scholarly journals A Tribute to Experimental Physiology

2021 ◽  
pp. 21-35
Author(s):  
Elroy Patrick Weledji
Keyword(s):  
Human Physiology ◽  
Human Body ◽  
Human Subjects ◽  
Relevant Information ◽  
Modern Medicine ◽  
Adaptive Responses ◽  
Rational System ◽  
Clinical Investigations ◽  
Hospital Patients

Human physiology is the basis of any rational system of medicine. Experimental physiology gives insights into fundamental homeostatic and adaptive responses in health and further the knowledge of pathological mechanisms in diseases. Traditionally, a great deal of experimental physiology is done with mammalian and sub-mammalian vertebrates, frogs and toads but, increasing use is being made of experiments on human subjects, including the students themselves. The results of clinical investigations of hospital patients may also yield more detailed and relevant information than can be obtained from animal preparations. The interaction and collaboration between the scientist who aims to understand the functioning of the human body and the physician who aims to treat the malfunction is mandatory in modern medicine. This is corroborated by the fact that medicine is an art based on science. Keywords: Experimental Physiology; History; Tribute; Biography; Medicine

Opening up a New Field of Modern Medical Research 1

2020 ◽  
Author(s):  
Xiaoguang Li
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Human Body ◽  
Low Cost ◽  
Acupuncture Point ◽  
Modern Medicine ◽  
Body Structure ◽  
Special Effect ◽  
Special Knowledge ◽  
Opening Up

Modern medicine tells us that the human body is an organism composed of heart, lung, liver, kidney, spleen, stomach, brain, nerves, muscles, bones, blood vessels, blood and so on, while traditional Chinese medicine believes that besides these tissues and organs, the human body still has another part of the structure, traditional Chinese medicine calls them Jing Luo and Shu Xue. Jing Luo means the longitudinal line of the human body and the accompanying net, translated into English Meridians and Collaterals. Shu Xue means holes distributed on Jing Luo and outside Jing Luo, because stimulating Shu Xue's position by acupuncture, massage and other methods can cure diseases, so Shu Xue is translated into English acupuncture point, abbreviated as acupoint or point. Meridians and acupoints are the special knowledge of human body structure in traditional Chinese medicine. Traditional Chinese medicine not only draws the distribution map of the meridians and acupoints in the human body, but also has been using them to treat diseases for thousands of years. There are hundreds of these acupoints, stimulating each one by acupuncture, massage or other methods will have a special effect on the human body and can treat various diseases. But what effect does stimulating every acupoint have on the human body so that it can treat various diseases? The discussion of traditional Chinese medicine is vague and incomprehensible, and can not be proved by experiments. According to the author's research for more than 30 years, this paper makes a clear and accurate exposition of the effects on the human body and diseases that can be treated with acupoint massage. These statements can be proved by experiments, so they are believed to be reliable. It is hoped that meridians, acupoints and massage therapy can be incorporated into modern medicine and become a part of modern medicine after being proved by others through experiments. Massaging acupoints can not only treat many diseases that are difficult to be treated with drugs, but also have simple methods and low cost.

Tissue necrosis and passage of fluid due to cold stress from the thermally damaged human body peripherals: A mathematical model

2015 ◽  
Vol 04 (02) ◽  
pp. 1550012
Author(s):  
M. A. Khanday ◽  
Fida Hussain ◽  
Khalid Nazir
Keyword(s):  
Mathematical Model ◽  
Finite Element ◽  
Heat Equation ◽  
Cold Stress ◽  
Human Body ◽  
Human Subjects ◽  
Diffusion Equations ◽  
Tissue Necrosis ◽  
Cold Temperatures ◽  
Element Technique

The development of cold injury takes place in the human subjects by means of crystallization of tissues in the exposed regions at severe cold temperatures. The process together with the evaluation of the passage of fluid discharge from the necrotic regions with respect to various degrees of frostbites has been carried out by using variational finite element technique. The model is based on the Pennes' bio-heat equation and mass diffusion equations together with suitable initial and boundary conditions. The results are analyzed in relation with atmospheric temperatures and other parameters of the tissue medium.

Human Physiology: A Very Short Introduction

2021 ◽  
Author(s):  
Jamie A. Davies
Keyword(s):  
Human Physiology ◽  
Medical Research ◽  
Human Body ◽  
Ethical Issues ◽  
Physiological Mechanisms ◽  
Short Introduction ◽  
Process Information ◽  
Internal Parameters ◽  
The Creation

Human Physiology: A Very Short Introduction explores how the human body works, senses, reacts, and defends itself. Physiology is the science of life. It considers how human bodies are supplied with energy, how they maintain their internal parameters, the ways in which they gather and process information or take action, and the creation of new generations. This VSI examines the experiments undertaken to understand the interplay of the vast variety of physiological mechanisms and principles within us, and analyses the ethical issues involved. It also looks at how enhanced understandings of physiological knowledge can help inform medical research and care.

