THE GENUS ONOSMA L.: A COMPREHENSIVE REVIEW

Author(s):  
Aruna M. Rajapara ◽  
Mamta B. Shah

In medicinal plant field ethnopharmacological knowledge aggrandizes legibility for prioritizing species selection for future research opportunities. Many plant species representing the genus Onosma have been documented to be important in communities world-wide as evidenced by the numerous records on traditional medicinal and ethno-botanical information. Various species of the genus are used in the traditional medicinal systems in Europe and Asian countries especially in India, China, Turky and Pakistan. The literature on the species distribution and their characterization was compiled from different regional floras, regional revisions and databases. The information related to traditional uses, pharmacological activities and phytochemistry was systematically collected from the scientific databases including reference books, SciFinder, Scopus, PubMed and Google Scholar. Absence of comprehensive literature review on genus Onosma species led to design present study and dig the recorded documents to comparatively gauge magnitude of studies on each of the Onosma species through an exhaustive bibliographic evaluation of scientifically studied species of genus Onosma that are also taxonomically identified and are valued as traditional medicinal remedy for diseases in their countries of origin. The study hinted about lack of scientific literature on most of the species. A comprehensive bibliographic review on the geographical distribution, identification, traditional uses, phytochemistry, pharmacology and toxicology of the genus Onosma is attempted here to give insights into promising future drug discovery strategies. KEYWORDS: Onosma, Distribution, Traditional uses, Phyto-Pharmacology

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
A. K. M. Moyeenul Huq ◽  
Jamia Azdina Jamal ◽  
Johnson Stanslas

Persicaria hydropiper(L.) Delarbre, belonging to Polygonaceae family, is a common weed found in most of the temperate countries including Bangladesh, China, Malaysia, and Japan. The plant is also referred to as “marsh pepper” or “smart weed.” It appears to be a useful herb with evidence-based medicinal properties. The present work addresses the botanical description, traditional uses, phytochemistry, pharmacology, and toxicology ofP. hydropiper. All plant parts have been commonly used in the traditional systems of medicines. Flavonoids are the major group of phytochemical components followed by drimane-type sesquiterpenes and sesquiterpenoids, as well as phenylpropanoids. Different extracts and plant parts showed remarkable pharmacological activities including antioxidant, antibacterial, antifungal, antihelminth, antifeedant, cytotoxicity, anti-inflammatory, antinociceptive, oestrogenicity, antifertility, antiadipogenicity, and neuroprotection. Mutagenicity and acute and subchronic toxicities of the plant were also reported.P. hydropiperhas tremendous medicinal properties that could further be investigated for the development of evidence-based herbal products.


2021 ◽  
Vol 11 (6) ◽  
pp. 13829-13849

Grapes (Vitis vinifera L.) are commonly known grape species that belong to the Vitis genus in the Vitaceae family and come from western Asia and southern Europe. This review consists of traditional uses, phytochemical compounds, nutritional constituents, pharmacological activities, genotoxicological studies, and toxicity studies of V. vinifera. The data were obtained from scientific databases and search engines such as PubMed, Elsevier, Springer, Frontiers, Google Scholar, Scopus, Science Direct, and MDPI. In some countries, grapes used for traditional uses, such as drug therapy for blood-forming, anemia, allergies, wound care, colds and flu, carminative, bronchitis, diarrhea, and anti-phlegm. The main phytochemical compounds in V. vinifera are phenolic compounds, aromatic acids, flavonoids, proanthocyanidins, and stilbenoids. Nutritional constituents can be found in grapevines, i.e., proteins, lipids, carbohydrates, minerals, and vitamins. Parts of the grapevines had a wide variety of biological activities, i.e., antioxidant, antiviral, antiplatelet, antifungal, anticataract, antiobesity, anticholinergic, anti-sunburn, anti-inflammatory, and wound-healing activities. The phytochemical compounds content in each part of the grapevines were different. Each pharmacological activity depends on the grapevine's phytochemical compounds, components used, and extraction type. However, more studies are needed regarding the genotoxicity and toxicity of V. vinifera.


