A STUDY ON ASSESSMENT OF RISK FACTORS, COMPLICATIONS AND QUALITY OF LIFE OF PATIENTS WITH HYPOTHYROIDISM IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 38-40
Author(s):  
CH. Sridev ◽  
Samhitha Karnati ◽  
Likhitha Madari ◽  
Liyaqath Ali ◽  
Raviteja Nethula
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Care Hospital ◽  
Inclusion Criteria ◽  
Total N ◽  
Sf 36 ◽  
High Bmi

Background: Hypothyroidism is a syndrome which results from decreased production of thyroid hormones from thyroid gland and hence it can also be termed as underactive thyroid disease. Objectives: To assess the quality of life in patients with denovo hypothyroidism. To assess risk factors, complications in patients with hypothyroidism. Materials and methods: There was a total (N=100) number of participants enrolled in the study and are evaluated for risk factors and complications and among 100, 40 patients are Denovo hypothyroid who are assessed for quality of life. This is a prospective observational study in which the risk factors, complications and quality of life of patients is evaluated for those patients who are willing to give informed consent and meet the inclusion criteria. Results and Discussion: Referring to the ndings, the patients with high BMI, females and age around 20-30 are more prevalent. Patients who do not adhere to medications develop complications such as goiter and cvs problems but mostly obesity is seen and QOL of patients was studied using SF-36 and HADS scales. The initial mean was found to be less compared to the nal mean in SF-36 whereas in HADS the initial mean is high compared to the nal mean. The Patient's BMI was high initially and then reduced to normal.This implies that after educating the patient about the disease and need of medication the nal result shows there is improvement in the patient's QOL. P values of SF 36 and HADS are 0.0001 and 0.0314 respectively, which by conventional criteria was found to be statistically signicant. Conclusion: This study simply showed that the females, patients with high BMI and age around 20-30 are the major risk factors. Proper patient education, care and medication adherence are the cornerstones to help avoid complications and improve patients quality of life.

scholarly journals Quality of life in individuals with cervical dystonia before botulinum toxin injection in a Brazilian tertiary care hospital

2011 ◽  
Vol 69 (6) ◽  
pp. 900-904 ◽  
Author(s):  
Mariana Ribeiro Queiroz ◽  
Hsin Fen Chien ◽  
Egberto Reis Barbosa
Keyword(s):  
Quality Of Life ◽  
Botulinum Toxin ◽  
Cervical Dystonia ◽  
Rating Scale ◽  
Short Form ◽  
Tertiary Care ◽  
Residual Effect ◽  
Care Hospital ◽  
Sf 36

OBJECTIVE: The purpose of this study was to evaluate quality of life (QoL) in a Brazilian population of individuals with cervical dystonia (CD) without effect of botulinum toxin (BTx) or with only residual effect of BTx, and identify possible physical and social aspects that affect their QoL. METHOD: Sixty five out of sixty seven consecutive patients with CD were assessed with two instruments: Short-form Health Survey with 36 questions (SF-36) and Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS). RESULTS: Severity of CD (TWSTRS) correlated moderately with two SF-36 subscale: role-physical (r= -0.42) and body pain (r= -0.43). Women also scored worse in two subscale of SF-36: vitality (p<0.05) and mental-health (p<0.005). CONCLUSION: Severity of CD and gender (female) were the main factors related to a worse QoL perception. These findings may help health professionals to predict which characteristics could lead to worse QoL, and therefore, better target their interventions to lessen the burden caused by CD.

scholarly journals Validation of the hospital frailty risk score in a tertiary care hospital in Switzerland: results of a prospective, observational study

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e026923 ◽  
Author(s):  
Andreas Eckart ◽  
Stephanie Isabelle Hauser ◽  
Sebastian Haubitz ◽  
Tristan Struja ◽  
Alexander Kutz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Score ◽  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Risk Group ◽  
Tertiary Care ◽  
Length Of Hospital Stay ◽  
Adverse Outcomes ◽  
Care Hospital

