A COMPARATIVE STUDY TO ASSESS THE EFFICACY OF HYDROXYPROPYLMETHYLCELLULOSE POWDER OVER STEROID SPRAY IN TREATMENT OF ALLERGIC RHINITIS IN THE DEPTT. OF ENT AND HEAD & NECK SURGERY, SILCHAR MEDICAL COLLEGE & HOSPITAL

Objective: To assess the efficacy of Hydroxypropylmethylcellulose powder over steroid nasal spray in treatment of allergic rhinitis. Methods: A prospective study of 60 patients suffering from allergic rhinitis was conducted in the ENT and Head & Neck surgery Department, Silchar medical College and Hospital from April 2018 to August 2018.The study subjects were divided into two groups A and B. Group A was treated with oral antihistaminic and steroid nasal spray, while group B was treated with oral antihistaminics and HYDROXYPROPYLMETHYLCELLULOSE powder nasal spray for 4 weeks. The treatment outcomes were evaluated after 14 days and 28 days from the beginning of treatment, by assessing relief of symptom on a five point scale. Results: There was almost similar score in both the groups ranging between score 3 and 4(i.e., relief of nasal obstruction and sneezing) after 14 days of treatment (62% vs 64%). But after 28 days there was significantly better improvement score of group B study subjects over group A in score 5 (i.e., complete relief from symptoms (83.3% vs. 66.6% ).In both the groups, mild sedation at the beginning of the treatment was reported in some patients, which is a well known side effect of antihistaminics. Conclusion: The result obtained comparing both the groups indicated high efficacy of hydroxypropylmethylcellulose powder over steroid nasal spray in the treatment of allergic rhinitis.

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Comparative clinical evaluation of effect of topical verses systemic anti -allergic drug in allergic rhinitis: a prospective study

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20175615 ◽

2017 ◽

Vol 4 (1) ◽

pp. 141 ◽

Cited By ~ 1

Author(s):

Sunil Kumar Singh Bhadouriya ◽

Mohit Srivastava ◽

Rohit Saxena ◽

Abhinav Srivastava

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Nasal Spray ◽

Complete Response ◽

Group A ◽

Group B ◽

A Prospective Study ◽

Histopathological Results ◽

Post Therapy

Background: Nasal passages form one of the chief sources of contact of the human with his environment. Hence, it is natural that the mucosa of the area is the victim of assault with multitudes of potential allergens. Allergic rhinitis is an inflammatory disease with worldwide prevalence of 10-40%. Allergic rhinitis is a disease with low mortality but significantly lowers the quality of life and functioning. Both oral and intranasal antihistamines are approved for the first-line treatment of allergic rhinitis and both formulations result in a reduction in symptoms and an improvement in quality of life. Methods: The following study was designed to assess the efficacy and safety of the azelastine nasal spray in comparison to levocetrizine in patients with allergic rhinitis. Out of the 68 patients, 34 cases were treated with topical azelastine (group A), while remaining 34 with systemic levocetrizine (group B). The effects of anti-allergic drugs have been studied on the basis of relief of symptoms and change in histopathology. Results: The effect of levocetrizine has been studied on the basis of relief of symptoms and change in histopathology and found to have complete response in 58% and fair response in 23.5% patients of allergic rhinitis. The effect of topical azelastine nasal spray have complete response in 70.5% and fair response in 23.5% patients of allergic rhinitis. Conclusions: Comparing the post therapy clinical and histopathological results in this study, azelastine nasal spray was found to be more effective and safe in the treatment of allergic rhinitis than levocetrizine.

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Clinicopathological study on CSOM: a comparison between tubotympanic and atticoantral variety

Bangladesh Journal of Otorhinolaryngology ◽

10.3329/bjo.v18i2.11991 ◽

2012 ◽

Vol 18 (2) ◽

pp. 138-144 ◽

Cited By ~ 1

Author(s):

Phub Tshering ◽

Md. Abul Hasnat Joarder ◽

M Alamgir Chowdhury ◽

Kanu Lal Saha

Keyword(s):

