scholarly journals Difficulties in diagnosing multiple myeloma with lung damage

Author(s):  
I. V. Demko ◽  
M. G. Mamaeva ◽  
A. Yu. Kraposhina ◽  
I. A. Solovieva ◽  
N. V. Gordeeva ◽  
...  

Multiple myeloma occupies a leading position among malignant blood diseases. There is clinical evidence that multiple myeloma can be complicated by secondary amyloidosis. The article presents a clinical case for the diagnosis of multiple myeloma complicated by secondary pulmonary amyloidosis. The participation of doctors of various specialties (pulmonologist, hematologist, pathologist), the use of high-tech diagnostic methods (histological examination of a biopsy of lung tissue, trepanobiopsy, immunohistochemical examination of histological preparations of lungs and bone marrow), made it possible to establish a clinical diagnosis. 

2021 ◽  
Vol 5 (6) ◽  
pp. 433-437
Author(s):  
T.E. Skvortsova ◽  
◽  
I.A. Oganezova ◽  
O.I. Medvedeva ◽  
O.M. Zhorina ◽  
...  

Gastrointestinal stromal tumors (GIST) are the most common malignant submucosal neoplasms of the gastrointestinal tract, with predominant localization in the stomach and small intestine. The disease pattern is the absence of specific clinical signs, at least a third of cases are detected during examinations or surgical interventions for other diseases or at an autopsy. The examination algorithm of patients with suspected GIST includes endoscopic and radiation diagnostic methods, including a number of high-tech and expensive techniques, such as endoscopic ultrasonography, computed tomography, immunohistochemical and molecular genetic methods for studying biopsy material. Only conducting a full set of examinations will allow timely diagnosis and choosing the optimal treatment tactics for the disease with a high risk of malignancy. The authors present their own clinical case of a patient, female, with GIST, which is of considerable interest to clinicians. The above clinical case represents a typical clinical and morphological picture of GIST. The disease onset occurred in a patient over the age of 60 years and proceeded under the guise of organic dyspepsia. In this case, the use of expensive high-tech techniques allowed to verify the diagnosis of GIST and refer the patient to surgical treatment. KEYWORDS: gastrointestinal stromal tumor, stomach tumor, endoscopic ultrasonography, immunohistochemistry, differential diagnosis. FOR CITATION: Skvortsova T.E., Oganezova I.A., Medvedeva O.I. et al. Gastrointestinal stromal tumor of the stomach (clinical case). Russian Medical Inquiry. 2021;5(6):433–437 (in Russ.). DOI: 10.32364/2587-6821-2021-5-6-433-437.


2019 ◽  
Vol 2019 (4) ◽  
pp. 26-29
Author(s):  
Владислава Илларионова ◽  
Vladislava Illarionova

Tumors of the heart are a rare and, until recently, poorly studied pathology in humans and animals. Currently, the frequency of intravital detection of heart tumors and their successful treatment is increasing due to the use of high-tech diagnostic methods, such as echocardiography, computed tomography and magnetic resonance imaging, myocardial biopsy with histological and immunohistochemical examination of the tumor. However, in some cases, even the use of a wide range of diagnostic capabilities of intravital diagnostics does not provide sufficient data and confirmation of the diagnosis is possible only by the results of postmortem autopsy. The clinical manifestations of tumor growth in the heart are variable and depend on the type of tumor and its location. The most common primary neoplasm of the heart is hemangiosarcoma, the second most frequent tumor is the base of the heart tumor - nonchromophinous paraganglioma (chemodectoma). Our clinical case indicates possible difficulties in the diagnosing of heart base tumors, even with the use of a wide range of high-tech diagnostic methods.


2019 ◽  
Vol 1 (9) ◽  
pp. 53-57
Author(s):  
T. N. Gavva ◽  
L. V. Kuzmenkova ◽  
Yu. N. Fedulaev ◽  
T. V. Pinchuk ◽  
D. D. Kaminer ◽  
...  

A case of lung damage in systemic lupus erythematosus (SLE) in a 33-year-old woman is described. This case is of clinical interest due to the complexity of diagnosis due to the fact that SLE is a disease with diverse clinical manifestations involving many organs and systems, which often makes it difficult to timely recognize the onset of the disease. SLE still remains a challenge and requires special attention to the patient s history, clinical and laboratory parameters of the patient, as well as specific immunological examinations.


Author(s):  
A.O. Nazarenko ◽  
◽  
E.E. Sidorenko ◽  
D.V. Miguel ◽  
A.S. Smartsev ◽  
...  

A clinical case of observation of a 3-year-old child with a newly diagnosed optic nerve coloboma and multiple malformations is considered. The clinical picture and diagnostic methods necessary for the diagnosis are reflected. On the example of this child, the differential diagnosis with Charge syndrome is considered. Key words: coloboma, optic nerve coloboma, partial optic nerve atrophy, astigmatism, Charge syndrome.


Author(s):  
N.R. Sharvadze ◽  
◽  
A.L. Shtilerman ◽  
D.P. Skachkov ◽  
Y.A. Drovnyak ◽  
...  

