Biological feedback for support reaction and changing of its depth in the rehabilitation of patients after radical mastectomy

2020 ◽  
pp. 9-18
Author(s):  
A. V. Deeva ◽  
I. S. Evstigneeva ◽  
M. Yu. Gerasimenko

Objective. The study deals the influence of different biofeedback (BFB) depth for support reaction on the performance of a short course (3 sessions) for a motor-cognitive training of static and dynamic types in the rehabilitation of patients after a radical mastectomy. Subjects and methods. 21 patients between the ages of 40 and 74 years after radical mastectomy for breast cancer (BC) were examined and performed rehabilitation with the BFB depth for support reaction with a change normal sensitiveness of the force platform by 15, 30, 45 and 60 %. The 1st group included aged 40–54 patients, and the 2nd group included aged 57–74 patients. Results and conclusion. It was found that after 3 courses of the motor-cognitive training of dynamic type (“Lights”), conditionally “younger” patients showed an increase of their results from the fi rst to the third session in all four variants of the changing BFB depth (15, 30, 45, 60 %) from the normal sensitiveness of the force platform. These results weren’t found in dynamics in the 2nd group of patients. Data from static training (“Target”) shows that changing of the BFB depth in the range from 15 to 60 % don’t affect the results of exercises in both groups throughout 3 sessions. These types of training for older patients weren’t as effective as for younger patients over such a short period. Probably, these results of dynamic training depend on multitasking and learning difficulties. The obtained results should be taken into account when a training plan will be drowned up because the incorrect selection of the BFB depth and the short period of medical rehabilitation will reduce the eff ect of training.

1980 ◽  
Vol 95 (3) ◽  
pp. 289-297 ◽  
Author(s):  
J. G. M. Klijn ◽  
S. W. J. Lamberts ◽  
F. H. de Jong ◽  
K. J. van Dongen ◽  
J. C. Birkenhäger

Abstract. In 44 consecutive acromegalic patients we studied the interrelationships between tumour size, age, incidence of extrasellar extension, growth hormone levels and 'tumour growth'. These parameters were compared with results from a previous study in 62 prolactinoma patients. It appeared that the incidence of extrasellar extension in acromegalic patients was lower than in the prolactinoma patients (32 versus 44%). In acromegalic patients extrasellar extension occurred on the average at a lateral sellar and tumour area of almost 1 cm2 larger than in prolactinoma patients (with respect to sellar size generally above 3 cm2 versus 2 cm2, with respect to tumour size generally above 4 cm2 versus 3 cm2). Log tumour size and log basal growth hormone level were positively correlated (P < 0.0005). In the acromegalic patients there was a negative correlation between the size of the pituitary tumour and the age of the patient (P < 0.005) in contrast to the absence of such a relationship in the prolactinoma patients. In the group of acromegalic patients mean tumour size decreased gradually from the third to the sixth decade (5.0, 3.8, 3.0 and 2.3 cm2, respectively). The interval between the time of appearance of symptoms and the time of diagnosis was significantly shorter in younger patients and in women. The restriction of large tumours (lateral area > 5 cm2) to young patients (< 35 year) and the short period between the appearance of symptoms and the time of diagnosis in these patients indicate that growth hormone secreting pituitary tumours generally grow more rapidly in younger patients.


