scholarly journals Chemistry analytical, fish micronuclei and onion chromosome damage for assessing treatment effect SBR in the Domžale–Kamnik central WWTP and quality of river Kamniška Bistrica

Caryologia ◽  
2021 ◽  
Author(s):  
Peter Firbas

Abstract  The aim of this study was to evaluate the cytotoxic and genotoxic potential of the wastewater (WW), the effectiveness of the treatment used by the wastewater treatment plant (WWTP) with sequential batch reactors (SBR) technology, and whether its final treated effluent (FTE) can compromise the water quality of the river at the location where it is discharged. We focused our research on six examples. For analytical chemistry and Allium metaphase (M) test all six samples were collected. Of these, three are so-called biotechnological patterns (WW, WW after mechanical step treatment and FTE), and three are natural riverine environmental patterns. For the micronucleus (MN) test, fish specimens were collected from three sites in the river Kamniška Bistrica. The first two sites locations are up and down the FTE outlet. Results from these areas were compared to the third site (not polluted) reference site, the so-called natural control group. Complementary study with analytical chemistry and biological tests shows that the treatment effect SBR in the Domžale–Kamnik central WWTP carried effectively proved to be efficient for the removal of the cytogenotoxic substances in treated effluent and  consequently in aquatic environment.

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Anders Galaasen Bakken ◽  
Andreas Eklund ◽  
Anna Warnqvist ◽  
Søren O’Neill ◽  
Iben Axén

Abstract Background Recurrent or persistent neck pain affects a vast number of people globally, leading to reduced quality of life and high societal costs. Clinically, it is a difficult condition to manage, and treatment effect sizes are often moderate at best. Activity and manual therapy are first-line treatment options in current guidelines. We aimed to investigate the combination of home stretching exercises and spinal manipulative therapy in a multicentre randomized controlled clinical trial, carried out in multidiscipline ary primary care clinics. Methods The treatment modalities utilized were spinal manipulative therapy and home stretching exercises compared to home stretching exercises alone. Both groups received 4 treatments for 2 weeks. The primary outcome was pain, where the subjective pain experience was investigated by assessing pain intensity (NRS − 11) and the quality of pain (McGill Pain Questionnaire). Neck disability and health status were secondary outcomes, measured using the Neck Disability Indexthe EQ-5D, respectively. One hundred thirty-one adult subjects were randomized to one of the two treatment groups. All subjects had experienced persistent or recurrent neck pain the previous 6 months and were blinded to the other group intervention. The clinicians provided treatment for subjects in both group and could not be blinded. The researchers collecting data were blinded to treatment allocation, as was the statistician performing data analyses. An intention-to-treat analysis was used. Results Sixty-six subjects were randomized to the intervention group, and sixty-five to the control group. For NRS − 11, a B-coefficient of − 0,01 was seen, indication a 0,01 improvement for the intervention group in relation to the control group at each time point with a p-value of 0,305. There were no statistically significant differences between groups for any of the outcome measures. Conclusion Based on the current findings, there is no additional treatment effect from adding spinal manipulative therapy to neck stretching exercises over 2 weeks for patients with persistent or recurrent neck pain. Trial registration The trial was registered 03/07/2018 at ClinicalTrials.gov, registration number: NCT03576846.


2021 ◽  
Vol 12 ◽  
Author(s):  
Hervé Platel ◽  
Marie-Loup Eustache ◽  
Renaud Coppalle ◽  
Armelle Viard ◽  
Francis Eustache ◽  
...  

