scholarly journals SOCIAL STRESS FACTORS AS A TRIGGER FOR THE DEVELOPMENT OF ANXIETY AND DEPRESSIVE DISORDERS

2020 ◽  
Author(s):  
Iryna Strelnikova
Keyword(s):  
Social Stress ◽  
Depressive Disorders ◽  
Stress Factors ◽  
Development Of Anxiety

scholarly journals Hereditage and socially stress load in the pathogenesis of recurrent depressive disorders

2021 ◽  
pp. 47-51
Author(s):  
Natalia Maruta ◽  
Svitlana Kolyadko ◽  
Viktoriya Fedchenko ◽  
Olena Cheredniakova
Keyword(s):  
Significant Role ◽  
Psychological Factors ◽  
Social Stress ◽  
Depressive Disorders ◽  
Stressful Events ◽  
Combined Effect ◽  
Stress Factors ◽  
Recurrent Depression ◽  
Stress Load

The paper presents the results of a comprehensive clinical-genealogical, clinical-anamnestic and psychodiagnostic examination of patients with recurrent depression. The features, structure and role of heredity factors and social stress factors in the formation of recurrent depression have been investigated. The presence of a significant family accumulation of depressive disorders in the pedigrees was revealed in patients with recurrent depressive disorders, predominantly in the mother’s line. It was found that an important provoking factor in the development of depressive disorders is the presence of factors of mental traumatization, mainly social and psychological. It has been proved that a significant role in the pathogenesis of depression belongs not to the number of stressful events, but to the level of their stressfulness. The results obtained show that the formation of depressive disorders is determined by the presence of a combined effect of clinical and genealogical, social and environmental and socio-psychological factors.

PERSONALITY PROFILE OF THE NURSE AS A PREDICTOR FOR DEVELOPMENT OF ANXIETY AND DEPRESSIVE DISORDERS

2019 ◽  
Vol 6 (2) ◽  
pp. 21-32
Author(s):  
Azza abou shahda ◽  
Rania El-Etreby ◽  
Hanan Mohamed ◽  
saied ELNagar
Keyword(s):  
Depressive Disorders ◽  
Personality Profile ◽  
Development Of Anxiety

Educational Leadership Sustainability

2017 ◽  
pp. 182-193
Author(s):  
Valerie A. Storey ◽  
Neffisatu J. C. Dambo
Keyword(s):  
Educational Leadership ◽  
Social Stress ◽  
Critical Stress ◽  
Stress Factors ◽  
Life Balance ◽  
Stress Theory ◽  
Accountability Measures ◽  
High Propensity ◽  
The Relationship ◽  
Extended Exposure

Leaders have a high propensity to experience stress due to the design of their career, duties, and accountability measures. Extended exposure to stress without the appropriate resources involves strains that can potentially become burdensome and begin to weigh on an individual. This chapter explores the relationship between wellness and burnout through the application of social stress theory to critical stress factors, as well as suggesting coping strategies for enhancing wellness and maintaining one's life balance.

scholarly journals Affective modulation of the startle response among children at high and low risk for anxiety disorders

2015 ◽  
Vol 45 (12) ◽  
pp. 2647-2656 ◽  
Author(s):  
A. Kujawa ◽  
C. R. Glenn ◽  
G. Hajcak ◽  
D. N. Klein
Keyword(s):  
Anxiety Disorders ◽  
Startle Response ◽  
Depressive Disorders ◽  
Parental Psychopathology ◽  
Affective Modulation ◽  
Early Markers ◽  
History Of ◽  
Picture Viewing ◽  
Underlying Mechanisms ◽  
Development Of Anxiety

BackgroundIdentifying early markers of risk for anxiety disorders in children may aid in understanding underlying mechanisms and informing prevention efforts. Affective modulation of the startle response indexes sensitivity to pleasant and unpleasant environmental contexts and has been shown to relate to anxiety, yet the extent to which abnormalities in affect-modulated startle reflect vulnerability for anxiety disorders in children has yet to be examined. The current study assessed the effects of parental psychopathology on affective modulation of startle in offspring.MethodNine-year-old children (n = 144) with no history of anxiety or depressive disorders completed a passive picture viewing task in which eye-blink startle responses were measured during the presentation of pleasant, neutral, and unpleasant images.ResultsMaternal anxiety was associated with distinct patterns of affective modulation of startle in offspring, such that children with maternal histories of anxiety showed potentiation of the startle response while viewing unpleasant images, but not attenuation during pleasant images, whereas children with no maternal history of anxiety exhibited attenuation of the startle response during pleasant images, but did not exhibit unpleasant potentiation – even when controlling for child symptoms of anxiety and depression. No effects of maternal depression or paternal psychopathology were observed.ConclusionsThese findings suggest that both enhanced startle responses in unpleasant conditions and failure to inhibit startle responses in pleasant conditions may reflect early emerging vulnerabilities that contribute to the later development of anxiety disorders.

