scholarly journals KARAKTERISASI PARAMETER SPESIFIK DAN PARAMETER NON SPESIFIK AKAR KUNING (Fibraurea tinctoria)

2020 ◽  
Vol 5 (2) ◽  
pp. 416-425
Author(s):  
Supomo Supomo ◽  
◽  
Hayatus Sa`adah ◽  
Eka Siswanto Syamsul ◽  
Kintoko Kintoko ◽  
...  
Keyword(s):  
Water Content ◽  
Ash Content ◽  
Water Soluble ◽  
Soluble Extract ◽  
Anticancer Properties ◽  
East Kalimantan ◽  
Extract Content ◽  
Water Soluble Extract ◽  
Cell Fragments

One of the secondary metabolites from yellow root (Fibraurea tinctoria) that has the potential to be developed as medicine is berberine. Alkaloid class compounds are reported to have antimicrobial, anti-diarrheal, intestinal parasite infection inhibitors, antihypertensives, anti-tumor, anti-inflammatory, hepatoprotective, antimalarial and anticancer properties. In the development of natural ingredients as medicine, it is necessary to standardize simplicia and extracts The research objective was to determine the characterization of specific and non-specific parameters of yellow root plants. This research is an experimental research. The object of research used yellow roots obtained from KDKT Samboja, Kutai Kartanegara district, East Kalimantan Province. Samples were made of simplicia which were extracted using the maceration method with 70% ethanol solvent. The results of the extraction were carried out by characterization including: macroscopic, microscopic, water content, water-soluble extract, ethanol-soluble extract, ash content, and acid-insoluble ash, then phytochemical screening was carried out. Data were analyzed using descriptive methods. The results of macroscopic characterization of yellow root simplicia powder were Liana with a length of 10-20 m, with round stems, bark grayish brown, coarse, 2-7 cm in diameter and bright yellow powder color. The simplicia powder microscopy found stone cell fragments and tracheal fragments. Characterization of simplicia powder, water content of 67.3%, ethanol soluble extract content of 6.69%, water soluble extract content of 8.05%, ash content of 7.37%, acid insoluble ash content of 0.37%. The results of the identification of the chemical compound group were positive for containing chemical compounds in the form of alkaloids, flavonoids and saponins.

scholarly journals Extraction And Phytochemical Screening of Ethanol Extract And Simplicia of Moringa Leaf (Moringa Oleifera Lam.) From Sidikalang, North Sumatera

2021 ◽  
Vol 2 (6) ◽  
pp. 2072-2076
Author(s):  
Ricky Andi Syahputra ◽  
Ani Sutiani ◽  
Pasar Maulim Silitonga ◽  
Zulmai Rani ◽  
Amelia Kudadiri
Keyword(s):  
Ethanol Extract ◽  
Ash Content ◽  
Water Soluble ◽  
Phytochemical Screening ◽  
Soluble Extract ◽  
Tropical Plant ◽  
Extract Content ◽  
Leaf Powder ◽  
Water Soluble Extract

Moringa leaf is a plant that has many uses that comes from the family Moringaceae and it is a tropical plant that is familiar to Indonesian people. Pharmacologically, this plant extract is reported to have antimicrobial and fungicide and it is rich in antioxidants. This metabolite compound contained in Moringa leaves has the potential as an antioxidant, antibacterial, functional and others. This study aims to determine the simplicia characterization of Moringa leaves and to determine the secondary metabolites contained in Moringa leaves, both Moringa leaf powder and Moringa leaf extract. The method of this research is experimental including the simplicia making and ethanol extract of Moringa leaves by maceration method, simplicia characterization and phytochemical screening. The results of the simplicia characterization of Moringa leaves for ethanol soluble extract content was 10,9% and water-soluble extract content was 15,8%, ash content was 9,6% and acid insoluble ash content was 0,6% and water content was 8%. The results of this study also showed that the simplicia powder and ethanol extract of Moringa leaves contained flavonoid, tannin, alkaloid, steroid and saponin.

scholarly journals Simplicia Characterization And Phytochemical Screening Of Secondary Metabolite Compounds Ethanol Extract Of Trembesi Leaves (Samanea saman)

