scholarly journals Computer-aided diagnosis of lung malignity using multidimensional analysis of tumour marker data

2021 ◽  
Vol 8 (1) ◽  
pp. 65-70
Author(s):  
Viera Mrázová ◽  
Ján Mocák ◽  
Elena Varmusová ◽  
Denisa Kavková

The aim of this work is assessing diagnostic performance of lung tumour markers. Three clinical laboratory tests were used for indicating lung malignancy in order to verify or predict the patient’s diagnosis. The data set of 182 patients was examined and two main groups of the patient samples were created – 86 with diagnosed malignancy (confirmed by histology) and 96 with diagnosed benign tumours or tuberculosis. The following tumour markers were analyzed: carcinoembryonic antigen and cytokeratin 19 fragment, which were sampled in the pleural exudates, and the same tumour markers in serum. In addition, the patient’s age and the gender of the corresponding individual were used as further variables in the original data matrix. Three laboratory tests were used for indicating lung malignancy in order to verify or predict the patient’s diagnosis not only by using the results of the chosen individual laboratory test but also applying multivariate statistical approach, which jointly utilizes all performed tests in the form of their optimal linear combination.

1994 ◽  
Vol 144 ◽  
pp. 139-141 ◽  
Author(s):  
J. Rybák ◽  
V. Rušin ◽  
M. Rybanský

AbstractFe XIV 530.3 nm coronal emission line observations have been used for the estimation of the green solar corona rotation. A homogeneous data set, created from measurements of the world-wide coronagraphic network, has been examined with a help of correlation analysis to reveal the averaged synodic rotation period as a function of latitude and time over the epoch from 1947 to 1991.The values of the synodic rotation period obtained for this epoch for the whole range of latitudes and a latitude band ±30° are 27.52±0.12 days and 26.95±0.21 days, resp. A differential rotation of green solar corona, with local period maxima around ±60° and minimum of the rotation period at the equator, was confirmed. No clear cyclic variation of the rotation has been found for examinated epoch but some monotonic trends for some time intervals are presented.A detailed investigation of the original data and their correlation functions has shown that an existence of sufficiently reliable tracers is not evident for the whole set of examinated data. This should be taken into account in future more precise estimations of the green corona rotation period.


Author(s):  
Wendy J. Schiller ◽  
Charles Stewart III

From 1789 to 1913, U.S. senators were not directly elected by the people—instead the Constitution mandated that they be chosen by state legislators. This radically changed in 1913, when the Seventeenth Amendment to the Constitution was ratified, giving the public a direct vote. This book investigates the electoral connections among constituents, state legislators, political parties, and U.S. senators during the age of indirect elections. The book finds that even though parties controlled the partisan affiliation of the winning candidate for Senate, they had much less control over the universe of candidates who competed for votes in Senate elections and the parties did not always succeed in resolving internal conflict among their rank and file. Party politics, money, and personal ambition dominated the election process, in a system originally designed to insulate the Senate from public pressure. The book uses an original data set of all the roll call votes cast by state legislators for U.S. senators from 1871 to 1913 and all state legislators who served during this time. Newspaper and biographical accounts uncover vivid stories of the political maneuvering, corruption, and partisanship—played out by elite political actors, from elected officials, to party machine bosses, to wealthy business owners—that dominated the indirect Senate elections process. The book raises important questions about the effectiveness of Constitutional reforms, such as the Seventeenth Amendment, that promised to produce a more responsive and accountable government.


2020 ◽  
Author(s):  
Eva Østergaard-Nielsen ◽  
Stefano Camatarri

Abstract The role orientation of political representatives and candidates is a longstanding concern in studies of democratic representation. The growing trend in countries to allow citizens abroad to candidate in homeland elections from afar provides an interesting opportunity for understanding how international mobility and context influences ideas of representation among these emigrant candidates. In public debates, emigrant candidates are often portrayed as delegates of the emigrant constituencies. However, drawing on the paradigmatic case of Italy and an original data set comprising emigrant candidates, we show that the perceptions of styles of representation abroad are more complex. Systemic differences between electoral districts at home and abroad are relevant for explaining why and how candidates develop a trustee or delegate orientation.


