scholarly journals Familial traits of attached and unattached earlobe in human population of different age groups- A case study of district Nawabshah, Pakistan

2021 ◽  
Vol 3 (4) ◽  
pp. 112-115
Author(s):  
Sharmeen Najeeb Ashraf ◽  
Nehal Najeeb Ashraf ◽  
Haiqa Sami ◽  
Bisma Aslam ◽  
Sabin Muhammad Israr ◽  
...  
Keyword(s):  
Molecular Biology ◽  
Old Age ◽  
Human Population ◽  
Age Groups ◽  
Age Group ◽  
Dominant Feature

This study aimed to evaluate frequency of attached earlobes (dominant) and unattached earlobes (recessive) traits in humans of different age groups. This study was conducted in the Department of Molecular Biology and Genetics of Shaheed Benazir Bhutto University, Shaheed Benazir Abad from September to October 2020. A total of 200 families with attached and unattached earlobes were included by using non-probability convenient sampling. Data was collected regarding attached and unattached earlobes of different people. The data was collected and analysed by using SPSS version 21.0. Results of the study suggested that unattached earlobes were dominant feature, and the attached earlobe feature appears to be recessive among all 200 families. We observed that the dominant feature of the unattached earlobe was more common in the 1 to 20 years’ age group, while the recessive feature of the attached earlobe was common in 31 to 45 years old age group. The study concluded that unattached earlobes can be observed in people of every age group and associated with family traits.

scholarly journals Clinical and radiological imaging as prognostic predictors in COVID-19 patients

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Maha Ibrahim Metwally ◽  
Mohammad Abd Alkhalik Basha ◽  
Mohamed M. A. Zaitoun ◽  
Housseini Mohamed Abdalla ◽  
Hanaa Abu Elazayem Nofal ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Old Age ◽  
Fatal Outcome ◽  
Age Groups ◽  
Lower Lobe ◽  
Chest Ct ◽  
Imaging Features ◽  
Age Group ◽  
Significant Relation ◽  
Ct Features

Abstract Background Since the announcement of COVID-19 as a pandemic infection, several studies have been performed to discuss the clinical picture, laboratory finding, and imaging features of this disease. The aim of this study is to demarcate the imaging features of novel coronavirus infected pneumonia (NCIP) in different age groups and outline the relation between radiological aspect, including CT severity, and clinical aspect, including age, oxygen saturation, and fatal outcome. We implemented a prospective observational study enrolled 299 laboratory-confirmed COVID-19 patients (169 males and 130 females; age range = 2–91 years; mean age = 38.4 ± 17.2). All patients were submitted to chest CT with multi-planar reconstruction. The imaging features of NCIP in different age groups were described. The relations between CT severity and age, oxygen saturation, and fatal outcome were evaluated. Results The most predominant CT features were bilateral (75.4%), posterior (66.3%), pleural-based (93.5%), lower lobe involvement (89.8%), and ground-glass opacity (94.7%). ROC curve analysis revealed that the optimal cutoff age that was highly exposed to moderate and severe stages of NCIP was 38 years old (AUC = 0.77, p < 0.001). NCIP was noted in 42.6% below 40-year-old age group compared to 84% above 40-year-old age group. The CT severity was significantly related to age and fatal outcome (p < 0.001). Anterior, centrilobular, hilar, apical, and middle lobe involvements had a significant relation to below 90% oxygen saturation. A significant negative correlation was found between CT severity and oxygen saturation (r = − 0.49, p < 0.001). Crazy-paving pattern, anterior aspect, hilar, centrilobular involvement, and moderate and severe stages had a statistically significant relation to higher mortality. Conclusion The current study confirmed the value of CT as a prognostic predictor in NCIP through demonstration of the strong relation between CT severity and age, oxygen saturation, and the fatal outcome. In the era of COVID-19 pandemic, this study is considered to be an extension to other studies discussing chest CT features of COVID-19 in different age groups with demarcation of the relation of chest CT severity to different pattern and distribution of NCIP, age, oxygen saturation, and mortality rate.

scholarly journals Neuropsychological Differences Related to Age in Dementia with Lewy Bodies

