Analysis of Cancer Incidence in the Population of the Leningrad Region

Author(s):  
АА Kovshov ◽  
YuA Novikova ◽  
VN Fedorov ◽  
NA Tikhonova ◽  
OA Istorik

Introduction: Extensive measures are taken in the Russian Federation to reduce cancer incidence and mortality in the population but the proportion of incident cases in advanced stages is still large while correct registration of deaths and diseases remains a challenge. Our objectives were to study the incidence of malignant neoplasms in the Leningrad Region, to establish territories at risk, and to analyze carcinogenic risk factors associated with environmental conditions in these territories. Materials and methods: We used data of the Federal Statistical Observation Forms No. 7 “Information on Malignant Neoplasms”, No. 12 “Information on the Number of Diseases Registered in Patients Living in the Service Area of a Medical Organization”, No. 18 “Information on the Sanitary Condition of the Subject of the Russian Federation”, and information on the size of population by sex and age in the Leningrad Region and its districts for 2008–2018. We applied a direct method of standardizing incidence rates by age, analyzed the dynamics of incidence, and estimated statistical significance of differences in the incidence rates between the territories of comparison. Results: Cancer incidence in the Leningrad Region was lower than that in Russia. In 2008–2018, the highest rates were registered in the Kirishsky and Podporozhsky districts. In the Podporozhsky district, the standardized incidence rate in 2018 was 328.1 cases per 100,000 population or 1.79 times higher than the regional average, while the average rate for 2008–2018 exceeded the regional average by 1.36 times. The Kirishsky district ranked second by the incidence of malignant neoplasms in the Leningrad Region in 2018 (241.4 cases per 100,000 population or 1.32 times higher than the regional average), while the average rate for 2008–2018 exceeded the regional one by 1.47 times. Conclusions: Additional research is necessary to establish the causes of high cancer incidence rates in the Kirishsky and Podporozhsky districts of the Leningrad Region.

2018 ◽  
Vol 8 (6) ◽  
pp. 438-443
Author(s):  
E. S. Bobyleva ◽  
A. Yu. Gorbunov ◽  
O. I. Starodubtsevа ◽  
Ya. M. Vakhrushev

The Community-acquired Pneumonia (CAP) is an urgent problem of modern medicine owing to its high prevalence, gravity of a current, the increasing resistance of a microflora to antibacterial therapy, a large number of complications and a high lethality. Udmurt republic is one of leaders among the regions of Russian Federation on morbidity by diseases of the respiratory system, include CAP. It is therefore necessary to take analysis and prognosis incidence for the future improving quality administer. Research objective. The analysis of incidence and mortality from diseases of respiratory organs in the Udmurt Republic for 2009-2016. Materials and methods. The retrospective and prospection clinical-epidemiological research of prevalence and primary incidence of diseases of respiratory organs among the adult population of the Udmurt Republic living in 4 cities is conducted (Izhevsk, Sarapul, Glazov, Votkinsk) and 25 rural areas for the 8-summer period (2009-2016). The analysis is carried out on the basis of data of the state statistical registration and reporting documentation of Budgetary institution of health care of the Udmurt Republic «Republican medical information and analysis center of the Ministry of Health of the Udmurt Republic». Results of a research. The prevalence of diseases of respiratory organs in the Udmurt Republic was 49871,39±1,33 on 100 thousand population. The average growth rate was 2,3%, and the average rate o f a gain was — 0,25%. In comparison with data for the same period to the Russian Federation, average growth rate the average rate of a gain — 5,48% was 1,7%, and that demonstrates some decrease in incidence. In the analysis of structure of incidence of diseases of respiratory organs of the population of the Udmurt Republic it is established that she throughout the entire period of observation significantly hasn’t changed. At the same time annually, leading places are taken by pneumonia and the chronic obstructive pulmonary disease (COPD). Estimating the level of primary incidence of diseases of respiratory organs, it is noted that on UR the average growth rate is 105,42%, the average rate of a gain of 5,42%, in comparison across the Russian Federation average growth rate of 87,07%, and the average rate of a gain — 12,93%. Conclusion. Thus, to UR, as well as in general across the Russian Federation steadily high incidence of pneumonia is noted. At the same time the tendency to increase in incidence and this pathology mortality is noted. This circumstance demands further studying of a problem of pneumonia, including improvement of methods of medical correction.


2020 ◽  
pp. 59-62
Author(s):  
T. V. Klinyshkova

Introduction. Malignant neoplasms of the reproductive system dominate the structure of cancer incidence in women in the Russian Federation. In the structure of oncogynecological diseases, uterine body cancer (UBC) leads the way.The purpose of the study: to analyze the dynamics of UBC incidence in the Omsk region in comparison with data for the Russian Federation in 2002–2018 years to determine the priorities of cancer prevention.Results. There was a moderate tendency to increase the incidence of UBC in the region (Rg. = +1.8 %; p < 0.001) and for the Russian Federation (Rg. = +1.7 %; p < 0.001). The maximum percentage was among patients of 60–69 years old (32.3 %). There was a moderate trend in increasing UBC among women of 30–39 years old, and in the group of women of 35–39 years old there was a distinct trend in increasing the incidence (Rg. = +5.6 %; p < 0.050). The article presents the epidemiological features of UBC in comparison with cervical cancer in the region: the increase in the incidence of UBC (Rg. =+1.8 %) and the stability of the indicator at cervical cancer (Rg. = +0.050 %), the trend to rejuvenate both locations of cancer.Conclusion. In Omsk Region, there is a unidirectional increase in the incidence of UBC with the Russian Federation, a trend in rejuvenating the disease, which dictates the need for cancer prevention in the practice of an obstetrician-gynecologist.