Hearing Loss ◽

Neck Surgery ◽

College Hospital ◽

Cross Sectional ◽

Suppurative Otitis Media ◽

Medical College ◽

Intracranial Complications ◽

Group A ◽

Group B ◽

Medical University

Introduction: This study aimed to compare the clinico-pathological features of the tubotympanic and atticoantral variety of chronic suppurative otitis media (CSOM).Methods: This was a cross sectional observational study conducted in the department of Otolaryngology Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU) and Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. The study was done over a period of six months and a total of 60 cases were selected. In group A 30 cases of CSOM tubotympanic variety were included while in group B 30 cases of atticoantral variety of CSOM were selected. The two groups were compared with regard to their clinical presentations, the type and degree of hearing loss and their associated complications by taking a detailed history followed by clinical examination and doing the relevant investigations.Results: In group A, the patients presented with a profuse non smelly discharge. All had a central perforation and majority had mild conductive hearing loss. There were no associated complications. In group B, the aural discharge were foul smelling and scanty. The perforations were 66% in the attic while 33.3% had marginal perforations. The hearing loss was mainly conductive in nature but in group B its more severe in degree and also there were more associated severe to profound sensori-neural hearing loss. There were also associated extracranial and intracranial complications in group B patients.Conclusion: The atticoantral variety of CSOM is associated with a foul smelling scanty discharge with severe hearing loss and complications than the tubotympanic variety of CSOM. Therefore early detection becomes essential especially in the primary care setting for appropriate referral to higher centers for better management DOI:http://dx.doi.org/10.3329/bjo.v18i2.11991 Bangladesh J Otorhinolaryngol 2012; 18(2): 138-144

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Endoscopic sinus surgery: experience of 60 cases

Bangladesh Journal of Otorhinolaryngology ◽

10.3329/bjo.v17i2.8849 ◽

1970 ◽

Vol 17 (2) ◽

pp. 104-109

Author(s):

Md Golam Mustafa ◽

Khabiruddin Ahmed ◽

Mahmudal Hasan

Keyword(s):

Endoscopic Sinus Surgery ◽

Neck Surgery ◽

Medical College Hospital ◽

Sinus Surgery ◽

College Hospital ◽

Medical College ◽

Post Operative Period ◽

A Prospective Study ◽

Surgery Department

Objective: To study the quality of life in patient who underwent ESS operation. Design and setting: A prospective study conducted over a period of one(01) year; from July 2004 to June 2005 in Otolaryngology – Head & Neck Surgery Department of Shaheed Suhrawardy Medical College Hospital and Dhaka Medical College Hospital, Dhaka, Bangladesh. Results: Hospital admitted 60(Sixty) cases of ESS patients were included and analyzed. 42 cases were male; whereas 18 cases were female in this study. 21-40 years (44 cases) were the commonest age group of study people. No significant/ alarming complications were recorded during post operative period. Conclusion: Instead of all limitations, outcome of ESS is more acceptable in comparison with conventional sinus surgery. The main symptoms, like nasal obstruction, discharge, headache and facial pain get relieved off dramatically which is compatible with other recognized study. Key words: Endoscopic sinus surgery; open the sinuses; restore normal air flow. DOI: http://dx.doi.org/10.3329/bjo.v17i2.8849 BJO 2011; 17(2): 104-109

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Comparative Study Between Clean Intermittent Self-Catheterization (Cisc) and Continuous Indwelling Catheterization (Cidc) in Relieving Acute Refractory Retention of Urine Due to Benign Enlargement of Prostate (Bep)

Bangladesh Journal of Urology ◽

10.3329/bju.v21i2.49882 ◽

2020 ◽

Vol 21 (2) ◽

pp. 105-110

Author(s):

Md Shawkat Alam ◽

Sudip Das Gupta ◽

Hadi Zia Uddin Ahmed ◽

Md Saruar Alam ◽

Sharif Muhammod Wasimuddin

Keyword(s):

Comparative Study ◽

Acute Urinary Retention ◽

Bladder Capacity ◽

Inclusion Criteria ◽

College Hospital ◽

Medical College ◽

High Incidence ◽

Group A ◽

Group B ◽

Better Than

Objective: To compare the clean intermittent self-catheterization (CISC) with continuous indwelling catheterization (CIDC) in relieving acute urinary retention (AUR) due to benign enlargement of prostate (BEP). Materials and Methods :A total 60 patients attending in urology department of Dhaka Medical college hospital were included according to inclusion criteria ,Patients were randomized by lottery into two groups namely group –A and group –B for CISC and IDC drainage respectively . Thus total 60 patients 30 in each group completed study. Results : Most men can safely be managed as out-patients after AUR due to BPH. The degree of mucosal congestion and inflammation within the bladder was found to be lower in those using CISC and the bladder capacity in these patients was also found higher.Patients with an IDC had a high incidence of UTIs then that of patients with CISC. During the period of catheterization the incidence of UTI was 43.3% in group B in comparison to 40% in group A; before TURP 36% in group B in comparison to 10% incidence in group A.According to patient’s opinion CISC is better than IDC in the management of AUR. Experiencing bladder spasm, reporting blood in urine, management difficulties, incidence and severity of pain were less in CISC group, and the method of CISC was well accepted by patients as well as their family members. Conclusion: From the current study it may be suggested that CISC is better technique for management of AUR patient due to BPH than IDC. It can also be very helpful when surgery must be delayed or avoided due to any reasons in this group of patients. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.105-110

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Association of Adverse Outcomes in Patients with Cirrhosis Presented with COVID-19

10.53350/pjmhs211551134 ◽

2021 ◽

Vol 15 (5) ◽

pp. 1134-1135

Author(s):

M. A. Chhutto ◽

A. H. Mugheri ◽

A. H. Phulpoto ◽

I. A. Ansari ◽

A. Shaikh ◽

...

