scholarly journals PERUBAHAN KADAR GULA DARAH POST MORTEM

e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Yuliana T. Sraun

Abstract: Normal blood glucose of human being is 70-110 mg/dl. After death, the process of glucose metabolism ceases, which affects the blood glucose level. This study aimed to obtain the changes of blood glucose levels after death. This was an observational study with a cross sectional design. Samples were post mortem patients with external examination at Prof. Dr. R.D. Kandou Hospital with the agreements of their families. Blood glucose levels post mortem were examined and data of blood glucose levels ante mortem were obtained from the medical record. Data were statitistically analyzed by using the bivariate test to find out the correlation between blood glucose levels ante mortem and post mortem. There were 14 patients post mortem as samples. The statistical analysis showed at the first hour post morem r = .042; the second hour r = - .103; and the third hour r = - .086 . Most of the patients showed decreases of blood glucose levels post mortem. However, some of them showed increases of blood glucose levels at the first hour post mortem. Conclusion: There was a significant relationship between the blood glucose levels ante mortem and post mortem.Keywords: blood glucose level, post mortem.Abstrak: Kadar gula darah normal pada manusia hidup berkisar antara 70 – 110 mg/dl. Setelah kematian, proses masuknya glukosa ke dalam sel dengan bantuan insulin kemungkinan tidak terjadi lagi karena aktivitas sel-sel dan jaringan akan terhenti sama sekali yang dapat mengakibatkan perubahan kadar gula darah post mortem. Penelitian ini bertujuan untuk mengetahui perubahan kadargula darah sewaktu (GDS) setelah kematian. Desain penelitian yang digunakan ialah cross sectional dengan metode observasional. Penelitian dilakukan pada pasien post mortem yang menjalani pemeriksaan luar di RSUP. Prof. Dr. R.D. Kandou dengan persetujuan keluarga. Kadar GDS post mortem dibandingkan dengan data GDS ante mortem, selanjutnya dilakukan uji bivariat untuk melihat hubungan GDS ante dan post mortem. Hasil uji satistik memperlihatkan pada jam pertama r = ,042, jam kedua r = -,103, dan jam ketiga r = -,086. Walaupun sebagian besar pasien memperlihatkan penurunan kadar GDS post mortem, namun terdapat juga beberapa pasien yang mengalami peningkatan GDS pada jam pertama awal kematian. Simpulan: Terdapat hubungan bermakna antara GDS ante dan post mortem.Kata kunci: GDS, post mortem.

2017 ◽  
Vol 1 (1) ◽  
pp. 33
Author(s):  
Etiek Nurhayati ◽  
Suwono Suwono ◽  
Everiandi Nur Fiki

Abstract: NaF or Sodium Fluoride are anticoagulants which often used for sampling tests of blood glucose levels because NaF is considered to inhibit the process of glycolysis. The purpose of this study was to determine the difference of blood glucose level that delayed for 2 hours using NaF anticoagulant and without using NaF anticoagulant at students of Medical Laboratory Pontianak. This research method was in the form of Cross-Sectional research. Sampling technique by random sampling with 39 people in total. Glucose examination method used was a method of glucose oxidase using blood serum. The result was the average value of blood glucose level using anticoagulant NaF was 80,256 mg/dl. While the average of blood glucose levels without the use of NaF anticoagulants was 73,589 mg/dl. The data obtained were analyzed statistically using paired t-test result (p = 0,001 <a 0,05). It can be concluded that there was a difference of blood glucose level when using NaF anticoagulant and without using NaF anticoagulant on students of Medical Laboratory Pontianak.Abstrak: Antikoagulan NaF atau Natrium Flourida adalah antikoagulan yang sering digunakan untuk sampling bahan pemeriksaan kadar glukosa darah, karena NaF dianggap mampu menghambat proses glikolisis. Tujuan penelitian ini untuk mengetahui perbedaan kadar glukosa darah sewaktu yang ditunda selama 2 jam menggunakan antikoagulan NaF dan tanpa menggunakan antikoagulan NaF pada mahasiswa/I Analis Kesehatan Pontianak. Desain penelitian menggunakana Cross Sectional. Teknik pengambilan sampel dengan cara simple random sampling dengan jumlah 39 orang. Metode pemeriksaan glukosa yang digunakan adalah metode glucose oxidase menggunakan sthe erum darah Hasil penelitian adalah rata–rata nilai kadar glukosa darah yang menggunakan antikoagulan NaF adalah 80,256 mg/dl. Sedangkan rata-rata kadar glukosa darah yang tanpa menggunakan antikoagulan NaF adalah 73,589 mg/dl. Data yang diperoleh dianalisis statistik menggunakan uji t-berpasangan didapatkan hasil (p = 0,001<a 0,05). Dapat disimpulkan terdapat perbedaan kadar glukosa darah sewaktu menggunakan antikoagulan NaF dan tanpa menggunakan antikoagulan NaF pada mahasiswa /i Analis Kesehatan Pontianak. 


