Nationwide, 63.0% of companies consider insecurity and crime as a major problem that affects them. (INEGI, 2018). On 2018 in Guanajuato, 93.3% of companies considered it unsafe, with an increase of 38.3% over 2016 (INEGI, 2018). Their municipalities are no exception, in the case of Valle de Santiago, we seek to analyze the relationship between insecurity and violence with respect to annual sales of micro and small enterprises, the research is conducted through a cross-descriptive design, with a quantitative approach, through the questionnaire as an instrument, obtaining a sample of 550 companies. As a result of the research it was obtained that 90.7% of the directors of the micro and small companies express to be worried by the insecurity and violence that occurs in the municipality and therefore an impact is observed in the annual sales according to the calculation of the R square, obtaining 0.765. Given the importance that micro and small enterprises have for the economic development of the municipality, the issue of insecurity and violence must be considered a priority due to its growing incidence, not only at the local level.