Keyword(s):

Liver Disease ◽

Chronic Liver Disease ◽

Adverse Outcomes ◽

Chronic Liver ◽

P Value ◽

College Hospital ◽

Medical College ◽

Group A ◽

Group B ◽

Disease Study

Objective: To determine the association of adverse outcomes in term of mortality in patients with cirrhosis presented with coronavirus disease. Study Design: Retrospective/observational study Place and Duration of Study: Department of Medicine, Chandka Medical College Hospital, Larkana from 1st March 2019 to 31st December 2020. Methodology: Two hundred and twenty covid-19 patients of both genders with or without chronic liver disease were enrolled in this study. Patients were categorized in to two groups. Group A (with cirrhosis 60 patients) and group B (without cirrhosis 60 patients). Outcomes in term of mortality between both groups were examined. Results: There were 38 (63.33%) males and 22 (36.67%) were females with mean age 46.14±8.44 years in group A while in group B, 40 (66.67%) and 20 (33.33%) patients were males and females with mean age 45.26±9.34 years. Patients with cirrhosis had high mortality rate as compared to patients without cirrhosis (33.33% Vs 13.33%) with p-value 0.0001. Conclusion: A significant association of adverse outcomes was found in cirrhotic patients with coronavirus disease. Keywords: Chronic Liver Disease, Corvid-19, Mortality

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Frequency of port site infection following gall bladder removal through Epigastric vs Umbilical port.

The Professional Medical Journal ◽

10.29309/tpmj/2021.28.03.6309 ◽

2021 ◽

Vol 28 (03) ◽

pp. 277-281

Author(s):

Bushra Shaikh ◽

Imamuddin Baloch ◽

Azhar Ali Shah ◽

Abdul Sami Mirani ◽

Parkash Lal Lund ◽

...

Keyword(s):

Laparoscopic Cholecystectomy ◽

Gall Bladder ◽

Wound Infection ◽

Port Site ◽

Site Infection ◽

College Hospital ◽

Medical College ◽

Duration Of Surgery ◽

Group A ◽

Group B

Objective: To compare the frequency of port site wound infection following gall bladder removal through umbilical and epigastric port in laparoscopic cholecystectomy. Study Design: Randomized Control Trial. Setting: Surgical Unit 2, Ghulam Muhammad Mahar Medical College, hospital Sukkur. Period: 1st November 2019 to 30th October 2020. Material & Methods: All cases who underwent four port laparoscopic cholecystectomy were enrolled in two groups. All procedures were performed under general anesthesia. As the last event of surgery gall bladder was retrieved in a glove bag through umbilical port in group A and through epigastric port in group B, both under direct camera vision. Wound infection was considered if there was 3 to 5 grade of wound according to Southampton wound grading system (Figure-1) on 5th postoperative day. All demographics and outcome variables were recorded. Results: Age ranged from 20 to 60 years with mean age of 38.875±8.11 years, BMI 29.973±5.12 Kg/m2, duration of surgery 50.656±8.41 mins and Southampton score was 1.044±1.07 in Group A and mean age of 38.560±6.23 years, BMI 27.437±5.04 Kg/m2, duration of surgery 48.920±8.67 mins and Southampton score was 0.856±0.92 in Group B. In group A, 18 (5.7%)patients developed port site wound infection in contrast to 5 (1.6%) patients in group B (P= 0.006). Conclusion: We conclude that epigastric port retrieval of gall bladder following laparoscopic cholecystectomy results in less port site infection.