ObjectivesRecently, the Hospital Frailty Risk Score based on a derivation and validation study in the UK has been proposed as a low-cost, systematic screening tool to identify older, frail patients who are at a greater risk of adverse outcomes and for whom a frailty-attuned approach might be useful. We aimed to validate this Score in an independent cohort in Switzerland.DesignSecondary analysis of a prospective, observational study (TRIAGE study).SettingOne 600-bed tertiary care hospital in Aarau, Switzerland.ParticipantsConsecutive medical inpatients aged ≥75 years that presented to the emergency department or were electively admitted between October 2015 and April 2018.Primary and secondary outcome measuresThe primary endpoint was all-cause 30-day mortality. Secondary endpoints were length of hospital stay, hospital readmission, functional impairment and quality of life measures. We used multivariate regression analyses.ResultsOf 4957 included patients, 3150 (63.5%) were classified as low risk, 1663 (33.5%) intermediate risk, and 144 (2.9%) high risk for frailty. Compared with the low-risk group, patients in the moderate risk and high-risk groups had increased risk for 30-day mortality (OR (OR) 2.53, 95% CI 2.09 to 3.06, p<0.001 and OR 4.40, 95% CI 2.94 to 6.57, p<0.001) with overall moderate discrimination (area under the ROC curve 0.66). The results remained robust after adjustment for important confounders. Similarly, we found longer length of hospital stay, more severe functional impairment and a lower quality of life in higher risk group patients.ConclusionOur data confirm the prognostic value of the Hospital Frailty Risk Score to identify older, frail people at risk for mortality and adverse outcomes in an independent patient population.Trial registration numberNCT01768494; Post-results.

scholarly journals Assessment of medication adherence, quality of life and risk factors among patients with tuberculosis in a South Indian tertiary care hospital: a cross-sectional study

2019 ◽  
Vol 5 (8) ◽  
pp. 213
Author(s):  
Shaik Salma ◽  
Abdul Amreen Siddiqua ◽  
R. S. S. Lakshmi Keerthana ◽  
Meghana Suryadevara ◽  
Dhadala Victor Prabhakar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Medication Adherence ◽  
Psychological Health ◽  
Tertiary Care ◽  
Reliability And Validity ◽  
Care Hospital ◽  
Good Reliability ◽  
High Adherence

<p class="abstract"><strong>Background:</strong> The main objective of the current study was to assess the level of medication adherence, quality of life, risk factors for better treatment outcomes and to improve patient quality of life by giving TB education.</p><p class="abstract"><strong>Methods:</strong> A prospective observational study was conducted on 278 patients (139 tubercular patients and 139 health volunteers). A data collection form of various socio-demographic factors, lifestyle factors, and co-morbid conditions for tuberculosis were collected. The quality of life (QOL) was assessed by interviewing the subjects using WHO-QOL BREF questionnaire. Morisky – 8 item medication Adherence Questionnaire was used for assessing adherence.  </p><p class="abstract"><strong>Results:</strong> In a total of 139 TB patients, high adherence (60.06%), medium adherence (20.86%) and low adherence (10.07%) are reported. WHOQOL-BREF mean domain scores were physical health (54.10±12.33), psychological health (51.73±16.24), social health (62.04±15.35) and environmental health (57.14±16.90) respectively. In present study male (67.63%) are higher than females (32.37%). Risk factors observed in study were statistically significant and discussed in present study.</p><p class="abstract"><strong>Conclusions:</strong> This study showed that the MMAS-8 had good reliability and validity for measuring adherence levels in rural TB patients. There was a high level of adherence to anti-TB treatment was seen in study area. WHO-QOL BREF questionnaire had good reliability and validity for measuring quality of life and Improved quality of life observed in patients with high adherence to anti tubercular drugs. Risk factors such as age, education, locality, food habits, income, smoking and alcoholism are independently associated with Tuberculosis.</p>

scholarly journals QUALITY OF LIFE AFTER PRIMARY PCI IN PAKISTANI POPULATION – DOES IT REALLY CHANGE?

2021 ◽  
Vol 54 (3) ◽  
pp. 224-229
Author(s):  
Rajesh Kumar ◽  
Ali Ammar ◽  
Jehangir Ali Shah ◽  
Tahir Saghir ◽  
Ashok Kumar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Tertiary Care ◽  
Bodily Pain ◽  
Coronary Intervention ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Sf 36

