scholarly journals Awareness of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) use among population in Saudi Arabia

2019 ◽  
pp. 40-52
Author(s):  
Salwa Selim Abougalambou ◽  
Siham Abdullah Abdoun ◽  
Nora SayerAlharbi
Keyword(s):  
Saudi Arabia ◽  
Adverse Effects ◽  
Educational Status ◽  
Health Care Team ◽  
P Value ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Wide Range ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Background: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are one of the most frequently medicines used among the world. They are responsible for a wide range of adverse effects that are ranging from mild to life threatening in severe cases. The aimed of this study to ascertain user's knowledge about NSAIDs among population in Saudi Arabia Methodology: A cross-sectional study including 449 participants, who were users of NSAIDs in Saudi Arabia during October-December 2017. The data were collected using online questionnaire. The questionnaire contained basic socio-demographic information of participants and questions about the participant's knowledge of adverse effects, their types and NSAIDs uses. SPSS 23; including, frequency, description and chi square were used for analysis. Result: Majority, 80.6% of participants were female. Ibuprofen was the most common type of NSAIDs used by participants 61.9%. About 33% of participants were aware that these drugs can cause headache\dizziness and nausea\vomiting. However, 27.8% think that these drugs must be sold without a prescription. Additionally, the majority 87.5% feel that the use of NSAIDs is abused. There were a significant association between the availability of NSAIDs without a physician prescription with age, gender and employment status P-value (<0.05). While there was no significant association with educational status. Conclusion: the present study revealed a limited individual's knowledge about the NSAIDs adverse effects among Saudi Arabia. People need more educations or consultations with health care team specially the pharmacists. In a way to reduce their misuse or abuse or even unnecessarily prescribed. Keywords: NSAIDs; Saudi Arabia; Awareness; Knowledge; Saudi Arabia

scholarly journals Behavior of Medical Students toward Over-the-Counter Drugs in Comparison to Students from Other Faculties, Riyadh, Saudi Arabia

2021 ◽  
pp. 129-135
Author(s):  
Amar Fathi Mohamed Khalifa ◽  
Yasser Nabil AlKhudairy ◽  
Adel Ahmed Algahtani ◽  
Bandar Mohammed Abduljabbar ◽  
Fahad Majed Aldawsari ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Medical Students ◽  
Cross Sectional Study ◽  
P Value ◽  
Online Questionnaire ◽  
Self Medication ◽  
Cross Sectional ◽  
Over The Counter ◽  
Otc Drugs ◽  
Professional Guidance

Background: Over-the-counter-drugs (OTC) are drugs that can be obtained by patients without a prescription from a physician. In Saudi Arabia, it has been reported that more than half of university students practiced self-medication and used OTC drugs. Methods: An institutional-based cross-sectional study, among medical and non-medical students in Riyadh. The sample size was 421, by systemic random sampling. A pre-coded pre-tested online questionnaire was used. Data was analyzed using SPSS V 23. P-value ≤ 0.05 was considered significant. Results: There was no significant relationship between what the participants were majoring in and the usage of OTC drugs (p value= 0.373). Gender also had no relation with the use of OTC (p value= 0.168). Panadol appeared as the most commonly used OTC drug 62.9% for the relief of the most commonly mentioned factor which is headache 50.12%.  Conclusion: Medical education didn’t have much of an effect on the use of OTC drugs. Moreover, professional guidance or advice was not considered most of the time for taking OTC, but the majority of respondents portrayed good behavior towards usage of OTC.

Non-Steroidal Anti-Inflammatory Drugs: Usage and Co-prescription with Other Potentially Interacting Drugs in Elderly: a Cross-sectional Study

