scholarly journals Chemical Profile and Biological Activities of Essential Oil from Artemisia vulgaris L. Cultivated in Brazil

2019 ◽  
Vol 12 (2) ◽  
pp. 49 ◽  
Author(s):  
Sonia Malik ◽  
Ludmilla de Mesquita ◽  
Carolina Silva ◽  
José de Mesquita ◽  
Emmeline de Sá Rocha ◽  
...  

Essential oil from the leaves of Artemisia vulgaris L. (Compositae) cultivated in Brazil was investigated for its chemical composition and biological activities including antibacterial, antifungal, and anthelmintic. The constituents of essential oils isolated by hydro-distillation were examined by GC-MS and a total of 18 components were identified. The essential oil was dominated by oxygenated sesquiterpenes (44.4%), sesquiterpene hydrocarbons (33.3%), and oxygenated monoterpenes (16.6%). Caryophyllene (37.45%), germacrene D (16.17%), and humulene (13.66%) were the major components. The essential oils from A. vulgaris showed bactericidal and fungicidal properties against Staphylococcus aureus and Candida albicans, respectively. Anthelmintic activity against Haemonchus contortus was absent in this essential oil. Altogether above results indicate that essential oils from A. vulgaris can be used for various medicinal purposes.

2018 ◽  
Vol 13 (7) ◽  
pp. 1934578X1801300
Author(s):  
Biljana Nikolić ◽  
Milić Matović ◽  
Marina Todosijević ◽  
Jovana Stanković ◽  
Mirjana Cvetković ◽  
...  

Terpene compounds of Tanacetum macrophyllum as 1) essential oils, obtained by hydrodistillation (HD), 2) essential oil extracts, obtained by simultaneous hydrodistillation and extraction (SDE) and 3) volatiles, obtained by Static Headspace GC-MS analysis (HS) were processed. Monoterpenes were the most dominant (49.2%, 49.5% and 90.4%, respectively). Profiles of essential oils obtained by HD and SD were quite similar, with oxygenated monoterpenes (39.3% and 39.4%) being the most abundant. In HS volatiles oxygenated monoterpenes also dominated (57.4%). Total sesquiterpenes were abundant in HD and SDE volatiles (38.2% and 39.2%, resp.), where sesquiterpene hydrocarbons were prevalent (27.3% and 28.7%, resp.). Germacrene D was dominant in HD and SDE oils (22.0% and 23.3%, resp.) and 1,8-cineole in HS volatiles (34.3%). To our knowledge, this is the first use of Headspace technique on T. macrophyllum. Furthermore, this is the first comparison of different techniques of volatile extraction in T. macrophyllum.


2010 ◽  
Vol 75 (10) ◽  
pp. 1361-1368 ◽  
Author(s):  
M.B. Hassanpouraghdam ◽  
G.R. Gohari ◽  
S.J. Tabatabaei ◽  
M.R. Dadpour

In order to characterize the essential oils of leaves and inflorescences, water distilled volatile oils of hydroponically grown Ocimum basilicum L. were analyzed by GC/EI-MS. Fifty components were identified in the inflorescence and leaf essential oils of the basil plants, accounting for 98.8 % and 99.9 % of the total quantified components respectively. Phenylpropanoids (37.7 % for the inflorescence vs. 58.3 % for the leaves) were the predominant class of oil constituents, followed by sesquiterpenes (33.3 % vs. 19.4 %) and monoterpenes (27.7 % vs. 22.1 %). Of the monoterpenoid compounds, oxygenated monoterpenes (25.2 % vs. 18.9 %) were the main subclass. Sesquiterpene hydrocarbons (25 % vs. 15.9 %) possessed the main subclass of sesquiterpenoidal compounds as well. Methyl chavicol, a phenylpropane derivative, (37.2 % vs. 56.7 %) was the principle component of both organ oils, with up to 38 % and 57 % of the total identified components of the inflorescence and leaf essential oils, respectively. Linalool (21.1 % vs. 13.1 %) was the second common major component followed by ?-cadinol (6.1 % vs. 3 %), germacrene D (6.1 % vs. 2.7 %) and 1,8-cineole (2.4 % vs. 3.5 %). There were significant quantitative but very small qualitative differences between the two oils. In total, considering the previous reports, it seems that essential oil composition of hydroponically grown O. basilicum L. had volatile constituents comparable with field grown counterparts, probably with potential applicability in the pharmaceutical and food industries.


