scholarly journals Características clínicas do paciente com sorologia positiva para doença de chagas no ambulatório de cardiologia do hospital electro bonini / Clinical characteristics of patients with positive serology for chagas' disease at the cardiology outpatient clinic of electro bonini hospital

2021 ◽  
Vol 4 (6) ◽  
pp. 26669-26674
Author(s):  
Giovanna Magalhães Pacheco ◽  
Laís Macedo Menossi ◽  
Claudia Helena Cury Domingos ◽  
Reinaldo Bulgarelli Bestetti
Keyword(s):  
Chagas Disease ◽  
Outpatient Clinic ◽  
Clinical Characteristics ◽  
Positive Serology

scholarly journals Triatomine Fauna and Recent Epidemiological Dynamics of Chagas Disease in an Endemic Area of Northeast Brazil

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Cláudia M. Melo ◽  
Ana Carla F. G. Cruz ◽  
Antônio Fernando V. A. Lima ◽  
Luan R. Silva ◽  
Rubens R. Madi ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Disease Control ◽  
Chagas Disease ◽  
Control Program ◽  
The State ◽  
Positive Serology ◽  
Serological Tests ◽  
Systemic Analysis ◽  
South Central ◽  
Disease Control Program

Updated information of the dispersion dynamics of Chagas disease (CD) and a systemic analysis of these data will aid the early identification of areas that are vulnerable to transmission and enable efficient intervention. This work synthesized spatiotemporal information regarding triatomine fauna and analyzed this information in combination with the results from serological tests to elucidate the epidemiological panorama of CD in the state of Sergipe, Brazil. This is a retrospective analytical study that utilized information from the database of the National Chagas Disease Control Program. Between 2010 and 2016, 838 triatomines of eight species, namely, Panstrongylus geniculatus, which was first recorded in the state of Sergipe, Panstrongylus lutzi, P. megistus, Triatoma brasiliensis, T. pseudomaculata, T. tibiamaculata, T. melanocephala, and Rhodnius neglectus, were collected. Optical microscopy revealed that 13.2% of triatomines examined were infected by Trypanosoma cruzi-like flagellates. The distribution of triatomines exhibits an expanding south-central to northern dispersion, with a preference for semiarid and agreste areas and occasional observations in humid coastal areas due to anthropogenic actions reflected in the environment. Of the human cases analyzed from 2012 to 2016, 8.3% (191/2316) presented positive serology for Trypanosoma cruzi, and this proportion showed a gradual increase in the southern center of the state and new notifications in coastal regions. There is a need for intensification and continuity of the measures adopted by the Chagas Disease Control Program in Sergipe, identifying new priority areas for intervention and preferential ecotopes of the vectors, considering the occurrence of positive triatomines intradomicilliary and a source of new triatomines in the peridomiciles.

PT257 Positive Serology tendency for chagas disease in public hospital of Buenos Aires suburbs, in an 18 year period

Global Heart ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e216
Author(s):  
Monica Graciela Galli ◽  
Eduardo E. Alvarez ◽  
Marcelo V. Boscaro ◽  
Juan Seresi ◽  
Gustavo Marquez ◽  
...  
Keyword(s):  
Chagas Disease ◽  
Public Hospital ◽  
Buenos Aires ◽  
Positive Serology

scholarly journals Serological survey for Chagas' disease in school children in the Rio de Janeiro State, Brazil

1976 ◽  
Vol 10 (2) ◽  
pp. 85-89
Author(s):  
Walter B. Petana ◽  
José Rodrigues Coura ◽  
Henry P. F. Willcox
Keyword(s):  
Chagas Disease ◽  
School Children ◽  
Rio De Janeiro ◽  
Serological Survey ◽  
Positive Serology ◽  
Blood Samples ◽  
Number Of Children ◽  
Triatomine Bugs ◽  
Fluorescence Test ◽  
Janeiro State

A serological survey for Chagas' disease was carried out in school children in the Rio de Janeiro State, a zone considered as non-endemic for the infection. A total of 168 schools in 20 municipalities have been visited and 13,254 blood samples were obtained. The blood eluates were screened by the indirect fluorescence test (IFT), and all positive samples were checked and confirmed in sera by the complement fixation test (CFT). AH serologically positive children were subject to a clinical scrutiny, and the houses where the children lived have been searched for triatomine bugs. Only in two municipalities, Magé and Araruama, there was a significant number of children found positive. The total number of reactive samples by IFT and CFT from 13,004 blood samples screened was 143 (1.00 per cent). No serious clinicai symptoms suggestive of Chagas' disease have been found in any of the positive children, and no triatomine bugs were discovered in the dwellings where the children lived. The overall small percentage of children with positive serology postulates that the infection is not a serious health problem in the area investigated. It is recommended, however, to carry out a more detailed study in Magé and Araruama to find the reason for the relatively high percentage of serologically positive children encountered in these two municipalities.

