scholarly journals Metabolic Risk Factors and Associated Morbidities among Adult Urban People in Pyin Oo Lwin Township

2019 ◽  
Vol 31 (2) ◽  
pp. 105-110
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Age Distribution ◽  
Metabolic Risk Factors ◽  
P Value ◽  
Metabolic Risk ◽  
Cross Sectional ◽  
Total Prevalence ◽  
Significant Difference ◽  
Urban People

Metabolic syndrome is a cluster of risk factors for type 2 diabetes and cardiovascular disease, with insulin resistance proposed as a linking factor. It is common and is increasing in prevalence worldwide, largely attributed to increasing obesity and sedentary lifestyles, and now is both a public health and clinical problem. This community-based, cross-sectional descriptive study was conducted during 2015 to identify metabolic risk factors and associated morbidities among adult urban people in Pyin Oo Lwin Township. A total of 355 participants, 94 men (26.5%) and 261 women (73.5%) were enrolled. Age distribution was from 18 to 85 years with mean of 49.98 (SD:15.22) years. Metabolic risk factors were identified according to National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III) guideline. In this study, central obesity was the highest component with 145 subjects (40.8%) followed by elevated triglycerides 129(36. 3%), elevated blood pressure 104(29.3%), low HDL-cholesterols 85(23.9%), and elevated fasting glucose in only 48 individuals (13.5%). The total prevalence of metabolic syndrome was 35.2% with 26.6% in men and 38.3% in women, respectively. There were statistically significant associations above all five metabolic risk factors with metabolic syndrome (p value <0.001). Regarding its associated morbidities, ECG examinations showed normal 296 cases (83.4%) and abnormal in 59 cases (16.6%) but there was no significant difference between metabolic syndrome and abnormal ECG findings. In conclusion, this study recognizes the high prevalence rate of metabolic syndrome and can be depicted about the metabolic risks as the baseline data for implementation of further activities to reduce the incidence of non-communicable diseases.

scholarly journals Association between neck circumferences and cardiometabolic risk factors

2019 ◽  
Vol 6 (2) ◽  
pp. 318
Author(s):  
Mukhtarahmed Bendigeri ◽  
Ali Akbar ◽  
Dheeraj Kumar Reddy ◽  
Prakruthi Jaladhar
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Overweight And Obesity ◽  
Neck Circumference ◽  
Metabolic Risk Factors ◽  
P Value ◽  
Metabolic Risk ◽  
Anthropometric Measures ◽  
College Hospital

Background: Anthropometric measures have been used for screening patients for cardiovascular abnormalities and metabolic syndrome since many years. There are numerous methods to assessing overweight and obesity, such as measurements of weight, height, waist circumference, hip circumference and calculation of waist hip ratio and BMI. Due to cultural inhibitions measurement of hip, thigh or waist circumference is cumbersome in females, neck circumference could be an acceptable option for such patients.Methods: A cross-sectional study was conducted on patients attending the outpatient department in Yenepoya medical college Hospital between the period of May 2017 to May 2018. Total 201 patients chosen randomly in which 145 males and 56 females, fulfilling criteria of age >20 years were included. Pregnant females, patients with thyroid disorders, history of previous neck surgery were excluded.Results: Out of the 201 population studied, Cardio metabolic syndrome was present in 94 participants according to criteria of NCEP ATP III. In our study there is a significant correlation between neck circumference and metabolic syndrome (p value <0.001).Conclusions: Patients with Neck Circumference (NC) >37 cm in males and >34 cm in females are more prone for having cardio metabolic risk factors than patients with NC <37 cm in males and <34 cm in females. NC may be used as a simple and time saving screening measure to identify cardio metabolic risk factors in patients.

scholarly journals Trends in known and undiagnosed diabetes, HbA1c levels, cardio-metabolic risk factors and diabetes treatment target achievement in repeated cross-sectional surveys – The Tromsø Study 1994-2016

2020 ◽  
Author(s):  
Petja Lyn Langholz ◽  
Tom Wilsgaard ◽  
Inger Njølstad ◽  
Rolf Jorde ◽  
Laila Arnesdatter Hopstock
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Metabolic Risk Factors ◽  
Undiagnosed Diabetes ◽  
Metabolic Risk ◽  
Diabetes Treatment ◽  
Cross Sectional ◽  
Treatment Target ◽  
The Metabolic Syndrome ◽  
Hba1c Levels

