scholarly journals Current Status of Otolaryngological Diseases among Paediatric Population Attending ENT OPD in Sylhet Women Medical College

2020 ◽  
Vol 8 (12) ◽  
pp. 2789-2792
Author(s):  
  Dr. Azadur Rahman ◽  
Dr. Nasrin Jahan ◽  
Dr. Tamanna Begum
2020 ◽  
Vol 54 (6) ◽  
pp. 1461-1472
Author(s):  
L. Horavova ◽  
K. Nebeska ◽  
L. Souckova ◽  
R. Demlova ◽  
P. Babula

Abstract Introduction Paediatric non-commercial interventional clinical trials (NICTs) are crucial for healthcare provision. In spite of the fact that current regulations and initiatives try to enhance the quantity and quality of paediatric NICTs, there are still shortcomings that need to be addressed in order to accelerate the conduct of relevant clinical trials in children. To improve the current landscape of paediatric clinical research, it is necessary to identify and analyse the main trends and shortcomings, along with their impact on national performance in paediatric NICTs and this is the aim of this work. Method A retrospective systematic search of paediatric NICTs was performed on four international clinical trials registries. Entries were filtered by date from 01/01/2004 to 31/12/2017. Each identified paediatric NICT was screened and analysed for sponsors, funders, type of intervention, therapeutic area, design characteristics and associated publications. Results The search identified 439 unique NICTs. When stratifying the trials by enrolment ages, 86 trials were found involving the paediatric population. Most trials investigated the use of medicinal products and were focused on cancer or cardiovascular diseases. The most common sources of the funding were non-profit organizations. Furthermore, from the total number of completed trials, only half of them already published their results. Conclusion The main shortcomings—specifically, ethical, methodological and, in particular, economic obstacles were identified. There is a continual need for greater support and collaboration between all major stakeholders including health policymakers, grant agencies, research institutions, pharmaceutical industries and healthcare providers at the national and international level.


2013 ◽  
Vol 2 (1) ◽  
pp. 9-14
Author(s):  
Md Hadiuzzaman ◽  
Muhammad Hasibur Rahman ◽  
Nahida Islam ◽  
Md Shahidul Islam ◽  
Sabrina Alam Mumu ◽  
...  

The spectra of the prevalence of skin diseases vary worldwide and from country to country. Therefore the information about the local prevalence of diseases is very important in helping the development of appropriate health improvement policies for promotion of better management. To document the types of skin disorders prevalent among rural children attending the Community Based Medical College Hospital out patient department, Mymensigh, a defined population based study was undertaken. The medical register from the Hospital was used to obtain information on pattern and outcome of skin diseases seen from January 2010 to December 2011. The frequency of pediatric dermatoses and their distribution patterns were studied. The results revealed that out of the 9279 Patients attending Dermatology out patient department of Community Based Medical College Hospital, 1753 (18.89%) Children were identified with involvement of skin diseases. Age range related to disease was found between one day old to 14 years. The most frequent skin condition was exposure to fungal diseases which was 25.67% followed by scabies 24.10% and eczema 20.25%. Infectious skin diseases represent considerably a high percentage of skin disorders encountered in pediatric population. DOI: http://dx.doi.org/10.3329/cbmj.v2i1.14175 Community Based Medical Journal Vol.2(1) 2013 9-14


Author(s):  
Ambrish Gupta ◽  
Prashant Maheshwari ◽  
Y. K. Rao

Background: The objective of current study was to analyse the pattern of adverse drug reactions due to different vaccines in paediatric patients.Methods: A prospective observational study was carried out in paediatric department of GSVM medical college Kanpur to monitor vaccine adverse event and its causal association with vaccine. Patients of 0-10 year age group of either sex, who developed adverse event following vaccination, were included in study. Vaccine adverse event were recorded in the suspected ADRs reporting form of Indian Pharmacopoeia commission. Causality was evaluated using WHO-UMC assessment scale, outcome and seriousness as per W.H.O. To classify type of ADRs, Expanded Rawlins- Thompson’s classification system was used.Results: Vaccine adverse reactions were more in female (53%) as compared to male (47%). Most common age group involved was 0-6 months; (79.41%) of total reactions. Fever (14.70 %) was most common reaction, followed by pain at inj. site (11.77%), and Convulsion (11.77). The causality of 67.65% vaccine adverse reactions was of possible type; 88.23 % reactions were of non-serious type. Type A reaction were more common and most of vaccine adverse reaction recovered (82.35%).Conclusions: Vaccines can also cause different types of adverse reactions in paediatric patients. This Study emphasizes the need for an effective vaccine adverse event monitoring system among paediatric patients in every hospital to ensure safety of vaccine. Hence more educational awareness program should be plotted and more similar studies are needed to be conducted.


