scholarly journals Prevalence, Risk Factors, and Molecular Detection of Campylobacter in Farmed Cattle of Selected Districts in Bangladesh

Pathogens ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 313
Author(s):  
Nazmul Hoque ◽  
SK Shaheenur Islam ◽  
Md. Nasir Uddin ◽  
Mohammad Arif ◽  
A. K. M. Ziaul Haque ◽  
...  
Keyword(s):  
Risk Factors ◽  
Molecular Detection ◽  
Significant Risk ◽  
Control Measures ◽  
P Value ◽  
Cross Sectional Survey ◽  
Herd Level ◽  
Farm Level ◽  
Level Data ◽  
Feces Sample

A cross-sectional survey was conducted in selected districts of Bangladesh to estimate prevalence, risk factors, and molecular detection of Campylobacter isolates from 540 farmed cattle of 90 herds. As an individual sample, 540 feces, and as a pooled sample, 180 milk samples, 90 feed samples, 90 water samples, 90 manure samples, and 90 animal attendants’ hand-rinse water were collected and tested via culture, biochemical, and molecular assays. A pretested semi-structured questionnaire was used to collect herd-level data on risk factors with the herd owners. The herd-level data on risk factors were analyzed through univariate and multivariate analyses, and a p-value <0.05 was considered statistically significant for all analyses. Overall, farm-level prevalence of bovine Campylobacter was enumerated to be 53.3% (95% confidence interval [CI]: 42.5–63.9%). The feces sample was found to be a high level of contamination of 30.9% (95% CI: 27–35%) followed by the manure swab (pooled) at 15.6% (95% CI: 8.8–24.7%). Campylobacter jejuni was documented as an abundant species (12.6%), followed by Campylobacter coli (5.1%), and Campylobacter fetus (0.3%). Older farms (>5 years of age), no/minimum cleaning and disinfection practices, along with animal roaming outside of the farm, were documented as significant risk factors for farm-level Campylobacter occurrence. Evidence-based control measures need to be taken through stringent biosecurity and hygienic measurement to lessen the load of the Campylobacter pathogen in the farm environment and prevent further transmission to animals and humans.

scholarly journals HAEMODIALYSIS;

2017 ◽  
Vol 24 (11) ◽  
pp. 1610-1614
Author(s):  
Aurangzeb Afzal ◽  
Sania Ashraf ◽  
Abubakar Raheel ◽  
Fateh Sher Chattah ◽  
Faiqa Zafar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
General Hospital ◽  
Significant Risk ◽  
Control Measures ◽  
Health Concern ◽  
Maintenance Hemodialysis ◽  
P Value ◽  
Infection Control Measures ◽  
Set Up

Background: Hepatitis C is an important health issue in chronic kidney diseasepatients especially those on regular hemodialysis. The cause of this high prevalence remainsmulti-factorial. Despite of various infection control measures adopted worldwide, hepatitis chigh seroconversion rates among dialysis patients remain a major health concern. Objectives:The objective of this study was to determine the frequency of seroconversion of hepatitis C inpatients on maintenance hemodialysis in our set-up and also to find the various risk factorsattributing to it. Study Design: Retrospective study. Place and duration of study: Hemodialysisunit of LAHORE GENERAL HOSPITAL since August, 2016. Methods: Forty seven patients onroutine hemodialysis who were initially sero negative for hepatitis C at the time of registrationin Lahore general hospital dialysis centre and frequency of seroconversion to positive for antiHCV was calculated using SPSS 20. The various variables were analyzed on basis of p-value(significant <0.05). Results: Out of total 47 patients, 6 patients (12.80%) were found to besero converted to hepatitis C during the dialysis treatment in our centre. History of surgicalprocedure (major/minor) (83.3%, p value:0.006) and presence of hepatitis C in spouse (66.7%,p value :0.0001) were found to be statistically significant risk factors. Conclusion: The currentstudy indicates the high rates of hepatitis C seroconversion in hemodialysis patients and thevarious contributing risk factors for it. Because of the immunodeficiency in these patients,intense education to medical staff as well as patients themselves will be beneficial in controllingthe spread.