AbstractObjectivesThe aim of this study was to investigate time trends in known and undiagnosed diabetes, HbA1c levels, and other cardio-metabolic risk factors in the general population as well as treatment target achievement among those with diabetes.Design and settingRepeated cross-sectional surveys in the population-based Tromsø Study.MethodsWe used age-adjusted generalized estimating equation models to study trends in self-reported and undiagnosed (HbA1c ≥6.5%) diabetes, cardio-metabolic risk factors and the metabolic syndrome in 27281 women and men aged 40-84 years examined in up to four surveys of the Tromsø Study between 1994 and 2016. Further, we analyzed trends in diabetes treatment target achievement.ResultsDuring 1994-2016 diabetes prevalence increased in women (2.3% to 3.9%) and men (2.4% to 5.3%) and in all age-groups, while the proportion of undiagnosed diabetes in women (33% to 20%) and men (37% to 27%) decreased. Blood pressure and total cholesterol decreased, while waist circumference increased in participants with and without diabetes, leading to a relatively stable prevalence of the metabolic syndrome throughout the study period. There was a marginal increase in HbA1c levels among participants without diabetes. Only half of those with diabetes achieved the treatment target of HbA1c ≤7.0%.ConclusionIn the last two decades diabetes prevalence increased, while the proportion of undiagnosed diabetes declined. The prevalence of the metabolic syndrome remained stable throughout, driven by opposing trends with an increase in obesity and a decrease in other cardio-metabolic risk factors. HbA1c treatment target achievement did not improve.

scholarly journals The Cut-Off Values of Anthropometric Indices for Identifying Subjects at Risk for Metabolic Syndrome in Iranian Elderly Men

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Mojgan Gharipour ◽  
Masoumeh Sadeghi ◽  
Minoo Dianatkhah ◽  
Shirin Bidmeshgi ◽  
Alireza Ahmadi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Area Under The Curve ◽  
Roc Curves ◽  
Metabolic Risk Factors ◽  
Youden Index ◽  
Elderly Subjects ◽  
Metabolic Risk ◽  
Anthropometric Indices ◽  
Cross Sectional

Aim. This study aimed to investigate which anthropometric indices could be a better predictor of metabolic syndrome (MetS) and the cut-off points for these surrogates to appropriately differentiate MetS in the Iranian elderly.Method. The present cross-sectional study was conducted on a sample of Isfahan Healthy Heart Program (IHHP). MetS was defined according to Third Adult Treatment Panel (ATPIII). In total, 206 elderly subjects with MetS criteria were selected. Anthropometric indices were measured and plotted using receiver operating characteristic (ROC) curves.Results. WC followed by WHtR yielded the highest area under the curve (AUC) (0.683; 95% CI 0.606–0.761 and 0.680; 95% CI 0.602–0.758, resp.) for MetS. WC at a cut of 94.5 cm resulted in the highest Youden index with sensitivity 64% and 68% specificity to predict the presence of ≥2 metabolic risk factors. BMI had the lowest sensitivity and specificity for MetS and MetS components. WC has the best ability to detect MetS which followed by WHtR and BMI had a lower discriminating value comparatively.Conclusion. WC is the best predictor for predicting the presence of ≥2 metabolic risk factors among Iranian elderly population and the best value of WC is 94.5 cm. This cut-off values of WC should be advocated and used in Iranian men until larger cross-sectional studies show different results.

scholarly journals The Prevalence of Metabolic Syndrome in Iranian Firefighters

2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Farzaneh Montazerifar ◽  
Mansour Karajibani ◽  
Razieh Hosseini ◽  
Aliyeh Tafazzoli ◽  
Ahmad Bolouri
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Work Experience ◽  
Healthy Lifestyle ◽  
Density Lipoprotein ◽  
Fire Department ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Cross Sectional

Background: Metabolic syndrome (MetS) is closely related to the risk of cardiovascular disease (CVD), particularly in stressful occupations. Firefighting is a hazardous profession and is associated with high metabolic risk. However, limited studies on firefighters are available. Objectives: This study aimed to determine the prevalence of MetS among firefighters in Zahedan city, Iran. Methods: This cross-sectional study was performed on 140 firefighters (age range, 16 - 55 years) employed at the fire department in Zahedan city, southeast Iran. Anthropometric characteristics and metabolic risk parameters, including blood pressure (BP), fasting blood sugar (FBS), and lipid profile were measured, and the prevalence of metabolic syndrome was assessed based on National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Results: MetS was presented in 47 (33.6%) of the firefighters. Among the metabolic risk factors, abdominal obesity (87.1%), low-high density lipoprotein (HDL-C) (62.1%), and hypertriglyceridemia (61.4%) were more prevalent. Moreover, a significant increasing trend was found with increasing age and work experience (both, P = 0.05). However, no significant differences were found for the remaining metabolic risk factors. Conclusions: The findings showed that about one-third of the firefighters had MetS. Age, abdominal obesity, and dyslipidemia were independent risk factors for MS in the firefighters. Thus, efforts should be undertaken to implement healthy lifestyle promotion programs for firefighters.

scholarly journals Eating behavior affects cardio-metabolic risk in high school teenagers in a developing country