Despite severe amnesia, some studies showed that Alzheimer Disease (AD) patients with moderate to severe dementia keep a consistent, but impoverished representation of themselves, showing preservation of the sense of identity even at severe stages of the illness. Some studies suggest that listening to music can facilitate the reminiscence of autobiographical memories and that stimulating autobiographical memory would be relevant to support the self of these patients. Consequently, we hypothesized that repeated participation to reminiscence workshops, using excerpts of familiar songs as prompts would participate to the enrichment of autobiographical memories, self-representation and sense of identity. We included a group of 20 AD patients with severe dementia residing in nursing homes. Their performances were compared to a control group of 20 matched (age, education, mood) healthy residents living in the same institutions. The experiment was conducted in three phases over a 2-week period. On phase 1, an individual assessment of sense of identity was proposed to each participant. On phase 2, participants joined musical reminiscence workshops (six sessions over 2 weeks for AD patients and 3 sessions over a week for controls). During the third phase (12 days after the first assessment), individual evaluation of autobiographical memory and a second assessment of sense of identity were proposed. Our results showed that, despite their massive amnesia syndrome, autobiographical memories of AD reached at the end of the 2 weeks the number and quality of those of matched controls. Moreover, we confirmed a continuity of self-representation in AD patients with a stable profile of the answers between the first and second individual assessments of sense of identity. However, the increase in number and episodic quality of autobiographical memories was not accompanied by an enrichment of the sense of identity. In a complementary study, new patients participated in the same paradigm, but using movie extracts as prompts, and showed very similar effects. We discuss all of these results with regard to the literature showing the significant impact of repetition on the reactivation of memory traces even in very amnestic AD patients at severe stages of the disease.


2001 ◽  
Vol 43 (10) ◽  
pp. 117-124 ◽  
Author(s):  
A. Bahri ◽  
C. Basset ◽  
F. Queslati ◽  
F. Brissaud

In Tunisia, golf courses are irrigated with secondary treated effluent stored in landscape impoundments. The impact of the conveyance and storage steps on the physical-chemical and biological quality of irrigation water was evaluated on three golf courses over two years. It was found that the water quality varies all along the water route, from the wastewater treatment plant up to the irrigation site: nutrient and bacteria contents decreased along the route in the three cases. This variation depends on the wastewater quality, the length of the pipes conveying water, the number of regulation reservoirs and ponds, the water residence time in pipes, reservoirs and ponds, and the operation of the ponds. The bacteriological quality of irrigation water deteriorates during the irrigation period in the three golf courses as the ponds are operated as continuous flow reactors. The results obtained in this study indicate the inability of golf water supplies, as currently managed, to properly sanitize reclaimed wastewater and meet target quality criteria recommended by WHO (1989) for water intended for recreational use. For a safe reuse of reclaimed wastewater for golf course irrigation, changes in the design and operation of the ponds should be planned or additional treatment steps provided.


2020 ◽  
Vol 9 (11) ◽  
pp. e1749119607
Author(s):  
Renata Cristina Defiltro ◽  
Patricia Glombowsky ◽  
Lilian Kolling Girardini ◽  
Julcimar Machado Maciel ◽  
Marcelo Vedovatto ◽  
...  

The aim of this study was to determine whether the addition of a homeopathic product to dairy cow feed would improve health and production efficiency, as well as composition and quality of milk. The product tested here was produced to stimulate immunity and indirectly to prevent the colonization of the mammary gland by bacteria, thereby decreasing somatic cell counts and bacteria in cow’s milk. Fifty dairy cows were used, divided into two groups: Control (n = 25) and Treated (n = 25). For 90 consecutive days, 50 grams of homeopathic product (treated group) was added to the concentrate; 50 g of the product vehicle (limestone) was added to the concentrate of the control cows. We performed composition and quality analysis on the milk (days 1, 15, 30, 45, 60, 75, and 90) as well as blood collection to carry out hematological and metabolism analyses (days 1, 30, 60, and 90). We found that fat content in the milk cows consuming the homeopathic agent was greater than that of the control group. Because of this increased fat content, there was a tendency towards higher total solids content in treated cows. A treatment effect was found in terms of total bacterial count (TBC); that is, there were lower TBCs in milk of treated animals than in control animals. There was a trend of a treatment effect versus day for somatic cell count (SCC); that is, there were lower SCC in animals that consumed the homeopathic on days 15 and 30 of the experiment. There was no difference between groups in terms of milk production; however, there was a negative correlation between milk production and TBC or SCC in the milk of cows that consumed homeopathic product. Animals in the treated group had lower total leukocyte and lymphocyte counts than did the control group, as well as a tendency toward lower neutrophil counts in these animals. Several bacteria were isolated from the cows' milk during the experimental period, with no treatment effect. In particular, we isolated Corynebacterium spp., Staphylococcus aureus, Staphylococcus epidermidis and Staphylococcus hyicus in greater numbers of cows compared to other etiologic agents. Based on these results, we conclude that consumption of the homeopathic product by dairy cows had positive effects on milk quality.