scholarly journals An Investigation of Hypertension Risk Factors among Adults in Oshikoto Region in Namibia

2021 ◽  
Vol 13 (7) ◽  
pp. 115
Author(s):  
Emilia Shiwa Ashipala ◽  
Linda Ndeshipandula Lukolo
Keyword(s):  
Risk Factors ◽  
Significant Risk ◽  
Population Based ◽  
P Value ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Hypertension Risk ◽  
Obesity And Overweight ◽  
High Prevalence ◽  
Harmful Use

INTRODUCTION: Hypertension complications are responsible for 9.4 million deaths worldwide and among these deaths, 51 % are due to stroke and 45% are due to heart disease like heart failure. This study aims to investigate the hypertension risk factors among adult in Oshikoto region, Namibia. METHODS: A community population-based, cross- sectional survey was conducted using WHO STEPwise approach among 375 adults in Oshikoto region. Bivariate and multivariate analysis was done to determine the association between risk factors and Hypertension, based on p-value &lt;0.05. RESULTS: Overall prevalence for risk factors was: physical inactivity (25.3%), unhealthy diet (75.7%), tobacco use (9.1%), harmful use of alcohol (40.8%). 20.5% overweight with majority (85.7%) of them were females. Obesity was 9.1% in which 91.2% were females. Hypertension prevalence was 24.3%. Four percent of individuals were having two multiple risk factors for hypertension, 2.4% with four risk factors and 1.1% with more than four risk factors. Age group (OR=2.48, 95%CI=1.44-4.26, P=0.001), Obesity (OR=3.48, 95%CI=1.55-7.79, P=0.003), and overweight (OR=2.34, 95%CI=1.31-4.19, P =0.004) were significant risk factors for hypertension. CONCLUSIONS: This study revealed a high prevalence and burden of hypertension risk factors such as obesity and overweight among adults in Oshikoto region, thus, these results highlight the need for interventions to reduce and prevent those risk factors of hypertension in Oshikoto region, Namibia.

scholarly journals Determination of farm-level risk factors for abnormalities observed during post-mortem meat inspection of lambs: a feasibility study

1999 ◽  
Vol 123 (1) ◽  
pp. 109-119 ◽  
Author(s):  
D. S. EDWARDS ◽  
K. H. CHRISTIANSEN ◽  
A. M. JOHNSTON ◽  
G. C. MEAD
Keyword(s):  
Risk Factors ◽  
Liver Fluke ◽  
Significant Risk ◽  
Animal Husbandry ◽  
Significant Risk Factor ◽  
Meat Inspection ◽  
Post Mortem ◽  
Farm Level ◽  
Level Data ◽  
Health And Disease

To investigate the feasibility of using information about the health and management of lambs on farms to predict the risk of gross abnormalities at post-mortem meat inspection, 6732 lambs from 30 different farms in Great Britain were followed through to slaughter in 1995/6. The farm-level data were collected during farm visits at the beginning of the study. Routine meat inspection findings for the lambs were obtained from the 10 participating abattoirs. The most common abnormalities found during post-mortem inspection were pneumonia/pleurisy (53% of cohorts), lungworm (40%), abscesses (30%), liver fluke (27%) and nephritis/nephrosis (27%). The farm-level risk factors associated with abnormalities at slaughter varied with the type of lesion. The most significant risk factor was the age of the lambs at slaughter. Lambs slaughtered at an older age were more likely to have an abnormality, especially pneumonia, abscesses and liver fluke. After age, environmental factors appeared to be better predictors of those cohorts that would have lesions at slaughter than health and disease control variables. However, a much larger study would be required to identify a set of farm-level factors that adequately discriminated between lambs with high and low risks of lesion at slaughter. At the end of the study, the farmers were informed of the meat inspection findings for their lambs and a third indicated that they would improve their animal husbandry as a result of the information.

scholarly journals VENTILATOR ASSOCIATED PNEUMONIA IN TRAUMA PATIENTS; ASSOCIATED RISK FACTORS, MICROBIAL ETIOLOGY AND OUTCOME

