scholarly journals ELISA seroprevalence of Trypanosoma cruzi in a cohort of heart disease patients

2013 ◽  
Vol 7 (04) ◽  
pp. 348-354 ◽  
Author(s):  
Maria-Virginia Rodriguez ◽  
Wendy Yamileth Hernandez ◽  
Adriana N Garcia ◽  
Claudia M Colato ◽  
Patricia G Cardoza ◽  
...  
Keyword(s):  
Heart Disease ◽  
Chagas Disease ◽  
Serological Test ◽  
Chronic Phase ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Reference Hospital ◽  
Two Phases ◽  
And Gender

Introduction: Chagas disease is the most important parasitic disease in El Salvador and Latin America. The disease has two phases: acute and chronic, with an intermediate unspecified phase. The chronic phase develops in 30% of infected persons and its most common manifestation is cardiac disease. This study aimed to obtain reference data for the prevalence of T. cruzi seropositivity in a cohort of cardiac patients. Methodology: A cross-sectional study involving consecutive heart disease patients consulting at the National Hospital Rosales was conducted over a six-month period. Congenital heart disease patients were excluded. A survey, file review, and ELISA serological test were conducted for each subject. Results: Out of 455 subjects, 76 were seropositive for T. cruzi, giving a seropositivity prevalence of 16.7%. The average age of the patients was 58.09 years and the female:male ratio was 2.79:1. No significant difference was found between T. cruzi seropositive and seronegative patients in terms of age and gender. No association between T. cruzi serological status and either area of residence or seeing vectors in the house was found. However, living in the Salvadoran western region during childhood was significantly associated with seropositivity (p = 0.003). Other factors associated with T. cruzi seropositivity included: clinical diagnosis of cardiac Chagas disease; electrocardiographic (ECG) findings of a permanent pacemaker, all atrioventricular (AV) blocks and right bundle branch block; and grade III-IV radiological cardiomegaly. Conclusions: T. cruzi seropositivity prevalence was found to be 16.7% among heart disease patients in a public reference hospital.

Evaluation of the Fibromyalgia and Related Risk Factors in Patients with Advanced Kidney Failure Undergoing Hemodialysis

2021 ◽  
Vol 17 ◽  
Author(s):  
Seyed Mostafa Seyedmardani ◽  
Saeed Abkhiz ◽  
Azadeh Megrazi ◽  
Aarefeh Jafarzade ◽  
Golshan Kamali Zonouz
Keyword(s):  
Risk Factors ◽  
Kidney Failure ◽  
Fibromyalgia Syndrome ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Cross Sectional ◽  
Age And Gender ◽  
Significant Difference ◽  
Symptom Severity Score ◽  
And Gender

Background : Fibromyalgia syndrome (FMS) is defined as widespread and persistent pain in the musculoskeletal system. There are limited reports regarding the prevalence of fibromyalgia syndrome in patients with advanced kidney failure undergoing regular hemodialysis. Therefore, this study aimed to evaluate the prevalence of fibromyalgia syndrome and its risk factors in a large proportion of patients under the hemodialysis condition. Materials and Methods: In this cross-sectional study, 293 patients who were admitted to the hemodialysis ward were evaluated for fibromyalgia syndrome in an educational hospital. The questionnaire was designed according to symptom severity score (SS score) and widespread pain index (WPI) criteria. The correlation between FMS and various variables, including demographic, clinical, and biochemistry biomarkers, was also precisely calculated by logistic regression. Data were analyzed using SPSS v.17 statistics software. Results: The results showed that, of 293 hemodialysis patients, 130 patients (44.4%) had fibromyalgia, the mean age of patients with and without fibromyalgia was 61.09 ± 15.36 and 53.49 ± 15.38 years old, respectively (P = 0.001). Moreover, there was a significant difference in terms of gender among patients with fibromyalgia syndrome (P = 0.001). To note, there was no significant relationship between the kidney failure etiopathogenesis, duration of dialysis, body mass index (BMI), Kt/v index, history of peritoneal dialysis, and laboratory parameters with fibromyalgia in hemodialysis patients (P > 0.05). However, our findings revealed that both age and gender could be considered as the predictor variables associated with fibromyalgia in patients undergoing hemodialysis. Conclusion: Taken together, in this study, we found that age and gender would be the critical factors in terms of the fibromyalgia syndrome in patients undergoing hemodialysis.