2019 ◽  
Author(s):  
Nuru Abdu ◽  
Samuel Teweldemedhin ◽  
Asmerom Mosazghi ◽  
Luwam Asfaha ◽  
Makda Teshale ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Drug Interactions ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Protective Agents ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Abstract Introduction: Globally, non-steroidal anti-inflammatory drugs (NSAIDs) usage in the elderly with chronic pain has been reported as frequent. Though it is fundamental in maintaining their quality of life, the risk of polypharmacy, drug interactions and adverse effects is of paramount importance as the elderly usually require multiple medications for their co-morbidities. If prescriptions are not appropriately monitored and managed, they are likely to expose patients to serious drug interactions and potentially fatal adverse effects. Thus, the objective of the study was to assess the appropriateness of NSAIDs use and incidence of NSAIDs related potential interactions in elderly. Methods: A descriptive cross-sectional study was conducted among elderly out-patients (aged 60 and above) who visited three hospitals in Asmara between August 22 and September 29, 2018. The sampling design was two-stage random sampling and data was collected using a questionnaire, exit interview and by abstracting information from patients’ clinical cards. Descriptive and analytical statistics including chi-square test and logistic regression were employed using SPSS. Results: A total of 285 elderly respondents were enrolled in the study with similar male to female ratio. One in four of all respondents were chronic NSAIDs users, of which 74.6% were not prescribed prophylactic gastro-protective agents (GPAs). About 20% of the elderly were involved in polypharmacy and nearly all of the encountered potential NSAIDs related interactions (n=322) with prescribed drugs were moderate. Diabetes and hypertension were significantly associated with chronic NSAIDs use (OR=3, 95% CI: 1.54, 5.84; OR=9.99, 95% CI: 4.46, 22.38) and incidence of drug interactions (OR=3.95, 95%CI: 1.92, 8.13; OR=3.12, 95%CI: 1.81, 5.33) while diabetes and cardiac problem were significantly associated with incidence of polypharmacy (OR=4.33, 95% CI: 2.36, 7.96; OR=3.56, 95% CI: 1.05, 12.11). Conclusion: Though the overall reflection of prescription pattern of NSAIDs during the study period was almost satisfactory, gastro-protective agents were poorly prescribed as a prophylaxis.

scholarly journals Knowledge, attitude and perception of Pakistanis towards COVID-19; a large cross-sectional survey

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zoya Fatima Rizwan Ladiwala ◽  
Rubaid Azhar Dhillon ◽  
Ibrahim Zahid ◽  
Omar Irfan ◽  
Muhammad Sharjeel Khan ◽  
...  
Keyword(s):  
Age Groups ◽  
Female Gender ◽  
Educational Status ◽  
Educational Interventions ◽  
Public Understanding ◽  
Cross Sectional Survey ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Adequate Knowledge ◽  
Wide Range

Abstract Background The Novel Coronavirus Disease (COVID-19) has created havoc globally as countries worldwide struggle to combat this pandemic. Since prevention and social isolation are known to be the only ways to prevent the spread of COVID-19, this has created challenges among the lower-middle income countries (LMIC) including Pakistan, as it battles between an under-resourced healthcare, an economic shutdown, and widespread myths and misconceptions. Therefore, a study was conducted to evaluate the knowledge, attitude and perceptions regarding COVID-19 as public understanding is vital to help facilitate the control of this outbreak. Methods A pre-validated online questionnaire was distributed among the general population of Pakistan from 1st to 12th June 2020. Descriptive statistics were analyzed using SPSS v25. Adequate knowledge was assigned as a score of > 4 (range: 0–8) and good perception as a score of > 3 (range: 0–5). Chi-square test was used to determine the significance of difference in knowledge and perception of COVID-19 with socio-demographic characteristics. Logistic regression analysis was run to identify factors associated with adequate knowledge and perception. P < 0.05 was considered as significant. Results A total of 1200 respondents participated in this study with a wide range of age groups and education. Majority of the respondents had adequate knowledge (93.3%) with a mean score of 6.59 ± 1.35, and good perception (85.6%) with a mean score of 4.29 ± 0.82. Significant differences in knowledge and perception were observed among genders, age groups, education and between students and employees in the healthcare and non-healthcare department. A multivariate analysis revealed a higher educational status and female gender to be significant predictors of adequate knowledge and perception. Conclusions Albeit the surge of COVID-19 cases in Pakistan, the participants demonstrated an overall adequate knowledge and good perception towards COVID-19. There is a need to follow the preventive protocols and dissemination of correct information through conducting educational interventions that target safe health practices and provide appropriate information on this infection.

scholarly journals AB0693 NON-STEROIDAL ANTI-INFLAMMATORY DRUGS DURING CORONAVIRUS 19 PANDEMIC: WHAT DO TUNISIAN RHEUMATOLOGISTS THINK?