2020 ◽  
Vol 29 (1) ◽  
pp. 71-81
Author(s):  
Rita Suhadi ◽  
Phebe Hendra ◽  
Dita Maria Virginia ◽  
Christianus Heru Setiawan
Keyword(s):  
Risk Factors ◽  
Heart Rate ◽  
Waist Circumference ◽  
Eating Behavior ◽  
Eating Behaviors ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Cross Sectional ◽  
Male Subjects ◽  
Female Subjects

BACKGROUND Modernization negatively changes lifestyle, characterized by excessive eating and reduced energy consumption, and concurrently increases the cardiometabolic risk. This study was aimed to evaluate the association between eating behavior and cardio-metabolic risk factors including body mass index (BMI) in percentile, blood pressure (BP) in percentile, waist circumference, and heart rate in total subjects and gender sub-groups. METHODS This analytical cross-sectional study was done from July to November 2018. High schools in four provinces of Indonesia and students were selected using purposive sampling. Subjects’ profiles were collected from interview and cardio-metabolic parameters were measured at the study sites. Data were analyzed with chi-square and independent t-test. RESULTS Subjects who were overweight/obese and had high BP accounted for 27.1% and 9.3–12.0% of the total subjects (n = 768), respectively. Subjects who having breakfast tended to have lower BMI (p = 0.006), and the lower consumption of western meals had lower heart rate (p = 0.02). Male subjects had more meal frequency and had less quantity of snacks than female subjects (p<0.001). Male subjects with routine intake of vegetables had low heart rate (p = 0.03). Female subjects with routine breakfast had better BMI (p<0.001), and lower diastolic BP (p = 0.004) and waist circumference (p = 0.02), whereas those who consumed Western meals had higher heart rate (p = 0.046) and waist circumference (p = 0.001). CONCLUSIONS Eating behaviors are likely to affect cardio-metabolic risk factors, and the effects vary within gender groups.

scholarly journals Vitamin D status and associated metabolic risk factors among North Korean refugees in South Korea: a cross-sectional study

BMJ Open ◽  
2015 ◽  
Vol 5 (11) ◽  
pp. e009140 ◽  
Author(s):  
Kyeong Jin Kim ◽  
Yoon Jung Kim ◽  
Sun Hwa Kim ◽  
Jee Hyun An ◽  
Hye Jin Yoo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
South Korea ◽  
Cross Sectional Study ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Cross Sectional ◽  
North Korean Refugees

Interleukin-6 G-174C gene polymorphism and serum resistin levels in North Indian women: Potential risk of metabolic syndrome

2010 ◽  
Vol 30 (10) ◽  
pp. 1445-1453 ◽  
Author(s):  
A Gupta ◽  
V Gupta ◽  
AK Singh ◽  
S Tiwari ◽  
S Agrawal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Genetic Polymorphism ◽  
Interleukin 6 ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Obese Women ◽  
Resistin Level ◽  
Indian Women ◽  
Mutant Genotype

The present investigations were aimed to identify the possible association between genetic polymorphism in interleukin-6 (IL-6) G-174C gene, which confers susceptibility to metabolic syndrome, and serum level of resistin in North Indian women. The study population comprised 370 unrelated Indian women (192 having abdominal obesity and 178 controls). Polymorphism in genotype (CC+GC) of IL-6 G-174C gene was determined using a combination of polymerase chain reaction (PCR) and sequence-specific primer with restriction fragment length polymorphism (RFLP) technology. Insulin resistance (IR) and serum resistin level were also analyzed along with metabolic risk factors. Of 192 abdominal obese women, 147 (76.56%) were found to have mutant CC+GC ( p = 0.001) genotype and allele frequency ( p = 0.001), which was significantly higher 45 (23.44%) than non-obese and their respective wild type. The mutant genotype (CC+GC) of IL-6 gene was found to be associated significantly with high triglyceride ( p = 0.025) and resistin level ( p < 0.001), when compared with respective wild genotype (GG) in obese women. Non-obese women with no signs of metabolic risk factors were found to have significantly low level of serum resistin and IR in comparison to obese women having genetic polymorphism for IL-6 G-174C gene. Study suggests that IL-6 G-174C gene is one among the susceptibility loci for metabolic syndrome in North Indian women. Genotype for this polymorphism may prove informative for prediction of genetic risk for metabolic syndrome. Further, high level of serum resistin molecules may be targeted to correlate with metabolic syndrome risk factors and could be used as early prediction marker.

scholarly journals The prevalence and risk factors of high-altitude pulmonary hypertension among native Tibetans in Sichuan Province, China