Gravidanotherapy

1934 ◽  
Vol 30 (11-12) ◽  
pp. 1078-1090
Author(s):  
M. E. Vinnikov
Keyword(s):  
Human Body ◽  
Experimental Verification ◽  
Well Being ◽  
Modern Medicine ◽  
The Other ◽  
New Method ◽  
Subjective Improvement ◽  
Clinical Observations ◽  
Other Hand ◽  
Methods Of Treatment

As any new method of treatment, gravidanotherapy is met with varying opinions. Some expect "miracles" from this method of treatment, believing that gravidanotherapy has found a new all-encompassing, excluding all other methods of treatment. On the other hand, there is an undeniable tendency to downplay or even completely deny the importance of gravidanotherapy. Finally, some authors consider gravidanotherapy as a method giving only subjective improvement of patients' well-being, the success of which is based on mass psychotherapy. Meanwhile, there is no doubt that gravidan, given its composition, should have a significant effect on the human body. It is only necessary that clinical observations and experimental verification give an unbiased assessment of the action of the drug and determine the place of gravidanotherapy in the arsenal of means of modern medicine.

Ultrasound Imaging Characterization of Soft Tissue Dynamics of the Seated Human Body

2020 ◽  
Vol 142 (6) ◽  
Author(s):  
Daisuke Yamada ◽  
Alperen Değirmenci ◽  
Robert D. Howe
Keyword(s):  
Ultrasound Imaging ◽  
Human Body ◽  
Human Subjects ◽  
Excitation Amplitude ◽  
Whole Body ◽  
Ultrasound Images ◽  
Body Dynamics ◽  
Excitation Pattern

Abstract To characterize the dynamics of internal soft organs and external anatomical structures, this paper presents a system that combines medical ultrasound imaging with an optical tracker and a vertical exciter that imparts whole-body vibrations on seated subjects. The spatial and temporal accuracy of the system was validated using a phantom with calibrated internal structures, resulting in 0.224 mm maximum root-mean-square (r.m.s.) position error and 13 ms maximum synchronization error between sensors. In addition to the dynamics of the head and sternum, stomach dynamics were characterized by extracting the centroid of the stomach from the ultrasound images. The system was used to characterize the subject-specific body dynamics as well as the intrasubject variabilities caused by excitation pattern (frequency up-sweep, down-sweep, and white noise, 1–10 Hz), excitation amplitude (1 and 2 m/s2 r.m.s.), seat compliance (rigid and soft), and stomach filling (empty and 500 mL water). Human subjects experiments (n = 3) yielded preliminary results for the frequency response of the head, sternum, and stomach. The method presented here provides the first detailed in vivo characterization of internal and external human body dynamics. Tissue dynamics characterized by the system can inform design of vehicle structures and adaptive control of seat and suspension systems, as well as validate finite element models for predicting passenger comfort in the early stages of vehicle design.

scholarly journals d-amino Acids in Health and Disease: A Focus on Cancer

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2205 ◽  
Author(s):  
Jacco J.A.J. Bastings ◽  
Hans M. van Eijk ◽  
Steven W. Olde Damink ◽  
Sander S. Rensen
Keyword(s):  
Amino Acids ◽  
Human Physiology ◽  
Amyotrophic Lateral Sclerosis ◽  
Human Body ◽  
Physiological Processes ◽  
Gut Barrier Function ◽  
Age Related ◽  
Health And Disease ◽  
Living Organisms ◽  
Lateral Sclerosis

d-amino acids, the enantiomeric counterparts of l-amino acids, were long considered to be non-functional or not even present in living organisms. Nowadays, d-amino acids are acknowledged to play important roles in numerous physiological processes in the human body. The most commonly studied link between d-amino acids and human physiology concerns the contribution of d-serine and d-aspartate to neurotransmission. These d-amino acids and several others have also been implicated in regulating innate immunity and gut barrier function. Importantly, the presence of certain d-amino acids in the human body has been linked to several diseases including schizophrenia, amyotrophic lateral sclerosis, and age-related disorders such as cataract and atherosclerosis. Furthermore, increasing evidence supports a role for d-amino acids in the development, pathophysiology, and treatment of cancer. In this review, we aim to provide an overview of the various sources of d-amino acids, their metabolism, as well as their contribution to physiological processes and diseases in man, with a focus on cancer.

scholarly journals Regulatory considerations for prospective patient care registries: lessons learned from the National Neurosurgery Quality and Outcomes Database

2013 ◽  
Vol 34 (1) ◽  
pp. E5 ◽  
Author(s):  
Anthony L. Asher ◽  
Matthew J. McGirt ◽  
Steven D. Glassman ◽  
Rachel Groman ◽  
Dan K. Resnick ◽  
...  
Keyword(s):  
Health Care ◽  
Clinical Data ◽  
Human Subjects ◽  
Modern Medicine ◽  
Lessons Learned ◽  
Quality Data ◽  
Clinical Registries ◽  
Restricted Environment ◽  
Current Resource ◽  
Prospective Longitudinal