Dermatology ◽  
2020 ◽  
pp. 1-9
Author(s):  
Anastasiya Muntyanu ◽  
Feras M. Ghazawi ◽  
Hacene Nedjar ◽  
Elham Rahme ◽  
Akram Alakel ◽  
...  

<b><i>Background:</i></b> Non-melanoma skin cancer (NMSC) incidence has been increasing steadily around the world. The aim of the study is to describe geographic trends in incidence and mortality of NMSC in Russia between 2007 and 2017 and compare findings to other European countries. <b><i>Methods:</i></b> We used geospatial analysis to map the incident cases and descriptive statistical analysis to analyze trends. Additionally, we assessed the relationship between ethnicity, geographic latitude/longitude, and NMSC incidence/mortality rates. We retrospectively analyzed the data from the Moscow Oncology Research Institute, Ministry of Health of the Russian Federation, for 2007–2017. Routine methods of descriptive epidemiology were used to study incidence and mortality rates by age groups, years, and jurisdictions (i.e., Federal Districts and Federal Subjects). <b><i>Results:</i></b> In total, 733,723 patients were diagnosed with NMSC in Russia over the period 2007–2017, of whom 63% were women. The overall age-standardized incidence and mortality rates were 29.64/100,000 and 0.70/100,000, respectively. There was a consistent increase in age-standardized incidence rates over the study period, with a decreasing mortality rate. Geographic mapping revealed north-to-south and east-to-west gradients for NMSC. <b><i>Conclusions:</i></b> This study demonstrated longitudinal trends for NMSC incidence in Russia documenting that skin phototype, latitude/longitude, climate zones, and cultural practices remain dominant risk factors defining the epidemiology of NMSC. Moreover, this work identified several regions in the country (i.e., Republic of Adygea, Samara, Krasnodar Krai, etc.), where patient education/sun awareness campaigns will be useful to help reduce the risk of this malignancy.


2019 ◽  
Vol 22 (2) ◽  
pp. 99-107 ◽  
Author(s):  
Axel Skytthe ◽  
Jennifer R. Harris ◽  
Kamila Czene ◽  
Lorelei Mucci ◽  
Hans-Olov Adami ◽  
...  

AbstractThe Nordic countries have comprehensive, population-based health and medical registries linkable on individually unique personal identity codes, enabling complete long-term follow-up. The aims of this study were to describe the NorTwinCan cohort established in 2010 and assess whether the cancer mortality and incidence rates among Nordic twins are similar to those in the general population. We analyzed approximately 260,000 same-sexed twins in the nationwide twin registers in Denmark, Finland, Norway and Sweden. Cancer incidence was determined using follow-up through the national cancer registries. We estimated standardized incidence (SIR) and mortality (SMR) ratios with 95% confidence intervals (CI) across country, age, period, follow-up time, sex and zygosity. More than 30,000 malignant neoplasms have occurred among the twins through 2010. Mortality rates among twins were slightly lower than in the general population (SMR 0.96; CI 95% [0.95, 0.97]), but this depends on information about zygosity. Twins have slightly lower cancer incidence rates than the general population, with SIRs of 0.97 (95% CI [0.96, 0.99]) in men and 0.96 (95% CI [0.94, 0.97]) in women. Testicular cancer occurs more often among male twins than singletons (SIR 1.15; 95% CI [1.02, 1.30]), while cancers of the kidney (SIR 0.82; 95% CI [0.76, 0.89]), lung (SIR 0.89; 95% CI [0.85, 0.92]) and colon (SIR 0.90; 95% CI [0.87, 0.94]) occur less often in twins than in the background population. Our findings indicate that the risk of cancer among twins is so similar to the general population that cancer risk factors and estimates of heritability derived from the Nordic twin registers are generalizable to the background populations.