2020 ◽  
Vol 8 (1) ◽  
pp. 63
Author(s):  
Ni Nyoman Nepi Marleni ◽  
Ristie Ermawati ◽  
Nitis Aruming Firdaus

<span>The water demands for agricultural purposes are increasing along with the population growth. Unfortunately, the water source is not sufficiently available nowadays. Furthermore, the quality of available water is more deteriorated due to the contamination from many sources such as households, industrial areas and other activities. Water board Scheldestromen handles 16 wastewater treatment plants located in Province of Zeeland in The Netherlands. The total production of treated effluent water from 16 wastewater treatment plants is 50 million annually. Quality of the effluent is relatively good, however, some potential risks related to the number of pathogenic microorganism and some trace metals are still there. The treated effluent is mostly discharged to river near to the treatment plant. The high amount of effluent discharge would potentially to be re-used for fulfill the demand for agricultural water. Therefore, this study aims to evaluate the feasibility of treated effluent from one of Walcheren wastewater treatment plants located in Ritthem, Province of Zeeland.</span><span>This study uses the method of Multi Criteria Analysis (MCA) for looking the best way to re-use the effluent for agricultural purposes. The MCA questionnaire was developed based on the thorough literature review of effluent reuse. There are 6 criteria that need to be weighted and 6 scenario alternatives that need to be scored for the MCA questionnaire. The result show that the effluent water contained pathogenic bacteria (E.Coli) and some trace metals (Ni and Cu) more than suggested by FAO standard. Hence the most preferred technology is combination between closed conduits and UV system, with weighted score 0.78 while others had less weighted score compared to the selected one</span>


Author(s):  
Dhanraj M R ◽  
◽  
Ganesha A ◽  

The aim of this study is to evaluate the quality of sewage generated from 7000 KLD Sewage Treatment Plant (STP) located at Manipal Institute of Technology, Manipal Karnataka which is based on the Activated Sludge Technology. The study of sewage quality of this plant is essential as most of the treated effluent discharged into a stream during monsoon and remaining season used for a Gardening purpose. Water samples were collected from the outlet and analyzed for the major waste-water quality parameters, such as pH, Biochemical Oxygen Demand (BOD) and residual chlorine. The overall quality of sewage of 7000 KLD Sewage treatment plants will be evaluated by collecting samples. The results of these evaluations also determine whether the effluent discharged into the water body is under limits given by Karnataka state pollution control board (KSPCB) & BIS standards.


2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20556-e20556
Author(s):  
T. V. Darling ◽  
K. M. Mustian ◽  
C. E. Heckler ◽  
L. J. Peppone ◽  
M. C. Janelsins ◽  
...  

e20556 Background: While advances in cancer treatment can increase breast cancer (BC) survival, cancer treatment side effects can decrease quality of life (QOL). Cancer cardiotoxicity is a major side effect of chemotherapy and radiotherapy that leads to cardiovascular disease (CVD). The combined burden of cancer and cancer cardiotoxicity drastically affects QOL. Cytokine-mediated inflammatory profiles are dysregulated by cancer treatments and are implicated in the pathogenesis of CVD. Tai Chi Chuan (TCC), an exercise mode with an energy expenditure equivalent to brisk walking, has been shown to improve cardiovascular function and QOL among BC survivors. The purpose of this pilot study was to explore how TCC affects cytokines and how cytokine changes are related to QOL changes among BC survivors. Methods: This pilot study compared the effects of 12 weeks (3, 60 min. sessions/week) of TCC with support therapy on IL-2 and IL-8 and on QOL among 21 BC survivors (mean age=51; range 33–78). Cytokine responses were obtained via serum ELISA and QOL were assessed via the FACIT measurement system pre- and post-intervention. Results: Mean levels of IL-2 decreased in the TCC group (CS=-8.82) but increased in the control group (CS=4.60). Mean levels of IL-8 increased in the TCC group (CS=0.32) but decreased in the control group (CS=-3.82). ANCOVA, controlling for baseline, revealed no treatment effect for IL-2 but there was a statistical trend suggesting a possible treatment effect and baseline interaction for IL-8 (p=0.1). Bivariate analyses revealed a negative association between overall QOL and IL-8 (p=0.07), functional QOL (e.g. ability to work) and IL-8 (p=0.03), as well as physical QOL (e.g. energy level) and IL-8 (p=0.01) in the TCC group. Correlations also showed a negative association between overall QOL and IL-2 (p=0.05) and between functional QOL and IL-2 (p=0.005) among the control group. Conclusions: These findings suggest that TCC-induced changes in cytokines may be associated with changes in QOL, specifically in the physical and functional domains. Future research is needed to verify these pilot study findings and should focus on cardiotoxic effects associated with physical and functional QOL. NCI grant 1R25-CA102618 and Sally Schindel Cone. No significant financial relationships to disclose.