scholarly journals Teething Problems and Parental Beliefs in Nigeria

2009 ◽  
Vol 10 (4) ◽  
pp. 75-82 ◽  
Author(s):  
Foluso J. Owotade ◽  
Morenike O. Folayan ◽  
Temitope A. Esan ◽  
Elizabeth O. Oziegbe ◽  
Comfort A. Adekoya-Sofowora
Keyword(s):  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Parental Beliefs ◽  
Cross Sectional ◽  
Socioeconomic Class ◽  
Low Socioeconomic ◽  
Significant Difference ◽  
And Gender ◽  
Symptoms And Signs ◽  
Rule Out

Abstract Aim To determine signs and symptoms associated with teething, parental beliefs about teething, and the effects of socioeconomic status on teething in Nigerian children. Methods and Materials A cross-sectional study consisting of 1,013 mothers of children between the ages four to 36 months who visited the immunization clinics at the Community Health Centres in Ife Central and Ife East Local Government Areas. Data was analyzed using STATA (Intercooled release 9) for Windows. Results A total of 765 mothers (75.5%) reported systemic signs and symptoms in their children. Fever (51.8%), diarrhea (12.5%), and vomiting (2.9%) were the most prevalent symptoms and signs reported. Teething problems were reported by 60% of mothers from a high socioeconomic class, as well as 76.7% and 77.9% from middle and low socioeconomic classes, respectively. Interestingly, 65.5% of mothers believed teething should be accompanied with systemic signs and symptoms such as fever (42.1%), diarrhea (13.9%), and vomiting (0.6%). No significant difference was noted between breastfeeding status, gender of the child, and reported systemic signs and symptoms noticed by the mothers. Conclusion Most mothers in the study reported signs and symptoms adduced to teething in their children irrespective of their beliefs. Fever ranked highest of the signs and symptoms reported. Mothers of children from the high socioeconomic class reported fewer teething symptoms. Breastfeeding status and gender of the child had no effect on teething problems in the children studied. Clinical Significance Most signs and symptoms adduced to teething by parents may actually be due to underlying infections. Thus, there is a need to rule out occult infection during the tooth eruption period. Citation Oziegbe EO, Folayan MO, Adekoya-Sofowora CA, Esan TA, Owotade FJ. Teething Problems and Parental Beliefs in Nigeria. J Contemp Dent Pract 2009 July; (10)4:075-082.

Factors contributing to intentional injuries in Iranian university students

2017 ◽  
Vol 31 (3) ◽  
Author(s):  
Kobra Abedian Kasgary ◽  
Zeinab Hamzehgardeshi ◽  
Zohreh Shahhosseini
Keyword(s):  
University Students ◽  
Demographic Data ◽  
Human Action ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Intentional Injuries ◽  
Significant Difference ◽  
History Of ◽  
And Gender ◽  
The University

Abstract Background Intentional injuries refer to injuries resulting from purposeful human action, whether directed at oneself or others. This study was performed to assess intentional injuries in Iranian university students. Methods This cross-sectional study was carried out with 430 female and male university in three higher education institutions located in the northern part of Iran in the year 2015. Samples were chosen through the stratified cluster random sampling method. They were requested to fill out the demographic data form and the Persian version of the Youth Risk Behavior Survey Questionnaire. Descriptive and inferential statistics were used for data analysis via the SPSS v.13 software. Findings Intentional injuries were more frequent in the male university students than female (p < 0.05). Also, 9.1% and 6.7% of the university students were physically injured or sexually assaulted by a boy/girl friend. No statistically significant difference was reported in dating violence between the male and female university students. The logistic regression test showed that the history of stealing money from parents without their permission, son’s preferences in the family and gender are the most important predisposing factors for the university students’ intentional injury. Conclusion It is suggested that health policy makers consider the role of family in programs that have been designed for improving the health of young people.