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“A PROSPECTIVE STUDY: ROLE OF TRACTION ON FOLEY’S CATHETER IN TURP PATIENTS”

10.36106/8221806 ◽

2021 ◽

pp. 27-29

Author(s):

Prashant Lavania ◽

Ankush Gupta ◽

Rahul Chaudhary

Keyword(s):

Blood Loss ◽

Early Discharge ◽

Common Condition ◽

Medical College ◽

Duration Of Hospital Stay ◽

Group A ◽

Foley’S Catheter ◽

Group B ◽

A Prospective Study

INTRODUCTION: Benign prostatic hyperplasia (BPH) is the most common condition affecting men those are 50 years of age and above.TURP is still the widely used technique for management of BPH. TURPwith advent of newer technologies in diathermy and visual scope, has turned into a relatively safe one. AIM:To study role of catheter traction on blood loss and complications in patients with TURP. MATERIALS AND METHODS: This study was done among patients of BPH admitted in the Department of Surgery at S.N. Medical College, Agra during the period from January 2019 to February 2020. Total 60 cases were enrolled in the study and divided into two groups. Group A(30 patients) with traction on catheter after TURPand Group B(30 patients) without traction on catheter. DISCUSSION: Blood loss and irrigation uid was signicantly less in the group with traction on foley's catheter. Duration of hospital stay and complications were also lesser in group with traction. CONCLUSION: Traction on foley's catheter post TURP is effective in managing BPH with the merits of higher safety due to less blood loss and early discharge.

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Role of Combined Mifepristone and Misoprostol Verses Misoprostol Alone in Induction of Labour in Patients with Intrauterine Foetal Death - a Randomized Comparison Between their Outcome

Anwer Khan Modern Medical College Journal ◽

10.3329/akmmcj.v8i1.31658 ◽

2017 ◽

Vol 8 (1) ◽

pp. 50-54

Author(s):

Sharmin Abbasi ◽

Sehereen Farhad Siddiqua ◽

Mohammad Noor A Alam ◽

Suha Jesmin ◽

Md Mahmudur Rahman Siddiqui ◽

...

Keyword(s):

Fetal Death ◽

Research Work ◽

Medical College Hospital ◽

Induction Of Labour ◽

Intrauterine Fetal Death ◽

College Hospital ◽

Medical College ◽

Misoprostol Group ◽

Group A ◽

Group B

Background: Intrauterine fetal death is means- intrapartum death after the fetus has reached the age of viability8. As in IUFD journey, labor pain will be fruitless. So, it is of utmost importance to search for the method which can reduce hours of pain in labor of IUFD cases.Metarials Methods: In this research work patients divided in two groups. Induction of labour in one group was given by combination of mifepristone and misoprostol other group by misoprostol only and we try to find out the best method. To compare the effectiveness, induction to delivery interval, safety and side effects of combination of mifepristone and misoprostol versus conventional use of misoprostol alone in induction of labour in patients with intrauterine fetal death. It is a Prospective randomized comparative study in Anwer Khan Modern Medical College Hospital and Dhaka Medical College Hospital among 70 patients with IUFD after 28 weeks of gestation during January 2014- January 2016.Result: We allowed the patients up to third gravid and after 28 weeks of gestation. Patients were grouped as Group A(35) & Group B (35). In Group A Induction was given by single oral dose of 200 mg mifepristone, and after 48 hours, tab. Misoprostol in post. fornix started if <34 weeks-100 ?gm dose and >34 weeks-50 ?gm dose. Doses were repeated every 6 hourly intervals if required. In Group B Induction was given by 100 ?gm misoprostol at 6 hourly interval in post. Fornix. In both groups we allowed misoprostol maximum 600 ?gm. Oxytocin was given for augmentation if needed. The two study groups did not differ demographically. Induction to delivery time was shorter with combined regimen group (P<0.001). Induction to delivery interval ranges from 10-12 hours in mifepristone plus misoprostole group.In only misoprostol group it was about 24-26 hours. Doses of misoprostol was lower in combined group (P<0.001). 4 patients need Oxytocin for augmentation in only misoprostol group. In combined group oxytocin was not needed. The two groups did not differ as regards complications experienced during labour and delivery significantly. In overall out come 2 failed induction in misoprostol only group but not in combinedgroup.Conclusion: In Induction of IUFD mifepriston plus misoprostol is an effective combined group. It is safe, non invasive, easily tolerable, highly cost effective, had less induction to delivery interval, required less dose of misoprostol and no need of augmentation with oxytocin. So,the combined group is more effective than conventional regimen of misoprostol alone.Anwer Khan Modern Medical College Journal Vol. 8, No. 1: Jan 2017, P 50-54

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A Comparative Study of Efficacy and Safety Between Tamsulosin and Terazosin in the Treatment of Symptomatic Benign Prostatic Hyperplasia

Chattagram Maa-O-Shishu Hospital Medical College Journal ◽

10.3329/cmoshmcj.v15i1.28755 ◽

2016 ◽

Vol 15 (1) ◽

pp. 17-21

Author(s):

Sakhawat Mahmud Khan ◽

Md Matiar Rahaman Khan ◽

Shahin Akhter ◽

Md Mizanur Rahman

Keyword(s):