Author(s):  
O. V Kubryak ◽  
E. N Panova

The extensive application of various types of biological feedback mechanisms for the purpose of medical rehabilitation, e.g. as exemplified by «immersion» of the patient in the synthetic («virtual», «enhanced») environment, poses an important problem concerning the terminology, definitions, identification of the differences, and the selection of such artificial realities. In the current Nomenclature of medical services introduced into the clinical practice by the Order of the Ministry of Health of the Russian Federation (No 1664n dated 27.12.2011), the following codes can be attributed to the items concerning the possible use of virtual environments: A19.03.001.014 «Training with biological feedback from the support reaction in patients presenting with spinal injury» or A19.03.001.017 «Training with biofeedback via the kinesiology image of the manner of motion in the patients suffering from spinal injury», etc. At present, the use of the virtual environments and objects for the purpose of relaxation which are yet not coded as the medical services is extensively practiced at the treatment-and-prophylactic establishments of the spa and health resort type. This brief review is perhaps the first or one of the first attempts to explicitly define and represent the multidisciplinary approach to the problem being analyzed in the context of medical rehabilitation with the consistent information synthesis. The aim of the present work was to provide rehabilitation medicine professionals and other specialists with the information pertaining to the interpretation of the materials having a bearing on the main line of these studies.


PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257986
Author(s):  
Ana Carolina Dutra-Tavares ◽  
Alex C. Manhães ◽  
Keila A. Semeão ◽  
Julyana G. Maia ◽  
Luciana A. Couto ◽  
...  

The first symptoms of schizophrenia (SCHZ) are usually observed during adolescence, a developmental period during which first exposure to psychoactive drugs also occurs. These epidemiological findings point to adolescence as critical for nicotine addiction and SCHZ comorbidity, however it is not clear whether exposure to nicotine during this period has a detrimental impact on the development of SCHZ symptoms since there is a lack of studies that investigate the interactions between these conditions during this period of development. To elucidate the impact of a short course of nicotine exposure across the spectrum of SCHZ-like symptoms, we used a phencyclidine-induced adolescent mice model of SCHZ (2.5mg/Kg, s.c., daily, postnatal day (PN) 38-PN52; 10mg/Kg on PN53), combined with an established model of nicotine minipump infusions (24mg/Kg/day, PN37-44). Behavioral assessment began 4 days after the end of nicotine exposure (PN48) using the following tests: open field to assess the hyperlocomotion phenotype; novel object recognition, a declarative memory task; three-chamber sociability, to verify social interaction and prepulse inhibition, a measure of sensorimotor gating. Phencyclidine exposure evoked deficits in all analyzed behaviors. Nicotine history reduced the magnitude of phencyclidine-evoked hyperlocomotion and impeded the development of locomotor sensitization. It also mitigated the deficient sociability elicited by phencyclidine. In contrast, memory and sensorimotor gating deficits evoked by phencyclidine were neither improved nor worsened by nicotine history. In conclusion, our results show for the first time that nicotine history, restricted to a short period during adolescence, does not worsen SCHZ-like symptoms evoked by a phencyclidine-induced mice model.


2015 ◽  
Vol 6 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Courtney C Walton ◽  
Alexandra Kavanagh ◽  
Luke A. Downey ◽  
Justine Lomas ◽  
David A Camfield ◽  
...  

AbstractIt has been argued that cognitive training may be effective in improving cognitive performance in healthy older adults. However, inappropriate active control groups often hinder the validity of these claims. Additionally there are relatively few independent empirical studies on popular commercially available cognitive training programs. The current research extends on previous work to explore cognitive training employing a more robust control group. Twenty-eight healthy older adults (age: M = 64.18, SD = 6.9) completed either a multi-faceted online computerised cognitive training program or trained on a simple reaction time task for 20 minutes a day over a 28 day period. Both groups significantly improved performance in multiple measures of processing speed. Only the treatment group displayed improved performance for measures of memory accuracy. These results suggest improvements in processing speed and visual working memory may be obtained over a short period of computerized cognitive training. However, gains over this time appear only to show near transfer. The use of similar active control groups in future research are needed in order to better understand changes in cognition after cognitive training.