2021 ◽  
Vol 71 (4) ◽  
pp. 1476-80
Author(s):  
Sohaima Manzoor ◽  
Farzana Batool ◽  
Muneeba Ahsan Sayeed ◽  
Azizullah Khan Dhiloo ◽  
Humera Muhammad Ismail ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Emergency Room ◽  
Therapeutic Option ◽  
Significant Risk ◽  
Control Measures ◽  
P Value ◽  
Trauma Patients ◽  
Ventilator Associated Pneumonia

Objective: To assess the incidence, risk factors and outcome of ventilator associated pneumonia in trauma patients. Study Design: Prospective observational study. Place and Duration of Study: Shaheed Mohtarma Benazir Bhutto Institute of Trauma, Karachi, from Jul to Dec 2019. Methodology: All trauma patients, above 12 years, placed on mechanical ventilation in the emergency room or intensive care unit, were enrolled. Patients that developed a clinical pulmonary infection score of less than 6 were diagnosed with ventilator associated pneumonia. Results: A total of 113 patients were enrolled in this study. Mean age was 32.9 ± 14.4 years. Thirty eight (33.6%) developed ventilator associated pneumonia. Patients with ventilator associated pneumonia, compared to non-ventilator associated pneumonia, had a longer emergency room stay of 7.8 ± 10.1 vs. 4.7 ± 7.4 days (p-value=0.013), greater ventilator days of 18.5 ± 12.6 vs. 7.9 ± 5.5 (p-value=0.001), longer hospital stay of >14 days in 65.8% vs. 33.3% (p-value=0.001) and higher mortality of 65.8% vs. 56% (p-value=0.213). Nurse to patient ratio and infection control measures for prevention of ventilator associated pneumonia were significantly reduced in emergency room compared to intensive care unit (p-value=0.001). Out of 43 respiratory isolates in 38 ventilator associated pneumonia patients, 40 (93%) were gram negatives of which 23 (57.5%) were multidrug resistant with polymyxins as the only therapeutic option. Conclusion: There was a high incidence of ventilator associated pneumonia in patients with trauma. Prolonged retention in the emergency room is a significant risk factor for ventilator associated pneumonia, due to understaffing..................

scholarly journals Trends in malaria prevalence and risk factors associated with the disease in Nkongho-mbeng; a typical rural setting in the equatorial rainforest of the South West Region of Cameroon

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251380
Author(s):  
Raymond Babila Nyasa ◽  
Esendege Luke Fotabe ◽  
Roland N. Ndip
Keyword(s):  
Risk Factors ◽  
Significant Risk ◽  
Control Measures ◽  
Rural Setting ◽  
Current Status ◽  
Effective Control ◽  
Cross Sectional Survey ◽  
Housing Type ◽  
Cross Sectional ◽  
Factors Associated

Globally, malaria in recent years has witnessed a decline in the number of cases and death, though the most recent world malaria report shows a slight decrease in the number of cases in 2018 compared to 2017 and, increase in 2017 compared to 2016. Africa remains the region with the greatest burden of the disease. Cameroon is among the countries with a very high burden of malaria, with the coastal and forest regions carrying the highest burden of the disease. Nkongho-mbeng is a typical rural setting in the equatorial rain forest region of Cameroon, with no existing knowledge of the epidemiology of malaria in this locality. This study aimed at determining the current status of malaria epidemiology in Nkongho-mbeng. A cross-sectional survey was conducted, during which blood samples were collected from 500 participants and examined by microscopy. Risk factors such as, age, sex, duration of stay in the locality, housing type, environmental sanitation and intervention strategies including use of, LLINs and drugs were investigated. Trends in malaria morbidity were also determined. Of the 500 samples studied, 60 were positive, giving an overall prevalence of 12.0% with the prevalence of asymptomatic infection (10.8%), more than quadruple the prevalence of symptomatic infections (1.2%) and, fever burden not due to malaria was 1.4%. The GMPD was 6,869.17 parasites/μL of blood (95% C.I: 4,977.26/μL– 9,480.19/μL). A LLINs coverage of 84.4% and 77.88% usage was observed. Unexpectedly, the prevalence of malaria was higher among those sleeping under LLINs (12.56%) than those not sleeping under LLINs (8.97%), though the difference was not significant (p = 0.371). Being a male (p = 0.044), being unemployed (p = 0.025) and, living in Mbetta (p = 0.013) or Lekwe (p = 0.022) and the presence bushes around homes (p = 0.002) were significant risk factors associated with malaria infection. Trends in proportion demonstrated that, the prevalence of malaria amongst patients receiving treatment in the health center from 2015 to 2019 decreased significantly (p < 0.001) and linearly from 9.74% to 3.08% respectively. Data generated from this study can be exploited for development of a more effective control measures to curb the spread of malaria within Nkongho-mbeng.