2013 ◽  
Vol 8 (10) ◽  
pp. 1934578X1300801 ◽  
Author(s):  
Prajwal Paudel ◽  
Prabodh Satyal ◽  
Noura S. Dosoky ◽  
Samjhana Maharjan ◽  
William N. Setzer

The essential oils from the leaves of Juglans regia, collected from Kathmandu, Nepal, and Juglans nigra from Huntsville, Alabama, USA, were obtained by hydrodistillation and analyzed by GC-MS. A total of 69 compounds were identified in the J. regia oil, accounting for 99.0% of the eluting components of the oil while three different samples of J. nigra were analyzed identifying a total of 99.3%, 99.4% and 99.7% of the oils. The leaf essential oil of J. regia was dominated by the aromatic compounds eugenol (27.5%) and methyl salicylate (16.2%), and the sesquiterpenes germacrene D (21.4%) and ( E)-β-farnesene (8.2%). The essential oils from three different samples of J. nigra contained ( E)-caryophyllene (17.3%–20.4%) and germacrene D (7.1%–22.5%) with smaller amounts of juglone (1.0%–8.8%), α-hydrojuglone (1.0–9.5%), and δ-cadinene (3.8%–8.7%). J. regia leaf oil, devoid of juglone, showed allelopathic activity, while J. nigra leaf oil was less phytotoxic. The presence of eugenol and methyl salicylate in the leaves of J. regia are consistent with the traditional uses of this plant to treat toothache, rheumatism, and fungal infections.


2021 ◽  
Vol 16 (9) ◽  
pp. 1934578X2110320
Author(s):  
Ninh T. Son ◽  
Tuan A. Le ◽  
Dinh T. T. Thuy ◽  
Dinh L. Nguyen ◽  
Tran T. Tuyen ◽  
...  

Plants of the genus Polyalthia can be seen as a rich resource of essential oils type terpenoids. In this study, the essential oils obtained by hydro-distillation from the leaf and stem of Polyalthia viridis were analysed by gas chromatography/mass spectrometry–flame ionization detection. Thirty-nine constituents (95.3%) were identified in the leaf oils and 42 constituents (90.9%) in the stem oils. Sesquiterpene hydrocarbons and oxygenated sesquiterpenes were the main constituents of both oils, in which 2 sesquiterpene hydrocarbons, germacrene D (45.1%-47.4%) and bicyclogermacrene (8.2%-17.1%), were the 2 major compounds. The stem oils inhibited the growth of 3 cancer cell lines, HepG2, MCF7, and A549, with half inhibitory concentration (IC50) values of 56.7 to 68.4 μg/mL. The stem oils also successfully suppressed the growth of the filamentous fungus Aspergillus niger and the yeast Candida albicans with minimum inhibitory concentration values of 50 μg/mL. P viridis oils suppressed NO production in lipopolysaccharide-stimulated BV2 microglial cells, with IC50 values of 57.6 to 76.7 μg/mL.


2013 ◽  
Vol 8 (2) ◽  
pp. 1934578X1300800
Author(s):  
Igor Jerković ◽  
Maja Marasović ◽  
Zvonimir Marijanović ◽  
Kroata Hazler Pilepić ◽  
Željan Maleš ◽  
...  

The aerial parts of Hypericum richeri Vill. subsp. grisebachii (Boiss.) Nyman were collected from two different locations in Croatia and subjected to hydrodistillation. GC/FID and GC/MS analysis of the isolated essential oils revealed 64 compounds representing 94.7% and 98.2% of the total oils. Predominant constituents in both samples were: germacrene D (10.9%; 6.0%), bicyclogermacrene (4.7%; 3.5%), α-pinene (6.8%; 6.9%), β-pinene (8.1%; 5.1%), decanoic acid (4.5%; 6.8%), β-caryophyllene (3.3%; 7.5%), δ-cadinene (7.0%; 4.4%), spathulenol (6.0%; 9.5%) and tetracosane (3.1%; 5.8%). Comparison of both samples revealed similarity in the chemical composition with minor fluctuations of constituent percentages. The chemical profile of Croatian oils was in general similar to those reported for other geographic areas regarding major mono- and sesquiterpene constituents. However, spathulenol, 5-cadinene and bicyclogermacrene were more abundant in Croatian oils. The presence of decanoic acid (4.5%; 6.8%) in Croatian oils was the major difference between acids and fatty acids derivatives. Higher abundance of alkanes (particularly tetracosane and docosane) was also noticed.


