scholarly journals ASSESSMENT OF KNOWLEDGE ABOUT VITAMIN-D DEFICIENCY AMONG UNDERGRADUATE STUDENTS IN PRIVATE SECTOR UNIVERSITY

2015 ◽  
Vol 4 (2) ◽  
pp. 26-31
Author(s):  
Beenish Zafar ◽  
Aysha Zia Qureshi ◽  
Sejaa Zafar
Keyword(s):  
Vitamin D ◽  
Private Sector ◽  
Vitamin D Deficiency ◽  
Undergraduate Students ◽  
Descriptive Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Low Mood ◽  
Adults And Children ◽  
Structured Questionnaire

BACKGROUND Vitamin-D commonly known as Ergocalciferol (vitamin D2) & Cholecalciferol (vitamin D3) promotes the absorption and metabolism of calcium. Among children scarcity of vitamin D may cause rickets whereas osteomalacia both in adults and children having relevance with less circulating concentrations of 25OHD that is less than 20 nmol/L. OBJECTIVE To assess knowledge of undergraduate students about vitamin-D deficiency in various private sector universities of Karachi. STUDY DESIGN A cross-sectional study was conducted where structured questionnaire were distributed STUDY SETTINGS & PARTICIPANTS The targeted population was 100 subjects currently enrolled in medical universities. RESULTS According to the descriptive analysis, 100% students were aware of the importance of Vitamin D. However, only 38% of them knew that the deficiency of Vitamin D can cause tiredness, low mood, muscle and bone pain. 64% knew the beneficence of exposure of 10-15% of sunlight. CONCLUSION Students of private medical universities are aware of Vitamin D deficiency and its importance but its implementation is absent. Keywords Osteomalacia, Rickets, Vitamin D Deficiency, Osteoid, Trabecular Bone, Cholecalciferol, Ergocalciferol

scholarly journals Vitamin D deficiency as adverse drug reaction? A cross-sectional study in Dutch geriatric outpatients

2016 ◽  
Vol 72 (5) ◽  
pp. 605-614 ◽  
Author(s):  
A. C. B. van Orten-Luiten ◽  
A. Janse ◽  
R. A. M. Dhonukshe-Rutten ◽  
R. F. Witkamp
Keyword(s):  
Vitamin D ◽  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Sex Dependent Association of Vitamin D with Insulin Resistance

2021 ◽  
Author(s):  
Xin Chen ◽  
Chang Chu ◽  
Cornelia Doebis ◽  
Volker von Baehr ◽  
Berthold Hocher
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Animal Studies ◽  
Linear Regression Analysis ◽  
Cross Sectional Study ◽  
Multivariate Linear Regression Analysis ◽  
Double Blind ◽  
Cross Sectional ◽  
Entire Study

Abstract Background Animal studies suggested that vitamin D might decrease insulin resistance. Estrogen increased insulin sensitivity and glucose tolerance in rodents. However, sex-specific association of vitamin D with insulin resistance in humans remains unclear. Objectives To investigate the sex-dependency of the association of insulin resistance and 25(OH)D in a large Caucasian population. Methods Cross-sectional study from out-patients’ blood samples with measurements of 25(OH)D and HOMA-IR drawn at exactly the same day (N=1887). This cohort was divided into three groups: i) group with vitamin D deficiency (n=1190), ii) group with vitamin D sufficiency (N=686)), iii) vitamin D excess groups (n=11), the vitamin D excess group was excluded from further analysis due to the small size. Results Analysis of the entire study population showed that serum 25-hydroxyvitamin D was inversely associated with HOMA-IR (rs=-0.19, P<0.0001). When considering the vitamin D status, this association was only seen in the vitamin D deficiency group, but not in the vitamin D sufficient group. The correlation was sex-dependent: HOMA-IR was inversely correlated with vitamin D in women with vitamin D deficiency (rs=-0.26, P<0.0001) but not in men with vitamin D deficiency (rs=0.01, P=0.714). After multivariate linear regression analysis considering confounding factors, this relationship was again only seen in women. Conclusion Vitamin D was inversely and independently associated with insulin resistance only in women with vitamin D deficiency. Based on our data, we suggest that in particular vitamin D deficient women might benefit from vitamin D substitution by improving insulin resistance. This, however, needs to be proven in adequately designed double-blind placebo-controlled clinical studies.

scholarly journals To Determine The Frequency Of Vitamin D Deficiency In Patients With Chronic Hepatitis C

2018 ◽  
Vol 08 (04) ◽  
pp. 241-244
Author(s):  
Imran Hussain ◽  
M. Zill-e-Humayun Mirza ◽  
Ali Yusuf
Keyword(s):  
Vitamin D ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Vitamin D Deficiency ◽  
Chronic Hepatitis C ◽  
Cross Sectional Study ◽  
Blood Collection ◽  
Study Cohort ◽  
Sample Collection ◽  
Cross Sectional