2017 ◽  
Vol 7 (2) ◽  
pp. 188-194 ◽  
Author(s):  
Yasuhiro Nagahama ◽  
Tomoko Okina ◽  
Norio Suzuki
Keyword(s):  
Old Age ◽  
Memory Impairment ◽  
Dementia With Lewy Bodies ◽  
Memory Performance ◽  
Oldest Old ◽  
Age Groups ◽  
Lewy Bodies ◽  
Age Group ◽  
Recent Memory ◽  
Better Than

Background/Aims: To examine the influence of age on neuropsychological performances in dementia with Lewy bodies (DLB) and Alzheimer disease (AD) patients. Methods: We examined memory, executive, and visuo-constructional performances in 202 DLB patients and 236 AD patients. We divided the subjects into three age groups (65–74, 75–84, and 85–95 years old), and evaluated the differences in neuropsychological performances. Results: Recent memory in the DLB group was significantly better than that in the age-matched AD group when comparing the age groups 65–74 years and 75–84 years; however, memory impairment in the DLB patients in the age group 85–95 years was comparable with that in the age-matched AD patients. In contrast to recent memory, the other assessed neuropsychological performances, such as visuospatial and executive functions, showed no significant change in differences between the DLB and AD groups with advancing age. Conclusion: Our study revealed that the nature of memory impairment in DLB patients changes according to age. DLB patients in the young-old and old-old age groups showed significantly better memory performance than the age-matched AD patients, whereas memory performance of the DLB patients in the oldest-old age group was similar to that of the age-matched AD patients. This may be associated with the increased rate of coexisting AD pathology in DLB patients with older age.

Prevalence of non-pathogenic types of gastrointestinal protozoa in population in Slovakia and their potential importance in the aspect of public health

2018 ◽  
Vol 63 (4) ◽  
pp. 819-825 ◽  
Author(s):  
Adriána Dudlová ◽  
Pavol Jarčuška ◽  
Silvia Jurišová ◽  
Zuzana Vasilková ◽  
Vladimír Krčméry ◽  
...  
Keyword(s):  
Human Population ◽  
Statistical Significance ◽  
Age Groups ◽  
Gastrointestinal Symptoms ◽  
Developed Countries ◽  
Age Group ◽  
Potential Importance ◽  
Blastocystis Hominis ◽  
Factors Affecting ◽  
Total Prevalence

Abstract The aim of the research was to determine the prevalence of non-pathogenic protozoa circulating in the human population of Slovakia. We particularly focused on the socially deprived areas with poor sanitation conditions, as they are one of the factors affecting the transmission of these infections. Within this study, 2760 people were coprologically screened for the presence of protozoan cysts. The analyzed group comprised 1173 men and 1587 women from different regions of Slovakia. The total prevalence (2.03%) of non-pathogenic protozoa species was determined. The prevalence of Entamoeba coli was 0.80%, the prevalence of Endolimax nana 0.58%, and the prevalence of Blastocystis hominis was 0.65%. The presence of non-pathogenic protozoa was more frequent in women than that in men, in all age groups. The highest incidence of Entamoeba coli was found in children aged one month – seven years (0.79%), the lowest in the age group of 19–88 years (0.66%). Endolimax nana was most frequent in 8–18 year-olds (0.95%), where the statistical significance was found (p<0.05). The prevalence of Blastocystis hominis by the age group ranged from 0.39 to 0.95%. We did not find any statistical significance (p>0.05) for Entamoeba coli, and similarly for Blastocystis hominis associated with the sex and age. Although the circulation of non-pathogenic protozoa in the human population is far from being limited to the developing countries, their occurrence is also frequent in the population of developed countries. Despite their controversial pathogenicity, they should not be neglected, particularly in the patients with gastrointestinal symptoms.

scholarly journals "It Is Not Good For Man To Be Alone" The Struggle against Loneliness in Old Age: Basic Assumptions for an Integrative Operational Concept –The Israeli Case