2020 ◽  
Vol 42 ◽  
pp. e51639
Author(s):  
Beatriz Eugenia Jaramillo-Colorado ◽  
Flor María Palacio-Herrera ◽  
Edisson Duarte-Restrepo

 The objectives of this work were the study of the volatile chemical composition of essential oils (EO’s) from Swinglea glutinosa, as well as to evaluate their antioxidant, repellent and fumigant properties. The EO was obtained by hydrodistillation from the peel of the fruit, gathered in the city of Cartagena, Bolívar (Colombia). The volatile composition was analyzed by gas chromatography coupled to mass spectrometry (GC-MS). The major compounds found in S. glutinosa were germacrene D (4.8%), limonene (5.2%), a-terpineol (6.5%), b-pinene (8.5%), nerolidyl acetate (9.8%), and trans-nerolidol (34.6%). S. glutinosa showed antioxidant potential (85.8%) (IC50=142.49 µg mL-1). The EO deployed repellent activity against the Tribolium castaneum weevil at a concentration of 15.73 nL cm-1 at 2 hours of exposure (72%), while the result for the commercial repellent was 50% at the same concentration. EO from S. glutinosa displayed the best fumigant activity with LC50 of 153.4 μg mL-1 air. The essential oil from S. glutinosa can be considerated as a natural source of biocides and antioxidants.


2010 ◽  
Vol 5 (6) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Lalit Mohan ◽  
Charu C. Pant ◽  
Anand B. Melkani ◽  
Vasu Dev

Teucrium royleanum Wall ex. Benth. and T. quadrifarium Buch.-Ham., growing wild in the Central Himalayan region of Uttarakhand (India), yielded, on steam distillation, 0.07% and 0.09%, respectively of essential oil. The oil samples were analyzed by GC and GC-MS. By GC, both oil samples showed remarkable similarity with respect to the major peaks. Fifty-seven constituents were identified in both the oils representing 96.0% and 96.6% of the total, respectively. The oils were rich in sesquiterpene hydrocarbons (~76.0%). β-Caryophyllene (23.6% and 38.3%), germacrene D (28.9% and 9.4%), α-humulene (5.7% and 5.9%), linalool (4.8% and 1.5%), and 1-octen-3-ol (8.5% and 0.7%) were common to both oils and were the principal constituents. The genus can be classified into two groups on the basis of the present and previous reports on the essential oil composition and chemical markers.


2009 ◽  
Vol 4 (2) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Justin D. Richmond ◽  
Brittany R. Agius ◽  
Brenda S. Wright ◽  
William A. Haber ◽  
Debra M. Moriarity ◽  
...  

The leaf essential oils of Dendropanax capillaris, Oreopanax nubigenus and Schefflera rodrigueziana (Araliaceae) were isolated by hydrodistillation and analyzed by GC-MS. The leaf oil of Dendropanax capillaris was composed of only four compounds, β-pinene (25.3%), δ-3-carene (44.7%), daucene (17.1%), and dauca-5,8-diene (12.9%). Oreopanax nubigenus leaf oil was dominated by the sesquiterpene hydrocarbons germacrene D (70.1%) and β-caryophyllene (11.8%), while Schefflera rodrigueziana leaf oil was made up entirely of sesquiterpene hydrocarbons, mostly germacrene D (27.6%), β-cubebene (27.2%), β-caryophyllene (12.2%), α-cubebene (11.1%), and α-copaene (10.8%). Both O. nubigenus and S. rodrigueziana leaf oils showed notable in-vitro cytotoxicity on MDA-MB-231 cells, which may be attributable to the relatively high concentrations of germacrene D and β-caryophyllene in those oils.


Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3943 ◽  
Author(s):  
Valtcho D. Zheljazkov ◽  
Vladimir Sikora ◽  
Ivanka B. Semerdjieva ◽  
Miroslava Kačániová ◽  
Tess Astatkie ◽  
...  

The hypothesis of this study was that we can modify the essential oil (EO) profile of hemp (Cannabis sativa L.) and obtain fractions with differential composition and antimicrobial activity. Therefore, the objective was to evaluate the effects of grinding of hemp biomass before EO extraction and fractionation during distillation on EO profile and antimicrobial activity. The study generated a several EO fractions with a diversity of chemical profile and antimicrobial activity. The highest concentrations of β-pinene and myrcene in the EO can be obtained in the 5–10 min distillation time (DT) of ground material or in the 80–120 min DT of nonground material. High δ-3-carene and limonene EO can be obtained from 0–5 min DT fraction of nonground material. High eucalyptol EO can be sampled either in the 0–5 min DT of the ground material or in the 80–120 min of nonground material. Overall, the highest concentrations of β-caryophyllene, α-(E)-bergamotene, (Z)-β-farnesene, α-humulene, caryophyllenyl alcohol, germacrene D-4-ol, spathulenol, caryophyllene oxide, humulene epoxide 2, β-bisabolol, α-bisabolol, sesquiterpenes, and cannabidiol (CBD) can be obtained when EO is sampled in the 80–120 min DT and the material is nonground. Monoterpenes in the hemp EO can be increased twofold to 85% by grinding the material prior to distillation and collecting the EO in the first 10 min. However, grinding resulted in a slight but significant decrease in the CBD concentration of the EO. CBD-rich oil can be produced by collecting at 120–180 min DT. Different EO fractions had differential antimicrobial activity. The highest antimicrobial activity of EO fraction was found against Staphylococcus aureus subsp. aureus. THC-free EO can be obtained if the EO distillation is limited to 120 min. The results can be utilized by the hemp processing industry and by companies developing new hemp EO-infused products, including perfumery, cosmetics, dietary supplements, food, and pharmaceutical industries.


2018 ◽  
Vol 18 (3-4) ◽  
pp. 195-203
Author(s):  
Y.N. Otaifah ◽  
A. Bouyahya ◽  
A. Talbaoui ◽  
H. Harhar ◽  
S. El Hajjaji

Medicinal plants have been used since time immemorial to fight against diseases. The biological activities of these plants may be due to the presence of bioactive compounds such as essential oils. The aim of this study was to determine the chemical composition of three Yemen medicinal plants, and e evaluate their antibacterial and antioxidant activities. The chemical composition of essential oils was determined using gas chromatography–mass spectrometry (GC–MS) analysis. The antibacterial effect was evaluated against pathogenic bacterial strains using the micro-platoon method and the antioxidant activity was estimated by DPPH (2,2-diphenyl-1-picrylhydrazyl) scanning radical assay. Essential oils (EOs) are rich in phenolic compound. Carvotanacetone is the main compound of Pulicaria jaubertii (PJ) essential oil (82.35%) and β-maaliene (64.94%) is the major compound of Plectranthus montanus Benth (PMB) essential oil, while, Tarchonanthus camphoratus (TC) essential oil possesses several main compounds such as fenchol (14.5%), α-pinene (12.43%), and α-terpineol (8.58%). Essential oils of PJ and PMB showed remarkable antibacterial effect against Staphylococcus aureus (minimum inhibitory concentration, MIC = 0.25% [v/v]), and PJEO against Escherichia coli (MIC = 0.25%[v/v]); the lowestMBC (minimum bactericidal concentration) values was obtained with PJEO against Staphylococcus aureus (CMI = 0.25% [v/v]). TCEO interestingly showed capacity while scanning the DPPH radical (6.32 mg E Trolox). These findings showed the biological potential of Yemeni aromatic medicinal plants as antibacterial and antioxidant agents. However, further investigations are needed to determine the antibacterial and antioxidant mechanisms of these oils.


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