scholarly journals Phytochemistry and Evidence-Based Traditional Uses of the Genus Achillea L.: An Update (2011–2021)

2021 ◽  
Vol 89 (4) ◽  
pp. 50
Author(s):  
Christina Barda ◽  
Maria-Eleni Grafakou ◽  
Ekaterina-Michaela Tomou ◽  
Helen Skaltsa
Keyword(s):  
Recent Literature ◽  
Current Data ◽  
Research Articles ◽  
Evidence Based ◽  
Pharmacological Activities ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Gastrointestinal Problems ◽  
Pharmacological Data ◽  
Asteraceae Family

Knowledge within the field of phytochemistry research has accelerated at a tremendous speed. The excess of literature reports featuring plants of high ethnopharmacological importance, in combination with our interest in the Asteraceae family and traditional medicine, led us to acknowledge the value of the Achillea L. genus. In a broad context, the various Achillea species are used around the globe for the prevention and treatment of different diseases, including gastrointestinal problems, haemorrhages, pneumonia, rheumatic pains, diuresis, inflammation, infections, and wounds, as well as menstrual and gynaecologic abnormalities. The present review aims to provide and summarize the recent literature (2011–2021) on the phytochemistry of the Achillea genus. In parallel, this study attempts to bridge the reports on the traditional uses with modern pharmacological data. Research articles that focused on secondary metabolites, traditional uses and pharmacological activities were collected from various scientific databases such as Pubmed, ScienceDirect, Reaxys and Google Scholar. This study revealed the presence of 141 phytochemicals, while 24 traditionally used Achillea spp. were discussed in comparison to current data with an experimental basis.

scholarly journals Ethnobotanical, Phytochemical, Pharmacological, and Toxicological Aspects ofPersicaria hydropiper(L.) Delarbre

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
A. K. M. Moyeenul Huq ◽  
Jamia Azdina Jamal ◽  
Johnson Stanslas
Keyword(s):  
Major Group ◽  
Evidence Based ◽  
Pharmacological Activities ◽  
Herbal Products ◽  
Plant Parts ◽  
Traditional Uses ◽  
Botanical Description ◽  
Medicinal Properties ◽  
Pharmacology And Toxicology ◽  
Phytochemical Components

Persicaria hydropiper(L.) Delarbre, belonging to Polygonaceae family, is a common weed found in most of the temperate countries including Bangladesh, China, Malaysia, and Japan. The plant is also referred to as “marsh pepper” or “smart weed.” It appears to be a useful herb with evidence-based medicinal properties. The present work addresses the botanical description, traditional uses, phytochemistry, pharmacology, and toxicology ofP. hydropiper. All plant parts have been commonly used in the traditional systems of medicines. Flavonoids are the major group of phytochemical components followed by drimane-type sesquiterpenes and sesquiterpenoids, as well as phenylpropanoids. Different extracts and plant parts showed remarkable pharmacological activities including antioxidant, antibacterial, antifungal, antihelminth, antifeedant, cytotoxicity, anti-inflammatory, antinociceptive, oestrogenicity, antifertility, antiadipogenicity, and neuroprotection. Mutagenicity and acute and subchronic toxicities of the plant were also reported.P. hydropiperhas tremendous medicinal properties that could further be investigated for the development of evidence-based herbal products.

scholarly journals Phytochemical Compounds and Pharmacological Activities of Vitis vinifera L.: An Updated Review

2021 ◽  
Vol 11 (6) ◽  
pp. 13829-13849
Keyword(s):  
Vitis Vinifera ◽  
Wound Care ◽  
Biological Activities ◽  
Vitis Vinifera L ◽  
Pharmacological Activities ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Western Asia ◽  
Phytochemical Compounds ◽  
Nutritional Constituents