2017 ◽  
Vol 6 (1) ◽  
pp. 82
Author(s):  
Avi Bitzur ◽  
Eran Fisher
Keyword(s):  
Old Age ◽  
Local Level ◽  
Age Groups ◽  
The Elderly ◽  
Dominant Factor ◽  
Comprehensive Plan ◽  
Limited Scale ◽  
Operational Concept

The widespread expression saying that "loneliness is the No. 1 enemy of old age" has, in the 21st century, becomes obvious and banal now that suicide rates among the elderly in many countries and in Israel, the case study for this paper, is higher than among other age groups in those countries.Loneliness itself, its ramifications, consequences, and implications on the lives of the elderly have made it a dominant factor in terms of its potential damage.Old age and loneliness have been the subjects of many different definitions, studies and theories, but despite the quantity and quality of these attempts worldwide, and particularly in Israeli research, there is a conspicuous lack of any comprehensive plan that would address the implications and destructive effects of the loneliness experienced by the elderly. Many limited-scale programs exist on a local level, but they fail to address the clear need to eradicate menacing loneliness.The authors of this essay plan to outline basic principles for designing an operational concept for a national plan to combat the consequences and effects of depression among the elderly, using Israel as an example.This paper will begin with a review of the definitions and literature on the phenomenon of depression, and a review of the literature dealing with the unhealthy connection between old age and depression. We will then review various programs worldwide that deal with the phenomenon of loneliness and old age; continue to present data on the effects of loneliness on elderly Israelis; present various Israeli programs and projects that attempt to deal with this phenomenon; and conclude by detailing the proposed principles for a comprehensive operational approach that maps out this painful phenomenon in Israel and proposes a plan of action on how to best deal with it.

scholarly journals Trends in Poliovirus Seroprevalence in Kano State, Northern Nigeria

2018 ◽  
Vol 67 (suppl_1) ◽  
pp. S103-S109
Author(s):  
Harish Verma ◽  
Zubairu Iliyasu ◽  
Kehinde T Craig ◽  
Natalie A Molodecky ◽  
Utibeabasi Urua ◽  
...  
Keyword(s):  
Old Age ◽  
Age Groups ◽  
Significant Risk ◽  
Immunization Coverage ◽  
Neutralizing Antibody ◽  
Age Group ◽  
Parental Consent ◽  
Population Immunity ◽  
Antibody Titres ◽  
The Impact

Abstract Background Kano state has been a protracted reservoir of poliovirus in Nigeria. Immunity trends have been monitored through seroprevalence surveys since 2011. The survey in 2015 was, in addition, intended to assess the impact of use of inactivated poliovirus vaccine (IPV). Methods It was a health facility based seroprevalence survey. Eligible children aged 6-9, 12-15 and 19-22 months of age brought to the paediatrics outpatient department of Murtala Mohammad Specialist Hospital between 19 October and 6 November 2015, were screened for eligibility. Eligible children were enrolled after parental consent, history taken, physical examination conducted, and a blood sample collected to test for neutralizing antibody titres against the three poliovirus serotypes. Results Overall, 365 results were available in the three age groups. In the 6-9-month-old age group, the seroprevalence was 73% (95% confidence interval [CI] 64-80%), 83% (95% CI 75-88%), and 66% (95% CI 57-73%) for serotypes 1, 2, and 3, respectively. In the 12-15- and 19-22-month-old age groups, seroprevalence was higher but still remained <90% across serotypes. Seroprevalence to serotypes 1 and 3 in 2015 was similar to 2014; however, for serotype 2 there was a significant improvement. IPV received in supplemental immunization activities was found to be a significant predictor of seropositivity among 6-9-month-old infants for serotypes 1 and 2. Conclusions Seroprevalence for serotypes 1 and 3 remains low (<80%) in 6-9-month-olds. This poses a significant risk for poliovirus spread if reintroduced into the population. Efforts to strengthen immunization coverage are imperative to secure and sustain high population immunity.

scholarly journals Association of HMGA2 Gene Variation with Height in Specific Pediatric Age Categories

