of medicine in Bangabandhu Sheik Mujib Medical  University (BSMMU). For comparison age and BMI matched 30 apparently healthy female were also  studied. Serum calcium level was measured by Colorimetric method. Serum zinc and copper was  measured by Spectrophotometric method. For statistical analysis, independent sample t test was  performed by using SPSS for windows version-12.Results: In this study, serum zinc and calcium  levels were significantly lower (p<0.001) and serum copper level was significantly higher (p<0.001) in  the RA patients than those of control.Conclusion: This study may conclude that hypozincemia and  hypocalcemia and hypercupremia occur in RA. Therefore early detection of these micronutrient  abnormalities may be helpful for the physicians to prevent various complications in RA patients. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11155 J Bangladesh Soc Physiol. 2012, June; 7(1): 18-22

scholarly journals The Assessment of Spirituality Between Cancer and Chronic Inpatients: A Cross-Sectional Study

2021 ◽  
Author(s):  
YALAN LIU ◽  
HAO XUE ◽  
LI YAN ◽  
YULIN XIA ◽  
YILIN WANG
Keyword(s):  
Chronic Diseases ◽  
Demographic Data ◽  
Well Being ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Chronic Illness Therapy ◽  
Spiritual Well Being ◽  
Medium Level ◽  
The Mean

Abstract PurposeSpiritual well-being had protective effect on quality of life in cancer, due to the cultural, regional and custom differences,it was rarely been discussed between cancer and chronic diseases in Chongqing,China. We aimed at comparing the level of spirituality in two groups, and discussing its factors of subjects with cancer at county regions.MethodsA cross-sectional questionnaire survey was distributed to 630 inpatients who received treatment between January and December 2020 in Chongqing University Three Gorges Hospital.In addition to basic demographic data,spirituality was measured using the Chinese version of Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being (FACIT-Sp-12). The mean,standard deviation,independent t-tests, ANOVA and multiple regression were used for statistical description and analysis.ResultsSignificant differences were found between cancer and chronic diseases in total scores of FACIT-Sp-12 and each domain(P<0.05).The meaning, peace, faith and total scores in cancer were 11.21±3.38,10.66±4.46,11.43±3.54,and 33.3±10.35,respectively.Which were lower than chronic diseases (13.00±3.21,12.95±4.76,12.66±3.64,38.61±10.88,respectively). The spiritual well-being had significant differences in gender,character,and emotional with spouse for cancer (P<0.05).The male and extravert character were significantly associated with a greater spiritual well-being.ConclusionThe study shows a medium level of spiritual well-being in cancer, which stands the population with lower economic and education in county regions. It suggests that under the current nursing mode, we should provide specifically spiritual care to the female,introvert and those with poor relationship with spouses, and create a harmonious doctor-patient environment to improve the spiritual well-being.Retrospectively registeredJSCC-D-21-01528,17 Sep 2021

scholarly journals The Association between The Degree of Liver Cirrhosis Severity and Zinc Serum Level

2020 ◽  
Vol 1 (1) ◽  
pp. 5
Author(s):  
Budi Yuwono ◽  
Ummi Maimunah ◽  
Budi Widodo
Keyword(s):  
Liver Cirrhosis ◽  
Serum Level ◽  
Serum Levels ◽  
Atomic Absorption Spectrophotometry ◽  
Statistical Test ◽  
Zn Deficiency ◽  
Impaired Liver Function ◽  
Cross Sectional ◽  
The Mean ◽  
Ctp Score

Background: Impaired liver function in LC (Liver Cirrhosis) can cause Zinc deficiency (Zn). One of the causes of Zn deficiency in LC is decreased albumin synthesis, whereas albumin is required as the main Zn binding protein in plasma. However, some studies of the severity of LC with Zn serum levels still provide controversial results.Objective: To determine the association between the degree of LC severity and Zn serum level.Methods: The subjects of this study were LC patients in Gastroentero-Hepatology Unit and Internal medicine wards in of Dr. Soetomo General Hospital Surabaya for three months. Diagnosis of LC was based on clinical examination according to Soehardjno-Soebandiri criteria and other findings (ultrasound or endoscopy). The degree of LC severity was determined based on the CTP score (Child-Turcotte-Pugh). Serum Zn concentration was measured by atomic absorption spectrophotometry method. The research design used the cross-sectional method. The statistical test used was Spearman correlation.Results: Forty-three patients fulfilled the study criteria. The subjects consisted of 27 males (62.8%) and 16 females (37.2%) with the mean age of 53.81 ± 8.67 years. Based on the CTP scores, we obtained CTP A of 4 patients (9.3%), CTP B of 19 patients (44.2%) and CTP C of 20 patients (46.5%). The mean of Zn serum level in CTP A, CTP B, and CTP C score was 58.3 ± 19.6 μg/dl, 43.4 ± 14.5 μg/dl and 31.6 ± 10 μg/dl respectively. The result of the statistical test showed a significant correlation between LC severity and Zn serum level (p <0.05 and r = -0.583).Conclusion: The heavier the severity of LC, the lower Zn serum levels.