Grapes (Vitis vinifera L.) are commonly known grape species that belong to the Vitis genus in the Vitaceae family and come from western Asia and southern Europe. This review consists of traditional uses, phytochemical compounds, nutritional constituents, pharmacological activities, genotoxicological studies, and toxicity studies of V. vinifera. The data were obtained from scientific databases and search engines such as PubMed, Elsevier, Springer, Frontiers, Google Scholar, Scopus, Science Direct, and MDPI. In some countries, grapes used for traditional uses, such as drug therapy for blood-forming, anemia, allergies, wound care, colds and flu, carminative, bronchitis, diarrhea, and anti-phlegm. The main phytochemical compounds in V. vinifera are phenolic compounds, aromatic acids, flavonoids, proanthocyanidins, and stilbenoids. Nutritional constituents can be found in grapevines, i.e., proteins, lipids, carbohydrates, minerals, and vitamins. Parts of the grapevines had a wide variety of biological activities, i.e., antioxidant, antiviral, antiplatelet, antifungal, anticataract, antiobesity, anticholinergic, anti-sunburn, anti-inflammatory, and wound-healing activities. The phytochemical compounds content in each part of the grapevines were different. Each pharmacological activity depends on the grapevine's phytochemical compounds, components used, and extraction type. However, more studies are needed regarding the genotoxicity and toxicity of V. vinifera.

scholarly journals Phytochemistry, Traditional Uses and Pharmacological Properties of the Genus Opopanax W. D. J. Koch: A Mini-Review

2020 ◽  
Vol 26 (2) ◽  
pp. 99-106
Author(s):  
Alev Önder ◽  
Lutfun Nahar ◽  
Sushmita Nath ◽  
Satyajit D. Sarker
Keyword(s):  
Traditional Medicine ◽  
Mediterranean Region ◽  
Antimicrobial Activities ◽  
Evidence Based ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Phytochemical Profile ◽  
The Mediterranean ◽  
Antioxidant And Antimicrobial Activities

The genus Opopanax W.D.J. Koch is a member of the Apiaceae family, distributed throughout the Mediterranean region and comprises only three recognized and well-defined species, O. chironium (L.) W.D.J. Koch, O. hispidus (Friv.) Griseb. and O. persicus Boiss. The species of this genus with yellow flowers are well-known in traditional medicine and consumed as food. This review critically appraises published literature on the phytochemistry, traditional usages, and pharmacological activities of the genus Opopanax. In addition, it provides evidence to suggest that the plants from this genus have potential phytotherapeutic applications. Previous phytochemical and bioactivity studies revealed that the genus Opopanax predominantly produces coumarins, diterpenes, phenolics, and phthalides, and possesses various biological and pharmacological properties, including anticancer, antioxidant and antimicrobial activities. The phytochemical profile and pharmacological activities of the genus Opopanax could be useful for further study and might find additional medicinal applications in evidence-based phytotherapy

THE GENUS ONOSMA L.: A COMPREHENSIVE REVIEW

2021 ◽  
pp. 219-227
Author(s):  
Aruna M. Rajapara ◽  
Mamta B. Shah
Keyword(s):  
Scientific Literature ◽  
Species Selection ◽  
Future Research ◽  
Asian Countries ◽  
Pharmacological Activities ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Future Drug ◽  
Pharmacology And Toxicology ◽  
Selection For

In medicinal plant field ethnopharmacological knowledge aggrandizes legibility for prioritizing species selection for future research opportunities. Many plant species representing the genus Onosma have been documented to be important in communities world-wide as evidenced by the numerous records on traditional medicinal and ethno-botanical information. Various species of the genus are used in the traditional medicinal systems in Europe and Asian countries especially in India, China, Turky and Pakistan. The literature on the species distribution and their characterization was compiled from different regional floras, regional revisions and databases. The information related to traditional uses, pharmacological activities and phytochemistry was systematically collected from the scientific databases including reference books, SciFinder, Scopus, PubMed and Google Scholar. Absence of comprehensive literature review on genus Onosma species led to design present study and dig the recorded documents to comparatively gauge magnitude of studies on each of the Onosma species through an exhaustive bibliographic evaluation of scientifically studied species of genus Onosma that are also taxonomically identified and are valued as traditional medicinal remedy for diseases in their countries of origin. The study hinted about lack of scientific literature on most of the species. A comprehensive bibliographic review on the geographical distribution, identification, traditional uses, phytochemistry, pharmacology and toxicology of the genus Onosma is attempted here to give insights into promising future drug discovery strategies. KEYWORDS: Onosma, Distribution, Traditional uses, Phyto-Pharmacology

scholarly journals The Traditional Uses, Phytochemistry and Pharmacology of Genus Hibiscus: A Review