2019 ◽  
Vol 1 (2) ◽  
pp. 41-45
Author(s):  
Suratno Suratno ◽  
Novidha Muji Rahayuningrum ◽  
Helmus Helmus

Alcohol consumption is often associated with the incidence of diabetes mellitus. This study aimed to examine fasting blood glucose levels and alcohol consumption in men in Mendawai, Palangka Raya, Central Kalimantan. The cross-sectional study design was carried out to asses fasting blood glucose levels on 20 male alcohol drinkers. Blood glucose assay was determined by an automated enzymatic colorimetric technique using Photometers (5010 V5+ Robert Riele). Determination of fasting blood glucose level using glucose oxidase and peroxidase (GOD-POD) method. This study found that 40% of alcohol drinker considered high fasting blood glucose level with an average level of 139.6 mg/dL. Twenty-five percent of alcohol drinkers regarded as low fasting blood glucose level with an average of 68.8 mg/dL. And 35% of drinkers have a normal level of fasting blood glucose with an average of 97.4 mg/dL


Trials ◽  
2022 ◽  
Vol 23 (1) ◽  
Author(s):  
Tao Yuan ◽  
Hongyu He ◽  
Yuepeng Liu ◽  
Jianwei Wang ◽  
Xin Kang ◽  
...  

Abstract Background Blood glucose levels that are too high or too low after traumatic brain injury (TBI) negatively affect patient prognosis. This study aimed to demonstrate the relationship between blood glucose levels and the Glasgow Outcome Score (GOS) in TBI patients. Methods This study was based on a randomized, dual-center, open-label clinical trial. A total of 208 patients who participated in the randomized controlled trial were followed up for 5 years. Information on the disease, laboratory examination, insulin therapy, and surgery for patients with TBI was collected as candidate variables according to clinical importance. Additionally, data on 5-year and 6-month GOS were collected as primary and secondary outcomes, respectively. For multivariate analysis, a generalized additive model (GAM) was used to investigate relationships between blood glucose levels and GOS. The results are presented as odds ratios (ORs) with 95% confidence intervals (95% CIs). We further applied a two- piecewise linear regression model to examine the threshold effect of blood glucose level and GOS. Results A total of 182 patients were included in the final analysis. Multivariate GAM analysis revealed that a bell-shaped relationship existed between average blood glucose level and 5-year GOS score or 6-month GOS score. The inflection points of the average blood glucose level were 8.81 (95% CI: 7.43–9.48) mmol/L considering 5-year GOS as the outcome and were 8.88 (95% CI 7.43−9.74) mmol/L considering 6-month GOS score as the outcome. The same analysis revealed that there was also a bell relationship between average blood glucose levels and the favorable outcome group (GOS score ≥ 4) at 5 years or 6 months. Conclusion In a population of patients with traumatic brain injury, blood glucose levels were associated with the GOS. There was also a threshold effect between blood glucose levels and the GOS. A blood glucose level that is either too high or too low conveys a poor prognosis. Trial registration ClinicalTrials.gov NCT02161055. Registered on 11 June 2014.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mrs. Vanitha. S s ◽  
Dr. Pramjit kaur