2021 ◽  
Vol 12 (2) ◽  
pp. 131-140
Author(s):  
Zamharira Muslim ◽  
Heti Rais Khasanah ◽  
Yopita Sari
Keyword(s):  
Ethanol Extract ◽  
Ash Content ◽  
Water Soluble ◽  
Coarse Powder ◽  
Extract Content ◽  
Chemical Content ◽  
Water Soluble Extract ◽  
Samanea Saman ◽  
Descriptive Method

Trembesi plant (Samanea saman) is a plant that has the potential as traditional medicine. People in using medicinal plants often do not know the chemical content of these plants, so that in determining the amount of dosage, people only rely on experience and estimates. Research on the characterization of trembesi leaf simplicia has never been done. Research on the characterization of trembesi leaf simplicia has never been done. The purpose of this study was to determine the characteristics of trembesi leaf simplicia including specific and non-specific characteristics. The research is carried out in the form of experiments in the laboratory. The sample used is trembesi leaves. The research stages started from discovery, making simplicia, extraction, specific and non-specific characteristics. In the phytochemical test, ethanol extract of trembesi leaves was used. Data analysis used is descriptive method. Specific results showed trembesi leaf simplicia has a coarse powder form, distinctive odor, tasteless, green in color, and on microscopic results of trembesi leaf simplicia powder there is starch, fragments in the form of epidermis, water soluble extract content 11.93%, ethanol soluble essence 18, 93% and contains flavonoids, tannins, steroids and saponins. The results of non-specific characteristics are 8.07% water content, 7.91% ash content and 0.29% acid insoluble ash content.     

scholarly journals FORMULASI SEDIAAN KRIM ANTI LUKA BAKAR DARI EKSTRAK AIR DAGING DAUN ALOE VERA

Jurnal Kimia ◽  
2020 ◽  
pp. 37
Author(s):  
P. O. Samirana ◽  
N. W. Satriani ◽  
P. R. Harfa ◽  
S. P. P. Dewi ◽  
C. I. S. Arisanti
Keyword(s):  
Aloe Vera ◽  
Water Extract ◽  
Ash Content ◽  
Water Soluble ◽  
Soluble Extract ◽  
Meat Extract ◽  
Chemical Screening ◽  
Extract Content ◽  
Water Soluble Extract

Aloe vera (Aloe vera) is a plant that is empirically often used to heal burns. Aloe vera leaf meat water extract contains saponins and flavonoids, in addition it also contains tannins and polyphenols. This research was conducted to determine whether the extracted water of Aloe vera leaf meat had met the parameters of extract quality standards so that it could be used in formulations. The steps taken are the extraction of aloe vera leaf meat with the method of infundation maceration, standardization of Aloe vera meat water extraction including testing the determination of drying shrinkage, total ash content, determination of ash content which is insoluble in acid, determination of the essence of water soluble extract, determination of the extract soluble in ethanol and chemical screening, identification with FT-IR, preparation of cream preparations, evaluation of cream preparations. Aloe vera leaf meat extract was obtained by infudation technique. Tests for drying drying extract produced 26.33%, total ash content of 1.3%, water soluble extract content of 11.9% and ethanol soluble extract content of 12.01%, total flavonoid content of 2.9%.   Keywords: Aloe Vera, Formulation, Cream, Burns.

scholarly journals Standardization of Phyllanthus niruri and Sonchus arvensis as Components of Scientific Jamu

2020 ◽  
Vol 25 (1) ◽  
pp. 7
Author(s):  
Nikmatul Ikhrom Eka Jayani ◽  
Alfian Hendra Krisnawan ◽  
Nina Dewi Oktaviyanti ◽  
Kartini Kartini
Keyword(s):  
Ash Content ◽  
Water Soluble ◽  
Service Research ◽  
Soluble Extract ◽  
Phyllanthus Niruri ◽  
Standard Requirement ◽  
Extract Content ◽  
Crude Drugs ◽  
Water Soluble Extract ◽  
Sonchus Arvensis