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1379.3-1380
Author(s):  
H. Ferjani ◽  
H. Boussaa ◽  
K. Maatallah ◽  
H. Khalfalli ◽  
D. Kaffel ◽  
...  
Keyword(s):  
Infectious Complications ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Pain Medications ◽  
Data Collection And Analysis ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
The Impact ◽  
Similar Risk ◽  
Standardize Treatment

Background:Concerns over the safety of non-steroidal anti-inflammatory drugs (NSAIDs) use during severe acute respiratory syndrome associated with coronavirus 19 disease (covid-19) have raised. NSAIDs are one of the most commonly prescribed and used pain medications for acute and chronic rheumatic diseases such as spondyloarthritis (SpA) and osteoarthritis.Objectives:This study aimed to assess the impact of covid-19 pandemic on NSAIDs prescription.Methods:A cross-sectional web survey was disseminated to all Tunisian rheumatologists through a mailing system and social media. The French version was accessible on Google form. It included close-ended questions about the prescription of NSAIDs during covid-19 pandemic. Participation was anonymous. Data collection and analysis was performed between January the first and January 30, 2021.Results:Among one hundred and thirty Tunisian rheumatologists, thirty responded to the online questionnaire. Ninety percent of participants were women. The mean age of rheumatologists was 34 years [25-57]. The duration of practice was inferior to 5 years in 59.3%, between 5 and 10 years in 18.5%, and superior to 10 years in 22.2% of cases. Sixty-three percent of rheumatologists reported that their activity decreased during covid-19 pandemic. NSAIDs prescription was avoided as much as possible in 40.7% of cases.The participants indicated NSAIDs less frequently in 33.3% of cases, and as much as before the pandemic in one-quarter of cases.Rheumatologists believed that NSAIDs worsen the respiratory symptoms (67%), delay recovery (55%), and increase mortality (48%), hospitalization in intensive care (44%), and infectious complications (33%).The participants suggested that the most incriminated NSAIDs were: Ibuprofen (7.4%), indomethacin (7.4%), celecoxib (7.4%), and diclofenac (3.4%). The majority of rheumatologists (74%) believed that all NSAIDs had a similar risk.For patients with osteoarthritis, rheumatologists replaced NSAIDs with paracetamol and corticoids in 78% and 11% of cases, respectively. If mandatory, reducing NSAIDs doses or duration was an option in 22% and 74% of cases.For patients with SpA, half of rheumatologists did not change the treatment. However, the participants limited the use of NSAIDs or discontinued the treatment in patients with comorbidities. More than 60% of rheumatologists didn’t know the effect of NSAIDs in the post-covid-19 syndrome.Conclusion:Covid-19 pandemic has affected rheumatologists’ practice. Rheumatic disease management during this pandemic may be challenging. More evidence is mandatory to standardize treatment prescription, especially with NSAIDs.Disclosure of Interests:None declared

scholarly journals Community Perception and Acceptance of Patients with Prosthetic Devices after Disabilities in Riyadh, Saudi Arabia

2021 ◽  
Author(s):  
Mohammed Ibrahim Alhumaidan ◽  
Wazzan S. Al Juhani ◽  
Abdulmohsen A. Al Hussaini ◽  
Hussam S. Al Angari ◽  
Saad Z. Al Jabr ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Descriptive Analysis ◽  
Educational Status ◽  
P Value ◽  
Continuous Variables ◽  
Community Perception ◽  
Cross Sectional ◽  
Prosthetic Devices ◽  
The Mean ◽  
Acceptance Rates

Abstract BACKGROUND: It is well known that prostheses help people with special needs to adapt and have a better quality of life; however, the community’s perception and acceptance of patients with prosthetic devices due to their disabilities have not been fully assessed. The aim was to measure the community’s perception and acceptance of patients with prosthesis in Riyadh, Saudi Arabia. METHODS: A cross-sectional study was conducted from late 2019 using an online self-developed questionnaire, named the “Prosthesis Acceptance Assessment Test” (PAAT), which was developed in English for 20 items on a five-point Likert scale. The questionnaire was validated with a Cronbach’s score of 0.913 and a pilot was initially conducted on a sample (n=50). Thereafter, the questionnaire was distributed via social media for a wider reach within the community. The result of descriptive analysis was presented as a frequency with percentages. Categorical data were tested using chi-square or Fisher’s exact test. Continuous variables were tested for mean differences using students’ t-test and association using Pearson’s correlation. ANOVA was used to determine the difference in the mean scores of acceptance rates by educational status. A p-value less than 0.05 was considered significant. RESULTS: A total of 526 participants responded to the questionnaire, of which only 68 (12.9%) participants knew someone who had a prosthesis. The majority of participants were females (n= 292, 55.5%) and bachelor’s degree holders (n= 90, 26.1%). The acceptance rates were slightly higher in females (n= 78, 26.7%) than males (n= 58, 24.8%), with most participants (n= 390, 74.1%) not accepting of people with prosthesis. The mean scores of acceptance rates did not correlate with age (r2= 0.025, P= 0.565), and was not statistically significant when compared by gender (T= -1.688, P=0.092) and educational status (x2 = 0.105, P = 0.907). CONCLUSION: We found that most participants were not accepting of people with prosthesis. Reasons were not explored as there were no age, gender, or educational status differences that may have potentially explained the low rate of acceptance.