Author(s):  
Anita Sanker ◽  
Sandhya George ◽  
Sindhu Chunangat Bhaskaramenon

<p class="abstract"><strong>Background:</strong> Leprosy is a chronic disease caused by <em>Mycobacterium leprae</em>, infectious in some cases, and affecting the peripheral nervous system, skin and certain other tissues. Even though leprosy was declared eliminated as a public health problem in India on December 2005, new cases of leprosy continue to appear. Hence a study on clinical profile and deformities in all leprosy cases registered in the last 5 years was done to know the current status of leprosy in this area.</p><p class="abstract"><strong>Methods: </strong>This was a retrospective record-based study of leprosy cases done at Government Medical College, Manjeri, for a period of 5 years from October 2014 to September 2019.<strong></strong></p><p class="abstract"><strong>Results:</strong> 42 cases from the record were included in the study. Maximum cases belonged to the age group of 31 to 40 and males were more than females. 81% of the patients were multibacillary leprosy (MB) and 8 cases belonged to paucibacillary (PB) leprosy. Four child cases were registered as PB cases. Mostly encountered clinical diagnosis was borderline tuberculoid leprosy (23 out of 42) and two had type 1 reaction. Seven patients had deformity of which two had grade 2 deformity and rest had grade 1 deformity.</p><p><strong>Conclusions:</strong> One patient who presented with grade 2 deformity and type 1 reaction was from tribal area indicating low awareness about leprosy among them. More number of cases in the multibacillary group and presence of child cases and deformities reinforces the need for strict surveillance to eradicate leprosy. </p>


2021 ◽  
Vol 20 (2) ◽  
pp. 8-13
Author(s):  
Maliha Ata ◽  
Rozina Hoque ◽  
Asma Mostafa ◽  
Md Rakibul I Shakil ◽  
Rajat Sanker Roy Biswas ◽  
...  

Background: In order to improve the spontaneous Adverse Drug Reaction (ADR) reporting practice by the physicians, there is an obligatory need to investigate the current situation of ADR reporting by them. The study was conducted to observe the ADR reporting pattern among physicians in a tertiary medical college hospital. Materials and methods: This was a descriptive cross sectional study carried out in a tertiary medical college hospital during the study period of March 2020 to October 2020. Data were collected from 100 physicians working on different departments using self designed pretested questionnaire by convenient sampling technique. Results: Among the 100 respondents 70 provided response to questionnaire giving a response rate 70%. Most of the respondents (61.43%) had adequate knowledge on ADR reporting. A good number of respondents showed positive attitude but there is no practice of ADR reporting though most of the respondents (84.3%) had experienced it in last 1 year. Most of the respondents experienced ADR with antibiotic (81.35%), NSAIDs (33.89%) & anticonvulsants (15.25%) and maximum (44.06%) experienced ADR was with skin, 30.50% with GIT and 23.03% with respiratory system involvement. The cause of under reporting was mainly due to inaccessible ADR form, busy schedule, unaware of how and whom to report and lack of motivation to report. The respondents would be encouraged to report ADR if they were provided with simple & available reporting form, regular guideline & bulletin. Conclusion: There is an urgent need for educational training & seminar regarding our national online reporting system to emphasizing ADR reporting. Chatt Maa Shi Hosp Med Coll J; Vol.20 (2); July 2021; Page 8-13


2010 ◽  
Vol 7 (2) ◽  
pp. 271-275 ◽  
Author(s):  
Gustavo F. Gonzales ◽  
José Aguilar ◽  
Martha Villar