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
Q.L Gou ◽  
R.F Shi ◽  
X Zhang ◽  
Q.T Meng ◽  
X.R Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Pulmonary Hypertension ◽  
High Altitude ◽  
Multivariate Logistic Regression Analysis ◽  
Sichuan Province ◽  
Public Institution ◽  
P Value ◽  
Funding Source ◽  
Cross Sectional

Abstract Background High-altitude pulmonary hypertension (HAPH) remains a concern due to its high mortality, however, studies evaluating its prevalence and risk factors are lacking. Objective To determine the prevalence of HAPH and its correlated factors among the highlanders living at 3200 metres above sea level in Ganzi Tibetan Automous Prefecture, Sichuan Province, China. Methods This was a single-center cross-sectional study involved 1129 subjects (mean age 46.6±14 years, 39% men). Native Tibetans with HAPH were defined as mean pulmonary artery pressure &gt;30mmHg achieved from transthoracic echocardiography. Results The crude prevalence of HAPH was 6.2%, and was more prevalent in men compared to women (8.6% vs 4.6%, P=0.005). The elder was more likely to develop HAPH (OR: 5.308, 95% CI: 2.562–10.993). Highlanders with HAPH had more severe metabolic abnormalities (including elevated blood pressure, blood glucose, blood lipids, BMI, etc. P value&lt;0.05) and significantly increased hemoglobin level (P=0.001). On multivariate logistic regression analysis, independent risk factors for HAPH were metabolic syndrome (OR: 3.128, 95% CI: 1.110–8.818), age (&gt;60 years vs &lt;40 years) (OR: 2.924, 95% CI: 1.282–6.669), and decreased SpO2 (OR: 1.072 per 1-unit decrease; 95% CI: 1.010–1.136). Conclusion It could be concluded that HAPH was prevalent among 6.2% native Tibetans in Sichuan Province, China. Increasing age, metabolic syndrome and decreased SpO2 were independent predisposing factors for HAPH Funding Acknowledgement Type of funding source: Public Institution(s). Main funding source(s): This study was funded by one Science and Technology Pillar Programs in Sichuan Province (Grant no. 2017SZ0008).

scholarly journals Impact of age, body weight and metabolic risk factors on steroid reference intervals in men

2020 ◽  
Vol 182 (5) ◽  
pp. 459-471
Author(s):  
Marco Mezzullo ◽  
Guido Di Dalmazi ◽  
Alessia Fazzini ◽  
Margherita Baccini ◽  
Andrea Repaci ◽  
...  
Keyword(s):  
Risk Factors ◽  
Reference Intervals ◽  
Metabolic Risk Factors ◽  
Specific Reference ◽  
Metabolic Risk ◽  
Cross Sectional ◽  
Cholesterol Ratio ◽  
Age Related ◽  
Reference Limits ◽  
17 Hydroxyprogesterone

Objective To evaluate the independent impact of age, obesity and metabolic risk factors on 13 circulating steroid levels; to generate reference intervals for adult men. Design Cross-sectional study. Methods Three hundred and fifteen adults, drug-free and apparently healthy men underwent clinical and biochemical evaluation. Thirteen steroids were measured by LC-MS/MS and compared among men with increasing BMI. Moreover, the independent impact of age, BMI and metabolic parameters on steroid levels was estimated. Upper and lower reference limits were generated in steroid-specific reference sub-cohorts and compared with dysmetabolic sub-cohorts. Results We observed lower steroid precursors and testosterone and increase in estrone levels in men with higher BMI ranges. By multivariate analysis, 17-hydroxyprogesterone and dihydrotestosterone decreased with BMI, while cortisol decreased with waist circumference. Estrone increased with BMI and systolic blood pressure. Testosterone decreased with worsening insulin resistance. 17-hydroxypregnenolone and corticosterone decreased with increasing total/HDL-cholesterol ratio. Age-related reference intervals were estimated for 17-hydroxypregnenolone, DHEA, 17-hydroxyprogesterone, corticosterone, 11-deoxycortisol, cortisol and androstenedione, while age-independent reference intervals were estimated for progesterone, 11-deoxycorticosterone, testosterone, dihydrotestosterone, estrone and estradiol. Testosterone lower limit was 2.29 nmol/L lower (P = 0.007) in insulin resistant vs insulin sensitive men. Furthermore, the upper limits for dihydrotestosterone (−0.34 nmol/L, P = 0.045), cortisol (−87 nmol/L, P = 0.045–0.002) and corticosterone (−10.1 nmol/L, P = 0.048–0.016) were lower in overweight/obese, in abdominal obese and in dyslipidaemic subjects compared to reference sub-cohorts, respectively. Conclusions Obesity and mild unmedicated metabolic risk factors alter the circulating steroid profile and bias the estimation of reference limits for testosterone, dihydrotestosterone, cortisol and corticosterone. Applying age-dependent reference intervals is mandatory for steroid precursors and corticosteroids.

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