Brief Overview and Experience of Visual Evoked Potential of First 67 cases at Referral Neuroscience Hospital in Bangladesh

2020 ◽  
Vol 6 (2) ◽  
pp. 74-77
Author(s):  
Mohammad Enayet Hussain ◽  
Bithi Debnath ◽  
AFM Al Masum Khan ◽  
Md Ferdous Mian ◽  
Md Nahidul Islam ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Optic Neuritis ◽  
Clinical Diagnosis ◽  
Optic Neuropathy ◽  
Cross Sectional Study ◽  
P Value ◽  
Pattern Reversal ◽  
Cross Sectional ◽  
The Mean ◽  
Visual Evoked

Background: The visual evoked potentials (VEP) is a valuable tool to document occult lesions of the central visual channels especially within the optic nerve. Objectives: The purpose of the present study was to observe the findings of first few cases of VEP done in the neurophysiology department of the National Institute of Neurosciences (NINS), Dhaka, Bangladesh. Methodology: This cross-sectional study was conducted in the Department of Neurophysiology at the National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from September 2017 to March 2020. All patients referred to the Neurophysiology Department of NINS for VEP were included. Pattern reversal VEPs were done using standard protocol set by International Federation of Clinical Neurophysiology (IFCN). Results: The mean age of the study population was 30.70 (±12.11) years (6-68 years) with 31 (46.3%) male and 36 (53.7%) female patients. The mean duration of illness was 8.71 (±1.78) months (3 days- 120 months). Most common presenting symptom was blurring of vision (37.3%) and dimness of vision (32.8%). Patterned VEP revealed mixed type (both demyelinating and axonal) of abnormality in most cases [29(43.35)]. The most common clinical diagnosis was multiple sclerosis (29.85%) and optic neuropathy (26.87%). In the clinically suspected cases of multiple sclerosis, optic neuropathy and optic neuritis most of the cases of VEP were abnormal and the p value is 0.04 in optic neuropathy and optic neuritis. Conclusion: The commonest presentation of the patients in this series were blurring of vision and dimness of vision. The most common clinical diagnosis for which VEP was asked for, was optic neuritis and multiple sclerosis. Most abnormalities were of mixed pattern (demyelinating and axonal). Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 74-77

Sonographic Assessment of Amniotic Fluid Volume using Single Deepest Pocket (SDP) among Igbo Women with Uncomplicated Singleton Pregnancies.

2019 ◽  
Vol 2 (1) ◽  
pp. 1-18
Author(s):  
Chijioke Okeudo ◽  
B.U. Ezem
Keyword(s):  
Amniotic Fluid ◽  
Gestational Age ◽  
Cross Sectional Study ◽  
Fluid Volume ◽  
Singleton Pregnancy ◽  
Cross Sectional ◽  
South Eastern ◽  
Amniotic Fluid Volume ◽  
The Mean ◽  
Singleton Pregnancies

Background: The amniotic fluid is fundamental for proper fetal development and growth. Ultrasound visualization of the amniotic fluid permits both subjective and objective estimates of the amniotic fluid. Objective: The objective of this study was to determine the reference values of normal single deepest pocket (SDP) – upper and lower limits, mean SDP and variation of the SDP with gestational age among Igbo women of South-Eastern Nigeria extraction carrying uncomplicated singleton pregnancy. Methodology: This was a prospective cross sectional study involving 400 women carrying uncomplicated singleton pregnancies and who were sure of the date of the first day of their last menstrual period. The single deepest pocket / maximum vertical pool were determined once at presentation at the hospital.. The study was conducted from January 1st to December 31st 2015. The second author carried out all the scanning. The SDP was obtained. Results: The womens’ mean and median ages were the same at 28 years. The gestational age range of the pregnancies was 14-41 weeks. The mean SDP was 5.8cm, while the 5th and 95th percentiles were 3.3cm and 8.5cm respectively. There was no difference in the mean SDP in both term and preterm. There was irregular but continuous rise of mean SDP to a peak of 6.8cm at gestational age of 39 weeks. In conclusion, the participants had a mean SDP of 5.8cm. There was also a positive correlation between SDP and Gestational age. We therefore recommend a longitudinal study to assess perinatal outcome and abnormal amniotic fluid volume among Igbo women of South-Eastern Nigeria. Key words: Single Deepest Pocket, Uncomplicated Singleton Pregnancy, Igbo Women.

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