Heparin and proteoglycans as anti-inflammatory drugs

1996 ◽  
Vol 16 (01) ◽  
pp. 56-59
Author(s):  
D. J. Tyrrell ◽  
C. P. Page
Keyword(s):  
Inflammatory Diseases ◽  
Therapeutic Applications ◽  
Wide Range ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

SummaryEvidence continues to accumulate that the pleiotropic nature of heparin (beyond its anticoagulant potency) includes anti-inflammatory activities at a number of levels. It is clear that drugs exploiting these anti-inflammatory activities of heparin may offer exciting new therapeutic applications to the treatment of a wide range of inflammatory diseases.

scholarly journals COVID-19 Psychological Impact on Health Care Workers in Saudi Arabia

2021 ◽  
Vol 18 (11) ◽  
pp. 6076
Author(s):  
Hasan S. Alamri ◽  
Wesam F. Mousa ◽  
Abdullah Algarni ◽  
Shehata F. Megahid ◽  
Ali Al Bshabshe ◽  
...  
Keyword(s):  
Health Care ◽  
Saudi Arabia ◽  
Health Care Workers ◽  
Psychological Impact ◽  
Psychological Outcomes ◽  
Cross Sectional Survey ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Care Workers ◽  
The Impact

Objective: Little is known about the impact of Coronavirus (COVID-19) among the health care workers in Saudi Arabia. Therefore, the present study aimed to assess the psychological impact of COVID-19 among the health care workers. Methods: A cross-sectional survey was conducted from May till mid-July among 389 health care workers from government and private hospitals in Saudi Arabia. Data was collected using a pre-structured online questionnaire that measured adverse psychological outcomes, including the Patient Health Questionnaire-9 (PHQ-9) scale and the Generalized Anxiety Disorder 7-item (GAD-7) scale. The Pearson chi-square test was used to assess the distribution of depression and anxiety among health care workers. Results: A high level of anxiety was recorded among the health care workers, and 69.3% of health care workers below the age of 40 were found to have depression. There was a significant increase in depression among staff with chronic health problems (72.1% vs. 61.9%; p = 0.048). High anxiety levels were detected among young staff compared to others (68.7% vs. 43.8%; p = 0.001). Moreover, 82.1% of the female staff were anxious, as compared to 55.6% of the males (p = 0.001). Conclusions: We found increased prevalence of adverse psychological outcomes among the health care workers in Saudi Arabia during the outbreak of COVID-19. Therefore, there is a need for proper screening and development of corresponding preventive measures to decrease the adverse psychological outcomes.

scholarly journals Assessment of Saudi Parents’ Beliefs and Behaviors towards Management of Child Fever in Saudi Arabia—A Cross-Sectional Study

2021 ◽  
Vol 18 (10) ◽  
pp. 5217
Author(s):  
Mohamed N. Al Arifi ◽  
Abdulrahman Alwhaibi
Keyword(s):  
Saudi Arabia ◽  
Side Effects ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Electronic Thermometer ◽  
And Behavior

Objective: Fever alone can lead to rare serious complications in children, such as febrile seizures. The aim of this study is to assess the knowledge, beliefs, and behavior of parents toward fever and its management. Methods: A cross-sectional study using an online questionnaire was applied over a period of 3 months, from January to March 2018, to parents who were living in Saudi Arabia. The inclusion criteria were a parent who is a resident of Saudi Arabia, with at least one child aged 6 years or less, while incomplete questionnaires, having a child aged more than 6 years, or parents who were not living in Saudi Arabia were excluded. Results: A total of 656 parents completed the questionnaire. More than two-thirds of the subjects were female, the majority of whom were aged between 25–33 years old. The best-reported place to measure the temperature of children was the armpit (46%), followed by the ear (28%) and the mouth (10.7%). More than half of the parents considered their children feverish at a temperature of 38 °C. The majority of parents (79.7%) reported that the most serious side effects of fever were seizure, brain damage (39.3%), coma (29.9%), dehydration (29.7%), and death (25%). The most common method used to measure a child’s temperature was an electronic thermometer (62.3%). The most common antipyretic was paracetamol (84.5%). Conclusions: Our study demonstrates the good knowledge of parents in identifying a feverish temperature using the recommended route and tools for measuring body temperature.