2008 ◽  
Vol 1 ◽  
pp. GEI.S944 ◽  
Author(s):  
Struan F.A. Grant ◽  
Mingyao Li ◽  
Jonathan P. Bradfield ◽  
Cecilia E. Kim ◽  
Kiran Annaiah ◽  
...  
Keyword(s):  
Old Age ◽  
Strong Association ◽  
Age Groups ◽  
Age Group ◽  
Pediatric Age ◽  
Single Nucleotide ◽  
Gene Variation ◽  
Genome Wide ◽  
A Genome ◽  
Minor Alleles

Background Recently an association was demonstrated between the single nucleotide polymorphism (SNP), rs1042725, within the HMGA2 locus and height as a consequence of a genome wide association (GWA) study of this trait in adults; this observation was also reported in children aged 7–11 years old. Objective We examined in our Caucasian childhood cohort the effects of two strong surrogates for this SNP at this locus with height, rs8756 and rs7968902, with respect to the same pediatric age category but also in children grouped separately as younger and older. Methods Utilizing data from an ongoing GWA study in our cohort of 2,619 Caucasian children with measurements for height, we investigated the association of the previously reported variation at the HMGA2 locus with this height treated as a quantitative trait (age and sex corrected) in childhood in the 2–6 (n = 706), 7–11 (n = 617) and 12–18 (n = 1293) years old categories. Results The minor alleles of rs8756 and rs7968902 respectively (strong surrogates for rs1042725 i.e. r 2 = 0.873 and 0.761 in the CEU HapMap respectively) were significantly associated with height in the 7–11 years old age group ( P = 3.53 × 10–3 and 2.82 × 10–4, respectively) However in the 2–6 and 12–18 years old age groups, no association was observed. Conclusions We observe a strong association with height in same age group of 7–11 years old as has been previously reported. However, in the under 7s and the over 11s, no such association was observed.

scholarly journals High Incidence of Severe Influenza among Individuals over 50 Years of Age

2011 ◽  
Vol 18 (11) ◽  
pp. 1918-1924 ◽  
Author(s):  
Anna J. X. Zhang ◽  
Kelvin K. W. To ◽  
Herman Tse ◽  
Kwok-Hung Chan ◽  
Kun-Yuan Guo ◽  
...  
Keyword(s):  
Influenza Vaccination ◽  
Incidence Rate ◽  
Old Age ◽  
H1n1 Virus ◽  
Severe Disease ◽  
Age Groups ◽  
Respiratory Viruses ◽  
World Health ◽  
Pandemic H1n1 ◽  
Age Group

ABSTRACTAge-specific epidemiological data on asymptomatic, symptomatic, and severe infections are essential for public health policies on combating influenza. In this study, we incorporated data on microbiologically confirmed infections and seroprevalence to comprehensively describe the epidemiology of pandemic H1N1 2009 influenza. Seroprevalence was determined from 1,795 random serum samples collected in our hospital in January 2007 (before the first wave of the pandemic) and March 2010 (after the second wave). Data on microbiologically confirmed infection and severe cases were obtained from the Centre for Health Protection in Hong Kong. Severe cases were most common in the 51- to 60-year-old age group. The microbiologically confirmed incidence rate was highest for children aged ≤10 years and dropped sharply for the adult population (ρ = −1.0;P< 0.01), but the incidence rate for severe disease was highest for the 51- to 60-year-old age group. For the 51- to 60-year-old age group, the seroprevalence was similar to that for the younger age groups, but the proportion of severe cases relative to seroprevalence was significantly higher than that for 11- to 50-year-old age groups. As judged from the percentage of specimens positive for other respiratory viruses compared with that for pandemic H1N1 virus, the impact of symptomatic disease due to pandemic H1N1 virus was higher than that for other respiratory viruses in people aged ≤50 years. In conclusion, the 51- to 60-year-old age group, which had the highest overall incidence and the highest rate of severe disease but is currently not considered by the World Health Organization to be an at-risk group, should be prioritized for influenza vaccination in areas where universal influenza vaccination is not practiced.

scholarly journals Prospective study of patients with membranous patch over the tonsil at GIMS, Kalaburagi

2020 ◽  
Vol 6 (12) ◽  
pp. 2194
Author(s):  
Renuka S. Melkundi ◽  
Siddaram Patil
Keyword(s):  
Age Groups ◽  
Immunization Coverage ◽  
Clinical Aspects ◽  
Age Group ◽  
Adult Age ◽  
Health Agencies ◽  
Infected Adult ◽  
Paediatric Age ◽  
The Government