scholarly journals Hyponatremia in Chagas disease heart failure: Prevalence, clinical characteristics, and prognostic importance

2015 ◽  
Vol 11 ◽  
pp. 6-9
Author(s):  
Reinaldo B. Bestetti ◽  
Augusto Cardinalli-Neto ◽  
Ana Paula Otaviano ◽  
Marcelo A. Nakazone ◽  
Natália D. Bertolino ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chagas Disease ◽  
Clinical Characteristics ◽  
Prognostic Importance

scholarly journals Characteristics of Individuals with Disagreement between Home and Ambulatory Blood Pressure Measurements for the Diagnosis of Hypertension

Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 457
Author(s):  
Chee Hae Kim ◽  
Je Sang Kim ◽  
Moo-Yong Rhee
Keyword(s):  
Blood Pressure ◽  
Serum Creatinine ◽  
Ambulatory Blood Pressure ◽  
Outpatient Clinic ◽  
Clinical Characteristics ◽  
Pressure Measurements ◽  
Cardiovascular Risks ◽  
The Mean ◽  
Ambulatory Blood Pressure Measurements ◽  
Diagnosis Of Hypertension

Home and ambulatory blood pressure (BP) measurements are recommended for the diagnosis of hypertension. However, the clinical characteristics of individuals showing a diagnostic disagreement between their home and ambulatory BP measurements are unclear. Of the 470 individuals who were not on antihypertensive drug treatment with a BP ≥140/90 mmHg at an outpatient clinic, 399 who had valid office, home, and ambulatory BP results were included. Hypertension was diagnosed based on an average home BP ≥135/85 mmHg and/or an average daytime ambulatory BP ≥135/85 mmHg. The participants were divided into three groups: Agree-NT (home and ambulatory BP normotension), Disagree (home BP normotension and ambulatory BP hypertension, or home BP normotension and ambulatory BP hypertension), and Agree-HT (home and ambulatory BP hypertension). Eighty-four individuals (21.1%) were classified as the Disagree group. The mean serum creatinine, triglycerides, and electrocardiogram voltage in the Disagree group were intermediate between those observed in the Agree-NT and the Agree-HT group. In the Disagree group, the mean levels of office and home diastolic BP, all of the components of ambulatory BP, the aortic systolic BP, and the BP variabilities were found to be intermediate between those of the Agree-NT and the Agree-HT groups. These results indicate that individuals showing a diagnostic disagreement between their home and ambulatory BP may have cardiovascular risks that are intermediate between those with sustained home and ambulatory normotension and hypertension.

scholarly journals The indeterminate form of human chronic Chagas' disease: a clinical epidemological review

1989 ◽  
Vol 22 (3) ◽  
pp. 147-156 ◽  
Author(s):  
João Carlos Pinto Dias
Keyword(s):  
Natural History ◽  
Trypanosoma Cruzi ◽  
Chagas Disease ◽  
Clinical Findings ◽  
X Rays ◽  
Classical Concept ◽  
Positive Serology ◽  
Indeterminate Form ◽  
History Of ◽  
Chronic Chagas Disease

Data on the epidemiology and the natural history of the indeterminate form of human chronic Chagas' disease (IFCCD) are discussed, revealing its great importance in endemic areas of Brazil. The work shows that IFCCD presents a gradual and very slow course, causing a benign picture in the studied patients. Evolution patterns, prognostic and anatomopathological features are also discussed. For practical purposes, the classical concept of IFCCD proved to be simple, operational and consistent, It is defined by the absence of symptoms and clinical findings in chronic infected patients with positive serology and/or parasitological examinations for Trypanosoma cruzi coupled with normal electrocardiographic and radiological exams (heart, oesophagus and colon X-Rays). If a patient is submitted to more rigorous and sophisticated tests, these can reveal some alterations, generally small ones and unable to interfere with the prognosis of the infection. It is suggested that research lines specially related to the evolution ary factors and immunological involvement during this phase be adopted.