Prevalence and potential risk factors of hypocalcaemia in dairy cows during transition period at Northern Egypt

2020 ◽  
Vol 21 (1) ◽  
pp. 21-30 ◽  
Author(s):  
Hala Saed ◽  
Hussam Ibrahim ◽  
Sabry El-khodery ◽  
Mohamed Youssef
Keyword(s):  
Risk Factors ◽  
Dairy Cows ◽  
Transition Period ◽  
Body Condition Score ◽  
Dairy Herd ◽  
Clinical Mastitis ◽  
Control Measures ◽  
P Value ◽  
Farm Level ◽  
Serum Pth

Objective: To identify the most prevalent diseases of transition period in dairy cows and to highlight on risk factors supposed to play a crucial role in the prevalence of hypocalcaemia. Design: Case-control study Animals: 179 transition dairy cows belonged to five farms. Procedures: Clinical examination and serum analyses were the key to diagnose the transition disorders in the investigated cows. Cutoff points for serum analytes (Ca, Ph, Mg, PTH, glucose, K, Na and Cl) were set. A questionnaire was constructed to identify the possible risk factors associated with hypocalcaemia on both farm level and cow level. Results: Frequency test revealed the prevalence of hypocalcaemia to be (48.04%), hypophosphatemia (40.22%), hypomagnesaemia (33.52%) hypoglycemia (29.05%), hypokalemia (58.1%), clinical ketosis (5.59%) and abomasal displacement (1.12%). Moreover, prevalence of post parturient septic metritis was (26.81%), retained placenta (23.46%) and clinical mastitis was (18.99%). Generally, hypocalcaemia was significantly associated with other concurrent diseases (P ≤ 0.05). Levels of serum PTH, glucose, K and Na were significantly related to occurrence of hypocalcaemia with p values: 0.006, 0.001, 0.019 and 0.001, respectively. Impact of diet, housing criteria and periodical health monitoring by metabolic profile test were found to affect significantly on incidence of hypocalcaemia on farm level with p value ≤ 0.008 for all. On cow level, age of cows, parity, body condition score, stage of transition period, daily milk yield and previous transition period disorders were found to have a significant effect on occurrence of hypocalcaemia at p value ≤ 0.001 for each item. Conclusion and clinical relevance: Results of the current study point toward the importance of usual monitoring of transition period disorders in dairy cows, besides identifying potential risks and consequences of hypocalcaemia in an attempt to construct control measures for them, that in-turn would increase dairy herd profitability.

MEASLES OUTBREAK IN A RURAL AREA OF A DEVELOPING COUNTRY: A CASE CONTROL STUDY

2018 ◽  
Vol 7 (4) ◽  
pp. 197-201
Author(s):  
Mir M Hassan Bullo ◽  
Mirza Amir Baig ◽  
Jawad Faisal Malik ◽  
Ejaz Ahmad Khan ◽  
Muazam Abbas Ranjha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vaccine Coverage ◽  
Significant Risk ◽  
Public Health Problem ◽  
Maculopapular Rash ◽  
Healthcare Facility ◽  
Control Measures ◽  
Major Public Health Problem ◽  
District Health ◽  
Active Case