Challenges in lifestyle, such as increasesin energy intake and decreasesin physical activity are causing overweight and obesity leading to epidemic increases in type II Diabetes Mellitus. The research approach used for this study was evaluative approach and the research design was true experimental design. 60 patients with type II diabetes, 30 in experimental group and 30 in control group were selected for this study by using purposive sampling technique. Data was collected with the help of self-structured interview schedule. Descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (chi-square, paired ‘t’ test) were used to analyse the data and to test the hypotheses. In the experimental group,the pre-test mean score was 2.966, mean percentage was 59% and standard deviation was 1.129 and in post-testmean score was 2.533, mean percentage was 50.66% and standard deviation was 1.074 with effectiveness of 8.34% and paired‘t’ test value of t=3.971,which was statistically significant (p<0.05) which is an evidence ofthe effectiveness of Amla juice in reducing blood glucose level. Comparison of blood glucose levels in experimental and control groups, shows that the value is statistically highly significant, as was observed from the unpaired ‘t’ test value of 13.39 with P value of <0.05, which is an evidence indicatingthe effect of Amla juice in reducing postprandial blood glucose levels. The resultsfound that the administration of Amla juice did have aneffect in reducing blood glucose level in the experimental group. By comparing the findings of pre-test and post test between the experimental group and the control group,the effect was identified (assessed). The study concluded that the Amlajuice is effective in reducing blood glucose level.


2021 ◽  
Vol 5 (1) ◽  
pp. 14-25
Author(s):  
Nurul Fadhilah ◽  
Erfiani Erfiani ◽  
Indahwati Indahwati

The calibration method is an alternative method that can be used to analyze the relationship between invasive and non-invasive blood glucose levels. Calibration modeling generally has a large dimension and contains multicolinearities because usually in functional data the number of independent variables (p) is greater than the number of observations (p>n). Both problems can be overcome using Functional Regression (FR) and Functional Principal Component Regression (FPCR). FPCR is based on Principal Component Analysis (PCA). In FPCR, the data is transformed using a polynomial basis before data reduction. This research tried to model the equations of spectral calibration of voltage value excreted by non-invasive blood glucose level monitoring devices to predict blood glucose using FR and FPCR. This study aimed to determine the best calibration model for measuring non-invasive blood glucose levels with the FR and FPCR. The results of this research showed that the FR model had a bigger coefficient determination (R2) value and lower Root Mean Square Error (RMSE) and Root Mean Square Error Prediction (RMSEP) value than the FPCR model, which was 12.9%, 5.417, and 5.727 respectively. Overall, the calibration modeling with the FR model is the best model for estimate blood glucose level compared to the FPCR model.


Author(s):  
Aishwarya Pramod Benkar ◽  
Smita Bhimrao Kanase

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.


1966 ◽  
Vol 52 (3) ◽  
pp. 357-367 ◽  
Author(s):  
Claus Rerup ◽  
Ingmar Lundquist

ABSTRACT Multiple serial blood glucose level determinations in individual mice were performed on small blood samples (10–25 μl) using the orbital bleeding technique. Glucose was determined specifically by a known enzymatic reaction. Blood glucose determined in this way was found a parameter of high reproducibility and precision, the latter being shown by the finding that differences between individual animals were highly significant in practically all the experiments. The standard deviation of the single measurement in normal mice was ± 8.2 mg/100 ml as determined from 600 samples, which indicated that the technique allows of the detection of blood sugar level changes of about 15 mg/100 ml or more with very high significance, in a group of 5 mice. In the sampling procedure as such, intravenous or subcutaneous saline injections did not necessarily have any effect on the blood glucose level, but interpretation of slight blood sugar changes under experimental conditions should always be based on a comparison with control groups, since the latter may sometimes show a slight but significant change. In normal non-fasting mice (NMRI strain) significant differences in homoeostatic blood glucose level adjustments were demonstrated. In acutely adrenalectomized mice blood glucose levels were lower and more variable than in normals. Alloxan injection (70 mg/kg) was followed in individual mice by a triphasic blood sugar response, as is known from other species.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Louis E. Ugahari ◽  
Yanti M. Mewo ◽  
Stefana H.M. Kaligis

