scholarly journals KADAR HEMOGLOBIN DAN UJI TOURNIQUET PADA PASIEN ANAK DENGAN INFEKSI VIRUS DENGUE DI MANADO

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Joseph Hardi ◽  
Glady Rambert ◽  
Firginia Manoppo

Abstract: Dengue infection is a systemic and dynamic disease that has a broad spectrum. The key for good management and results is to know and understand arising signs. Various examination is necessary for diagnosis, one of them are the examination of hemoglobin levels and tourniquet test. This research was a cross sectional study. Samples were obtained from 37 pediatric patients with dengue virus infection of the total population sample of 72 patients in RS Advent Manado, RSU GMIM Pancaran Kasih Manado, and RSAD Robert Wolter Mongisidi Teling. The results of this study show the hemoglobin levels on pediatric patients with dengue virus infection mostly in normal levels and not all patients show positive tourniquet test results.Keywords: dengue, hemoglobin levels, tourniquet testAbstrak: Infeksi dengue adalah suatu penyakit sistemik dan dinamik yang memiliki spektrum yang luas. Kunci keberhasilan dalam pengelolaan dan hasil yang baik adalah mengenal dan memahami tanda-tanda yang timbul. Diperlukan berbagai pemeriksaan penunjang salah satu diantaranya adalah pemeriksaan kadar hemoglobin dan uji tourniquet. Penelitian ini merupakan penelitian cross sectional. Sampel penelitian diperoleh 37 pasien anak dengan infeksi virus dengue dari total populasi sampel 72 pasien di RS Advent Manado, RSU GMIM Pancaran Kasih Manado, dan RSAD Robert Wolter Mongisidi Teling. Hasil penelitian menunjukkan gambaran hemoglobin pada pasien anak dengan infeksi virus dengue sebagian besar dalam kadar normal dan tidak semua menunjukkan uji tourniquet positif.Kata kunci: dengue, kadar hemoglobin, uji tourniquet

2013 ◽  
Vol 1 (4) ◽  
pp. 224-227 ◽  
Author(s):  
B P Gupta ◽  
S K Mishra ◽  
K D Manandhar ◽  
R Malla ◽  
C S Tamarakar ◽  
...  

Dengue Virus infection is an emerging mosquito-borne disease. It is a global health problem and its expanding endemicity towards new territories is a serious concern. Relatively a new disease in Nepalese context, dengue abruptly appeared as massive outbreak in 2010, merely four years after its first introduction. It is a nagging public health problem in the low lands of Terai, expanding to new areas of Nepal in recent years.  A cross-sectional study was conducted to determine anti-Dengue IgM positive rate in Lumbini, Dhading and Chitwan district. The study was carried from June 2012 to November 2012. The total number of Serum samples was collected from 275 patients visiting hospitals with history of fever, headache and suspected DF. The samples were examined by ELISA. The anti-Dengue IgM positivity was found to be 29.09 %. The positive rate was highest in Dhading (70.37%) followed by Bharatpur (37.6%) and Lumbini (11.38%). The Dengue positive cases were higher in males (32.5 %) than female (24.8 %). The highest positive cases (41.6%) were from age group less than 15 years. Dengue has substantial expansion in Western and Far Western Terai region of Nepal which was limited to the middle Terai region in the past and mostly infects older people.DOI: http://dx.doi.org/10.3126/ijasbt.v1i4.9135  Int J Appl Sci Biotechnol, Vol. 1(4): 224-227


