scholarly journals Towards a Resilience to Stress Index Based on Physiological Response: A Machine Learning Approach

Sensors ◽  
2021 ◽  
Vol 21 (24) ◽  
pp. 8293
Author(s):  
Ramon E. Diaz-Ramos ◽  
Daniela A. Gomez-Cravioto ◽  
Luis A. Trejo ◽  
Carlos Figueroa López ◽  
Miguel Angel Medina-Pérez
Keyword(s):  
Machine Learning ◽  
Euclidean Distance ◽  
Dimensional Space ◽  
Stress Test ◽  
Supervised Machine Learning ◽  
Stress Index ◽  
Cluster Validity Index ◽  
Physiological Variables ◽  
Significant Difference ◽  
Biofeedback Device

This study proposes a new index to measure the resilience of an individual to stress, based on the changes of specific physiological variables. These variables include electromyography, which is the muscle response, blood volume pulse, breathing rate, peripheral temperature, and skin conductance. We measured the data with a biofeedback device from 71 individuals subjected to a 10-min psychophysiological stress test. The data exploration revealed that features’ variability among test phases could be observed in a two-dimensional space with Principal Components Analysis (PCA). In this work, we demonstrate that the values of each feature within a phase are well organized in clusters. The new index we propose, Resilience to Stress Index (RSI), is based on this observation. To compute the index, we used non-supervised machine learning methods to calculate the inter-cluster distances, specifically using the following four methods: Euclidean Distance of PCA, Mahalanobis Distance, Cluster Validity Index Distance, and Euclidean Distance of Kernel PCA. While there was no statistically significant difference (p>0.01) among the methods, we recommend using Mahalanobis, since this method provides higher monotonic association with the Resilience in Mexicans (RESI-M) scale. Results are encouraging since we demonstrated that the computation of a reliable RSI is possible. To validate the new index, we undertook two tasks: a comparison of the RSI against the RESI-M, and a Spearman correlation between phases one and five to determine if the behavior is resilient or not. The computation of the RSI of an individual has a broader scope in mind, and it is to understand and to support mental health. The benefits of having a metric that measures resilience to stress are multiple; for instance, to the extent that individuals can track their resilience to stress, they can improve their everyday life.

scholarly journals Optimizing sizing schedules of aircrew helmets using machine learning techniques

2020 ◽  
Vol 64 ◽  
pp. 18-22
Author(s):  
P Biswal ◽  
SG Swamy
Keyword(s):  
Machine Learning ◽  
Head Length ◽  
Supervised Machine Learning ◽  
Machine Learning Techniques ◽  
Naturally Occurring ◽  
Several Variables ◽  
Learning Techniques ◽  
Head Breadth ◽  
Significant Difference ◽  
Sizing System

Introduction: Aircrew equipment assemblies are life critical equipment worn by the aircrew to ensure protection from various life-threatening environmental conditions that may occur in nominal or off-nominal flight conditions. It is important for the sizing system of body worn aircrew equipment to be divided into different size classes such that it is as representative of existing groups in the population as feasible. Machine learning techniques provide a powerful tool to develop efficient sizing systems that are representative of actual body types existing in the population. The objective of the study was to use machine learning clustering techniques to identify naturally existing body types to formulate an optimal sizing system for an aircrew helmet. Material and Methods: The standard sizing schedule of an aircrew helmet using head length and head breadth was studied. An iterative semi-supervised machine learning protocol called K-means clustering was used to identify naturally occurring clusters of head types within the population. The cluster boundaries were identified to develop the final sizing schedule. Analysis of variance (ANOVA) with post hoc analysis was carried out on the four head lengths and head breadths. Results: Four clusters of head type were identified using K-means clustering. This led to a sizing schedule which can be descriptively called “Short-Narrow,” “Short-Broad,” “Long-Narrow,” “Long-Broad.” ANOVA showed a statistically significant difference between the four clusters for both head length and head breadth. Conclusion: Consideration of several variables in sizing schedules often fails to meet desired fitment. Standard sizing methods use linear partitions on individual control parameters. In reality, the proportional variation between parameters is not linear. Machine learning tools help in identification of naturally occurring clusters within the database considering several variables at the same time. This study uses machine learning techniques to identify existing groups in a population and develop a final sizing schedule. Similar analysis for other aircrew equipment assemblies can be carried out to determine sizing schedules which assist in design and fitment.

scholarly journals HYPERSPECTRAL HYPERION IMAGERY ANALYSIS AND ITS APPLICATION USING SPECTRAL ANALYSIS

2015 ◽  
Vol XL-3/W2 ◽  
pp. 169-175 ◽  
Author(s):  
W. Pervez ◽  
S. A. Khan ◽  
Valiuddin
Keyword(s):  
Machine Learning ◽  
Vegetation Index ◽  
Hyperspectral Image ◽  
Atmospheric Correction ◽  
Hyperspectral Data ◽  
Supervised Machine Learning ◽  
Spectral Signature ◽  
Processing Application ◽  
Significant Difference

Rapid advancement in remote sensing open new avenues to explore the hyperspectral Hyperion imagery pre-processing techniques, analysis and application for land use mapping. The hyperspectral data consists of 242 bands out of which 196 calibrated/useful bands are available for hyperspectral applications. Atmospheric correction applied to the hyperspectral calibrated bands make the data more useful for its further processing/ application. Principal component (PC) analysis applied to the hyperspectral calibrated bands reduced the dimensionality of the data and it is found that 99% of the data is held in first 10 PCs. Feature extraction is one of the important application by using vegetation delineation and normalized difference vegetation index. The machine learning classifiers uses the technique to identify the pixels having significant difference in the spectral signature which is very useful for classification of an image. Supervised machine learning classifier technique has been used for classification of hyperspectral image which resulted in overall efficiency of 86.6703 and Kappa co-efficient of 0.7998.