1994 ◽  
Vol 29 (9) ◽  
pp. 99-104 ◽  
Author(s):  
I. Hadjivassilis ◽  
L. Tebai ◽  
M. Nicolaou

The treatment plant has been designed and installed for the treatment of wastewater discharged from various industries at Limassol Industrial Estate. The total daily flow and biological load after the last extension of the plant are 1000-1200m3/d and 220-264kg BOD5/d respectively. Chemical treatment followed by biological treatment is applied. The main steps of the treatment process are as follows: equalization, flotation, coagulation-flocculation, settlement of chemical sludge, pH-adjustment, nutrient addition, aeration of activated sludge, settlement of biological sludge, chlorination and sludge stabilization. The efficiency of the plant with respect to BOD5 and COD removal is over 90%. The quality of the treated effluent is BOD5 &lt; 15mg/l and COD &lt; 40mg/l. The concentration of trace elements are below the recommended limits for reclaimed water used for irrigation purposes.


2002 ◽  
Vol 61 (3) ◽  
pp. 139-151 ◽  
Author(s):  
Céline Darnon ◽  
Céline Buchs ◽  
Fabrizio Butera

When interacting on a learning task, which is typical of several academic situations, individuals may experience two different motives: Understanding the problem, or showing their competences. When a conflict (confrontation of divergent propositions) emerges from this interaction, it can be solved either in an epistemic way (focused on the task) or in a relational way (focused on the social comparison of competences). The latter is believed to be detrimental for learning. Moreover, research on cooperative learning shows that when they share identical information, partners are led to compare to each other, and are less encouraged to cooperate than when they share complementary information. An epistemic vs. relational conflict vs. no conflict was provoked in dyads composed by a participant and a confederate, working either on identical or on complementary information (N = 122). Results showed that, if relational and epistemic conflicts both entailed more perceived interactions and divergence than the control group, only relational conflict entailed more perceived comparison activities and a less positive relationship than the control group. Epistemic conflict resulted in a more positive perceived relationship than the control group. As far as performance is concerned, relational conflict led to a worse learning than epistemic conflict, and - after a delay - than the control group. An interaction between the two variables on delayed performance showed that epistemic and relational conflicts were different only when working with complementary information. This study shows the importance of the quality of relationship when sharing information during cooperative learning, a crucial factor to be taken into account when planning educational settings at the university.


Author(s):  
Yu. V. Antonova ◽  
A. M. Iskandarov ◽  
I. B. Mizonova

Introduction.Coccygodynia is a multidisciplinary disease which is diffi cult to treat. It seriously limits the ability to work and signifi cantly affects the quality of life of patients. The study of somatic dysfunctions in patients with coccygodynia and the analysis of the results of osteopathic treatment of such patients makes it possible to justify the necessity of osteopathic correction of coccygodynia.Goal of the study— to determine the structure of the leading somatic dysfunctions in patients with coccygodynia and to study the effectiveness of osteopathic treatment of this pathology.Materials and methods.The study involved 44 patients from 25 to 65 years old, randomly divided into two groups. The main group of 24 people (20 women and 4 men) received osteopathic treatment, in accordance with the identifi ed leading somatic dysfunctions. Patients of the control group (16 women and 4 men) were treated locally with soft manual techniques (the treatment area was limited by the pelvic region). In order to assess the results of the treatment, we examined the intensity of the pain syndrome and the psycho-emotional state of patients. The severity of the pain syndrome was assessed in accordance with the visual analogue scale (VAS). The psycho-emotional state (with physical and mental components) was assessed with the help of the SF-36 quality of life questionnaire.Results.Somatic dysfunctions typical for patients with coccygodynia have been identifi ed. Osteopathic treatment has proven to be more effective in comparison with local manual therapy of coccygodynia both in early periods and in 3 months after the end of the treatment course.Conclusion.Osteopathic treatment of post-traumatic coccygodynia is effective, and can be recommended for treatment of such patients.


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