2021 ◽  
Vol 89 (4) ◽  
pp. 50
Author(s):  
Christina Barda ◽  
Maria-Eleni Grafakou ◽  
Ekaterina-Michaela Tomou ◽  
Helen Skaltsa

Knowledge within the field of phytochemistry research has accelerated at a tremendous speed. The excess of literature reports featuring plants of high ethnopharmacological importance, in combination with our interest in the Asteraceae family and traditional medicine, led us to acknowledge the value of the Achillea L. genus. In a broad context, the various Achillea species are used around the globe for the prevention and treatment of different diseases, including gastrointestinal problems, haemorrhages, pneumonia, rheumatic pains, diuresis, inflammation, infections, and wounds, as well as menstrual and gynaecologic abnormalities. The present review aims to provide and summarize the recent literature (2011–2021) on the phytochemistry of the Achillea genus. In parallel, this study attempts to bridge the reports on the traditional uses with modern pharmacological data. Research articles that focused on secondary metabolites, traditional uses and pharmacological activities were collected from various scientific databases such as Pubmed, ScienceDirect, Reaxys and Google Scholar. This study revealed the presence of 141 phytochemicals, while 24 traditionally used Achillea spp. were discussed in comparison to current data with an experimental basis.


Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4294 ◽  
Author(s):  
Jianmei Zhang ◽  
Stephanie Triseptya Hunto ◽  
Yoonyong Yang ◽  
Jongsung Lee ◽  
Jae Youl Cho

Tabebuia impetiginosa, a plant native to the Amazon rainforest and other parts of Latin America, is traditionally used for treating fever, malaria, bacterial and fungal infections, and skin diseases. Additionally, several categories of phytochemicals and extracts isolated from T. impetiginosa have been studied via various models and displayed pharmacological activities. This review aims to uncover and summarize the research concerning T. impetiginosa, particularly its traditional uses, phytochemistry, and immunopharmacological activity, as well as to provide guidance for future research. A comprehensive search of the published literature was conducted to locate original publications pertaining to T. impetiginosa up to June 2020. The main inquiry used the following keywords in various combinations in titles and abstracts: T. impetiginosa, Taheebo, traditional uses, phytochemistry, immunopharmacological, anti-inflammatory activity. Immunopharmacological activity described in this paper includes its anti-inflammatory, anti-allergic, anti-autoimmune, and anti-cancer properties. Particularly, T. impetiginosa has a strong effect on anti-inflammatory activity. This paper also describes the target pathway underlying how T. impetiginosa inhibits the inflammatory response. The need for further investigation to identify other pharmacological activities as well as the exact target proteins of T. impetiginosa was also highlighted. T. impetiginosa may provide a new strategy for prevention and treatment of many immunological disorders that foster extensive research to identify potential anti-inflammatory and immunomodulatory compounds and fractions as well as to explore the underlying mechanisms of this herb. Further scientific evidence is required for clinical trials on its immunopharmacological effects and safety.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
S. Prabhu ◽  
S. Vijayakumar ◽  
Raju Ramasubbu ◽  
P. K. Praseetha ◽  
K. Karthikeyan ◽  
...  

Abstract Background Bauhinia racemosa is not familiarly known in Asian countries due to its limited existence and lack of medicinal information. It is commonly used as a medicine, ornamental plant, fence plant, and fodder for livestock since ancient times. It is also used as a landfill tree to avoid soil erosion of the forest. Main body In South India, people cultivate this plant in their premises in order to protect themselves from the effects of thunder. In this review, the various research prospects of this plant have been analyzed and are summarized. The aim of this review is to provide the traditional uses, phytochemicals and pharmacological activities of B. racemosa, and to highlight the current pharmacological developments of this medicinal plant. Conclusions The B. racemosa has immense therapeutic potential for treating diseases with both traditional and pharmacological applications. But many traditional uses of B. racemosa have not been validated by current investigations in the aspects of pharmaceutical. Until now, research on phyto-constituents from B. racemosa has not been done in an extensive way. Hence, the identified phytochemicals of B. racemosa should also be subjected to pharmacological studies to illuminate the biological mechanisms of these unreported secondary metabolites for the prevention of diseases or microbial infections and other health disorders of human and animal races.