scholarly journals The Level of Lymphedema Awareness among Women with Breast Cancer in the Kingdom of Saudi Arabia

2021 ◽  
Vol 18 (2) ◽  
pp. 627
Author(s):  
Fatmah Alsharif ◽  
Wedad Almutairi ◽  
Faygah Shibily ◽  
Fatmah Alhothari ◽  
Fidaa Batwa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Saudi Arabia ◽  
Soft Tissues ◽  
Demographic Data ◽  
Medical Team ◽  
Online Questionnaire ◽  
Kingdom Of Saudi Arabia ◽  
Cross Sectional ◽  
Convenience Sample ◽  
The Status

Background: Lymphedema is a condition in which excessive fluid accumulates in soft tissues. It is a common complication of breast cancer treatments. It can lead to serious consequences and interfere with the activity of daily living. This study aimed to determine the level of awareness of breast-cancer-related lymphedema (BCRL) among women with breast cancer in the Kingdom of Saudi Arabia. This was a descriptive quantitative cross-sectional design that included a convenience sample of women diagnosed with breast cancer in the Kingdom of Saudi Arabia. Data were collected by distributing a self-administrated online questionnaire consisting of four parts, including demographic data (five items), the status of education about BCRL (three items), basic medical history of breast cancer (six items), and BCRL level of awareness of risk factors and management (nine items). Results: In total, 95 out of 135 of participants did not know about lymphedema, 119 of the participants (88.1%) did not receive any explanation about the possibility of lymphedema from their medical team before surgery, and 121 of them (89.6%) did not receive it after surgery. The most significant factor affecting participants’ level of awareness regarding BCRL was the lack of information about the possibility of BCRL occurrence, which was not provided to them by the medical team. Recommendation: Early and continuous education for future management is essential to prevent problems related to BCRL and improve quality of life.

scholarly journals Perioperative nutrition care and dietetic practices in the scope of bariatric surgery in Saudi Arabia using adapted protocols for evaluation

2021 ◽  
Vol 9 ◽  
pp. 205031212110361
Author(s):  
Elham Abbas Aljaaly
Keyword(s):  
Bariatric Surgery ◽  
Saudi Arabia ◽  
Care Process ◽  
Cross Sectional Survey ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Nutrition Risk ◽  
Nutrition Care ◽  
Management Protocol ◽  
Perioperative Nutrition

Objectives: This study evaluates the availability of perioperative nutritional care protocols and the practices of bariatric registered dietitians in Saudi Arabia. The primary outcomes of the study were conducted using an adapted American survey “with permission.” Methods: A cross-sectional survey of a selected 32 dietitians providing bariatric services completed a self-administered online questionnaire from 12 hospitals in Jeddah, Saudi Arabia. Results: All surveyed dietitians were females, mainly Saudi nationals (93.9%, n = 30), and accredited by the Saudi Commission for Health Specialties (93.8%, n = 30). Only 37.5% (n = 6) of the dietitians were specialized in bariatric surgery. Perioperative common practices of dietitians included a conduct of screening for nutrition risk before (44%, n = 14) and after surgery (62.5%, n = 20) and applied a nutrition management protocol that is mainly based on the application of nutrition care process (62.5%, n = 20). Dietitians (81%, n = 26) reported the importance of having standardized protocols for nutritional management of patients undoing bariatric surgery, where 69% (n = 22) confirmed the availability of pre-operative written protocols in hospitals and 75% (n = 24) confirmed the existence of post-operative protocols. Pre-operative practices included using approaches for weight loss before surgery, for example, very low and low-calorie diet. Dietitians (25%, n = 8) see two to ten patients per month. The sleeve gastrectomy procedure is the most often performed surgery. Conclusion: This is the first study to evaluate the perioperative nutrition care protocols and practices related to bariatric surgery in Saudi Arabia. Perioperative bariatric protocols are available, but some dietitians are not aware of their availability and contents. Researchers emphasize the importance of creating national protocols by the Saudi Credentials Body to standardize practices within the field.

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