2016 ◽  
Vol 21 (6) ◽  
pp. 319-324
Author(s):  
Marina A. Shurgaya

The article is devoted to the problem of primary retirement due to malignant neoplasms in the adult population in the Russian Federation. There are presented results of a study of the dynamics (2005-2014) of the age-gender structure, level and severity of primary disability due to this socially significant disease. The ranking of subjects of the Russian Federation according to the intensive index, describing the prevalence of primary disability due to malignant neoplasms is presented also. Over the ten-year period the maximum number for the first time recognized as disabled (FTRD) was revealed to be observed in 2005, amounting to 200.4 thousand people, with a subsequent decrease to 170.2 thousand people in 2008. However, later the trend in the dynamics changed to the increase in the total number of FTRD due to malignant neoplasms and the gain in the index accountedfor 13% in comparison with 2008. In the age pattern of disability due to malignant neoplasms there are dominated elderly invalids (60.3 %), among which there are prevailed the invalids of the group I (31.2%) and group II (53.6%). The area with the lowest level of the primary disability due to malignant neoplasms among the population of elderly is the Sakhalin region (15.4 per 10 thousand of the elderly population). The greatest prevalence of malignant neoplasms occurs in the Kurgan region (52.3 at the average rate of 34.4 per 10 thousand of the elderly population). Also the unfavorable situation in the Kaluga region, the Republic of Kalmykia, Novosibirsk, Bryansk, Orenburg and Arkhangelsk regions (46.9-45.1) per 10 thousand of the elderly population), which requires measures for the effective prevention of primary disability due to this socially significant severe disabling pathology.


Author(s):  
E. V. Kovalevskiy ◽  
S. V. Kashanskiy ◽  
I. M. Tskhomariia

One of the malignant neoplasms, which is associated with exposure to only one factor - asbestos fibers, is malignant mesothelioma. At the same time, today there is already convincing evidence of its polyetiology. This indicates the urgent need to expand research in this direction in order to develop targeted preventive measures.


Author(s):  
J. Schüz ◽  
A. Olsson

Cancer is increasing worldwide. Th e Russian Federation is no exception in this regard with an increase of the total number of new cases predicted to rise from 529,062 in 2018 to 587,622 in 2040. Th e present high burden and increase in incident cases at the same time increases the pressure on healthcare infrastructure and related costs. Th us, primary and secondary prevention of cancer becomes essential. Occupational cancers related to exposure at the workplace are among the preventable cancer burden, due to the modifi ability of the risk through minimisation of occupational exposures and adequate worker protection. For the Russian Federation, some 20,000 cancers each year may be att ributable to occupation, but systematic recording is currently lacking. As information is also lacking on the absolute eff ect of various occupational carcinogens in the Russian workforce due to lack of large-scale epidemiological studies and because for many suspected occupational carcinogens the evidence may become stronger, the true burden may in fact be higher. Th e Russian Federation appears particularly suitable for research into occupational cancer given the sizable workforce, the heavy industr ialisation as well as the good documentation and workplace surveillance over time, so that results are both informative for the situation in the Russian Federation and on a global scale. Five challenging but not unfeasible steps of nationwide population-based cancer registration, development of a legal framework for record linkage of registries and data collections, recording of occupational cancers, large scale epidemiological occupational cancer research and rigorous implementation of worker protection on known carcinogens, lead the way to a continuously updated cancer control plan that includes the elimination of occupational cancer in the Russian Federation.


Author(s):  
Elizaveta Pavlik ◽  
Elena Ketenchieva

This article provides a classification and characteristics of persons convicted for crimes in the field of narcotic drugs and psychotropic substances illicit trafficking. The article deals with the statistics in this sphere over the past five years. Based on the collected empirical evidence the authors analyzed the qualitative indicators of convicted drug offenders. The examination of statistical data from investigative and judicial practice on crimes in the field of narcotic drugs and psychotropic substances illicit trafficking made it possible to sketch a criminal profile of a person sentenced to imprisonment: a citizen of the Russian Federation, a male between 18 to 39 years, having a secondary general or vocational education. Moreover, the personality of a convicted person is characterized by his internal criteria deformation devaluing the norms and rules that express and consolidate public interests. The authors also conducted a comparative analysis of offenders convicted both in the Russian Federation and in such federal subjects as Saint-Petersburg and Leningrad region. The choice of St. Petersburg as one of the objects of this research is justified by the fact that it has been among the leaders of the regions with the largest number of recorded drug-related crimes for several years.


Author(s):  
Stephanie C Melkonian ◽  
Hannah K Weir ◽  
Melissa A Jim ◽  
Bailey Preikschat ◽  
Donald Haverkamp ◽  
...  

Abstract Cancer incidence varies among American Indian and Alaska Native (AI/AN) populations, as well as between AI/AN and White populations. This study examined trends for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations and estimated potentially avoidable incident cases among AI/AN populations. Incident cases diagnosed during 2012–2016 were identified from population-based cancer registries and linked with the Indian Health Service patient registration databases to improve racial classification of AI/AN populations. Age-adjusted rates (per 100,000) and trends were calculated for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations (rate ratio &gt;1.0), by region. Trends were estimated using joinpoint regression analyses. Expected cancers were estimated by applying age-specific cancer incidence rates among non-Hispanic White populations to population estimates for AI/AN populations. Excess cancer cases among AI/AN populations were defined as observed minus expected cases. Liver, stomach, kidney, lung, colorectal and female breast cancers had higher incidence rate among AI/AN populations across most regions. Between 2012 and 2016, nearly 5,200 excess cancers were diagnosed among AI/AN populations, with the largest number of excess cancers (1,925) occurring in the Southern Plains region. Culturally informed efforts may reduce cancer disparities associated with these and other cancers among AI/AN populations.


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