2021 ◽  
pp. 1-37
Author(s):  
Manish Kapoor ◽  
Gurdeep Kaur ◽  
Navneet Kaur ◽  
Chanchal Sharma ◽  
Kajal Batra ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Review Article ◽  
Pharmacological Effects ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Tropical Areas ◽  
Medicinal Properties ◽  
Phytochemical Studies

The genus Hibiscus belongs to the mallow family, Malvaceae comprising of about 275 species growing in tropical and sub tropical areas. The various species of genus Hibiscus have been used as traditional medicine all over the world. There are numerous reports of their traditional medicinal uses in various countries like India, Nigeria, China, and Srilanka etc. to cure various ailments such as hypertension, cardiac diseases, stomach-ache, urine problems, skin diseases and many more. Based on the historical knowledge, various pharmacological and phytochemical studies on some species of the genus Hibiscus have been done. Nevertheless, there are no up-to-date articles published which can provide an overview of pharmacological effects of the genus Hibiscus. Therefore, the main objective of the review article is to provide a systematic comprehensive summary of traditional uses, phytochemistry and pharmacology of the genus Hibiscus and to build up a correlation between its traditional ethano-botanical uses and pharmacological activities so as to find some advanced research opportunities in this field. The given information on the ethano-botanical uses, phytoconstituents and various medicinal properties of the genus Hibiscus was gathered from the online scientific databases through search in Google, Google Scholar, Science Direct, NCBI, Pubmed, Springer Link, Research Gate by using some keywords as. Besides these websites other published literature and unpublished Ph.D. thesis and M.Sc. dissertation were also consulted. Previously conducted research revealed that the genus contains good amount of phytoconstituents such as antioxidants, phytosterols, saponins, lignin, essential oils, glycosides, and anthocyanins etc. Presence of these bioactive compounds in the crude extracts of the plants make it suitable for various medicinal properties like anti inflammatory, anti-diabetic, anti-obesity, anti-proliferative, anti-ulcer, hypersensitive, hypolipidemic, hepatoprotective, nephroprotective and many more. Additionally, this review article showed that mainly two species of the genus i.e. H. rosa-sinensis and H. sabdariffa have been explored for their pharmacological activities. There are few reports on some other species like H. tiliaceous, H. microanthus, H. asper, H. acetosella. This review highlights the medicinal potential of the plant Hibiscus due to its unique blend of phytochemicals. These phytoconstituents can be further assessed and subjected to clinical trials for their proper validations. Although large amount of the data regarding pharmacological effects has already been added to the existing reservoir but still potential of certain species like H. radiatus, H. hirtus, H. moschetous, H. trionum and many more is not yet unveiled and can be considered as future prospects that need to be worked out.  Graphical Abstract: 

Adhatoda vasica (Nees.): A review on its botany, traditional uses, phytochemistry, pharmacological activities and toxicity

2021 ◽  
Vol 21 ◽  
Author(s):  
Tahmida Shamsuddin ◽  
Muhammad Shaiful Alam ◽  
Md. Junaid ◽  
Rasheda Akter ◽  
S. M. Zahid Hosen ◽  
...  
Keyword(s):  
Whooping Cough ◽  
Chemical Constituents ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Tropical Zone ◽  
Adhatoda Vasica ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Different Types ◽  
Promising Source

Background:: Adhatoda vasica (Nees.) of family Acanthaceae has been used in the Southeast tropical zone as it is efficacious against headache, colds, cough, whooping cough, fever, asthma, dyspnea, phthisis, jaundice, chronic bronchitis and diarrhea and exhibits commendable pharmacological activities. Objective: The aim of the review is to provide a systematic overview of pharmacological activities with toxicity and clinical assessment, phytochemistry of A. vasica along with its characterization, geographical observation, phenology, traditional uses as well as an organized representation of the findings. Method: The overall information of A. vasica were collected from various resources including books, review papers, research papers and reports which were obtained by an online search of worldwide-accepted scientific databases. ChemDraw software was used to draw the compounds’s structure. Results: Phytochemical review on A. vasica has led to the collection of 233 compounds of different types such as alkaloids, flavonoids, essential oils, terpenoids, fatty acids, phenols etc. It is a promising source of phytopharmaceutical potential agent that exhibits diverse pharmacological activities including antibacterial, antifungal, hepatoprotective, anti-ulcer, abortifacient, antiviral, anti-inflammatory, thrombolytic, hypoglycemic, anti-tubercular, antioxidant and antitussive activities. Conclusions: The sufficient number of studies on ethno-pharmacology, traditional uses and pharmacological activities of A. vasica are conducted. Furthermore, it is necessary to study the activity of chemical constituents for new drug design and discovery from natural products.