scholarly journals Lactulose Hydrogen Breath Test Result Is Associated with Age and Gender

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Carolyn Newberry ◽  
Ann Tierney ◽  
Octavia Pickett-Blakely
Keyword(s):  
Breath Test ◽  
Bacterial Overgrowth ◽  
Gastrointestinal Diseases ◽  
Small Intestinal Bacterial Overgrowth ◽  
Cross Sectional Study ◽  
Hydrogen Breath Test ◽  
Cross Sectional ◽  
Lactulose Hydrogen Breath Test ◽  
Significant Difference ◽  
And Gender

Small intestinal bacterial overgrowth (SIBO) is associated with chronic gastrointestinal diseases and structural/functional abnormalities of the gastrointestinal tract. SIBO’s association with clinical characteristics is unclear. This study investigates the association between clinical factors and SIBO according to lactulose hydrogen breath test (LHBT) result.Methods. A cross-sectional study in a university-based gastroenterology practice was performed. Data was abstracted from the medical records of subjects undergoing LHBT from 6/1/2009 to 6/1/2013. Logistic regression analysis was performed to determine the association between predictor variables: age, sex, body mass index (BMI), and positive LHBT, the outcome of interest.Results. LHBT was performed in 791 subjects. Fifty-four percent had a positive LHBT. There was no statistically significant difference between the LHBT results according to age or BMI. In females, the likelihood of a positive LHBT increased with age (OR 1.02; 95% CI: 1.01–1.03). In males, the likelihood of a positive LHBT result decreased with age (OR 0.98; 95% CI: 0.97–1.00).Conclusion. There was an association between age, with respect to sex, and a positive LHBT. With increased age in females, the odds of a positive LHBT increased, while, in men, the odds of a positive LHBT decreased with age.

scholarly journals Prevalence of nomophobia among the undergraduate medical students of Mandya Institute of Medical Sciences, Mandya

2018 ◽  
Vol 5 (12) ◽  
pp. 5455 ◽  
Author(s):  
Harish B. R. ◽  
Bharath J.
Keyword(s):  
Undergraduate Students ◽  
Mobile Phones ◽  
Cross Sectional Study ◽  
Medical Sciences ◽  
Undergraduate Medical Students ◽  
Cross Sectional ◽  
Significant Difference ◽  
Study Population ◽  
And Gender ◽  
Study Participants

Background: Nomophobia (no mobile phobia), is the fear an individual gets if he is out of mobile phone contact due to no network, has run out of balance or run out of battery; the persons gets anxious, which adversely affects the concentration level of the person. Since the younger generation is the latest consumer of the mobile phones and the under 25 year age group in professional colleges like medical colleges use mobile phones quite frequently this study was conducted to determine the prevalence of nomophobia in the undergraduate students of Mandya Institute of Medical Sciences, Mandya.Methods: This was a cross sectional study conducted at Mandya Institute of Medical Sciences during May 2018 to June 2018. All undergraduate students were included i.e. same as study population (n=450). Data collection was done during June 2018 using structured questionnaire.Results: Mean age of the study participants was 20.1±1.3 years. Majority of the study population were hostelites. Approximate amount of money spent on last recharge/last postpaid bill was INR 354.1±185.0. Main reasons for using smartphones were ‘to call family members’, ‘using internet for academics’ and ‘for social networking’. Prevalence of moderate to severe nomophobia among the study population was 99.0%. No statistical significant difference was observed between gender and nomophobia.Conclusions: Prevalence of nomophobia among undergraduate medical student was 99.0% and majority had moderate level of nomophobia. There was no association between nomophobia and gender, place of present residence, amount of money spent on last recharge. 

scholarly journals Perception of Side Effects of Chemotherapy among Cancer Patients in B.P. Koirala Memorial Cancer Hospital Bharatpur, Nepal