2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Mushahida Batool ◽  
Afsar Ali Bhatti ◽  
Maryam Gul ◽  
Ghulam Mustafa Arain ◽  
Abul Fadal Ali Khan

Introduction: Breast cancer is the commonest malignancy in women in the world. About 5% of all breast cancer patients are 35 years old or younger. Current literature suggests that breast cancer in these younger women may be different in etiology, clinical features and outcome from the disease seen in older women. Patients and methods: We included all breast cancer patients who underwent surgical treatment at Surgical Unit IV, Jinnah hospital, Lahore from December, 1998 to December, 2003. All patients who left against medical advice or were lost to follow up before completing treatment at our hospital wee excluded. The patients were divided into two groups by age. Those who were 35 years old or younger were placed in group 1 (88 patients) and those older than 35 years were placed in group 11(54 patients), which served as the control group. We compared the clinical presentation, the risk factor profile, and the grade and the stage of the tumor at presentation in younger women and their older controls. Results: The mean age in group I was 29.38 years 3.68 years. While the mean age in group II was 44.41 years 7.64 years. The commonest mode of presentation in both groups was a painless lump. (93.2% in group I and 66.67% in group II; p value < 0.001). The distribution of classical risk factors was similar in the two groups. These included family history (12.5% in group I and 11.1% in group II), nulliparity (7.95% in group I and 7.4% in group II), and oral contraceptives use(14.77% in group I and 12.96% in group II). Younger patients presented with a greater number of poorly differentiated (Grade III) tumors compared to the older patients. (73.76% vs.24.07%; p value <0.001). They also presented more frequently with hormone insensitive tumors (79.55% in group I vs. 24.52% in group II ; p value < 0.001). Mammography was positive more often in older women compared to the younger ones (97.44% vs.41.38% ; p value < 0.001). Ultrasound was done in 67.05% of the younger women and 27.78% in the older women. It was suggestive of malignancy in 89.83% of the younger women and 86.67% of the older ones. Modified radical mastectomy was done in 75% of the younger patients (Group I) and 61.11% of the older patients (Group II). Radical mastectomy was done in 19.32% of group I patients and 27.78% of group II patients. Older women underwent breast conservation treatment more often than the younger women (11.11% vs. 5.68%; p value < 0.05) Adjuvant chemotherapy was given more often to younger women (73.86% in group I vs. 9.26% in group II; p value < 0.0001). On the other hand, older patients received hormonal therapy more often that the younger ones (74.07% vs. 20.45%; p value < 0.001). Younger patients also received adjuvant radiotherapy more frequently than their older counterparts (84.32% vs. 49.26; p value <0.05). Conclusion: We conclude that women with breast cancer who are 35 years old or younger have more aggressive tumors than the older patients i.e. they present at a higher stage with poorly differentiated tumors that are frequently hormone insensitive.


2020 ◽  
pp. 4-11
Author(s):  
Marina Gerasimenko ◽  
Inna Evstigneeva ◽  
Aleksandr Kulikov ◽  
Olga Yarustovskaya ◽  
Tatyana Zaitseva

We conducted an objective and instrumental examination in 79 patients with radical mastectomy in the early postoperative period (2–4days), patients of the 1st group n=23 underwent 10procedures of postoperative suture fluctuation; patients of the 2nd group n=28 underwent 10procedures of fluctuating currents according to the extended technique; and patients of the 3rd group n=28 in addition to the extended technique underwent fluoridation of the forearm muscles by the same parameters. It has been proved that patients have reduced postoperative swelling, reduced pain, reduced the number of postoperative complications in the wound (inflammation, infectious processes, pain, suture divergence), shortened lymphorrhea. There is an increase in the amount and quality of movements, reduced sensitivity disorders in the upper limbs. Thus, the inclusion in the program of medical rehabilitation of various methods of appointment of fluctuating currents in the early postoperative period is appropriate and helps to reduce the time of recovery.