Objectives: To evaluate the quality of life (QOL) after percutaneous coronary intervention (PCI) using short-form health survey (SF-36) questionnaire at a tertiary care hospital in Pakistan. Methodology: It was a cross-sectional study conducted at a tertiary care cardiac center in Pakistan. A total of 433 adult patients who undergone PCI at least six months before were included. The QOL was assessed using Urdu translated version of SF-36 questionnaire. QOL scores were computed on eight domains role physical (RP), role emotional (RE), bodily pain (BP), physical function (PF), mental health (MH), vitality, general health perception (GHP), and social function (SF) along with two summary scores for mental (MCS) and physical component (PPS). Results: The highest mean score was reported for BP (73.8±19.7) followed by PF (61.7±24.3). In comparison to a year before, 52.9% and 24.7% rated their QOL somewhat better and much better respectively. Score for PF, RE, and RF were significantly higher in male, while, vitality was higher for female. Score of PPS was significantly higher for male whereas MCS score was higher for female. An increasing trend, with respect to patients’ perception of QOL compared to an year ago, was observed on five out of eight domains namely GHP, PF, RP, RE, and BP. Conclusion: Improved QOL, compared to a year ago, is reported by most of the patients. An acceptable (>50) mean score was observed on most of the QOL domains of SF-36 and it was found to be positively related to the patient stated degrees of QOL.

scholarly journals Risk factors which affect the change of antibiotics in neonatal pneumonia observed in a tertiary care hospital

2015 ◽  
Vol 6 (1) ◽  
pp. 21-24
Author(s):  
Mirza Md Ziaul Islam ◽  
M Monir Hossain ◽  
Md Abdullah Al Mamun ◽  
Salahuddin Mahmud ◽  
BH Nazma Yasmeen
Keyword(s):  
Risk Factors ◽  
Antibiotic Therapy ◽  
Rural Areas ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Inclusion Criteria ◽  
Laboratory Parameters ◽  
Medical College

Background : Neonatal pneumonia accounts for significant morbidity and mortality specially in developing countries like Bangladesh. Perhaps because of its etiologic complexity, pneumomia in neonates has been relatively refractory to reduce its severity and improve the prognosis. Re- evaluation of the antibiotic therapy is necessary in patients to have at 48 hours after diagnosis. Physician should suspect inappropriate antibiotic therapy in cases with persistence of symptoms.Objective: This study was carried out to find the risk factors (clinical and laboratory parameters) which affect the change of antibiotic in neonatal pneumonia and its effect on morbidity and mortality .Methodology: This prospective observational study was conducted in Dhaka Shishu (children) Hospital from July 2009 to June 2010. A total of 115 neonates who met the inclusion criteria were enrolled in the study. The neonates were managed using a standard protocol. They were closely followed up to see the outcome with the change in antibiotics.Results : Total 115 neonates were admitted with mean age 16.2±5.9 days, mean weight 2857.6±580.6gm,58% were male & 42% female,26% were preterm & 74% were term and majority of them (73%) were from rural areas. Among the neonates, 36 (31,3%) needed a change in antibiotics. Fever, positive CRP, low O2 saturation, low PaO2 , high alveolar-arterial O2 gradient, low arterial-alveloar O2 tension and low pH were significantly associated with change in antibiotics.Conclusion : Addressing the clinical and laboratory parameters appropriately the change in antibiotic in selected cases can reduce both morbidity and mortality of neonates with pneumonia.Northern International Medical College Journal Vol.6(1) 2014: 21-24

Assessment of Quality of Life (QoL) in Systemic Lupus Erythematosus Patients at a Tertiary Care Hospital in Egypt

2019 ◽  
Vol 15 (4) ◽  
pp. 304-311
Author(s):  
Mervat E. Behiry ◽  
Sahar A. Ahmed ◽  
Eman H. Elsebaie
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Tertiary Care ◽  
Damage Index ◽  
Life Questionnaire ◽  
Care Hospital ◽  
Systemic Lupus

: Systemic Lupus Erythematosus (SLE) has a profound impact on quality of life. Objective: The objective of this study was to explore the quality of life among Egyptian SLE patients and to assess its relationships with demographic and clinical features. Methods: One hundred sixty-four SLE patients were recruited for this study. Demographic information; clinical parameters; disease activity, as evaluated by the systemic lupus erythematosus Disease Activity Index; and organ damage, as assessed by the systemic lupus international Collaborative Clinics/American College of Rheumatology Damage Index, were reported. Quality of life was assessed with a quality of life questionnaire specifically designed for patients with systemic lupus erythematosus; the questions are grouped in the following six domains: physical function, sociooccupational activities, symptoms, treatment, mood, and self-image. Higher values indicate poorer quality of life. Conclusion: Poor quality of life among Egyptian SLE patients and disease activity are strongly related to impaired lifestyles in these patients.

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