Prevalence of non-pathogenic types of gastrointestinal protozoa in population in Slovakia and their potential importance in the aspect of public health

Abstract The aim of the research was to determine the prevalence of non-pathogenic protozoa circulating in the human population of Slovakia. We particularly focused on the socially deprived areas with poor sanitation conditions, as they are one of the factors affecting the transmission of these infections. Within this study, 2760 people were coprologically screened for the presence of protozoan cysts. The analyzed group comprised 1173 men and 1587 women from different regions of Slovakia. The total prevalence (2.03%) of non-pathogenic protozoa species was determined. The prevalence of Entamoeba coli was 0.80%, the prevalence of Endolimax nana 0.58%, and the prevalence of Blastocystis hominis was 0.65%. The presence of non-pathogenic protozoa was more frequent in women than that in men, in all age groups. The highest incidence of Entamoeba coli was found in children aged one month – seven years (0.79%), the lowest in the age group of 19–88 years (0.66%). Endolimax nana was most frequent in 8–18 year-olds (0.95%), where the statistical significance was found (p<0.05). The prevalence of Blastocystis hominis by the age group ranged from 0.39 to 0.95%. We did not find any statistical significance (p>0.05) for Entamoeba coli, and similarly for Blastocystis hominis associated with the sex and age. Although the circulation of non-pathogenic protozoa in the human population is far from being limited to the developing countries, their occurrence is also frequent in the population of developed countries. Despite their controversial pathogenicity, they should not be neglected, particularly in the patients with gastrointestinal symptoms.

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Prevalence of type two diabetes mellitus in Jammu rural

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20180600 ◽

2018 ◽

Vol 6 (3) ◽

pp. 838

Author(s):

Sanjeev Kumar ◽

Ashima Badyal

Keyword(s):

Diabetes Mellitus ◽

Plasma Glucose ◽

Rural Areas ◽

Life Style ◽

Age Of Onset ◽

Age Groups ◽

Developed Countries ◽

Age Group ◽

Screening Programs ◽

Total Prevalence

Background: Diabetes Mellitus (DM) represents one of the biggest challenges in our century, affecting hundreds of millions people worldwide, both in developed countries and in developing ones, as well; the main cause being an unhealthy life style: unhealthy food, lack of physical exercise, which most of the times, lead to obesity.Methods: This study was conducted to estimate the prevalence of DM in various age groups and gender by analyzing the hospital record based data from August 2017- December 2017 at Sub-District Hospital, Hiranagar, Kathua, J and K. Fasting plasma glucose ≥ 126 mg% and random plasma glucose ≥ 200 mg% were taken as the diagnostic criteria for diagnosis of DM.Results: Out of the 3600 patients screened for DM, majority were in the age group of 41-50 (37.06 %). Net prevalence was found to be 4.7% (170) of the total. Prevalence among females and males was found to be 49.41% and 50.59% respectively. The trend showed prevalence of approximately 6% in the age group of 41-50 and 51-60, but >60 years showed comparatively less prevalence i.e. <5%.Conclusions: Various studies from time to time have also discussed the most disturbing trend being the shift in age of onset of diabetes to a younger age in the recent years, which could be attributed to changing life-style, even in the rural areas, with a high percentage not knowing that they were suffering from diabetes; therefore, active screening programs are recommended in order to diagnose this condition earlier.

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Family history of early onset acute lymphoblastic leukemia is suggesting genetic associations

Scientific Reports ◽

10.1038/s41598-021-90542-7 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Xinjun Li ◽