Saintifikasi Jamu, or the scientific investigation of Jamu, is an evidence-based process to ensure the safety and efficacy of herbal medicine through health service research. Jamu has been empirically explored as a composition of various crude drugs, hence called as Scientific Jamu. Phyllanthus niruri and Sonchus arvensis are two of the 30 medicinal plants processed into Scientific Jamu. Components of the Scientific Jamu are standardized to ensure that these materials meet the predefined quality. This study was aimed to determine the specific parameters (macroscopic, microscopic, total flavonoid content, water-soluble extract content, and ethanol-soluble extract content) and non-specific parameters (loss on drying, total ash content, and acid insoluble ash content) of Phyllanthus niruri and Sonchus arvensis collected from Batu, Tawangmangu, and Bogor. The methods of the determination referred to the Indonesian Herbal Pharmacopoeia 1st Edition (2008). The results showed that Phyllanthus niruri and Sonchus arvensis from the three places did not meet the standard requirement.

scholarly journals Standardization of Simplicia and Ethanol Extract of Purun Danau (Lepironia articulata (Retz.) Domin) Rhizome

2021 ◽  
Vol 4 (4) ◽  
pp. 273-282
Author(s):  
Arnida Arnida ◽  
Maulidia Maulidia ◽  
Amalia Khairunnisa ◽  
Sutomo Sutomo ◽  
Faisal Faisal
Keyword(s):  
Drying Shrinkage ◽  
Ethanol Extract ◽  
Ash Content ◽  
Water Soluble ◽  
Soluble Extract ◽  
Extract Content ◽  
Standard Parameter ◽  
Water Soluble Extract ◽  
Specific Odor ◽  
General Standard

Purun Danau (Lepironia articulata (Retz.) Domin) has been shown to have antimalarial and antioxidant activity. This study aimed to standardize simplicia and extract of L. articulata by determining the value of its specific and non-specific parameters. A sampling of L. articulata rhizome was carried out in Guntung Manggis, Haur Gading, and Halat. The standardization method used was based on the Indonesian Herbal Pharmacopoeia and the General Standard Parameter of Extract. The organoleptic observations showed that L. articulata simplicia was reddish-brown in color, chelated taste, and had a specific odor. Microscopic observation showed parts of this plant: epidermis, cortex, endodermis, parenchyma, bundle vessels, and scalariform vessels. Ethanol-soluble extract content was 10.00-12.66%, water-soluble extract content 8.03-10.87%, drying shrinkage 7.10-7.33%, total ash content 2.03-2.52%, acid-insoluble ash 0.33-0.42%, Pb content 5.698-9.989 ppm, Cd content 0.300-0.500 ppm, Hg content 0.070-0.090 ppm. Ethanol extract of L. articulata rhizome contained alkaloids, flavonoids, tannins, glycosides, and saponins. The yield obtained was 8.05-11.23%, total ash content was 1.58-1.67%, acid-insoluble ash was 0.23-0.33%, and water content was 7.10-8.50%. Standardization of simplicia and ethanol extract of L. articulata rhizome has met the criteria.

scholarly journals Pharmacognostic Study and Antioxidant Activity of Mundar (Garcinia forbesii King.) leaves from Banua Botanical Gardens of South Kalimantan

2020 ◽  
Vol 3 (4) ◽  
pp. 209-215
Author(s):  
Sutomo Sutomo ◽  
Dina Noor Kamali ◽  
Arnida Arnida ◽  
Normaidah Normaidah ◽  
Agung Sriyono
Keyword(s):  
Antioxidant Activity ◽  
Drying Shrinkage ◽  
Ethanol Extract ◽  
Ash Content ◽  
Water Soluble ◽  
Soluble Extract ◽  
Extract Content ◽  
Dpph Method ◽  
Specific Parameter ◽  
Parameter Test