Background: Measles is highly contagious vaccine preventable disease (VPD), and a major public health problem considered as leading cause of morbidity and mortality in developing countries like Pakistan. An outbreak of measles was reported in Sharifabad Islamabad on 15th of April 2017, and an investigation was launched to assess the magnitude of outbreak, evaluate risk factors and recommend control measures. Methods: A comprehensive house to house active case search along with vaccine coverage survey was conducted from April 19-22, 2017. A case was defined as "onset of maculopapular rash with fever in a resident of Sharifabad with at least one of the following signs/ symptoms, Coryza, Conjunctivitis, Cough, Otitis media or Pneumonia present in between 19 March to 22nd April 2017". Four age & sex matched controls were selected from the neighborhood. Data was collected through interview method using structured questionnaire and vaccination coverage was determined by using Epi survey form. Blood samples were sent for laboratory confirmation. Results: A total of eight cases were identified through active case finding while three were reported by local practitioner. Mean age of cases were 20 months (range 8-36 months). Severely affected age-group was 1-2 years with attack rate of 46%. Around two-third (64%) of cases and a few (16%) of controls were unvaccinated against measles. Contact with measles patient [OR 25.2, CI 3.9-160.1, P=0.00], unvaccinated children [OR 9.2 CI 2.12-40.4, P=0.000], social misconception regarding vaccination [OR 7.8 CI 1.42-42.6, P=0.00], and distance from healthcare facility [OR 5.7 CI 1.15-28.35, P=0.02] were significant risk factors. Vaccine efficacy was 90%. Conclusion: Main reasons of the outbreak were contact with the cases, and low vaccination status. We recommended comprehensive measles vaccination and community awareness sessions. On our recommendations district health authority Islamabad carried out mop up of whole area.

Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia

Parasitology ◽  
2019 ◽  
Vol 146 (12) ◽  
pp. 1602-1614 ◽  
Author(s):  
Hesham M. Al-Mekhlafi ◽  
Nabil A. Nasr ◽  
Yvonne A. L. Lim ◽  
Fatin Nur Elyana ◽  
Hany Sady ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intestinal Parasites ◽  
Agar Plate ◽  
Significant Risk ◽  
Control Programme ◽  
Control Measures ◽  
Parasitic Infections ◽  
Cross Sectional ◽  
Orang Asli ◽  
Direct Smear

AbstractThis cross-sectional study aimed to determine the prevalence and risk factors of S. stercoralis infection among 1142 Orang Asli primary schoolchildren in six different states of Peninsular Malaysia. Fecal samples were examined using direct smear, formalin-ether sedimentation (FES), agar plate culture (APC) and PCR techniques. Overall, 15.8% of the children were found to be infected with S. stercoralis. The prevalence was 0.2, 1.3, 15.2 and 13.7% by direct smear, FES, APC and PCR, respectively. Multivariate analysis showed that an age of >10 years, being male, belonging to a Proto-Malay tribe, belonging to the Senoi tribe, indiscriminate defecation, using an unimproved water source for drinking water and not wearing shoes when outside were the significant risk factors of infection among these children. In conclusion, we provide new evidence on the occurrence of S. stercoralis in Malaysia to show that there is a relatively high prevalence of infection among Orang Asli schoolchildren. Therefore, the use of specific methods for detecting S. stercoralis should be considered when screening these children for intestinal parasites. Moreover, prevention and control measures specific to S. stercoralis should be integrated into the intestinal parasitic infections control programme in Malaysia.