Objective: To determine the frequency of vitamin D deficiency in patients with chronic hepatitis C (CHC) Design: It was a Descriptive and Cross Sectional study Place and Duration of Study: It was carried out in the Medicine Unit of Pakistan Naval Ship SHIFA, Karachi from Nov 29, 2016 to May 29, 2017. Patients and Methods: Approval was sought from Institutional Review Board before carrying out the study. Proper history, clinical examination and appropriate lab investigations were carried out. Standard techniques were used for blood sample collection. Site used for blood collection was antecubital fossa. Sterile method was used for fasting sample and about 10 ml of blood was collected from each patient. Results: A total of 289 patients were included. Strict exclusion and inclusion criteria was used for study cohort. Mean age (years) of study cohort was 34.51+8.32. There were 188 (65.1) male and 101 (34.9) female patients. Patients with CHC who were vitamin D deficient were 74 (25.6). Conclusion: Patients of CHC had high frequency of vitamin D deficiency which suggests that further studies in the region will be conduct in our general population to know the exact statistics which will pave the way for future researchers

scholarly journals Relationship Between Vitamin D Deficiency And Insulin Resistance In Obese Children

2020 ◽  
Vol 13 (1) ◽  
pp. 82
Author(s):  
Aidah Juliaty ◽  
Putri Lestari Gabrilasari ◽  
Dasril Daud ◽  
Johan Setyawan Lisal
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
Bivariate Analysis ◽  
Obese Children ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Deficiency Group

INTRODUCTION: Obesity represents the major risk factor for development of insulin resistance during childhood and adolescents. In obesity, adipose tissue release free fatty acids, various hormones, and cytokines, resulting in insulin resistance. This study aimed to establish the correlation between vitamin D deficiency and the incidence of insulin resistance in obese children. DESIGN AND METHOD: This analytical cross-sectional study was arranged from December 2019 - February 2020 included 96 students aged 11 - 17 years old from junior and senior high school who met the criteria for obesity in Makassar. The study subjects were parted into two groups, obese children with vitamin D deficiency (levels of 25-hydroxyvitamin D ≤ 20 ng/ml) and obese children without vitamin D deficiency group (levels of 25-hydroxyvitamin D > 20 ng/ml). Data were analyzed using univariate and bivariate analysis. RESULTS: The frequency of insulin resistance in obese children with vitamin D deficiency was 28 (54.9%), while obese children without vitamin D deficiency was 10 (22.2%). Based on statistical analysis, the frequency of the occurrence of insulin resistance in vitamin D deficiency obese children was higher than in obese children without vitamin D deficiency with OR = 4.261 (95% CI 1.744 – 10.411), p = 0.001. CONCLUSION: The risk of insulin resistance in obese children with vitamin D deficiency is 4.261 times higher than obese children without vitamin D deficiency.

scholarly journals Vitamin D Deficiency Is Common in Ghana despite Abundance of Sunlight: A Multicentre Comparative Cross-Sectional Study

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Samuel Asamoah Sakyi ◽  
Maxwell Hubert Antwi ◽  
Linda Ahenkorah Fondjo ◽  
Edwin Ferguson Laing ◽  
Richard K. Dadzie Ephraim ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Geographical Area ◽  
Daily Intake ◽  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

Background. Vitamin D is a steroid hormone important for the normal functioning of the body. It is produced through skin exposure to sunlight and from the diet. Although Ghana is located in the tropics where sunlight is abundant, factors like culture, diet, skin pigmentation, variation in the ozone layer, and geographical area influence the optimization of vitamin D concentration. It is imperative to evaluate the interplay between sunshine exposure, proinflammatory cytokines, and mediators of vitamin D metabolism and their relationship to vitamin D status in three geographical sections among apparent healthy Ghanaians. Methods and Results. In a cross-sectional study, a total of five hundred (500) healthy blood donors from three geographical areas in Ghana were enrolled. Their age ranged from 17 to 55 years with a mean age of 27.97 ± 8.87 years. The overall prevalence rate of vitamin D deficiency was 43.6% (218/500), with 41.2% (91/221), 45.3% (63/139), and 45.7% (64/140) of vitamin D deficiency being recorded in participants from the Northern Sector (NS), Middle Belt (MB), and Southern Sector (SS), respectively. However, there were no significant differences in the proportions of vitamin D deficiency across various geographical sectors. The median 25-hydroxyvitamin D serum levels were compared among geographical areas (NS, MB, and SS) and there were no significant differences ( P = 0.275 ) after adjusting for confounding factors. 25-Hydroxyvitamin D correlated positively with corrected ionized calcium (rs = 0.622, P ≤ 0.001 ) and phosphorus (rs = 0.299, P ≤ 0.001 ) and negatively correlated with SBP (rs = −0.092, P = 0.039 ), vitamin D binding protein (VDBP) (rs = −0.421, P ≤ 0.001 ), intact parathyroid hormone (iPTH) (rs = −0.0568, rs ≤ 0.001), IFN-gamma (rs = −0.684, P ≤ 0.001 ), and TNF-alpha (rs = −0.600, P ≤ 0.001 ). After adjusting for possible confounders, not having knowledge about vitamin D foods, taking fewer vitamin D foods, and higher levels of IF-γ and IL-10 were associated with a higher risk of having vitamin D deficiency. Conclusion. The prevalence of 25-hydroxyvitamin D deficiency is high among the general adult population in Ghana despite the abundance of sunlight. Increasing knowledge on vitamin D diet coupled with a daily intake of vitamin D dietary supplements is likely to reduce the risk of developing 25-hydroxyvitamin D deficiency.

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