Mundar (Garcinia forbesii King.) is a plant from South Kalimantan. This plant has chemical contents that have potential as medicine. The purpose of this study is to provide a pharmacognostic picture of a specific, nonspecific and determine the antioxidant activity of G. forbesii leaves. Specific parameters include organoleptic, microscopic testing, thin-layer chromatography profiles, and phytochemical screening. Nonspecific parameters include total ash content, acid insoluble ash content, drying loss, water-soluble extract content, and ethanol-soluble extract content. Antioxidant activity was determined by the DPPH method based on IC50 values. Specific parameter test results are green powder, characteristic odor, and sour taste. Microscopic tests showed stomata, upper epidermis, lower epidermis, cell walls, xylem, phloem, palisade tissue, spongy tissue, and cuticles. Garcinia forbesii leaves contain alkaloids, flavonoids, phenols, tannins, and steroids. The TLC profile showed good separation of polar eluents, and yellow spots appeared after spraying DPPH reagents. The non-specific parameter test is the total ash content of 6.52�0.1%; acid insoluble ash content 1.06�0.08%; drying shrinkage 6.43�0.38%; water-soluble extracts 34.3�0.3%; and ethanol-soluble extracts 23.47�0.35%. Ethanol extract of G. forbesii leaves has antioxidant activity with IC50 of 65.7 ppm. Pharmacognostic study fulfills the requirements, and G. forbesii leaves extract has strong antioxidant activity.

scholarly journals Karakterisasi Simplisia dan Uji Aktivitas Antioksidan Ekstrak dan Fraksi Daun Pidada Merah (Sonneratia caseolaris L)

KOVALEN ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. 184-190
Author(s):  
Eka Siswanto Syamsul ◽  
Supomo ◽  
Siti Jubaidah
Keyword(s):  
Antioxidant Activity ◽  
Ethanol Extract ◽  
Ethyl Acetate Fraction ◽  
Ash Content ◽  
Water Soluble ◽  
Soluble Extract ◽  
Leaf Extracts ◽  
Mangrove Plant ◽  
Sonneratia Caseolaris ◽  
Extract Content

Research on red Pidada leaves (Sonneratia caseolaris L.) which is a mangrove plant with antioxidant potential has been carried out. This study aims to determine the simplicia characterization and activity of red Pidada leaf extracts and fractions as antioxidants. The results of the simplicia characterization were: water-soluble extract content of 11%, ethanol-soluble extract content of 16%, water content of 9%, ash content of 8.17%, and acid insoluble ash content of 0.48%. The antioxidant activity test was carried out using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The antioxidant activity was determined by the IC50 (Inhibition Concentration) value. The results showed that the ethanol extract had an IC50 value of 24.22 ppm (very strong), n-hexane fraction 88.18 ppm (strong), ethyl acetate fraction 15.39 ppm (very strong), and ethanol fraction 38.41 ppm (very strong) Keywords: Sonneratia caseolaris L., antioxidants, DPPH, IC50

scholarly journals The brewing conditions optimization of Eucalyptus blended tea bags

2021 ◽  
Vol 924 (1) ◽  
pp. 012063
Author(s):  
M F F Mu’tamar ◽  
M Fakhry ◽  
M Ulya
Keyword(s):  
Black Tea ◽  
Water Soluble ◽  
Soluble Extract ◽  
Overall Acceptability ◽  
Extract Content ◽  
Two Factors ◽  
Herbal Plants ◽  
Water Soluble Extract ◽  
Central Composite ◽  
Brewing Time

Abstract Blended tea is a mixed herbal drink made from herbal plants’ leaves, roots, flowers, or stems. The blended tea that formulation has been reported in previous studies is composed of Eucalyptus leaves, cinnamon, and black tea. However, the optimum brewing conditions of Eucalyptus blended tea have not been studied. This study aims to determine the optimum brewing conditions of Eucalyptus blended tea using Response Surface Methodology (RSM) with Central Composite Design (CCD). This study used two factors, the loading per tea bag (2 g, 2.5 g, 3 g) and brewing time (2, 4, and 6 minutes). The parameters used were water-soluble extract content, color (L, a, b), and overall acceptability. The results showed that a weight of 2.48 g with a brewing time of 3.45 minutes was the optimum condition for brewing blended tea of Eucalyptus, cinnamon, and black tea.