Benign Prostatic Hyperplasia ◽

Prostatic Hyperplasia ◽

Common Disease ◽

Efficacy And Safety ◽

College Hospital ◽

Symptomatic Benign Prostatic Hyperplasia ◽

Group A ◽

Group B ◽

A Prospective Study

Background: Lower urinary tract symptoms suggestive of symptomatic Benign Prostatic Hyperplasia (BPH) are a very common disease in elderly men .The incidence of benign prostatic hyperplasia is age related.Objectives: To compare the efficacy and safety of Tamsulosin and Terazosin in the treatment of symptomatic Benign Prostatic Hyperplasia.Methods: This was a prospective study carried out in the Department of Urology, Chittagong Medial College Hospital, Chittagong, Bangladesh during the period of July to December 2014. Total 40 patients of 45-80 years of age were consequently selected according to inclusion criteria. After completion of baseline clinical evaluation and investigations, participants were divided into two groups, group A and group B. Group A (n=20) was given Terazosin 1mg daily for 3 days at bed time and then 2 mg daily at bed time for 2 months. Group B (n=20) was given Tamsulosin, 0.4 mg per day for 2 months. Efficacy was evaluated of each group after 2 month follow up and lastly a comparison was made between them. The parameters monitored were International Prostate Symptoms Score (IPSS) Maximum urine flow rate (Qmax) and Post Voidal Residual Volume (PVR). Tamsulosin 0.4 mg and Terazosin 2 mg once daily for 8 weeks both are effective in relieving symptoms of BPH but Tamsulosin is superior to Terazosin in improvement of total IPSS (p<0.001) and Qmax (p<0.01) PVR (p<0.01) at the end point.Results: Outcome of parameters at follow up after 2 months. Tamsulosin group showed significant improvement of IPSS (p<0.05) PVR (p<0.001) and Qmax (p<0.001) than Terazosin. The incidence of adverse events by administration of Tamsulosin was less than that by Terazosin.Conclusion: Tamsulosin appears to have more efficacy and safety than Terazosin in symptomatic BPH.Chatt Shi Hosp Med Coll J; Vol.15 (1); Jan 2016; Page 17-21

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Prevalence and Management of Otitis Media with Effusion Amongst the School Going Children of a Rural Area in Puducherry

Bengal Journal of Otolaryngology and Head Neck Surgery ◽

10.47210/bjohns.2016.v24i1.68 ◽

2016 ◽

Vol 24 (1) ◽

pp. 21-28 ◽

Cited By ~ 1

Author(s):

Sharath Babu K ◽

Jayagar Prabakaran ◽

Shankar Radhakrishnan

Keyword(s):

Otitis Media ◽

Otitis Media With Effusion ◽

Pure Tone Audiometry ◽

Developed Countries ◽

Wide Field ◽

Age Group ◽

College Hospital ◽

Medical College ◽

Group A ◽

Group B

Background : Otitis Media with Effusion(OME) also known as Secretory Otitis Media, has been identified as the commonest middle ear condition causing deafness in children in developed countries. Neither the indication for surgical treatment nor the types and number of procedures used are uniform. Possible treatment includes myringotomy with or without insertion of ventilation tube either alone or with adenoidectomy and occasionally tonsillectomy. Aims and Objectives : To assess the prevalence and the different modes of presentation of Otitis Media with Effusion among the rural school children of Puducherry and to assess the improvement in hearing after 6 months of surgical intervention done on patients with Otitis Media with Effusion. Materials and Methods: A school screening camp was conducted on 600 children in the age group of 5-12 years in a government middle school near our medical college hospital for identifying children with Otitis Media with Effusion. Students with Otitis Media with Effusion were further classified into 4 groups for various interventional procedures namely adenotonsillectomy with bilateral grommet insertion (Group A), adenoidectomy with bilateral grommet insertion (Group B), bilateral grommet insertion (Group C), bilateral myringotomy with wide field incision in the antero-inferior quadrant (Group D). Result : The prevalence was almost in equal proportions in the age group between 5-12 years and the overall prevalence of Otitis Media with Effusion among the study population was 13.3%. The adenotonsillectomy with bilateral grommet insertion procedure had shown a significant improvement in hearing, which was measured by using pure tone audiometry by assessing the mean air-bone gap, which was 9.81, 8.27 and 6.73 at the end of 6 weeks, 3 months and 6 months respectively, when compared to the other procedures. Conclusion : Adenotonsillectomy with bilateral grommet insertion should be considered in a child with Otitis Media with Effusion who is at risk for speech/language/hearing loss.

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