2016 ◽  
Vol 44 (02) ◽  
pp. 197-226 ◽  
Author(s):  
Le-Le Zhang ◽  
Ke Tian ◽  
Zheng-Hai Tang ◽  
Xiao-Jia Chen ◽  
Zhao-Xiang Bian ◽  
...  

Carthamus tinctorius L. is a multifunctional cash crop. Its flowers and seeds are extensively used in traditional herbal medicine in China, Korea, Japan, and other Asian countries, for treating various ailments such as gynecological, cardiovascular, and cerebrovascular diseases as well as blood stasis and osteoporosis. More than 100 compounds have been isolated and identified from C. tinctorius. Flavonoids and alkaloids, especially the quinochalcone c-glycoside hydroxysafflor yellow A, N-(p-Coumaroyl)serotonin, and N-feruloylserotonin, are responsible for most of the pharmacological activities of C. tinctorius. In this paper, comprehensive and up-to-date information on the phytochemistry and pharmacology of C. tinctorius is presented. This information will be helpful for further explorations of the therapeutic potential of C. tinctorius and may provide future research opportunities.


Author(s):  
Manish Kapoor ◽  
Gurdeep Kaur ◽  
Navneet Kaur ◽  
Chanchal Sharma ◽  
Kajal Batra ◽  
...  

The genus Hibiscus belongs to the mallow family, Malvaceae comprising of about 275 species growing in tropical and sub tropical areas. The various species of genus Hibiscus have been used as traditional medicine all over the world. There are numerous reports of their traditional medicinal uses in various countries like India, Nigeria, China, and Srilanka etc. to cure various ailments such as hypertension, cardiac diseases, stomach-ache, urine problems, skin diseases and many more. Based on the historical knowledge, various pharmacological and phytochemical studies on some species of the genus Hibiscus have been done. Nevertheless, there are no up-to-date articles published which can provide an overview of pharmacological effects of the genus Hibiscus. Therefore, the main objective of the review article is to provide a systematic comprehensive summary of traditional uses, phytochemistry and pharmacology of the genus Hibiscus and to build up a correlation between its traditional ethano-botanical uses and pharmacological activities so as to find some advanced research opportunities in this field. The given information on the ethano-botanical uses, phytoconstituents and various medicinal properties of the genus Hibiscus was gathered from the online scientific databases through search in Google, Google Scholar, Science Direct, NCBI, Pubmed, Springer Link, Research Gate by using some keywords as. Besides these websites other published literature and unpublished Ph.D. thesis and M.Sc. dissertation were also consulted. Previously conducted research revealed that the genus contains good amount of phytoconstituents such as antioxidants, phytosterols, saponins, lignin, essential oils, glycosides, and anthocyanins etc. Presence of these bioactive compounds in the crude extracts of the plants make it suitable for various medicinal properties like anti inflammatory, anti-diabetic, anti-obesity, anti-proliferative, anti-ulcer, hypersensitive, hypolipidemic, hepatoprotective, nephroprotective and many more. Additionally, this review article showed that mainly two species of the genus i.e. H. rosa-sinensis and H. sabdariffa have been explored for their pharmacological activities. There are few reports on some other species like H. tiliaceous, H. microanthus, H. asper, H. acetosella. This review highlights the medicinal potential of the plant Hibiscus due to its unique blend of phytochemicals. These phytoconstituents can be further assessed and subjected to clinical trials for their proper validations. Although large amount of the data regarding pharmacological effects has already been added to the existing reservoir but still potential of certain species like H. radiatus, H. hirtus, H. moschetous, H. trionum and many more is not yet unveiled and can be considered as future prospects that need to be worked out.  Graphical Abstract: 