2021 ◽  
Vol 20 (2) ◽  
pp. 4-10
Author(s):  
Yuliya M. Getmanskaya ◽  
Iuly Treger

The COVID-19 pandemic has significantly affected all aspects of life around the world including both the medical system as a whole and individual medical specialties. Understandably, medical rehabilitation was forced to adapt to the new disease, to develop adequate algorithms and technologies that can increase the level of independence and quality of life being disrupted as a result of coronavirus infection. Aim. To analyze, organize and present the results of in-patient rehabilitation of patients after severe forms of COVID-19 infection by reporting the real cases from the clinical practice. Material and methods. COVID-19 infection is a multi-systemic disease, which, in many cases requires for inpatient multidisciplinary rehabilitation program. Patients after severe forms of infection suffer different symptoms in variable combinations. According to main disabling signs we can classify all our patients in 3 groups: (1) general weakness or deconditioning, (2) respiratory disorders due to lung disease, and (3) patients with different neurological complications. Patients in all groups demonstrate serious psychological compliances which indefinitely have negative influence on rehabilitation process. The paper presents clinical cases specific to each of the groups. Results. All hospitalized patients showed good functional improvement through quite standard length of stay in the department All patients were discharged home with the opportunity to return to relatively normal daily activities. Conclusions. Patients after severe COVID-19 infection require professional multidisciplinary in-patient rehabilitation. All of them demonstrate good functional improvement and, after quite short period of hospitalization, can be discharged home.


1962 ◽  
Vol 14 ◽  
pp. 133-148 ◽  
Author(s):  
Harold C. Urey

During the last 10 years, the writer has presented evidence indicating that the Moon was captured by the Earth and that the large collisions with its surface occurred within a surprisingly short period of time. These observations have been a continuous preoccupation during the past years and some explanation that seemed physically possible and reasonably probable has been sought.


1974 ◽  
Vol 22 ◽  
pp. 193-203
Author(s):  
L̆ubor Kresák

AbstractStructural effects of the resonance with the mean motion of Jupiter on the system of short-period comets are discussed. The distribution of mean motions, determined from sets of consecutive perihelion passages of all known periodic comets, reveals a number of gaps associated with low-order resonance; most pronounced are those corresponding to the simplest commensurabilities of 5/2, 2/1, 5/3, 3/2, 1/1 and 1/2. The formation of the gaps is explained by a compound effect of five possible types of behaviour of the comets set into an approximate resonance, ranging from quick passages through the gap to temporary librations avoiding closer approaches to Jupiter. In addition to the comets of almost asteroidal appearance, librating with small amplitudes around the lower resonance ratios (Marsden, 1970b), there is an interesting group of faint diffuse comets librating in characteristic periods of about 200 years, with large amplitudes of about±8% in μ and almost±180° in σ, around the 2/1 resonance gap. This transient type of motion appears to be nearly as frequent as a circulating motion with period of revolution of less than one half that of Jupiter. The temporary members of this group are characteristic not only by their appearance but also by rather peculiar discovery conditions.


1999 ◽  
Vol 173 ◽  
pp. 381-387
Author(s):  
M. Królikowska ◽  
G. Sitarski ◽  
S. Szutowicz

AbstractThe nongravitational motion of five “erratic” short-period comets is studied on the basis of published astrometric observations. We present the precession models which successfully link all the observed apparitions of the comets: 21P/Giacobini-Zinner, 31P/Schwassmann-Wachmann 2, 32P/Comas Solá, 37P/Forbes, and 43P/Wolf-Harrington. We used the Sekanina's forced precession model of the rotating cometary nucleus to include the nongravitational terms into equations of the comet's motion. Values of six basic parameters (four connected with the rotating comet nucleus and two describing the precession of spin-axis of the nucleus) have been determined along the orbital elements from positional observations of the comets. The solutions were derived with additional assumptions which introduce instantaneous changes of modulus of reactive force,Aand of maximum of cometary activity with respect to perihelion time. The present precession models impose some contraints on sizes and rotational periods of cometary nuclei. According to our solutions the nucleus of 21P/Giacobini-Zinner with oblateness along the spin-axis of about 0.32 (equatorial to polar radius of 1.46) is the most oblate among five investigated comets.


Sign in / Sign up

Export Citation Format

Share Document