Exploring the Use of Machine Learning to Automate the Qualitative Coding of Church-related Tweets

2020 ◽  
Vol 14 (2) ◽  
pp. 140-159
Author(s):  
Anthony-Paul Cooper ◽  
Emmanuel Awuni Kolog ◽  
Erkki Sutinen
Keyword(s):  
Machine Learning ◽  
Online Community ◽  
High Volume ◽  
Machine Learning Algorithms ◽  
Supervised Machine Learning ◽  
Social Media Data ◽  
Twitter Data ◽  
Resource Intensity ◽  
Media Data ◽  
Better Than

This article builds on previous research around the exploration of the content of church-related tweets. It does so by exploring whether the qualitative thematic coding of such tweets can, in part, be automated by the use of machine learning. It compares three supervised machine learning algorithms to understand how useful each algorithm is at a classification task, based on a dataset of human-coded church-related tweets. The study finds that one such algorithm, Naïve-Bayes, performs better than the other algorithms considered, returning Precision, Recall and F-measure values which each exceed an acceptable threshold of 70%. This has far-reaching consequences at a time where the high volume of social media data, in this case, Twitter data, means that the resource-intensity of manual coding approaches can act as a barrier to understanding how the online community interacts with, and talks about, church. The findings presented in this article offer a way forward for scholars of digital theology to better understand the content of online church discourse.

Mol2vec: Unsupervised Machine Learning Approach with Chemical Intuition

2017 ◽  
Author(s):  
Sabrina Jaeger ◽  
Simone Fulle ◽  
Samo Turk
Keyword(s):  
Machine Learning ◽  
Language Processing ◽  
Supervised Machine Learning ◽  
Learning Approach ◽  
Learning Approaches ◽  
Unsupervised Machine Learning ◽  
Feature Representations ◽  
Machine Learning Approach ◽  
The Individual ◽  
Vector Representations

Inspired by natural language processing techniques we here introduce Mol2vec which is an unsupervised machine learning approach to learn vector representations of molecular substructures. Similarly, to the Word2vec models where vectors of closely related words are in close proximity in the vector space, Mol2vec learns vector representations of molecular substructures that are pointing in similar directions for chemically related substructures. Compounds can finally be encoded as vectors by summing up vectors of the individual substructures and, for instance, feed into supervised machine learning approaches to predict compound properties. The underlying substructure vector embeddings are obtained by training an unsupervised machine learning approach on a so-called corpus of compounds that consists of all available chemical matter. The resulting Mol2vec model is pre-trained once, yields dense vector representations and overcomes drawbacks of common compound feature representations such as sparseness and bit collisions. The prediction capabilities are demonstrated on several compound property and bioactivity data sets and compared with results obtained for Morgan fingerprints as reference compound representation. Mol2vec can be easily combined with ProtVec, which employs the same Word2vec concept on protein sequences, resulting in a proteochemometric approach that is alignment independent and can be thus also easily used for proteins with low sequence similarities.

Application of Machine Learning Techniques to Predict Binding Affinity for Drug Targets: A Study of Cyclin-Dependent Kinase 2

2020 ◽  
Vol 28 (2) ◽  
pp. 253-265 ◽  
Author(s):  
Gabriela Bitencourt-Ferreira ◽  
Amauri Duarte da Silva ◽  
Walter Filgueira de Azevedo
Keyword(s):  
Machine Learning ◽  
Binding Affinity ◽  
Predictive Performance ◽  
Supervised Machine Learning ◽  
Machine Learning Techniques ◽  
Scoring Functions ◽  
Cyclin Dependent Kinase ◽  
Learning Models ◽  
Learning Techniques ◽  
Machine Learning Models

Background: The elucidation of the structure of cyclin-dependent kinase 2 (CDK2) made it possible to develop targeted scoring functions for virtual screening aimed to identify new inhibitors for this enzyme. CDK2 is a protein target for the development of drugs intended to modulate cellcycle progression and control. Such drugs have potential anticancer activities. Objective: Our goal here is to review recent applications of machine learning methods to predict ligand- binding affinity for protein targets. To assess the predictive performance of classical scoring functions and targeted scoring functions, we focused our analysis on CDK2 structures. Methods: We have experimental structural data for hundreds of binary complexes of CDK2 with different ligands, many of them with inhibition constant information. We investigate here computational methods to calculate the binding affinity of CDK2 through classical scoring functions and machine- learning models. Results: Analysis of the predictive performance of classical scoring functions available in docking programs such as Molegro Virtual Docker, AutoDock4, and Autodock Vina indicated that these methods failed to predict binding affinity with significant correlation with experimental data. Targeted scoring functions developed through supervised machine learning techniques showed a significant correlation with experimental data. Conclusion: Here, we described the application of supervised machine learning techniques to generate a scoring function to predict binding affinity. Machine learning models showed superior predictive performance when compared with classical scoring functions. Analysis of the computational models obtained through machine learning could capture essential structural features responsible for binding affinity against CDK2.

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