Clinical characteristics and outcome of 107 adult patients with chronic Chagas disease and parasitological cure criteria

2013 ◽  
Vol 107 (6) ◽  
pp. 372-376 ◽  
Author(s):  
Graciela L. Bertocchi ◽  
Carlos A. Vigliano ◽  
Bruno G. Lococo ◽  
Marcos A. Petti ◽  
Rodolfo J. Viotti
Keyword(s):  
Chagas Disease ◽  
Clinical Characteristics ◽  
Adult Patients ◽  
Chronic Chagas Disease

scholarly journals Surgical treatment of relapsed megaesophagus

2020 ◽  
Vol 47 ◽  
Author(s):  
LUIGI CARLO DA SILVA COSTA ◽  
JOÃO GABRIEL ROMERO BRAGA ◽  
VALDIR TERCIOTI JUNIOR ◽  
JOÃO DE SOUZA COELHO NETO ◽  
JOSÉ ANTÔNIO POSSATTO FERRER ◽  
...  
Keyword(s):  
Weight Loss ◽  
Retrospective Study ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Chagas Disease ◽  
Surgical Procedures ◽  
Postoperative Period ◽  
Outpatient Clinic ◽  
Surgical Result ◽  
Stage 1

ABSTRACT Objective: to analyze the surgical treatment of patients with recurrent megaesophagus followed at the esophageal-stomach-duodenal outpatient clinic of the Hospital de Clínicas - UNICAMP. Methods: a retrospective study, from 2011 to 2017, with 26 patients with Chagas or idiopathic megaesophagus, surgically treated, and who recurred with dysphagia. Clinical, endoscopic and radiographic aspects were assessed and correlated with the performed surgical procedures. Results: 50% had dysphagia for liquids, 69% regurgitation, 65.3% heartburn, 69.2% weight loss and 69.2% had Chagas disease. In addition, 38.4% had megaesophagus stage 1 and 2 and 61.5% stage 3 and 4. Regarding the reoperations, 53% of them underwent Heller-Pinotti surgery by laparoscopy, Serra-Dória in 30.7% and esophageal mucosectomy in 7.9%. In 72% of the reoperations there were no postoperative complications, and 80% of the patients had a good outcome, with reduction or elimination of dysphagia. Among the reoperated patients undergoing the laparoscopic Heller-Pinotti technique, three reported little improvement of dysphagia in the postoperative period and among those who underwent Serra-Dória surgery, 100% had no dysphagia. It was observed that, when the time between the first procedure and the reoperation was longer, the better the surgical result was, with statistical significant decreased dysphagia (p=0.0013, p<0.05). Conclusions: there was a preference to perform laparoscopic re-miotomy and, as a second option, Serra-Dória surgery, for patients with recurrent megaesophagus. Esophagectomy or esophageal mucosectomy were reserved for more severe patients.

scholarly journals Association between the elevation of biomarkers and incipient alterations in ventricular function in patients with Chagas disease without evidence of specific organ damage

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Chirino ◽  
C Dizeo ◽  
V Volverg ◽  
G Toledo ◽  
V Vecchio ◽  
...  
Keyword(s):  
Diastolic Function ◽  
Ventricular Function ◽  
Chagas Disease ◽  
Myocardial Damage ◽  
Tissue Doppler ◽  
S Wave ◽  
Positive Serology ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Abstract Background Chagas disease (ChD) has a long asymptomatic period, where there is no evidence of myocardial damage. However, incipient alterations in ventricular systo-diastolic function have been described using echocardiography with Tissue Doppler and Strain. On the other hand, the presence of elevated higth-sensitivity T troponin (HS-TnT) and N-terminal pro B-type natriuretic peptide (NT-pro BNP) has been documented in the early stages of the ChD. The association between the elevation of both markers and incipient alterations in ventricular function in patients with ChD without evidence of heart damage has been poorly studied. Purpose The aim of this study is to evaluate the prevalence of elevation of both biomarkers (HS-TnT and NT-proBNP) and their association with insipients alterations in systo-diastolic function in patients with ChD without evidence of structural heart affection. Materials and methods Outpatients with stage 0 of ChD (positive serology, with normal electrocardiogram, holter and chest teleradiography) were included prospectively. They were divided in three groups according to the dosage of HS-TnT and NT-proBNP. Group 1: patients with both markers within normal values; group 2: patients with elevation of one of the markers (HS-TnT&gt;13 ng/L OR NT-proBNP&gt;125 pg/ml) and group 3: patients with elevation of both markers (HS-TnT&gt;13 ng/L AND NT-proBNP&gt;125 pg/ml). All of them underwent Doppler echocardiography with tissue Doppler. Results Two hundred and sixty-one patients were included, with 47±9 years old of age, 44% woman, 86.6% (n=226) in group 1, 9.6% (n=25) in group 2 and 3.8% (n=10) in group 3. Table 1 shows the main results. Conclusions Elevation of both markers was found in almost 4% of patients. This elevation was associated with a higher E/e' ratio, E/A ratio, Letf Atrial Area and a lower S'-wave lateral. Funding Acknowledgement Type of funding source: None

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