2020 ◽  
Vol 11 (3) ◽  
pp. 10664-10678

The Pyrostegia genus of the Bignoniaceae family. This genus is consists of four species and indigenous to South America. The plants of this genus are being applied in traditional uses in Brazil. This review of the scientific work about Pyrostegia genus was highlighting and updating their traditional uses, phytochemical compounds, pharmacological activities, genotoxicity tests, and toxicity studies. The information was systematical with the scientific literature database, including Elsevier, Google Scholar, PubMed, Science Direct, and Scopus, and Springer. The literature survey showed various traditional uses of Pyrostegia genus, such as drugs to therapy diarrhea, coughing, vitiligo, jaundice, and respiratory system-related diseases, i.e., colds, coughs, and bronchitis. Phytochemical compounds from the Pyrostegia genus have shown the presence of flavonoids, phenolic compounds, phenylpropanoids, phenylethanoid glycosides, triterpenes, and sterols. The extract of Pyrostegia genus has a variety of pharmacology actions, i.e., antioxidant, antimicrobial, antifungal, anti-inflammatory, wound healing activities, antinociceptive, analgesic, vasorelaxant activities, antitumor, cytotoxic, hepatoprotective, antitussive, anthelmintic, hyperpigmented, treatment of sickness behavior, estrogenic, antihypertensive, and immunomodulatory. Pyrostegia genus is considerably used in traditional medicines and has various pharmacological activities. However, most species of Pyrostegia genus must be further researched concerning its chemical constituents and pharmacological activities.


2014 ◽  
Vol 42 (03) ◽  
pp. 523-542 ◽  
Author(s):  
Ming-Qiu Shan ◽  
Jing Shang ◽  
An-Wei Ding

Platycladus orientalis leaves (Cebaiye) have been used for thousands of years as traditional Chinese medicine (TCM). According to the theory of TCM, they are categorized as a blood-cooling and hematostatic herb. In clinical practice, they were usually prescribed with heat-clearing herbs to reinforce the efficacy of hemostasis. The review provides the up-to-date information from 1980 to present that is available on the botany, processing research, phytochemistry, pharmacology and toxicology of the leaves. The information is collected from scientific journals, books, theses and reports via library and electronic search (Google Scholar, Pubmed and CNKI). Through literature reports, we can find that the leaves show a wide spectrum of pharmacological activities, such as anti-inflammatory, antioxidant, antimicrobial, disinsection, anticancer, diuretic, hair growth-promoting, neuroprotective and antifibrotic activities. Diterpene and flavonoids would be active constituents in P. orientalis leaves. Many studies have provided evidence for various traditional uses. However, there is a great need for additional studies to elucidate the mechanism of blood-cooling and hematostatic activity of the leaves. Therefore, the present review on the botany, traditional uses, phytochemistry and toxicity has provided preliminary information for further studies of this herb.


Author(s):  
Tahmida Shamsuddin ◽  
Muhammad Shaiful Alam ◽  
Md. Junaid ◽  
Rasheda Akter ◽  
S. M. Zahid Hosen ◽  
...  

Background:: Adhatoda vasica (Nees.) of family Acanthaceae has been used in the Southeast tropical zone as it is efficacious against headache, colds, cough, whooping cough, fever, asthma, dyspnea, phthisis, jaundice, chronic bronchitis and diarrhea and exhibits commendable pharmacological activities. Objective: The aim of the review is to provide a systematic overview of pharmacological activities with toxicity and clinical assessment, phytochemistry of A. vasica along with its characterization, geographical observation, phenology, traditional uses as well as an organized representation of the findings. Method: The overall information of A. vasica were collected from various resources including books, review papers, research papers and reports which were obtained by an online search of worldwide-accepted scientific databases. ChemDraw software was used to draw the compounds’s structure. Results: Phytochemical review on A. vasica has led to the collection of 233 compounds of different types such as alkaloids, flavonoids, essential oils, terpenoids, fatty acids, phenols etc. It is a promising source of phytopharmaceutical potential agent that exhibits diverse pharmacological activities including antibacterial, antifungal, hepatoprotective, anti-ulcer, abortifacient, antiviral, anti-inflammatory, thrombolytic, hypoglycemic, anti-tubercular, antioxidant and antitussive activities. Conclusions: The sufficient number of studies on ethno-pharmacology, traditional uses and pharmacological activities of A. vasica are conducted. Furthermore, it is necessary to study the activity of chemical constituents for new drug design and discovery from natural products.


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