In the article are presented analytical review of scientific articles devoted to the study of modern methods of diagnostics of primary glaucoma. On the basis of scientific articles, a review material was collected and systematized on diagnostic methods for studying morphometric and functional changes in primary glaucoma, which are used in modern ophthalmic practice. In recent years, the improvement and implementation of new high-tech modern diagnostic methods open up new opportunities for researchers and clinicians. Optical coherence tomography, OCT angiography, static perimetry make it possible, by comparing morphometric and functional parameters, to give a more complete, comprehensive assessment of pathological changes in the optic nerve head, in the macular region and at the level of the choriocapillaries. Prevention of glaucoma blindness largely depends on its early diagnosis based on the use of modern organizational and medical technologies. Key words: glaucoma, open-angle glaucoma, intraocular pressure, glaucomatous optic neuropathy, diagnostic methods.


Author(s):  
М. П. Самоховец ◽  
Е. А. Гречишкина

The study of mutual trade of the EAEU member states is relevant from the point of view of its improvement in order to achieve the macroeconomic effect of the EAEU creation. The purpose of the article is to study the economic indicators of mutual trade between the EAEU member states and to identify the main trends and prospects for trade relations development in the EAEU integration environment. The object of the study is trade relations between the EAEU member states. Methods used in the study. The study was conducted using official statistics of the EAEU for 2014–2018 and is based on economic comparisons and systematization. The development of cooperative ties within the EAEU, an extensive list of program and reporting documents was studied. Research hypothesis. Mutual trade of the EAEU member states has positive development trends. Statement of the main material. Significant changes in the dynamics of trade relations and their regulation in Belarus, Russia, Kazakhstan, Kyrgyzstan, Armenia are associated with the creation of the EAEU. The analysis of indicators of mutual trade between the EAEU member states showed that the Russian Federation occupies a leading position in mutual trade, and the Russian market is main market for goods from other EAEU member states. Trends indicate that the benefits of integration within the EAEU are not fully realized. Originality and practical value. Further development of EAEU trade relations is seen in the context of regional economic integration. Development on a cooperative basis will save the costs of the EAEU member countries and take advantage of the specialization of the countries. Conclusion. Intensification of mutual trade of the EAEU member states is possible by stimulating consumer and industrial demand, increasing the export of high-tech products and diversifying exports


2017 ◽  
Vol 4 (2) ◽  
pp. 65-71
Author(s):  
Oleksandra Slobodianiuk

Slobodianiuk O.L.In recent years much attention has been paid to the upper digestive tract diseases in children, particularly GERD, as a reason t,hat has an impact on quality of life even in children of school age and thereafter in young adults. Scientists came to a consensus that all examinations which are used in pediatric practice must be maximally available, simple and non-invasive to the extent practical for child’s condition.The question about practicability of performing esophagogastroduodenoscopy for all patients with complaints of heartburn and with other symptoms of GERD, the question relative to performing ultrasonography of the esophagus for children as an additional method of examination, usage of questionnaire in pediatric practice, formation of disease course prediction algorithm, and identification of preventive measures specific to every patient remain open.Therefore the goal of this research is to provide an overview of modern literature with reference to problematic issues of clinical evidence, risk factors, diagnostics, prediction of gastroesophageal reflux disease course in children of different age (regarding main causative and pathogenic factors, clinical evidence (esophageal and extra-esophageal), diagnostic methods and modern approaches to gastroesophageal reflux disease treatment).Key words: gastroesophageal reflux disease, non-invasive diagnostics, risk factors, prediction of disease course. СУЧАСНІ ПОГЛЯДИ НА ГЕРХ У ДІТЕЙ: ПРОБЛЕМИ ТА ПЕРСПЕКТИВИСлободянюк О.Л.Останнім часом багато уваги приділяється захворюванням верхніх відділів травного тракту у дітей, зокрема й ГЕРХ,  як причині, що призводить до порушення якості життя вже у дітей шкільного віку, а в подальшому і у людей молодого віку. Вчені дійшли консенсусу, що всі обстеження, які використовуються в педіатричній практиці повинні бути максимально доступними, простими та неінвазивними, наскільки це дозволяє стан дитини.Залишається відкритим питання про доцільність проведення ФЕГДС всім пацієнтам зі скаргами на печію та іншими симптомами ГЕРХ , питання щодо застосування УЗД стравоходу у дітей як додаткового методу обстеження, використання опитувальників в педіатричній практиці, формування алгоритмів прогнозування перебігу захворювання та визначення профілактичних заходів  індивідуально для кожного пацієнта.Отже, метою цієї роботи було виконати огляд сучасної літератури з проблемних питань клінічних проявів, факторів ризику, діагностики, прогнозування перебігу гастроезофагеальної рефлексної хвороби у дітей різного віку (з питань основних етіологічних та патогенетичних факторів, клінічних проявів (стравохідних та позастравохідних), методів діагностики та сучасних підходів до лікування гастроезофагеальної рефлексної хвороби).Ключові слова: гастроезофагеальна рефелюксна хвороба, неінвазивна діагностика, фактори ризику, прогнозування перебігу.  СОВРЕМЕННЫЕ ВЗГЛЯДЫ НА ГЕРБ У ДЕТЕЙ: ПРОБЛЕМЫ И ПЕРСПЕКТИВЫСлободянюк А.Л.В последнее время больше внимания уделяется заболеванием верхних отделов пищеварительного тракта у детей, в том числе и ГЭРБ, как причине, которая приводит к нарушению качества жизни уже у детей школьного возраста, а в дальнейшем и у людей молодого возраста. Ученые пришли к консенсусу, что все обследования, которые используются в педиатрической практике должны быть максимально доступными, простыми и неинвазивными, насколько это позволяет состояние ребенка. Остается открытым вопрос о целесообразности проведения ФЭГДС всем пациентам с жалобами на изжогу и другими симптомами ГЭРБ, вопросы применения УЗИ пищевода у детей в качестве дополнительного метода обследования, использование опросников в педиатрической практике, формирование алгоритмов прогнозирования течения заболевания и определения профилактических мероприятий индивидуально для каждого пациента.Итак, целью этой работы было выполнить обзор современной литературы по проблемным вопросам клинических проявлений, факторов риска, диагностики, прогнозирования течения гастроэзофагеальной рефлексной болезни у детей разного возраста (по вопросам основных этиологических и патогенетических факторов, клинических проявлений (пищеводных и внепищеводных), методов диагностики и современных подходов к лечению гастроэзофагеальной рефлексной болезни).Ключевые слова: гастроэзофагеальная рефелюксная болезнь, неинвазивная диагностика, факторы риска, прогнозирование течения.