2021 ◽  
pp. 245513332110316
Author(s):  
Tiken Das ◽  
Pradyut Guha ◽  
Diganta Das

This study made an attempt to answer the question: Do the heterogeneous determinants of repayment affect the borrowers of diverse credit sources differently? The study is based on data collected from 240 households from three districts in the lower Brahmaputra valley of Assam through a carefully designed primary survey. Besides, the study uses the double hurdle approach and the instrumental variable probit model to reduce possible selection bias. It observes better repayment performance among formal borrowers, followed by semiformal borrowers, while occupation wise it is prominent among organised employees. It has been found that in general, the household characteristics, loan characteristics and location-specific characteristics significantly affect repayment performance of borrowers. However, the nature of impact of the factors influencing repayment performance is remarkably different across credit sources. It ignores the role of traditional community-based organisations in rural Assam while analysing the determinants of repayment performance. The study also recommends for ensuring productive opportunities and efficient market linkages in rural areas of Assam. The study is based on an original data set that has specially been collected to examine question that—do the heterogeneous determinants of repayment affect the borrowers of diverse credit sources differently in the lower Brahmaputra valley of Assam—which has not been studied before.


2021 ◽  
Vol 11 (5) ◽  
pp. 2166
Author(s):  
Van Bui ◽  
Tung Lam Pham ◽  
Huy Nguyen ◽  
Yeong Min Jang

In the last decade, predictive maintenance has attracted a lot of attention in industrial factories because of its wide use of the Internet of Things and artificial intelligence algorithms for data management. However, in the early phases where the abnormal and faulty machines rarely appeared in factories, there were limited sets of machine fault samples. With limited fault samples, it is difficult to perform a training process for fault classification due to the imbalance of input data. Therefore, data augmentation was required to increase the accuracy of the learning model. However, there were limited methods to generate and evaluate the data applied for data analysis. In this paper, we introduce a method of using the generative adversarial network as the fault signal augmentation method to enrich the dataset. The enhanced data set could increase the accuracy of the machine fault detection model in the training process. We also performed fault detection using a variety of preprocessing approaches and classified the models to evaluate the similarities between the generated data and authentic data. The generated fault data has high similarity with the original data and it significantly improves the accuracy of the model. The accuracy of fault machine detection reaches 99.41% with 20% original fault machine data set and 93.1% with 0% original fault machine data set (only use generate data only). Based on this, we concluded that the generated data could be used to mix with original data and improve the model performance.


2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Maria Schiller ◽  
Christine Lang ◽  
Karen Schönwälder ◽  
Michalis Moutselos

AbstractIn both Germany and France, perceptions of immigration, diversity and their societal consequences have undergone important transformations in the past two decades. However, existing research has only partially captured such processes. The “grand narratives” of national approaches, while still influential, no longer explain contemporary realities. Further, analyses of national politics and discourses may not sufficiently reflect the realities across localities and society more broadly. While emerging in different national contexts, little is known about how diversity is actually perceived by political stakeholders at the urban level. Given the key role of immigration and diversity in current conflicts over Europe’s future, it is imperative to assess present-day conceptualisations of migration-related diversity among important societal actors.This article investigates perceptions and evaluations of socio-cultural heterogeneity by important societal actors in large cities. We contribute to existing literature by capturing an unusually broad set of actors from state and civil society. We also present data drawn from an unusually large number of cities. How influential is the perception of current society as heterogeneous, and what forms of heterogeneity are salient? And is socio-cultural and migration-related heterogeneity evaluated as threatening or rather as beneficial? Based on an original data set, this study explores the shared and contested ideas, the cognitive roadmaps of state and non-state actors involved in local politics.We argue that, in both German and French cities, socio-cultural heterogeneity is nowadays widely recognized as marking cities and often positively connoted. At the same time, perceptions of the main features of diversity and of the benefits and challenges attached to it vary. We find commonalities between French and German local actors, but also clear differences. In concluding, we suggest how and why national contexts importantly shape evaluations of diversity.