Abstract: Blood glucose must be maintained in a constant concentration. Hyperglycemia, an increase of blood glucose level, can be a symptom of diabetes mellitus. One of the factors that affect the blood glucose level is physical activity. Low physical activity can be influenced by work. Sedentary lifestyle is identic with office workes. Office workers do not enough time to do physical activity. This study was aimed to describe the fasting blood glucose level among office workers. This was a descriptive study with a cross sectional design. Respondents were obtained by using total sampling method. There were 52 respondents in this study consisted of 25 males and 27 females. The results showed that 45 respondents (86.54%) had normal fasting blood glucose levels, 5 respondents (9.62%) had high fasting blood glucose levels (hyperglycemia), and 2 respondents (3.84%) had low fasting blood glucose levels (hypoglycemia). The maximum value was 243 mg/dL, the minimum value was 63 mg/dL, the median value was 83 mg/dL, the average value was 94.42 mg/dL, and standard of deviation was 37.85 mg/dL. Conclusion: Most office workers had normal blood glucose levels.Keywords: fasting blood glucose, office workers Abstrak: Glukosa darah dalam tubuh manusia harus dijaga dalam konsentrasi yang konstan. Kadar glukosa darah dalam tubuh yang meningkat (hiperglikemia) dapat menjadi gejala penyakit diabetes mellitus. Salah satu faktor yang memengaruhi kadar glukosa darah ialah aktivitas fisik. Aktivitas fisik yang kurang dapat dipengaruhi oleh pekerjaan. Pola hidup sedentary lifestyle identik dengan pekerja kantor dewasa ini. Pekerja kantor tidak memiliki waktu untuk terlibat dalam aktivitas fisik yang cukup. Penelitian ini bertujuan untuk mengetahui gambaran kadar glukosa darah puasa pada pekerja kantor. Jenis penelitian ialah deskriptif dengan desain potong lintang. Pemilihan responden dilakukan dengan metode total sampling. Responden terdiri dari 25 orang laki-laki s dan 27 orang perempuan. Hasil penelitian mendapatkan 45 responden (86,54%) memiliki kadar glukosa darah puasa normal, 5 responden (9,62%) memilki kadar glukosa darah puasa tinggi (hiperglikemia), dan 2 responden (3,84%) memilki kadar glukosa puasa rendah (hipoglikemia). Hasil pengukuran kadar glukosa darah puasa mendapatkan nilai maksimum 243 mg/dL, nilai minimum 63 mg/dL, nilai median 83 mg/dL, nilai rata-rata 94,42 mg/dL dan standar devisiasi 37,85 mg/dL. Simpulan: Sebagian besar pekerja kantor masih memiliki kadar glukosa darah puasa yang normal. Kata kunci: glukosa darah puasa, pekerja kantor


2018 ◽  
Vol 18 (3) ◽  
pp. 299 ◽  
Author(s):  
Arvind Sharma ◽  
Prasanth Balasubramanian ◽  
Kiran D. Gill ◽  
Ashish Bhalla

Objectives: This study aimed to assess the prognostic significance of blood glucose levels and blood glucose alterations (i.e. hyper- or hypoglycaemia) among patients with aluminium phosphide (AlP) poisoning. Methods: This prospective observational study was conducted at the Postgraduate Institute of Medical Education & Research, Chandigarh, India, between January 2010 and June 2011. All patients presenting to the emergency department with a definitive history of AlP ingestion or symptoms compatible with AlP poisoning were included in the study. Blood glucose levels were recorded at presentation and every six hours thereafter. Alterations in blood glucose levels and other clinical and laboratory variables were subsequently compared between survivors and non-survivors. Results: A total of 116 patients with AlP poisoning were identified. Of these, 57 patients (49%) survived and 59 patients (51%) died. At presentation, the mean blood glucose levels of survivors and non-survivors were 119.9 ± 35.7 mg/dL and 159.7 ± 92.5 mg/dL, respectively (P <0.001). In comparison to the survivors, non-survivors had significantly higher heart rates, total leukocyte counts, blood glucose level alterations and serum creatinine levels (P <0.050). In addition, systolic blood pressure, Glasgow coma scale scores, arterial blood gas pH and bicarbonate values and duration of hospital stay was significantly lower compared to survivors (P <0.001). However, neither blood glucose levels at admission nor blood glucose alterations correlated independently with mortality in a multivariate analysis. Conclusion: The role of blood glucose level alterations in predicting patient outcomes in AlP poisoning cases remains inconclusive. Further studies with larger sample sizes are required.Keywords: Aluminum Phosphide; Poisoning; Blood Glucose; Hyperglycemia; Hypoglycemia; Mortality; Prognostic Factors; India.


Sign in / Sign up

Export Citation Format

Share Document