scholarly journals Cognitive Vulnerabilities for Depression and Anxiety in Childhood: Specificity of Anxiety Sensitivity and Rumination

2014 ◽  
Vol 44 (1) ◽  
pp. 30-42 ◽  
Author(s):  
Hannah M. Brown ◽  
Richard Meiser-Stedman ◽  
Harriet Woods ◽  
Kathryn J. Lester
Keyword(s):  
Depressive Symptoms ◽  
Anxiety Sensitivity ◽  
Depressive Disorders ◽  
Childhood Anxiety ◽  
Anxiety And Depression ◽  
Cognitive Vulnerabilities ◽  
Presenting Symptoms ◽  
Cognitive Therapies ◽  
Shared Cognitions ◽  
Development Of Anxiety

Background: Childhood anxiety and depression frequently co-occur. Exploring specificity in cognitive processes for anxiety and depression in childhood can provide insight into cognitive vulnerabilities contributing to the development of anxiety and depressive disorders and inform targeted psychological interventions. Anxiety sensitivity and rumination are robust cognitive vulnerabilities for anxiety and depression, respectively. However, despite conceptual similarities, they are rarely considered together within a single study. Aims: The current study explored specific and shared associations between anxiety sensitivity subscales and rumination and anxiety and depressive symptoms in unselected children. Method: Multiple regression analyses explored to what extent specific self-reported anxiety sensitivity subscales (physical, social and mental concerns) and rumination predicted anxiety and depressive symptoms in 147 unselected children, aged 7–11 years. Results: Physical and social concern subscales of anxiety sensitivity were specifically associated with anxiety, whilst rumination was specifically associated with depressive symptoms. The mental concerns subscale of anxiety sensitivity was independently associated with both anxiety and depressive symptoms. These associations were only partially mediated by rumination. Conclusions: Anxiety and depression in young people are characterized by specific and shared cognitions. Evidence for shared and specific associations between the cognitive vulnerabilities of anxiety sensitivity and rumination, and anxiety and depression highlight the utility of transdiagnostic research and confirm that cognitive therapies may benefit from targeting cognitive concerns relating specifically to the patient's presenting symptoms.

scholarly journals GLYPROLINES AS MODULATORS OF IMMUNOREACTIVITY WITHIN CONDITIONS OF “SOCIAL” STRESS

2019 ◽  
Vol 7 (4) ◽  
pp. 224-230
Author(s):  
M. A. Samotrueva ◽  
A. L. Yasenyavskaya ◽  
O. A. Bashkina ◽  
N. F. Myasoedov ◽  
L. A. Andreeva
Keyword(s):  
Social Stress ◽  
Medical Science ◽  
Subsequent Development ◽  
Stress Factors ◽  
Male Rats ◽  
Delayed Type Hypersensitivity ◽  
Control Group ◽  
The Social ◽  
Important Direction ◽  
Induced Immunity

The most important direction in the development of modern medical science is the study of protective, compensatory and pathological reactions of the organism that occur in response to various stress factors.The aim of the study is the subsequent development of methods for pharmacological correction of these reactions. The remedies for the correction of stress-induced immunity disorders are represented by the glyprolin group – the Selank drug and the Pro-Gly-Pro peptide compound – and are of particular interest. The aim of the experiment was to study the immunomodulating effect of glyprolines on the basis of the “social stress” model.Materials and methods. The experiment was performed on non-linear male rats aged 6-8 months. A model of a sensor contact was used as a model of the experimental “social stress”. The animals were divided into groups (n = 10): a “control” group was represented by individuals with aggressive and submissive types of behavior, formed within the conditions of the experimental “social stress” for 20 days; and 2 experimental groups in which the animals were intraperitoneally administered Selank (100 µg/kg) and Pro-Gly-Pro (100 µg/kg) against the background of the experimental “social” stress once a day for 20 days. A functional activity of the immune system was studied on the basis of standard immunopharmacological tests: a delayed-type hypersensitivity test (DTH test), a direct agglutination test (DAT), a latex test for studying the Neutrophil phagocytic rate of peripheral blood, and the essessment of the leucogram.Results. It has been established, that within the conditions of the “social” stress, the changes in the immune response are multidirectional. That fact confirms the theory of “the immune disbalance” caused by the action of stressors. As a result of studying the effect of glyprolines within the conditions of “the social stress”, Selank and Pro-Gly-Pro proved to be effective immunocorrectors, restoring cellular and humoral immunogenesis reactions as well as the phagocytic activity of neutrophils and leucogram indices.Сonclusion. The carried out study expands understanding of the immunoreaction pathogenesis within the stress-induced conditions in order to further develop a pharmacological strategy for correcting the revealed disorders through the substances of the neuropeptide structure.