The World Summit of Harmonization on Traditional, Alternative and Complementary Medicine (TACM) was held in Lima, Peru, November 7–11, 2007, with almost 600 worldwide participants. This meeting was organized by Peruvian Medical College, the institution that affiliates and authorizes all physicians to practice medicine in Peru. The meeting included seven sections starting with an overview on the current status of the TACM. The second section included experiences from different countries on regulations and quality control in products and services used in the TACM. The worldwide experience of education and training in TACM was a very important part of the meeting in which speakers from Spain, Germany, Argentina, Italy, Brazil, Cuba and Peru shared their experience. The meeting included topics on homeopathy, acupuncture, mind–body medicine, neural therapy, chiropraxis, among others. Two final sessions were related to the ways of linking Traditional medicine to the national Health Systems in the Latin America countries and also the association between bio-commerce and TACM including intellectual properties and bio-piracy.


1970 ◽  
Vol 18 (1) ◽  
pp. 37-43
Author(s):  
NC Saha ◽  
A Sultana ◽  
MAH Mollah ◽  
T Begum ◽  
AKMM Rahman ◽  
...  

Objectives: The objective of this study was to observe the outcome of patients treated with penicillamine. Design: Intervention type of study Setting: Department of Paediatrics, Dhaka Medical College Hospital Study period: January 2007 to December 2008. Study subjects: Sixteen diagnosed cases of Wilson's disease as per inclusion criteria. Intervention: D-penicillamine was started in a low dose, which was titrated gradually. The clinical and biochemical parameters were evaluated to look for the response to treatment. Results: A total of 16 cases were included. Among them 12 were male and 4 were female. The mean (± SD) of age of the patients was 10 (± 2.34) years. Consanguinity between parents was present in 44% (n=7). The hepatic and neurological variety of WD were 56 % (n=9) and 44% (n=7) respectively. The K-F ring was present in 75% (n=12/16) of WD cases. The excretion of 24 hrs urinary copper was steadily increased from discharge till second follow-up in response with increasing dose of penicillamine, thereafter the value was declining gradually till final follow-up at 1 year. Regarding outcome, 7 patients improved of which 4 were in hepatic and 3 in neurological group, 3 of hepatic WD expired and 2 developed neurological manifestations. One patients developed proteinuria while penicillamine treatment .About half of patients with WD were improved. Adequate cupriuresis occurred at three months. All the symptoms and biochemical markers WD improved gradually. No significant side effect was seen. Key words: Wilson's disease; penicillamine; urinary copper. DOI: 10.3329/jdmc.v18i1.6304 J Dhaka Med Coll. 2009; 18(1) : 37-43


2021 ◽  
Vol 9 (03) ◽  
pp. 605-606
Author(s):  
Srinivasan a ◽  
Prathap Kumar ◽  
Velladuraichi a ◽  
Ilaya Kumar ◽  
Sritharan b

Objectives: To evaluate the incidence, management, and outcome of visceral artery aneurysms (VAA) over the 5. years in our institution, a tertiary care centre, Madras Medical College. Methods 14 patients with 19 VAA were analysed according to location, diameter, aneurysm type, aetiology, rupture, management, and outcome. Results: VAA were localised at the splenic artery, coeliac trunk, renal artery, hepatic artery, superior mesenteric artery, and other locations. The aetiology was mostly degenerative, connective tissue disease. The rate of rupture was higher in pseudo-aneurysms than true aneurysms (66% vs 5%). 18 VAA were treated by intervention {coil embolisation} (n=3) or surgery (n=9) or hybrid [n=1] and one patient was managed conservatively. Three cases with ruptured VAA were treated on an emergency basis. The largest aneurysm was about 16cm and smallest one was about 1mm . After interventional treatment, the 30-day mortality was 21.4 % in ruptured VAA compared to no mortality in non-ruptured cases. Follow-up included USG and/or CT after a mean period of 7 months. The current status of the patient was obtained by a structured telephone survey. Conclusions: There is increase incidence of Celiac and SMA aneurysms. Aneurysm size seems to be a reliable predictor for rupture. Young patient need vasculitic workup for further management.


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