TRAUMA ◽  
2021 ◽  
Vol 22 (3) ◽  
pp. 12-19
Author(s):  
A.N. Kosiakov ◽  
A.Ye. Loskutov ◽  
K.A. Hrebennikov ◽  
A.V. Miloserdov ◽  
Ye.M. Fedin ◽  
...  

Background. Additive technologies are increasingly making their way from university laboratories and high-tech industries into routine clinical practice and even into our everyday lives. Any enthusiast, having a PC and a 3D printer at his or her disposal, can create any physical object — from children’s toys to works of art. The presence on the market of a wide range of software pro-ducts, equipment, and consumables along with the data from mo-dern diagnostic methods, a high level of training and cooperation between doctors and engineers provide practical medicine with unprecedented opportunities. We are finally able to fully customize our treatment and diagnostic procedures: to perform precise preoperative planning; to draw up a detailed plan of the operation; to rehearse the intervention on full-scale anatomical prototypes using a standard tool; to conduct the surgery as quickly and atraumatically as possible; to minimize risks; to ensure the optimal functional result and to manufacture and install customized implants in the most difficult cases. The purpose was to draw the attention of our distinguished colleagues to the aspects of application of additive technologies in modern orthopaedic practice, to introduce them into the history and current state of medical prototyping, as well as to share technological nuances with them. Materials and methods. While writing this article, we incorporated the data of recent publications in specialized domestic and foreign periodicals, several monographs, materials from thematic conferences, the results of informal conversations with colleagues in the operating rooms, at the computer and production site, as well as our own experience (over 200 cases of prototyping). Conclusions. The availability of equipment, software, and consumables allows for the introduction of additive technology into the everyday practice of nearly every modern orthopaedic and trauma clinic.


2019 ◽  
Vol 23 (3) ◽  
pp. 283-289
Author(s):  
Y. A. Revzoeva ◽  
E. Y. Shakurova

The article defines the significance and relevance of the problem of endometriosis during pregnancy. 10% of women in the reproductive period have different localization of endometriosis. 25% of pregnancies with endometriosis are complicated by preterm labor. The article presents a clinical case of intra-abdominal bleeding in a 28-year-old pregnant woman with retrocervical endometriosis at gestation age of 32 weeks and 6 days. The article covers the results of examination and special diagnostic procedures of intra-abdominal bleeding in pregnant women with retrocervical endometriosis. The main diagnostic methods were the study of past medical history, ultrasound examination, and laboratory tests. Due to their infrequency during pregnancy internal bleedings present difficulties in their diagnosis. Ultrasound reliably revealed a large amount of fluid in the abdominal cavity and small pelvis and excluded the presence of intrauterine bleeding. Clinical and laboratory tests indicated the severity of the patient's condition. Symptoms of moderate fetal distress were also identified. Therefore, a decision was made about an emergency delivery by the cesarean section followed by an abdominal revision. During the cesarean section, 500 ml of blood in the form of dark blood clots was found in the abdominal cavity. The condition of the premature newborn was in conformity with his gestational age. The source of bleeding were the of endometriosis on the back wall of the uterus. These focuses most likely caused hemoperitoneum. The revision of the abdominal cavity did not find any other foci of bleeding. The postoperative period was uneventful. The article provides general guidelines for the management of pregnant women with severe forms of endometriosis.


Sign in / Sign up

Export Citation Format

Share Document