1987 ◽  
Vol 65 (3) ◽  
pp. 691-707 ◽  
Author(s):  
A. F. L. Nemec ◽  
R. O. Brinkhurst

A data matrix of 23 generic or subgeneric taxa versus 24 characters and a shorter matrix of 15 characters were analyzed by means of ordination, cluster analyses, parsimony, and compatibility methods (the last two of which are phylogenetic tree reconstruction methods) and the results were compared inter alia and with traditional methods. Various measures of fit for evaluating the parsimony methods were employed. There were few compatible characters in the data set, and much homoplasy, but most analyses separated a group based on Stylaria from the rest of the family, which could then be separated into four groups, recognized here for the first time as tribes (Naidini, Derini, Pristinini, and Chaetogastrini). There was less consistency of results within these groups. Modern methods produced results that do not conflict with traditional groupings. The Jaccard coefficient minimizes the significance of symplesiomorphy and complete linkage avoids chaining effects and corresponds to actual similarities, unlike single or average linkage methods, respectively. Ordination complements cluster analysis. The Wagner parsimony method was superior to the less flexible Camin–Sokal approach and produced better measure of fit statistics. All of the aforementioned methods contain areas susceptible to subjective decisions but, nevertheless, they lead to a complete disclosure of both the methods used and the assumptions made, and facilitate objective hypothesis testing rather than the presentation of conflicting phylogenies based on the different, undisclosed premises of manual approaches.


2004 ◽  
Vol 34 (1) ◽  
pp. 37-52
Author(s):  
Wiktor Jassem ◽  
Waldemar Grygiel

The mid-frequencies and bandwidths of formants 1–5 were measured at targets, at plus 0.01 s and at minus 0.01 s off the targets of vowels in a 100-word list read by five male and five female speakers, for a total of 3390 10-variable spectrum specifications. Each of the six Polish vowel phonemes was represented approximately the same number of times. The 3390* 10 original-data matrix was processed by probabilistic neural networks to produce a classification of the spectra with respect to (a) vowel phoneme, (b) identity of the speaker, and (c) speaker gender. For (a) and (b), networks with added input information from another independent variable were also used, as well as matrices of the numerical data appropriately normalized. Mean scores for classification with respect to phonemes in a multi-speaker design in the testing sets were around 95%, and mean speaker-dependent scores for the phonemes varied between 86% and 100%, with two speakers scoring 100% correct. The individual voices were identified between 95% and 96% of the time, and classifications of the spectra for speaker gender were practically 100% correct.


PEDIATRICS ◽  
1952 ◽  
Vol 10 (3) ◽  
pp. 311-318
Author(s):  
WILLIAM J. WATERS ◽  
SEYMOUR S. KALTER ◽  
JOHN T. PRIOR

The clinical, laboratory and pathologic findings of a series of cases of cat scratch syndrome have been reviewed. In spite of a variable clinical course, certain features associated with a selected group of laboratory tests appear to be constant enough to be of diagnostic value. A history of contact with a cat and/or scratch which is usually associated with a peripheral skin lesion, lack of lymphangitis, presence of regional lymphadenopathy with tenderness to palpation are the most constant clinical findings. Fever, so frequently emphasized as a characteristic clinical sign, may be extremely variable in type and duration or entirely absent. A skin test with cat scratch antigen has been positive in all cases. Lacking this antigen, a negative Frei skin test in conjunction with a positive complement fixation test (Lygranum C. F.) is suggestive evidence for the diagnosis. With positive evidence from the above data, biopsy of an affected gland with its relatively nonspecific pathologic picture is not considered essential for the establishment of the diagnosis of cat scratch syndrome.


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