scholarly journals Quality of life, anxiety and depressive disorders in patients with extrasystolic arrhythmia

2020 ◽  
Author(s):  
Alexey Y. Mikhaylov ◽  
Alexei V. Yumashev ◽  
Eugeny Kolpak
Keyword(s):  
Depressive Disorder ◽  
Depressive Disorders ◽  
Depression Scale ◽  
Depression And Anxiety ◽  
Ventricular Extrasystole ◽  
Significant Difference ◽  
Different Types ◽  
Development Of Anxiety ◽  
Assessment Scales

IntroductionThe aim of this study was to perform a comparative and economic analysis of the degree of development of anxiety-depressive disorder in patients with different types of extrasystolic arrhythmia using different assessment scales.Material and methodsThe study was conducted in 2018–2019 at the premises of clinic No. 4, involving 450 patients (Moscow, Russia). Patients were divided into three groups: with coronary heart disease (CHD) (147 patients), with myocardiodystrophy (MCD) (113) and with cardiopsychoneurosis (CPN) (190). Everyone underwent round-the-clock electrocardiography (ECG) and echocardiography. If symptoms of depressive disorder are detected in a timely manner, the risk of adverse cardiovascular diseases may be reduced.ResultsDepression and anxiety indicators on all three scales differed significantly (p ≤ 0.05) in patients with supraventricular extrasystole (more than 40 points on the Zung scale, 14 points on the Montgomery-Asberg depression scale, more than 38 points on Zung and 3 points on Covi anxiety scales). For patients with ventricular extrasystole, a significant difference was established between groups 1 and 2 only in terms of the level of depression on the Zung scale. Factors of psychogenic origin determine the development of cardiac rhythm disturbances.ConclusionsThe study showed that for supraventricular extrasystoles, these factors determine the overall health of the patient. The differences between the three groups are significant on all scales of depression and anxiety (p ≤ 0.05). The most susceptible to depression and anxiety are patients with extrasystolic arrhythmias diagnosed with CHD, as well as MCD.

scholarly journals Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue

2022 ◽  
Vol 13 (1) ◽  
Author(s):  
Laurence Dion-Albert ◽  
Alice Cadoret ◽  
Ellen Doney ◽  
Fernanda Neutzling Kaufmann ◽  
Katarzyna A. Dudek ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Stress Responses ◽  
Social Stress ◽  
Depressive Disorders ◽  
Brain Regions ◽  
Brain Barrier ◽  
Female Mice ◽  
Blood Brain ◽  
Stressed Female ◽  
Soluble E Selectin

AbstractPrevalence, symptoms, and treatment of depression suggest that major depressive disorders (MDD) present sex differences. Social stress-induced neurovascular pathology is associated with depressive symptoms in male mice; however, this association is unclear in females. Here, we report that chronic social and subchronic variable stress promotes blood-brain barrier (BBB) alterations in mood-related brain regions of female mice. Targeted disruption of the BBB in the female prefrontal cortex (PFC) induces anxiety- and depression-like behaviours. By comparing the endothelium cell-specific transcriptomic profiling of the mouse male and female PFC, we identify several pathways and genes involved in maladaptive stress responses and resilience to stress. Furthermore, we confirm that the BBB in the PFC of stressed female mice is leaky. Then, we identify circulating vascular biomarkers of chronic stress, such as soluble E-selectin. Similar changes in circulating soluble E-selectin, BBB gene expression and morphology can be found in blood serum and postmortem brain samples from women diagnosed with MDD. Altogether, we propose that BBB dysfunction plays an important role in modulating stress responses in female mice and possibly MDD.

Socio-hygienic characteristics of regional middle-level medical personnel

2021 ◽  
pp. 44-49
Author(s):  
Lyudmila Ilyinichna Kaspruk ◽  
Elizaveta Vladislavovna Mitrofanova
Keyword(s):  
Quality Of Life ◽  
Social Stress ◽  
Medical Personnel ◽  
Middle Level ◽  
Stress Factors ◽  
Mean Values ◽  
Factors Affecting ◽  
Sf 36 ◽  
Quality Of Medical Care

The presented study sets out the results of an assessment of a sociological survey of middle-level medical personnel of the Orenburg Region in morphological connection with their quality of life. Information on the factors influencing the quality of medical care provided by medical personnel is provided. The assessment of the main indicators of the quality of life was carried out, revealing minor deviations of the lower limit of normal of the mean values on the SF-36 scales. The authors describe social stress factors affecting the social and hygienic «portrait» of middle-level medical professionals as recipients of medical services.

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