Standardisasi Simplisia dan Ekstrak Daun Matoa (Pometia pinnata J.R Forst & G. Forst) Asal Kalimantan Selatan

2021 ◽  
Vol 8 (1) ◽  
pp. 101
Author(s):  
Sutomo Sutomo ◽  
Norijatil Hasanah ◽  
Arnida Arnida ◽  
Agung Sriyono
Keyword(s):  
Bitter Taste ◽  
Botanical Garden ◽  
Ash Content ◽  
Water Soluble ◽  
Cell Nuclei ◽  
Soluble Extract ◽  
Green Color ◽  
Medicinal Plant Extracts ◽  
Water Soluble Extract ◽  
Ethanol Extracts

Matoa (Pometia pinnata) merupakan salah satu  tumbuhan yang dapat tumbuh dengan baik di Kalimatan dan diketahui mengandung metabolit sekunder yang berpotensi sebagai obat. Penelitian ini bertujuan untuk melakukan standardisasi berdasarkan parameter spesifik dan nonspesifik dari simplisia dan ekstrak. Pengambilan sampel daun P. pinnata dilakukan pada tiga tempat tumbuh yaitu Desa Pemuda, Kebun Raya Banua, dan Tahura Sultan Adam. Metode standardisasi yang digunakan mengacu pada Farmakope Herbal Indonesia dan Parameter Standar Umum Ekstrak. Pengamatan organoleptik simplisia yaitu berwarna hijau muda, rasa pahit, berbau khas. Pengamatan mikroskopik menunjukkan adanya dinding sel, floem, xilem, stomata, dan inti sel. Kadar sari larut etanol (19,07-19,27)%; kadar sari larut air (20,93-21,17)%; susut pengeringan (6,17-6,23)%; kadar abu total (4,63-4,73)%; kadar Pb (0,014-0,022) ppm; kadar Cd (0,014-0,015)ppm; dan kadar Hg <0,00004ppm. Pemerian ekstrak yaitu berwarna hijau kehitaman, berbau khas, rasa pahit. Ekstrak etanol daun P. pinnata mengandung alkaloid, flavonoid, steroid, tanin, glikosida, saponin, antrakuinon yang ditegaskan pada profil KLT menunjukkan kesamaan kandungan senyawa kimia pada tiap tempat tumbuh. Rendemen yang didapat (11,19-14,68)%; kadar air (5,57-5,97)%; kadar abu total (1,19-1,24)%; dan kadar abu tidak larut asam (0,41-0,44)%. Hasil uji parameter spesifik dan nonspesifik simplisia dan ekstrak daun P. pinnata dari tiga tempat tumbuh telah memenuhi syarat yang ditetapkan oleh MMI dan BPOM RI. Kata Kunci :  Standardisasi; Matoa; Pometia pinnata, Simplisia; Ekstrak   Matoa (Pometia pinnata) is one of the plants that can grow well in Kalimantan and known to contain efficacious secondary metabolites. This study is aimed to determine the value of specific parameters and nonspecific parameters of simplicia and extract. The leaves of P. pinnata was carried out in three growing places, which are the Pemuda Village, Banua Botanical Garden, and Tahura Sultan Adam. The method of determining the standardization parameters refers to Indonesian Herbal Pharmacopoeia and the General Standard Parameters of Medicinal Plant Extracts. The result from organoleptic observations of simplicia showed that P. pinnata had a light green color, a bitter taste, and a distinctive smell. Microscopic observations showed phloem, xylem, stomata, cell nuclei, cell walls. The content of ethanol soluble extract was 19.07%-19.27%, water soluble extract content was 20.93%-21.17%, drying losses was 6.17%-6.23%, total ash content was 4.63%-4.73%, Pb levels was 0.014-0.022ppm, Cd levels was 0.014-0.015ppm, and Hg levels was <0.00004 ppm. The description of extracts was that P. pinnata had a blackish green color, a bitter taste, and a distinctive smell. Ethanol extracts of P. pinnata leaves contained alkaloids, flavonoids, steroids, tannins, glycosides, saponins, anthraquinones which were confirmed in the TLC profile  showing the similarity of chemical compounds in each growing place. The yield extract was 11.19%-14.68%, water content was 5.57%-5.97%, total ash content was 1.19%-1.24%, and acid insoluble ash content was 0.41%-0.44%. The results of specific and nonspecific parameters of simplicia and P. pinnata leaf extract from three growing sites have met the requirements set by MMI and BPOM RI.

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