Kristina Sundquist ◽

Jan Sundquist ◽

Asta Försti ◽

Kari Hemminki

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Statistical Significance ◽

Age Groups ◽

Age Group ◽

Genetic Associations ◽

Sequencing Data ◽

Cancer Data ◽

Group 5 ◽

Prostate Cancers

AbstractChildhood acute lymphoblastic leukemia (ALL) has an origin in the fetal period which may distinguish it from ALL diagnosed later in life. We wanted to test whether familial risks differ in ALL diagnosed in the very early childhood from ALL diagnosed later. The Swedish nation-wide family-cancer data were used until year 2016 to calculate standardized incidence ratios (SIRs) for familial risks in ALL in three diagnostic age-groups: 0–4, 5–34 and 35 + years. Among 1335 ALL patients diagnosed before age 5, familial risks were increased for esophageal (4.78), breast (1.42), prostate (1.40) and connective tissue (2.97) cancers and leukemia (2.51, ALL 7.81). In age-group 5–34 years, rectal (1.73) and endometrial (2.40) cancer, myeloma (2.25) and leukemia (2.00, ALL 4.60) reached statistical significance. In the oldest age-group, the only association was with Hodgkin lymphoma (3.42). Diagnostic ages of family members of ALL patients were significantly lower compared to these cancers in the population for breast, prostate and rectal cancers. The patterns of increased familial cancers suggest that BRCA2 mutations could contribute to associations of ALL with breast and prostate cancers, and mismatch gene PMS2 mutations with rectal and endometrial cancers. Future DNA sequencing data will be a test for these familial predictions.

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The pediatric patient at a maxillofacial service: eye prosthesis

Brazilian Oral Research ◽

10.1590/s1806-83242006000300012 ◽

2006 ◽

Vol 20 (3) ◽

pp. 247-251 ◽

Cited By ~ 6

Author(s):

Beatriz Silva Câmara Mattos ◽

Maria Cecília Montagna ◽

Clemente da Silva Fernandes ◽

Antonio Carlos Lorenz Sabóia

Keyword(s):

Statistical Significance ◽

Age Groups ◽

Age Group ◽

Significance Level ◽

Gender And Age ◽

Child Patient ◽

Eye Prosthesis ◽

School Of Dentistry ◽

Prosthetic Eye ◽

Orbital Region

Congenital absence or loss of the ocular globe during childhood causes psycho-social and cosmetic disorders and compromise the normal development of the orbital region. The literature relating to congenital or acquired etiology, due to trauma or disease, demonstrates the necessity of prevention and early detection in order to minimize the sequelae and disturbances in orbital growth. Installation of an eye prosthesis is essential to the rehabilitation process, so as to produce satisfactory development of the region. In order to characterize a profile of the child patient with this condition, a survey was carried out at the Prosthetic Eye sector, Out-patient Clinic, Discipline of Maxillofacial Prosthodontics, School of Dentistry, University of São Paulo (FOUSP), during the period from 1988 to 2003. The 124 (14.02%) patients within the age group of 0-13 years registered for ocular prosthesis were divided into a first group of 64 patients (51.62%) with 0-7 years, and a second group of 60 patients (48.38%) with 8-13 years. Fifty nine were girls and 65 were boys. No statistical significance was observed regarding the distribution of genders in the two analyzed age groups (p = 0.069). However, there was statistical significance at the level of 0.01 in relation to etiology, with higher prevalence of congenital and pathological disturbances in the younger group and traumatic occurrences in the older group. The etiology also presented variation according to the gender, at the significance level of 0.05, where girls presented three times less trauma than boys in the older age group. The necessity of prosthetic ocular repair was evenly distributed along the childhood period and the eye losses that required prosthetic treatment equally affected both genders. However, the etiology of eye loss varied according to the considered gender and age bracket.

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Study on factors affecting fertility of Bangladeshi women

Z H Sikder Women’s Medical College Journal ◽

10.47648/zhswmcj.2020.v0102.02 ◽

2019 ◽

Vol 1 (Number 2) ◽

pp. 6-10

Author(s):

Monowar Ahmad Tarafdar ◽

Nadia Begum ◽

Shila Rani Das ◽

Sultana Begum ◽

Mehruba Afrin ◽

...

Keyword(s):

Middle Class ◽

Rural Area ◽

Age Groups ◽

Wealth Index ◽

Cross Sectional Study ◽

Reproductive Age ◽

Age Group ◽

Cross Sectional ◽

Lower Middle Class ◽

Factors Affecting

This is a cross sectional study conducted among Currently Married Women of Reproductive Age (CMWRA) with a sample size of 476 selected purposively using a semi-structured questionnaire in 2018 at Moulvibazar Sadar to explore the factors affecting fertility. The result shows that 55.26% respondents were within 35 years age whereas only 4.28% from age group 46-49 years age group, 33% of the respondents got married at <16 years of age and 18.70% were illiterate, 47.90% had primary education. It is evident that 76% of the respondents were from rural area; 88% were Muslims, 29.41% from lower middle class followed by upper middle class (25.42%) and poorest comprised only 7.56%. The result explored that 73.91% of the respondents were from age group 41-45 got married before 16 years of age followed by 36-40 years (68.24%), 46-49 years (66%), 20-25 and 26-30 years age groups 52.38% and 52.75% respectively; 73.33% of respondents from rural area got married at <16 years of age, 68.42% of the Muslim at <16 years. The study explored that 96.39% from poorer section and 83.33% from poorest section got married at <16 years of age. Current study revealed that 82.91% of the respondents having secondary education got married before 16 years of age followed by illiterate (82.02%). It is explored that the age at marriage is statistically associated with residence, education, wealth index and religion (p= 0.001, 0.03, 0.001, 0.001 respectively). We conclude that the sociodemographic condition contributes mostly to fertility differentials in Bangladesh.