<p><strong>Background:</strong> Current study was done to know various clinical aspects of membranous patch over the tonsil.</p><p><strong>Methods: </strong>Data for the study were collected from patients who presented with membranous patch over the tonsil in the department of ENT at GIMS, Kalaburagi from January 2019 to December 2019. This is a prospective case study. 225 patients were included in the study. Once patient was presented to us detailed history, examination and necessary investigations were done.</p><p><strong>Results:</strong> The present study included 225 patients out of which out of which females were 132 (59%) and males were 93 (41%). The predominant clinical features were sore throat (225 cases), fever (212 cases), dysphagia (90 cases) and bull neck (45 cases). The most common cause of membranous patch over tonsil was found to be diphtheria (68%) followed by streptococcal tonsillitis (30%) and others (2%). In our study microbiological investigations like Albert stain was positive in 153 cases and culture was positive in 140 cases.</p><p><strong>Conclusions: </strong>It was observed in our study that diphtheria constitutes the majority (68%) and the incidence of adult is almost on par with paediatric age group. Despite of UIP we have seen increased incidence in the adult age group. Hence it requires the health agencies and the Government to increase immunization coverage, as India has witnessed the highest number of cases in the world for the year 2015. As evident from the shift in age groups being infected, adult booster dose has to be introduced at 10 years interval.</p>

scholarly journals Association Between Social Support and Mental Health in Pre-Old and Old Age: Is It Different Depends on the Object? A Cross-Sectional Study

2020 ◽  
Author(s):  
Yaya Li ◽  
Mai Kabayama ◽  
Kei Kamide
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Old Age ◽  
Age Groups ◽  
Positive Association ◽  
Ordinary Least Squares ◽  
Age Group ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Emotional Social Support

Abstract Background The association of social support with mental health for the older adults has been well documented; however, object-specific support was rarely discussed. This study examined the relationships of multiple aspects of social support, especially focusing on objects of social support, across different aging stages. Methods We conducted a self-reported cross-sectional survey in Osaka, Japan in 2013. We analyzed 659 pre-old and 888 old age participants. SF-36v2 was used to measure mental health. Objects of social support was divided into 3 categories (kin, friends, community) with integrating sub-dimensions of social support such as instrumental / emotional social support (function) and provided / received social support (role). Ordinary least squares, controlled for covariates, was carried out to analyze the variation among three objects of social support on mental health in two age groups. Results The results showed a positive association within the pre-old age group but not within the old age group. For the pre-old age group, either emotional or instrumental social support either provided to or received from a community neighbor had a positive association, while emotional social support provided to kin or friends and instrumental support received from friends didn’t show any relation to mental health.Conclusions The relationship between social support and mental health varied by objects and age groups.

scholarly journals A Study on the Effects of Containment Policies and Vaccination on the Spread of SARS-CoV-2

2020 ◽  
Author(s):  
Vahid S. Bokharaie
Keyword(s):  
Age Structure ◽  
Compartmental Model ◽  
Herd Immunity ◽  
Age Groups ◽  
Age Group ◽  
Model Output ◽  
Monotone Systems ◽  
Different Populations ◽  
Different Levels

AbstractThis paper presents a method to predict the spread of the SARS-CoV-2 in a population with a known age-structure, and then, to quantify the effects of various containment policies, including those policies that affect each age-group differently. The model itself is a compartmental model in which each compartment is divided into a number of age-groups. The parameter of the model are estimated using an optimisation scheme and some known results from the theory of monotone systems such that the model output agrees with some collected data on the spread of SARS-CoV-2.To highlight the strengths of this framework, a few case studies are presented in which different populations are subjected to different containment strategies. They include cases in which the containment policies switch between scenarios with different levels of severity. Then a case study on herd immunity due to vaccination is presented. And then it is shown how we can use this framework to optimality distribute a limited number of vaccine units in a given population to maximise their impact and lower the total number of infectious individuals.MSC subclass92C60, 92C50

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