2016 ◽  
Vol 11 (4) ◽  
pp. 14-19 ◽  
Author(s):  
Sharmila Gurung ◽  
Radha Acharya Pandey
Keyword(s):  
Side Effects ◽  
Cancer Patients ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Demand Information ◽  
And Gender ◽  
Loss Of Appetite ◽  
Patient’S Perception

jdjBackground & Objectives: These side effects of chemotherapy affect the patients’ daily life and quality of life adversely. It affects the different body system resulting in physical and non physical (psychosocial) side effects. Cancer patients demand information to understand chemotherapy-related adverse effects and actions to be taken. The aim of the study is to find out the perception of side effects of chemotherapy among cancer patients.Materials and methods: A descriptive cross-sectional study was conducted among 200 cancer patients, using purposive sampling technique and data was collected via face to face interview. Descriptive as well as inferential statistics (T-test) was used to see the significant difference between dependent and independent variables.Results: The overall perceived side effects of chemotherapy include: affects work and home duties (non physical side effect), followed by anxiety, loss of appetite, affects family, affect partner, feel constantly tired (fatigue), affects social activities, feel irritable, nausea and constipation respectively. There is significant difference between perception of side effects of chemotherapy and gender of respondents.Conclusion: The perceptions of side effects of chemotherapy are different from individual to individual. Patient’s perception of side effects of chemotherapy is concerned with non physical side effects rather than physical side effects.Journal of College of Medical Sciences-Nepal, Vol.11(4) 2015: 14-19

Prevalence of Malocclusion in Patients with Thalassemia Major: A Cross-sectional Study

2021 ◽  
Vol 15 (2) ◽  
Author(s):  
Parastoo Namdar ◽  
Atena Shiva ◽  
Tahura Etezadi ◽  
Jamshid Yazdani Charati ◽  
Hossein Karami ◽  
...  
Keyword(s):  
Thalassemia Major ◽  
Cross Sectional Study ◽  
Iranian Population ◽  
Beta Thalassemia ◽  
Practical Training ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Adolescents And Adults ◽  
And Gender

Background: Iran lies in the world's thalassemia belt; accordingly, the beta‐thalassemia gene is carried by 4% of the Iranian population. Due to the dearth of research and literature available on the prevalence of malocclusions in the Iranian population with beta-thalassemia major, this study was conducted to determine the prevalence and severity of facial abnormalities among patients who were referred to Bu-Ali Sina Hospital, Sari, Iran. Methods: This descriptive cross-sectional study was conducted on 200 patients with thalassemia major who were referred to the care unit of Bu-Ali Sina teaching and therapeutic Hospital, Sari, Iran, in 2018. The patients were then visited by a trained dentist who had been given the necessary theoretical and practical training. Malocclusion was classified based on Angle's classification. Spacing, overcrowding, overjet, and overbite were measured, and the distances were recorded based on a checklist. Results: The prevalence of malocclusions obtained was 87.5%, which included malocclusions of Class I (34%), Class II (31%), and Classes III (22%) amongst patients. There was no significant relationship between the type of malocclusion and gender (P = 0.77). Moreover, no significant difference was observed among patients with thalassemia major and different classes of malocclusions in terms of age both in males (P = 0.49) and females (P = 0.58). Conclusions: Malocclusions are common among adolescents and adults with thalassemia, which is not associated with age or gender. Therefore, patients should be regularly visited and followed up by a dentist to manage and control their dental problems. In addition, effective and preventive measures, as well as health education should be seriously considered in these patients.

scholarly journals ANALISIS KADAR ALBUMIN SERUM DENGAN RASIO DE RITIS PADA PENDERITA HEPATITIS B

2018 ◽  
Vol 13 (2) ◽  
pp. 60
Author(s):  
AT. Lopa ◽  
B. Rusli ◽  
M. Arif ◽  
Hardjoeno Hardjoeno
Keyword(s):  
Hepatitis B ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Chronic Phase ◽  
Cross Sectional Study ◽  
Albumin Level ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference

Hepatitis is a inflammation process which may present in an acute or chronic phase. A decrease of serum albumin level may befound in liver disease. Ratio de Ritis in mild hepatitis is < 1 while in alcoholic hepatitis is >1. To analyze serum albumin level withratio de Ritis in hepatitis B patients. A cross sectional study was carried out comprising 46 subjects from October 2005 to August 2006measuring albumin level SGOT and SGPT levels using Lyasis autoanalyzer. Thirty eight males and eight females, the level of serumalbumin decreased with an average of albumin level 2.98 gr/dL (p<0.05). Twenty two subjects showed a ratio de Ritis ≤ 1 with theaverage albumin level 3.00 gr/dL and 24 subjects were included in group ratio de Ritis > 1 with average albumin level 2.96 gr/dL(p value = 0.658). There was a decrease of serum albumin level in hepatitis B patient but no significant difference between decrease ofserum albumin level with ratio of de Ritis ≤ 1 and ratio of de Ritis >1.

scholarly journals Microalbuminuria among children with congenital heart disease seen in Sokoto, North-Western Nigeria

2021 ◽  
Vol 8 (3) ◽  
pp. 414
Author(s):  
Khadijat O. Isezuo ◽  
Usman M. Sani ◽  
Usman M. Waziri ◽  
Bilkisu G. Ilah ◽  
Fatima B. Jiya ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Elisa Technique ◽  
Weak Negative Correlation

Background: Congenital heart disease (CHD) especially cyanotic CHD has been associated with microalbuminuria which is an early marker of glomerular nephropathy but this has hardly been studied in African children. The aim of this study was to compare mean microalbuminuria levels and associations among children with acyanotic CHD, cyanotic CHD and normal controls.Methods: Forty-one (41) children comprising 19 acyanotic CHD, 14 cyanotic CHD and 8 without CHD aged 1 to 15 years were recruited in a cross-sectional study. Quantitative urinary microalbuminuria was measured by ELISA technique. Positive result was microalbuminuria of 30-300 mcg/mgCr. Mean levels were compared by student t-test and analysis of variance (ANOVA). Statistical significance was taken at p<0.05.Results: There were 22 (53.7%) females and 19 (46.3%) males. Mean level of microalbuminuria was highest in those with cyanotic CHD at 147.7±78.8 mcg/mgCr, followed by those with acyanotic CHD at 111.8±61.5 mcg/mgCr and lowest in those without CHD at 67.3±31.6 mcg/mgCr. There was significant difference between the groups with CHD and those without CHD (F=4.1, p=0.03) and microalbuminuria had a significant but weak negative correlation with oxygen saturation implying that microalbuminuria increased with worsening cyanosis.Conclusions: Microalbuminuria was high among the patients with CHD, though higher in cyanotic patients warranting closer follow up of these patients.

scholarly journals PCR Detection of HHV8 DNA in the Saliva of Removable Denture Wearers Compared to Dentate Cases in Shiraz, South of Iran

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Reza Derafshi ◽  
Jannan Ghapanchi ◽  
Fahimeh Rezazadeh ◽  
Mohammad Hasan Kalantari ◽  
Amir Mosahebi Naeeni ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Dna Amplification ◽  
Cross Sectional Study ◽  
Case Group ◽  
Cross Sectional ◽  
Exact Test ◽  
Removable Denture ◽  
Significant Difference ◽  
False Result ◽  
And Gender

Background and aim. Removable dentures may act as reservoir for pathogens that can cause serious infections. Human herpesvirus 8 (HHV8) is an oncogenic virus that was found in the saliva more than genital secretions. Thus, this study was designed to evaluate HHV8 in the saliva of patients with removable dentures. Method and material. In this cross-sectional study from March-July 2019, saliva samples were collected from 50 denture wearers as a case group and 50 ages and gender matched dentate subjects as a control. Whole-mouth saliva, parotid saliva, buccal, and palatal exfoliates were collected and processed for HHV8-DNA amplification by nested PCR. A confirmatory real-time PCR was also performed in order to prevent false result. Result. In the denture wearers, HHV8 DNA was detected in 11 cases. Two of the controls amplified HHV8 DNA. Fisher’s exact test demonstrates a significant difference between virus infection and using removable dentures (p=0.015). Conclusion. Our findings suggested that HHV8 detection could be associated with use of denture.

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