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Factors Affecting The Survival Trend In Oesophageal Malignancy- A Hospital Based Study

TAJ Journal of Teachers Association ◽

10.3329/taj.v27i1.37613 ◽

2018 ◽

Vol 27 (1) ◽

pp. 38-43

Author(s):

MK Sarker ◽

MM Sarker ◽

MFK Bhuiyan ◽

MMR Khan ◽

ASMA Raihan

Keyword(s):

Cancer Patients ◽

Oesophageal Cancer ◽

Poor Prognosis ◽

Palliative Treatment ◽

Age Groups ◽

Curative Treatment ◽

Age Group ◽

Gastrointestinal Malignancy ◽

Factors Affecting ◽

Insidious Onset

Oesophageal cancer is a gastrointestinal malignancy with insidious onset and poor prognosis. The disease predominantly affects the older age groups with pick incidence between 60 to 70 years of age. The total number of oesophageal cancer patients available for the study within the stipulated time was 43. Among them 60.47% patients were male and 39.53% patients were female, 06.98% belonged to age group 31-40, 16.28% belonged to age group 41-50, 37.21% belonged to age group 51-60, 23.25% belonged to age group 61-70 and 16.28% patients were >70 years of age. Mean age was 59.95 years ± 12.63 SD. In our study, 33.3% survived ≤3 months, 09.1% 4–6 months, 15.2 % 7–9 months, 06.1% 10–12 months, 27.2% 13–24 months and 09.1% >24 months. Among the expired patients, 09.10% got curative treatment and rest of 90.90% got palliative treatment. Those who got curative treatment 66.7% survived 13–24 months and 33.3% > 24 months. Those who got palliative treatment 36.7% survived ≤3 months, 10.0% 4–6 months, 06.7% 10–12 months and 30.0% 13–24 months. Overall median survival was 08 months, for curative treatment 18 months and for palliative treatment 07 months.TAJ 2014; 27(1): 38-43

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Factors Affecting The Survival Trend In Carcinoma Stomach- A Hospital Based Study

TAJ Journal of Teachers Association ◽

10.3329/taj.v27i2.38989 ◽

2018 ◽

Vol 27 (2) ◽

pp. 44-49

Author(s):

MK Sarker ◽

MM Sarker ◽

NA Parveen ◽

PM Basak ◽

ASMA Raihan

Keyword(s):

Stomach Cancer ◽

Poor Prognosis ◽

Palliative Treatment ◽

Age Groups ◽

Curative Treatment ◽

Age Group ◽

Gastrointestinal Malignancy ◽

Factors Affecting ◽

Insidious Onset ◽

Carcinoma Stomach

Stomach cancer is a gastrointestinal malignancy with insidious onset and poor prognosis. The disease predominantly affects the older age groups with pick incidence between 60 to 70 years of age. The total number of stomach cancer patients available for the study within the stipulated time was 105. Among them 69.52% patients were male and 30.48% patients were female. 0.95% patient belonged to age group <20, 11.43% belonged to age group 21-30, 09.52% belonged to age group 31-40, 23.81% belonged to age group 41-50, 28.57% belonged to age group 51-60, 20.0% belonged to age group 61-70 and 05.72% patients were >70 years of age. Mean age was 54.91 years ± 13.42 SD. In our study, 45.6% survived <3 months, 15.8% 4–6 months, 07.0% 7–9 months, 14.0% 10–12 months, 10.6% 13–24 months and 07.0% >24 months. Among 57 expired patients, 14 got curative treatment and rest of 43 got palliative treatment. Those who got curative treatment, 36.4% survived 10–12 months, 45.5% 13–24 months and 18.1% > 24 months. Those who got palliative treatment 51.5% survived <3 months, 24.2% 4–6 months, 12.1% 7–9 months, 09.1% 10–12 months and 03.1% 13–24 months. Overall median survival was 06 months, for curative treatment 16 months and for palliative treatment 03 months.TAJ 2014; 27(2): 44-49