Phytochemistry and Pharmacology of the genus Zanthoxylum (Rutaceae): A review

2019 ◽  
Vol 09 ◽  
Author(s):  
Japheth O. Ombito
Keyword(s):  
Secondary Metabolites ◽  
Global Biodiversity Information Facility ◽  
Pharmacological Activities ◽  
Scientific Databases ◽  
Plant Parts ◽  
Pharmacological Studies ◽  
Pharmacological Data ◽  
Warm Temperate ◽  
Biodiversity Information ◽  
Science Information

Background: The approximately 250 accepted species of the genus Zanthoxylum (Rutaceae) are distributed in the warm temperate and subtropical regions of the world. Different plant parts of Zanthoxylum species have been used traditionally as medicines for various diseases affecting both human and animals. Based on the traditional knowledge, several phytochemical and pharmacological studies have been conducted. Objective: This review aims to offer an update describing the secondary metabolites isolated and described from the genus Zanthoxylum, covering literature published from January 2012 to mid-2019. Methods: The ethnobotanical, phytochemical and pharmacological data about Zanthoxylum species were searched and obtained from scientific databases such as Google Scholar, PubMed, SciFinder and Web of Science. Information about the accepted number of Zanthoxylum species was obtained from Global Biodiversity Information Facility. Results: The genus Zanthoxylum (Rutaceae) is a rich source of structurally diverse secondary metabolites with promising pharmacological activities. A total of 126 new secondary metabolites belonging to different classes of natural products, including alkaloids, amides, lignans and neolignans, coumarins, peptides, terpenoids and flavonoids reported from different Zanthoxylum species are described in the period covered by this rreview. It comprises data reported in more than 130 peer-reviewed articles and covers their source, isolation, structure elucidation and pharmacological activities (where available). Conclusion: A total of 126 new secondary metabolites isolated from the leaves, stems, stem barks, roots, root barks, fruits, and pericarps of Zanthoxylum species are reported. The findings show that plants of the genus Zanthoxylum show potential towards pharmacological activity, including anti-inflammatory, antimicrobial, cytotoxic, larvicidal, antioxidant, anticancer/antipoliferative, and antimycobacterial.

Nanoparticles Functionalized with Venom-Derived Peptides and Toxins for Pharmaceutical Applications

2020 ◽  
Vol 21 (2) ◽  
pp. 97-109 ◽  
Author(s):  
Ana P. dos Santos ◽  
Tamara G. de Araújo ◽  
Gandhi Rádis-Baptista
Keyword(s):  
Oral Absorption ◽  
Current Data ◽  
Pharmacological Activities ◽  
Venom Peptides ◽  
Essential Components ◽  
Wide Range ◽  
Different Types ◽  
Direct Use ◽  
Animal Venoms ◽  
Pharmaceutical Biotechnology

Venom-derived peptides display diverse biological and pharmacological activities, making them useful in drug discovery platforms and for a wide range of applications in medicine and pharmaceutical biotechnology. Due to their target specificities, venom peptides have the potential to be developed into biopharmaceuticals to treat various health conditions such as diabetes mellitus, hypertension, and chronic pain. Despite the high potential for drug development, several limitations preclude the direct use of peptides as therapeutics and hamper the process of converting venom peptides into pharmaceuticals. These limitations include, for instance, chemical instability, poor oral absorption, short halflife, and off-target cytotoxicity. One strategy to overcome these disadvantages relies on the formulation of bioactive peptides with nanocarriers. A range of biocompatible materials are now available that can serve as nanocarriers and can improve the bioavailability of therapeutic and venom-derived peptides for clinical and diagnostic application. Examples of isolated venom peptides and crude animal venoms that have been encapsulated and formulated with different types of nanomaterials with promising results are increasingly reported. Based on the current data, a wealth of information can be collected regarding the utilization of nanocarriers to encapsulate venom peptides and render them bioavailable for pharmaceutical use. Overall, nanomaterials arise as essential components in the preparation of biopharmaceuticals that are based on biological and pharmacological active venom-derived peptides.