Clinical registries have emerged in the current resource-restricted environment of modern medicine as useful and logical mechanisms for providing health care stakeholders with high-quality data related to the safety, effectiveness, and value of specific interventions. Temporal and qualitative requirements for data acquisition in the context of clinical registries have rapidly expanded as clinicians and other stakeholders increasingly recognize the central importance of this information to the intelligent transformation of health care processes. Despite the potential of more robust clinical data collection efforts to advance the science of care, certain aspects of these newer systems, particularly the prospective, longitudinal acquisition of clinical data and direct patient contact, represent areas of structural overlap between emerging quality improvement efforts and traditional models of human subjects research. This overlap has profound implications for the design and implementation of modern clinical registries. In this paper, the authors describe the evolution of clinical registries as important tools for advancing the science of practice, and review the existing federal regulations that apply to these systems.

Deafness

2020 ◽  
pp. 212-222
Author(s):  
Rebecca Sanchez
Keyword(s):  
Human Body ◽  
Human Subjects ◽  
Spring Water ◽  
Signed Languages ◽  
Signed Language

This chapter describes deaf experiences of reading, particularly those that occur in signed languages. It explores both visual and tactile methods of signed language reading and analyzes the ways these practices enable alternative theorizations of reading and its potentials as well as the reasons that referring to the processes of decoding signed language utterances as reading is appropriate. Specifically, it focuses on the implications of encountering the human body as text and the relationships between human subjects and language that become possible in such contexts through readings of several ASSL poems including Bernard Bragg’s “Flowers and Moonlight on Spring Water” and “The Pilot and the Eagle,” Ian Sanborn’s “Caterpillar,” and Ayisha Knight-Shaw’s “Until.”

Dynamic ease evaluation for 3D garment design

2018 ◽  
Vol 22 (2) ◽  
pp. 209-222
Author(s):  
Fangfang Zhang ◽  
Trevor John Little
Keyword(s):  
Human Body ◽  
Design Methodology ◽  
Human Subjects ◽  
Essential Element ◽  
The Body ◽  
Upper Arm ◽  
Core Element ◽  
Content Type ◽  
Comfort Evaluation ◽  
Garment Design

Purpose 3D garment design technology is developing rapidly thereby creating a need for different approaches to developing the patterns. The purpose of this paper is to evaluate the 3D dynamic ease distribution for a 3D garment design. Design/methodology/approach Standard garments were created from Size 2 to Size 14 for ten human subjects. Landmarks location on both human body and the standard garment under dynamic postures are recorded, and he fit and comfort evaluation of the standard garment were collected from the ten human subjects. Finally, these data were used to evaluate the 3D dynamic ease distribution for a 3D garment design. Findings 3D dynamic ease evaluation is challenging and the findings showed that the upper-arm design is a core element of the whole 3D garment design. The upper arm is not only a connecting part for both front and back pieces of the garment, but is also the main active part of the body, so it is the essential element to affect the comfort and fit of the garment under dynamic postures. Originality/value This research provides a novel 3D ease evaluation by analyzing the landmarks location of both human body and standard garment, and fit and comfort evaluation of the standard garment, which are all carried under dynamic postures.

scholarly journals Medical thermography: capabilities and perspectives

2018 ◽  
Vol 99 (2) ◽  
pp. 264-270 ◽  
Author(s):  
A M Morozov ◽  
E M Mokhov ◽  
V A Kadykov ◽  
A V Panova
Keyword(s):  
Human Body ◽  
Thermal Imaging ◽  
Diagnostic Method ◽  
High Efficiency ◽  
Clinical Medicine ◽  
Modern Medicine ◽  
Wide Range ◽  
History Of ◽  
Further Development ◽  
Physical Principles

Medical thermography is a modern diagnostic method that is currently gaining popularity due to high informative value and non-invasiveness. The aim of the study was to review the capabilities and prospects of medical thermography in modern medicine. The analysis of domestic and foreign literature on the application of medical thermography methods for the period of 2012-2017 was performed. The article presents the capabilities of imaging in various fields of medicine, evaluates the prospects of further development of the method, advances and disadvantages of thermography were identified. It also provides the review of the application of medical infrared thermography in clinical medicine. The experience of thermography application in various medical fields was investigated: angiology, otolaryngology, surgery, neurology, obstetrics and gyenecology, etc. Apart from medical aspects of this topic, the article discusses the history of medical thermography as well as provides the physical principles of this method. At present, thermal imaging can solve a wide range of problems: determining the presence of changes in the human body, and, as a result, the probability of pathology development, monitoring the effectiveness of treatment and rehabilitation. Every year more and more studies are carried out, confirming the high efficiency, reliability and safety of thermography, thermographic screenings are suggested, that can be assumed as prediction of future method's popularity.

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