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TIME TRENDS OF HELICOBACTER PYLORI PREVALENCE IN ITAJAÍ - SC: A RETROSPECTIVE STUDY OF 25 YEARS BASED ON ENDOSCOPIC DATABASE

Arquivos de Gastroenterologia ◽

10.1590/s0004-2803.201900000-13 ◽

2019 ◽

Vol 56 (1) ◽

pp. 10-14 ◽

Cited By ~ 1

Author(s):

Fangio FERRARI ◽

Elisa Cantú Germano DUTRA ◽

Henrieli Correia ZANARDI ◽

Bruno Lorenzo SCOLARO ◽

Odemari Miranda FERRARI

Keyword(s):

Helicobacter Pylori ◽

Age Groups ◽

Developed Countries ◽

Helicobacter Pylori Infection ◽

Age Group ◽

Gradual Reduction ◽

Urease Test ◽

Significant Difference ◽

The Mean ◽

And Gender

ABSTRACT BACKGROUND: The bacterium Helicobacter pylori is strongly associated with the development of gastric adenocarcinoma. Currently, the prevalence in developed countries is 40%, but this value increases considerably in developing countries, which can reach rates bigger than 90%. OBJECTIVE: The objective of this study was to determine the mean and annual prevalence of Helicobacter pylori infection in patients from Itajaí during the period from July 1992 to April 2016, as well as the gender and age groups most affected. METHODS: After consent of the clinical director of the Gastroclinica Itajaí and confidentiality commitment about the research, the database of the Endoscopy Service of the clinic was evaluated. All the patients who underwent their first upper digestive endoscopy with urease test and/or histological analysis were included. The data were submitted to statistical analysis of prevalence by gender, age group and years of study, with subsequent correction through the confidence interval. RESULTS: The mean prevalence of Helicobacter pylori infection thru all years of study was 50.07%. With the calculation of the annual prevalences, it was evident the gradual reduction of infection in the population of Itajaí, that was 81.3% in 1992, declining to 33% in the year of 2016. When classifying the prevalence of infection by gender, it was higher in males (53.59%), and gender distribution by age group showed no statistically significant difference among genders between the ages of 40 and 80 years. In relation to the age group, the highest prevalence was in the group between 40 and 49 years. CONCLUSION: Although this study is retrospective and based on endoscopic database analysis, without access to clinical data of patients such as prior use of proton pump inhibitor and antibiotics to endoscopy, its results are important because they may reflect the current panorama of Helicobacter pylori infection in the city under study, where it has been presenting a gradual reduction of prevalence over the years, with current rates similar to that of developed countries (33%). Future studies are needed to confirm our data.

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Epidemiology and geographical distribution of gastrointestinal parasitic infection in humans in Slovakia

Helminthologia ◽

10.1515/helmin-2016-0035 ◽

2016 ◽

Vol 53 (4) ◽

pp. 309-317 ◽

Cited By ~ 10

Author(s):

A. Dudlová ◽

P. Juriš ◽

S. Jurišová ◽

P. Jarčuška ◽

V. Krčméry

Keyword(s):

Ascaris Lumbricoides ◽

Statistical Significance ◽

Parasitic Infection ◽

Giardia Intestinalis ◽

Eastern Region ◽

Age Group ◽

Blastocystis Hominis ◽

Helminthic Infections ◽

High Statistical Significance ◽

Protozoan Infections

Summary Examinations of the set of 2,760 samples of human stools revealed the current epidemiological situation in the occurrence of gastrointestinal parasitoses in Slovakia. Prevalence of gastrointestinal parasitic infection was P = 6.81 % out of which the protozoan infections was P = 2.64 % and helminthiases P = 4.17 %, in the representation of endoparasitic species Entamoeba coli, Giardia intestinalis, Blastocystis hominis, Endolimax nana, Ascaris lumbricoides, Trichuris trichiura and Enterobius vermicularis. The species with the highest proportion from the protozoa was Entamoeba coli (P = 0.79 %) and from the helminths Ascaris lumbricoides (P = 3.73 %). The highest prevalence of protozoan infections (P = 3.27 %) was found in the age group 8 – 18 yearly and helminthic infections (P = 5.84 %) in the lowest age group of children at the age of 1 month to 7 years. Almost regularly, there was most frequently infection with Endolimax nana, Giardia intestinalis and Ascaris lumbricoides. By comparison of all age categories, a high statistical significance of differences in the prevalence of helminthiases was found, which most frequently infected children aged from 1 month to 7 years (X2, p≤ 0.0001). The statistical significance of differences in the incidence of protozoan infections (X2, p≤ 0.01) and helminthiases (X2, p≤ 0.0001) was recorded between the compared regions of Slovakia (Western, Central and Eastern Slovakia) with the highest prevalence in the eastern region of Slovakia.

