Antipsychotics during Pregnancy: Pros and Cons
Background: As a general rule, medical professionals agree that it is best to avoid all drugs during pregnancy. Sometimes, however, drugs are essential to a woman’s health and well-being and to the safety of her fetus. Aim: The aim of this article is to review the pros and cons of pregnant women with schizophrenia remaining on antipsychotic medication. Method: The medical database, PubMed, was initially searched for literature in English of the last 5 years using the search terms: “pregnancy” and “antipsychotics”. Forty-four papers were selected. Results: There is no easy answer to the question of the wisdom of continuing antipsychotics during pregnancy. The reviewed literature suggests that the decision depends on the woman’s previous experience, the severity of her illness, her stage of pregnancy, and the specifics of the drug she is taking. Conclusion: As long as the woman is well-informed and competent to make decisions, she needs to carefully weigh benefits against risks to make the final determination. Whatever the decision, close clinical monitoring is warranted throughout pregnancy and the postpartum period. Keywords: Schizophrenia; Adverse Effects; Antipsychotic Discontinuation; Pregnancy