2017 ◽  
Vol 12 (3) ◽  
pp. 187
Author(s):  
Bashir Abdrhman Bashir Mohamed

Background Deranged liver is a well-recognized feature of dengue infection, often demonstrated by coagulopathy and mild to moderate increase in transaminase levels although jaundice and fulminant hepatic failure are generally uncommon. Objective This study aimed to evaluate the hepatic effect of dengue fever amongst Sudanese patients.Materials and Methods A cross-sectional descriptive study recruited in Port Sudan teaching hospital in the period from February 2013 to June 2014.  334 cases of dengue along with 101 cases of control were enrolled. Rapid immune chromatographic test was used to confirm positive dengue cases and WHO criteria were used for classifying the dengue severity. Prothrombin time (PT), partial thromboplastin time (PTT), fibrinogen level (FB), platelet count (PLT), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and C-reactive protein (CRP) were all measured. Results PT, PTT, and FB were found to be significantly higher in the infected cohort when compared to the controls (P< 0.0001). PT was prolonged in 9%, PTT was prolonged in 12.6% and shortened by 5.4% of the patients, whereas hypofibrinogenemia in 18.3% and hyperfibrinogenemia in 67.4% of the patients. Bleeding was seen in 10.5% of patients and thrombocytopenia was detected in 83.5% of patients. Out of 334 patients, 101 (30.2%) had abnormal coagulation results. Of 101 patients, 72 were subjected mixing studies for PT and PTT that revealed deficiencies in factors VIII (35%), IX (10%), V (10%), X (19%), and XII (14%). 43.6% patients had elevated AST and 21.8% had elevated ALT.ConclusionThis study demonstrated that hepatic dysfunction may be attributed to dengue virus infection which evident by prolongation in PT and PTT as well as hypofibrinogenemia and factor deficiencies.    


2021 ◽  
Vol 1 (2) ◽  
pp. 040-049
Author(s):  
Ezea Moses Chukwuemeka ◽  
Chukwuma Okechukwu George ◽  
Igwe Joy Ogugua ◽  
Abone Harrison Odera ◽  
Moses Ikechukwu Benjamin ◽  
...  

This study was designed to investigate the seroprevalence and impact of Haematological and biochemical markers of dengue virus infection among subjects co-infected with hepatitis B virus infection in Enugu State, Nigeria. The study involved a cross-sectional study consisting of 150 subjects (120 discordant and concordant partners of hepatitis B, and 30 controls). Dengue Virus IgM and IgG were analyzed using ELISA rapid kit while HBsAg was screened using a rapid ELISA diagnostic strip. Both Dengue and HBsAg were re-screened later to reaffirm the result using Ichroma Fluorescence Immunoassay (FIA). Haematological parameters were analyzed using Mindray autoanalyser while ALT/AST was analyzed using COBASS 111. Statistical analysis was performed using Graph Pad Prism. The results showed a prevalence of 44.7% dengue virus seropositivity among the study population, 43.3% in dengue/hepatitis B co-infected subjects. The dengue virus seropositive participants had significantly greater IgG (70.1%) levels compared to IgM (29.9%), more in females (68.6%) compared to males (31.4%), and predominantly in the age group 31 to 40 years. A significant higher (p<0.005) mean haemoglobin was seen in males compared to females, and there is no significant difference in both WBC and platelets. A greater mean of ALT (p=0.005), AST (p=0.018) is gotten in Dengue/HBV co-infection when compared to non- Dengue/HBV co-infected subjects. This study revealed a high seroprevalence of dengue virus infection and the possibility of hepatic complications. This calls for urgent medical attention and more studies to confirm the circulating strains of the dengue virus as well as its involvement in hepatic complications.


2019 ◽  
Vol 2 (1) ◽  
pp. 36
Author(s):  
Winni Aprillia Putri ◽  
Abu Rohiman ◽  
Sulistiawati Sulistiawati ◽  
Dwiyanti Puspitasari

Introduction: Dengue Virus Infection (DVI) is one of cautious mosquito-borne virus disease that transmitted by Aedes aegypti and Aedes albopictus. Surabaya has the highest incidence rate of DVI in East Java. Transmission of dengue virus were significantly affected by the change of climatic factor components (precipitation, temperature, and humidity). This study is aimed to analyze the correlation between climatic factor components with the incidence rate of DVI in Surabaya and its distribution.Methods: This is a cross-sectional study using analytic observational approach. The Incidence rate of DVI during 2010-2013 datas were taken from Surabaya Health Office. Climatic factor datas on the same years were taken from Juanda Meteorological Station. Correlation tests were performed by using Spearman Test.Results: As the result, there were 7,685 DVI patients during 2010-2013. Male patients have less proportion (51.89%). The highest DVI cases are from the age group of 5-14 years (>40%). Incidence rate of DVI was increased during February to April, and highest incidence rate occured in 2010 (n=3,379). There were significant correlation between precipitation (r=0.419, p-value p=0.003) and humidity (r=0.502, p-value=0.000) with the incidence rate of DVI in Surabaya during 2010-2013.Conclusion: Therefore, precipitation and humidity are two climatic factor components that may effect the incidence rate of DVI in Surabaya.


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