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Safety of Family Replacement Donors vs. Voluntary Non-Remunerated Donors in Komfo Anokye Teaching Hospital, Ghana: A Comparative Study

Journal of Medical and Biomedical Sciences ◽

10.4314/jmbs.v4i1.2 ◽

2015 ◽

Vol 4 (1) ◽

pp. 11-16

Author(s):

O Addai-Mensah ◽

PA Bashiru ◽

EE Dogbe

Keyword(s):

Hepatitis B ◽

Teaching Hospital ◽

Blood Donors ◽

Blood Donation ◽

Age Groups ◽

Rapid Test ◽

Developed Countries ◽

Sub Saharan Africa ◽

Age Group ◽

Cross Sectional

Blood safety remains a challenge to many countries in sub-Saharan Africa including Ghana due to poorly planned blood donation exercises in the various communities. Blood and its products usual-ly come from two main sources; voluntary non-remunerated donors (VNRD) and family replace-ment donors (FRD). In Ghana, and in many developing countries, FRDs seem to be the major source of blood supply whilst in developed countries VNRDs are the major source. This study de-termined and compared the prevalence of four transfusion transmissible infections (TTIs); HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), and Treponema palladium (TP) among FRDs and VNRDs at the Komfo Anokye Teaching Hospital to compare the safety of blood from these two groups. This cross-sectional study was undertaken at the transfusion medicine unit (TMU) of the Komfo Anokye Teaching Hospital between March and May 2014. A total of 400 blood donors (200 FRDs and 200 VNRDs) were enrolled in this study after obtaining written informed consent. Blood samples from each of the donors were then tested for HIV, hepatitis B and C, and syphilis using rapid test kits. ABO and Rhesus blood groups were also determined for all the samples. Prev-alence of TTIs was higher among FRDs (23.5%) than in VNRDs (3.5%) with males (47) been more infected than females (7). Age group 21- 30 years was the most infected, followed by age groups 31- 40 years, 11- 20 years, 41- 50 years and 51- 60 years respectively. FRDs among the younger age group, 17- 30 years, were also more infected than their VNRD counterparts. Repeat blood donors among the VNRD group, were found to be safer than their first-time counterparts. Overall, TTIs were significantly higher in the FRD group than in the VNRD group. The prevalence rates of all the infections tested were higher in the FRD group compared to the VNRD group. FRDs were the higher risk population for TTIs in comparison to VNRDs. VNRDs should therefore be encouraged to donate blood regularly.Keywords: Transfusion Transmissible Infections, HBsAg, HCV, HIV, Treponema pallidum

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Prevalence of melancholy in swat valley, Pakistan

MOJ Biology and Medicine ◽

10.15406/mojbm.2021.06.00148 ◽

2021 ◽

Vol 6 (4) ◽

pp. 148-156

Keyword(s):

Sleep Disorder ◽

Simple Formula ◽

Age Groups ◽

Developed Countries ◽

World Health ◽

Age Group ◽

Complex Mechanism ◽

Depressed Individual ◽

Swat Valley ◽

Health Organization

Melancholy is major mental challenges that is characterize by sadness, sleep disorder, decrease energy, etc. It also have a great social and mental consequences, it is well know that depression will be the second largest cause of disability globally till 2020. The risk are even higher in developed countries. According to world health organization globally it effect more than 121 million people. Depression is a complex and multi-dimensional anarchy according to it has many faces and cannot be describing by one simple formula because it originate from numerous complex mechanism. Multi-faced nature of depression makes it difficult to find out its etiology. The purpose of this study is to find out the prevalence of melancholy in different age groups and genders in district Swat. Overall 300 samples were collected randomly across different age groups and genders in which we found the prevalence of melancholy were 48.3% in which male depressed individual were 27.6% while female depressed were 20.6%. The number of depressed individual were maximum in age group vary from 10-20 which is 15%. To conclude depression is easily manageable but it need understanding that how to control your feeling and thought and think new and positively.

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