Phytochemistry, Traditional Uses and Pharmacological properties of Enhydra fluctuans Lour: A Comprehensive Review.

2020 ◽  
Vol 21 ◽  
Author(s):  
Antica Barua ◽  
Muhammad Shaiful Alam ◽  
Md. Junaid ◽  
Yeasmin Akter ◽  
Syeda Samira Afrose ◽  
...  
Keyword(s):  
Sesquiterpene Lactone ◽  
Chemical Constituents ◽  
Phytochemical Analysis ◽  
Microbial Infection ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Cns Depressant ◽  
Isoflavone Glycoside ◽  
Online Library ◽  
Pharmacologically Active

Background: Enhydra fluctuans Lour, a tropical herb, commonly known as helencha or harkuch, belonging to family Asteraceae, and is an edible semi-aquatic herbaceous vegetable plant with serrate leaves, grows commonly in different parts of the world. Enhydra fluctuans possesses potential pharmacological role against inflammation, cancer, diarrhea, microbial infection, diabetes, and so on. Aim of the review: This review aims to provide the most current information on the botanical characterization, distribution, traditional uses, chemical constituents, as well as the pharmacological activities of Enhydra fluctuans Lour. Materials and methods: The recently updated information on Enhydra fluctuans was gathered from scientific journals, books, and worldwide accepted scientific databases via a library and electronic search (PubMed, Elsevier, Google Scholar, Springer, Scopus, Web of Science, Wiley online library. All of the full-text articles and abstracts related to Enhydra were screened. The most important and relevant articles were carefully chosen for study in this review. Results: Crude extracts and isolated compounds of Enhydra fluctuans Lour has been reported pharmacologically active against cytoprotective, analgesic and anti-inflammatory, antimicrobial, anticancer, anti-diarrhoeal, antihelmintic, CNS depressant, hepatoprotective, thrombolytic, antidiabetic, anti-oxidant, phagocytic and cytotoxic, and neuroprotective potential activities. Discussion: Phytochemical analysis from different studies has reported Germacranolide, Sesquiterpene lactone, Flavonoid, Essential oil, Steroid, Diterpenoid, Melampolide, Sesquiterpene lactone, Isoflavone glycoside as major compounds of Enhydra fluctuans Lour. Conclusions: However, more research is important to explore the mode of action of bioactive components of the plant and its therapeutic capabilities.

Phytochemical and Pharmacological Review on Two Herbs of Baijiangcao: Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

2020 ◽  
Vol 17 (5) ◽  
pp. 496-517
Author(s):  
Yangcheng Liu ◽  
Wei Liu ◽  
Jiaqi Wang ◽  
Yang Liu ◽  
Changlan Chen ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Volatile Components ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Scientific Databases ◽  
The Past ◽  
Current State ◽  
Patrinia Scabiosaefolia ◽  
Antiviral Activities

Patrinia scabiosaefolia Fisch. Trev. and Patrinia villosa (Thunb.) Juss, are two species of Patrinia recorded in the Chinese Pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In this review, data on chemical constituents and pharmacological profile of the two herbs are provided. This review discusses all the classes of the 223 compounds (phenylpropanoids, flavonoids, terpenes, saponins and volatile components, etc.) detected in the two herbs providing information on the current state of knowledge of the phytochemicals present in them. In the past three years, our research group has isolated and identified about more than 100 ingredients from the two herbs. Therefore, we published a systematic review of our research papers and studies on the two herbs were carried out using resources such as classic books about Chinese herbal medicine and scientific databases including Pubmed, Web of Science, SciFinder, CNKI. etc. The present review discusses the most thoroughly studied pharmacological activities (antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antitumor and antiviral activities) of the two herbs. This comprehensive review will be informative for scientists searching for new properties of these herbs and will be important and significant for the discovery of bioactive compounds from the two herbs and in complete utilization of Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss.

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