Risk Factors Associated With Dengue Fever Outbreak in Taiz Governorate, Yemen, 2018: Case-control Study

2021 ◽  
Author(s):  
Abdulkareem Ali Hussein Nassar ◽  
Amr Abdulaziz Torbosh ◽  
Yassin Abdulmalik Mahyoub ◽  
Mohammed Abdullah Al Amad
Keyword(s):  
Risk Factors ◽  
Dengue Fever ◽  
Case Control Study ◽  
Significant Risk ◽  
Case Fatality ◽  
Case Control ◽  
Case Definition ◽  
P Value ◽  
Factors Associated ◽  
Control Study

Abstract Background: Dengue Fever (DF) is a significant health problem in Yemen especially in the coastal areas. On November 6, 2018, Taiz governorates surveillance officer notified the Ministry of Public Health and Population on an increase in the number of suspected DF in Al Qahirah and Al Mudhaffar districts, Taiz governorate. On November 7, 2018, Field Epidemiology Training Program sent a team to perform an investigation. The aims were to confirm and describe the outbreak by person, place and time in Taiz governorate, and identify its risk factors.Methodology: Descriptive and case-control study (1:2 ratio) were conducted. WHO case definition was used to identify cases in Al Qahirah or Al Mudhaffar districts during August-November 2018. Control was selected from the same districts who did not suffer from DF. Predesigned questionnaire was used to collect data related to sociodemographic, behavioral and environmental characteristics. Bivariate and multivariate backward stepwise analyses were used. The adjusted odds ratios (aOR) and 95% confidence intervals (95%CI) were calculated. A P value < 0.05 was considered as the cut point for statistically significant. Epi info version 7.2 was used.Results: A total of 50 DF cases were found. Almost 52% were males and 76% were <30 years of age. The overall attack rate was 1/10,000 of the population. Case fatality rate was 4%. In multivariate analysis, not working (aOR = 26.6, 95% CI: 6.8–104.7), not using mosquito repellent (aOR = 13.9, 95% CI:1.4–136.8), wearing short sleeves/pants (aOR = 27.3, 95% CI: 4.8–156.8), poor sanitation (aOR = 5.4, 95% CI: 1.4–20.3), presence of outdoor trees (aOR = 13.2, 95% CI: 2.8–63.0) and houses without window nets (aOR = 15.7, 95% CI: 3.9–63.4) were statistically significant risk factors associated with DF outbreak. Eleven 11 (58%) of blood samples were positive for DF IgM.Conclusions: DF outbreak in Al Qahirah and Al Mudhaffar districts, Taiz governorate was confirmed. This study provides evidence-based information regarding the identified risk factors that contributed to the occurrence of this outbreak. Raising community awareness on the importance of personal protection measures and improving the sanitation services are strongly recommended.

scholarly journals Incidence and Risk Factors of Recipient Surgical Site Infection in Oral and Maxillofacial Reconstruction with Vascularized Fibular Bone Grafts

2020 ◽  
pp. 231
Author(s):  
Pichai Vittayakittipong ◽  
Sarocha Makmanee
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Significant Risk ◽  
Bone Grafts ◽  
Class Ii ◽  
P Value ◽  
Site Infection ◽  
Physical Status ◽  
Recipient Site ◽  
Maxillofacial Reconstruction

Objective: To determine the incidence and risk factors of recipient surgical site infection (RSSI) after oral and maxillofacial reconstruction with vascularized fibular bone grafts (VFBG).Material and Methods: This retrospective study was performed in patients who underwent oral and maxillofacial reconstructive surgery, with VFBG, at the Dental Hospital, Faculty of Dentistry, Prince of Songkla University. Demographic, preoperative, intraoperative and postoperative data were recorded. Any infection at the recipient site occurring within 30 days post-operatively, by criteria from the Center of Disease Control, was defined as RSSI. Statistical analysis was performed by chi-square test, Student's t-test and Pearson’s correlation coefficient with statistical significance was set at 0.05.Results: There were twenty-one patients who met the eligibility criteria. The incidence of RSSI after oral and maxillofacial reconstruction with VFBG was 47.6% (10/21 patients), and the success rate of VFBG was 95.2%. American Society of Anesthetics (ASA) physical status class II and oral contamination were significant risk factors for RSSI (p-value=0.004 and p-value=0.031, respectively). Length of hospital stay was significantly higher in the RSSI group (p-value<0.001).Conclusion: The incidence of RSSI after oral and maxillofacial reconstruction with VFBG was high, and ASA physical status class II and oral contamination were significant risk factors for RSSI.

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